LOCUS       NM_001290397            4804 bp    mRNA    linear   ROD 02-APR-2024
DEFINITION  Mus musculus myeloblastosis oncogene-like 1 (Mybl1), transcript
            variant 2, mRNA.
ACCESSION   NM_001290397 XM_006495462
VERSION     NM_001290397.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4804)
  AUTHORS   Xu,J., Wang,B. and Zhang,D.
  TITLE     LncRNA ENSMUST00000171502 Induced by HIF-1alpha Ameliorates
            Ischemic Acute Kidney Injury via Targeting the miR-130b-3p/Mybl-1
            Axis
  JOURNAL   Cells 11 (23), 3747 (2022)
   PUBMED   36497007
  REMARK    GeneRIF: LncRNA ENSMUST00000171502 Induced by HIF-1alpha
            Ameliorates Ischemic Acute Kidney Injury via Targeting the
            miR-130b-3p/Mybl-1 Axis.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4804)
  AUTHORS   Yu,T., Biasini,A., Cecchini,K., Saflund,M., Mou,H., Arif,A.,
            Eghbali,A., de Rooij,D., Weng,Z., Zamore,P.D. and Ozata,D.M.
  TITLE     A-MYB/TCFL5 regulatory architecture ensures the production of
            pachytene piRNAs in placental mammals
  JOURNAL   RNA 29 (1), 30-43 (2022)
   PUBMED   36241367
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   3  (bases 1 to 4804)
  AUTHORS   Maezawa,S., Sakashita,A., Yukawa,M., Chen,X., Takahashi,K.,
            Alavattam,K.G., Nakata,I., Weirauch,M.T., Barski,A. and
            Namekawa,S.H.
  TITLE     Super-enhancer switching drives a burst in gene expression at the
            mitosis-to-meiosis transition
  JOURNAL   Nat Struct Mol Biol 27 (10), 978-988 (2020)
   PUBMED   32895557
  REMARK    GeneRIF: Super-enhancer switching drives a burst in gene expression
            at the mitosis-to-meiosis transition.
REFERENCE   4  (bases 1 to 4804)
  AUTHORS   Liang,M., Wang,H., He,C., Zhang,K. and Hu,K.
  TITLE     LncRNA-Gm2044 is transcriptionally activated by A-MYB and regulates
            Sycp1 expression as a miR-335-3p sponge in mouse
            spermatocyte-derived GC-2spd(ts) cells
  JOURNAL   Differentiation 114, 49-57 (2020)
   PUBMED   32585553
  REMARK    GeneRIF: LncRNA-Gm2044 is transcriptionally activated by A-MYB and
            regulates Sycp1 expression as a miR-335-3p sponge in mouse
            spermatocyte-derived GC-2spd(ts) cells.
REFERENCE   5  (bases 1 to 4804)
  AUTHORS   Ozata,D.M., Yu,T., Mou,H., Gainetdinov,I., Colpan,C., Cecchini,K.,
            Kaymaz,Y., Wu,P.H., Fan,K., Kucukural,A., Weng,Z. and Zamore,P.D.
  TITLE     Evolutionarily conserved pachytene piRNA loci are highly divergent
            among modern humans
  JOURNAL   Nat Ecol Evol 4 (1), 156-168 (2020)
   PUBMED   31900453
REFERENCE   6  (bases 1 to 4804)
  AUTHORS   Toscani,A., Mettus,R.V., Coupland,R., Simpkins,H., Litvin,J.,
            Orth,J., Hatton,K.S. and Reddy,E.P.
  TITLE     Arrest of spermatogenesis and defective breast development in mice
            lacking A-myb
  JOURNAL   Nature 386 (6626), 713-717 (1997)
   PUBMED   9109487
REFERENCE   7  (bases 1 to 4804)
  AUTHORS   Latham,K.E., Litvin,J., Orth,J.M., Patel,B., Mettus,R. and
            Reddy,E.P.
  TITLE     Temporal patterns of A-myb and B-myb gene expression during testis
            development
  JOURNAL   Oncogene 13 (6), 1161-1168 (1996)
   PUBMED   8808690
REFERENCE   8  (bases 1 to 4804)
  AUTHORS   Sitzmann,J., Noben-Trauth,K. and Klempnauer,K.H.
  TITLE     Expression of mouse c-myb during embryonic development
  JOURNAL   Oncogene 11 (11), 2273-2279 (1995)
   PUBMED   8570177
REFERENCE   9  (bases 1 to 4804)
  AUTHORS   Trauth,K., Mutschler,B., Jenkins,N.A., Gilbert,D.J., Copeland,N.G.
            and Klempnauer,K.H.
  TITLE     Mouse A-myb encodes a trans-activator and is expressed in
            mitotically active cells of the developing central nervous system,
            adult testis and B lymphocytes
  JOURNAL   EMBO J 13 (24), 5994-6005 (1994)
   PUBMED   7813437
REFERENCE   10 (bases 1 to 4804)
  AUTHORS   Mettus,R.V., Litvin,J., Wali,A., Toscani,A., Latham,K., Hatton,K.
            and Reddy,E.P.
  TITLE     Murine A-myb: evidence for differential splicing and
            tissue-specific expression
  JOURNAL   Oncogene 9 (10), 3077-3086 (1994)
   PUBMED   8084617
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158790.5 and AC103620.12.
            
            On Mar 13, 2014 this sequence version replaced XM_006495462.1.
            
            Transcript Variant: This variant (2) lacks an alternate in-frame
            exon in the 3' coding region, compared to variant 1. The encoded
            protein (isoform 2) is shorter than isoform 1.
            
            Sequence Note: This RefSeq record was created from genomic sequence
            data because no single transcript from the same strain was
            available for the full length of the gene. The extent of this
            transcript is supported by transcript alignments and orthologous
            data.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849374, SAMN00849380
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-275               AC158790.5         128968-129242       c
            276-381             AC158790.5         122320-122425       c
            382-453             AC158790.5         121751-121822       c
            454-546             AC158790.5         119114-119206       c
            547-767             AC158790.5         116594-116814       c
            768-942             AC158790.5         114669-114843       c
            943-1014            AC158790.5         112130-112201       c
            1015-1119           AC158790.5         110818-110922       c
            1120-1353           AC103620.12        169694-169927       c
            1354-1722           AC103620.12        167389-167757       c
            1723-1865           AC103620.12        165167-165309       c
            1866-1980           AC103620.12        164523-164637       c
            1981-2097           AC103620.12        163962-164078       c
            2098-2202           AC103620.12        163634-163738       c
            2203-4804           AC103620.12        158833-161434       c
FEATURES             Location/Qualifiers
     source          1..4804
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 2.08 cM"
     gene            1..4804
                     /gene="Mybl1"
                     /gene_synonym="A-myb; G1-419-6; repro9"
                     /note="myeloblastosis oncogene-like 1"
                     /db_xref="GeneID:17864"
                     /db_xref="MGI:MGI:99925"
     exon            1..275
                     /gene="Mybl1"
                     /gene_synonym="A-myb; G1-419-6; repro9"
                     /inference="alignment:Splign:2.1.0"
     CDS             256..2331
                     /gene="Mybl1"
                     /gene_synonym="A-myb; G1-419-6; repro9"
                     /note="isoform 2 is encoded by transcript variant 2;
                     myb-related protein A; myb-like protein 1"
                     /codon_start=1
                     /product="myb-related protein A isoform 2"
                     /protein_id="NP_001277326.1"
                     /db_xref="CCDS:CCDS69861.1"
                     /db_xref="GeneID:17864"
                     /db_xref="MGI:MGI:99925"
                     /translation="MAKRSRSEDEDDDLQYADHDYEVPQQKGLKKLWNRVKWTRDEDD
                     KLKKLVEQHGTDDWTLIASHLQNRSDFQCQHRWQKVLNPELIKGPWTKEEDQRVIELV
                     QKYGPKRWSLIAKHLKGRIGKQCRERWHNHLNPEVKKSSWTEEEDRIIYEAHKRLGNR
                     WAEIAKLLPGRTDNSIKNHWNSTMRRKVEQEGYLQDGIKSERSSSKLQHKPCATMDHL
                     QTQNQFYIPVQIPGYQYVSPDGNCVEHVQTSAFIQQPFVDEDPDKEKKIKELELLLMS
                     AENEVRRKRLPPQPGSFSSWSGSFLMDDSMSNTLNNLEEHTTEFYSMDENQTVSAQQN
                     SPTKFLAVEANAVLSSLQTIPEFAETLELIESDPVAWSDVTSFDLSDAAASPVKSTPV
                     KLMRIQHNEGAMECQFNVSLVLEGKKNSRNGGDSEAIPLTSPNVVKFSTPPTILRKKK
                     RIRVGQSAGSELGDGSLSEVGNAALKHTPVKTLPFSPSQFFNTCPGNEQLNIENPSFT
                     STPICGQKVLITTPLQKEATPKDQKENVGFRTPTIRRSILGTTPRTPTPFKNALAAQE
                     KKYGPLKIVSQPLAFLEEDIREVLKEETGTDIFLKEEDEPAYKSCKQEHSASVKKVRK
                     SLALESWDKEEPGTQLLTEDISDMQSNCEWETVVYGKTEDQLIMTEQARRYLSTYTAT
                     SSTSRALIL"
     exon            276..381
                     /gene="Mybl1"
                     /gene_synonym="A-myb; G1-419-6; repro9"
                     /inference="alignment:Splign:2.1.0"
     exon            382..453
                     /gene="Mybl1"
                     /gene_synonym="A-myb; G1-419-6; repro9"
                     /inference="alignment:Splign:2.1.0"
     exon            454..546
                     /gene="Mybl1"
                     /gene_synonym="A-myb; G1-419-6; repro9"
                     /inference="alignment:Splign:2.1.0"
     exon            547..767
                     /gene="Mybl1"
                     /gene_synonym="A-myb; G1-419-6; repro9"
                     /inference="alignment:Splign:2.1.0"
     exon            768..942
                     /gene="Mybl1"
                     /gene_synonym="A-myb; G1-419-6; repro9"
                     /inference="alignment:Splign:2.1.0"
     exon            943..1014
                     /gene="Mybl1"
                     /gene_synonym="A-myb; G1-419-6; repro9"
                     /inference="alignment:Splign:2.1.0"
     exon            1015..1119
                     /gene="Mybl1"
                     /gene_synonym="A-myb; G1-419-6; repro9"
                     /inference="alignment:Splign:2.1.0"
     exon            1120..1353
                     /gene="Mybl1"
                     /gene_synonym="A-myb; G1-419-6; repro9"
                     /inference="alignment:Splign:2.1.0"
     exon            1354..1722
                     /gene="Mybl1"
                     /gene_synonym="A-myb; G1-419-6; repro9"
                     /inference="alignment:Splign:2.1.0"
     exon            1723..1865
                     /gene="Mybl1"
                     /gene_synonym="A-myb; G1-419-6; repro9"
                     /inference="alignment:Splign:2.1.0"
     exon            1866..1980
                     /gene="Mybl1"
                     /gene_synonym="A-myb; G1-419-6; repro9"
                     /inference="alignment:Splign:2.1.0"
     exon            1981..2097
                     /gene="Mybl1"
                     /gene_synonym="A-myb; G1-419-6; repro9"
                     /inference="alignment:Splign:2.1.0"
     exon            2098..2202
                     /gene="Mybl1"
                     /gene_synonym="A-myb; G1-419-6; repro9"
                     /inference="alignment:Splign:2.1.0"
     exon            2203..4804
                     /gene="Mybl1"
                     /gene_synonym="A-myb; G1-419-6; repro9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcacgcctc ctgacatgtc cagggcatcc ctggccgggc ccggccgcgg ctaggagcag
       61 tgggtcttgg tccgcccctc tgtccctcag tcccgcctgg ccctgacctg accgggcctg
      121 ctttccgctc tcggtcacct gagggaagga gttggggaag cggcgggtgg gtctcggaga
      181 gggagcattg gccccaggct ggaggaggct gaccccgcgt ccccgcccag cccgcgccta
      241 tgcggtactt gaaggatggc gaagaggtcg cgcagtgagg acgaggatga tgaccttcaa
      301 tatgctgatc atgattatga agtacctcaa caaaaaggac tgaaaaaact ctggaacaga
      361 gtaaaatgga caagagatga ggatgacaag ttaaagaagt tggttgaaca acacggaact
      421 gatgattgga ctctaattgc tagtcatctt caaaatcgtt ctgattttca gtgccaacat
      481 cgatggcaga aggttttaaa tccagaattg ataaagggtc cttggactaa ggaagaagat
      541 cagagggtta ttgaattagt tcagaaatat gggccaaaaa ggtggtcttt aattgcaaaa
      601 catttaaaag gaagaatagg caagcagtgc agagaaagat ggcacaatca cctgaaccct
      661 gaagtgaaga agtcttcctg gacagaagaa gaagacagga tcatatatga agcacacaag
      721 cgcctgggaa accgttgggc cgagattgct aagttacttc ctggaaggac tgataattct
      781 atcaaaaatc attggaattc taccatgcga agaaaagtgg aacaggaggg ctatttacaa
      841 gatggaataa aatcagagcg gtcttcatca aaacttcaac acaaaccttg tgcgactatg
      901 gaccatttgc aaacccagaa tcagttttac attcctgttc agatccctgg gtatcagtat
      961 gtgtcgcctg atggcaattg tgttgaacat gttcagacat ctgcctttat tcagcaaccc
     1021 tttgttgatg aagatcctga taaagaaaaa aaaataaagg agctcgagtt gcttcttatg
     1081 tcagccgaga atgaagttag aaggaagagg cttccacctc aacctggaag cttttctagc
     1141 tggtctggta gtttcctcat ggatgatagt atgtctaaca cactgaataa tctggaggaa
     1201 cacactactg agttttatag catggatgaa aatcagactg tttctgctca gcagaattca
     1261 cccacaaagt tcctagctgt agaagcaaat gccgtgctgt cttctctaca gaccatccca
     1321 gaattcgcag aaactctgga actaattgaa tcggatcctg tagcatggag tgatgttacc
     1381 agttttgatc tttctgatgc tgctgcttct cctgtcaagt ctactccagt taaattaatg
     1441 agaattcaac ataatgaagg agccatggaa tgccagttta acgtcagtct tgtacttgaa
     1501 gggaaaaaga acagtcgtaa tggtggagac agtgaagcta ttcctttaac atccccaaat
     1561 gtggtcaagt ttagcactcc tccaaccatc ctcagaaaga agaaaagaat tcgagtgggt
     1621 cagtctgcag gcagtgagct tggcgatggc tcacttagcg aagttggtaa tgcagcactc
     1681 aaacacacac cagtgaaaac actaccattt tctccttctc agttttttaa cacatgtcct
     1741 ggaaatgaac aacttaatat agaaaaccct tcctttacat caaccccaat ttgtgggcag
     1801 aaagttctca ttacaactcc tcttcagaag gaagcaaccc ccaaagatca aaaagaaaat
     1861 gtaggattca gaactcctac tattagaaga tctatactgg gcaccacacc aagaactcct
     1921 actcctttta agaatgcact tgctgctcag gaaaaaaaat atggacctct taaaattgtg
     1981 tcccagccac ttgccttttt ggaagaagac attcgagaag ttttaaaaga agaaactgga
     2041 acagatatat tcctcaaaga ggaagatgaa cctgcttata aaagctgcaa acaggagcac
     2101 tctgcatctg tgaagaaggt cagaaaatcc cttgccttag agagctggga caaagaagaa
     2161 ccagggactc aactgctaac tgaagacatt tcagacatgc agtcaaattg tgaatgggaa
     2221 acagtggtat atgggaagac agaagaccaa cttatcatga ctgaacaagc gagaagatat
     2281 ctgagtactt acacagctac cagcagcaca tcaagagctc taatactcta actgttacta
     2341 aagctgataa aatgccctac ccctttactg tattttatgc taaattaggt tgcaatgaaa
     2401 tttgtctcaa ttaattcttt taaaggtttt aatacatccc taaaatggtt cacgtttttt
     2461 tctatattga acaggcaaaa aactaataag ctacttaaag taaggggtag gcaaatttat
     2521 tatttatatg tttaagaaat gagagtttta aaatttgttt taaagaacaa aatgggaaaa
     2581 taagcatgtt tctggatatt ccatagtaaa ttctcacata atttctttac aggatatatg
     2641 ttgctactgt ctcaaggctg tagtctgtta taaacaagtt aagtatgtgt gacctctgaa
     2701 agtctacatt taggaagcac agaggcttta tgaagtactt ttgcatgtgt gctgatttac
     2761 taagactacc attcataaag aaacacagtg ggaaggagtc tcaaggaagc tagaagttgc
     2821 actactaatt ttggtatttt tcagaaacaa tgaaattaac tacagtgtta aggatattta
     2881 tttgtgcata gtactaaaaa tgcattgaaa atgggctttt tcttactagt aaagagtcag
     2941 tatttcttca taagtctcag aagagctgag aattttgttg aatgtattgt acagtatata
     3001 ggagcaagaa aactttgtaa attggaaaga tgtctgtttt tataacttat tttcattttt
     3061 aaagcttaaa tgtagatatt tatatataca gggtgtctag aagccagtgt tgtttcttgc
     3121 cattacagct aacatagtaa acaataactt tgactttcaa gtatgaaata gttaagttat
     3181 agctgcaaag aatacaatat ctaaactgta tgtcacatct acctaaatat tgcactatat
     3241 cctttaaatc atgttggttt taaagtagtt ctaaaatgta ctaaataata atttaatatt
     3301 ttctttttaa attatattgg agggtcatat aaattaatct ggtgaattgt atatgtgttt
     3361 gaaattttca ttttgtttaa aaaacaatac ggtaccttgt tccctaaaac agtctgcact
     3421 tagaagttta ttgtatttac tcaatgtttc agaagtagaa aatattatct ttatttatac
     3481 aaatattttt gtccttttat aaatgttttg tgtttccaga ttacaacatt tgcttcagtt
     3541 gcctgtttag gtgtttgcac ttattttatc tctttttgaa agaatgtctt tgcttatgtg
     3601 gtagagattt tatgtaattt tttgagatgt ataatggtgt gctgtcaacc taaacactga
     3661 caggcaaata gaattgtaca ctgtagtttg aattatttat aattgacaca ctctctccct
     3721 ctccactcct gaagtatgct gctatagaaa gtagcagaat cggcttgctg ctatgagaga
     3781 tggaaagagc gaccaccact tgcactgtgt gaaaagataa gcaaatgatg gcacgttctc
     3841 aagttaacta atggattcaa ctattcccaa gcagattctt acaaagacca aaacaccact
     3901 atgcctcaaa accaaaccaa acagcttaag atttttaaaa ctctatttat ctgttaatag
     3961 aaatgggact actgaatatt ttaatgccta gttcttcaac agtagaccta aagggtttta
     4021 agctttaaat ccaattgcta gtttttgcat actatatgtt agtgagaagt aaagaatatg
     4081 tgtggtggta ttaagattat gccttcttga taacaatagg taaaacaatt tgaatcttct
     4141 tagcatgtta aatgtttatt ttttctaatt aatgaacttc tcacagaaat tttgctttgt
     4201 aaaaccaatg attgtggaaa aaaatctata tatcatttca gttactttgg ggtaacaata
     4261 gcacataatt ccttttttaa aaaatgtagc cttcagctga ttggatgtaa taatctccag
     4321 tggccaaagt atataactca gacacgttac atattctaaa acataatttt tcttgagcat
     4381 taagttaaca caaatgttaa tgtattatac ataagcttca gcttatggga cagagtacat
     4441 atttgggttg gtattggttg aatcctccag ttaactgctt tgttgttgtt tttttttttt
     4501 tttttttttt ttgcaagatt tgtaatcata aaactgttag gcatcttaag tcatcttttt
     4561 ctactgttca tttatattct tcagttttct gaagatgcca gacgtacagg tagcagccat
     4621 tcatgcatgg aaactgactt cacacatacc aatactgcat tttgttgtaa ggttttcaca
     4681 ttaatacagc aattacactg attaaattga gtttttttaa tatatgaaaa actttgcatt
     4741 gtaagagaat cttgcagaca atgttgaaat ctattaacat ccaaataaaa gcatctgtgt
     4801 acaa
//
