LOCUS       NM_175184               4995 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus multivesicular body subunit 12B (Mvb12b), mRNA.
ACCESSION   NM_175184 XM_992753
VERSION     NM_175184.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4995)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4995)
  AUTHORS   Nandakumar,R., Tschismarov,R., Meissner,F., Prabakaran,T.,
            Krissanaprasit,A., Farahani,E., Zhang,B.C., Assil,S., Martin,A.,
            Bertrams,W., Holm,C.K., Ablasser,A., Klause,T., Thomsen,M.K.,
            Schmeck,B., Howard,K.A., Henry,T., Gothelf,K.V., Decker,T. and
            Paludan,S.R.
  TITLE     Intracellular bacteria engage a STING-TBK1-MVB12b pathway to enable
            paracrine cGAS-STING signalling
  JOURNAL   Nat Microbiol 4 (4), 701-713 (2019)
   PUBMED   30804548
  REMARK    GeneRIF: Multivesicular body protein MVB12b is a target for
            TANK-binding kinase 1 phosphorylation, which is essential for the
            sorting of DNA into extracellular vesicles and stimulation of
            bystander cells.
REFERENCE   3  (bases 1 to 4995)
  AUTHORS   Batsukh,T., Schulz,Y., Wolf,S., Rabe,T.I., Oellerich,T., Urlaub,H.,
            Schaefer,I.M. and Pauli,S.
  TITLE     Identification and characterization of FAM124B as a novel component
            of a CHD7 and CHD8 containing complex
  JOURNAL   PLoS One 7 (12), e52640 (2012)
   PUBMED   23285124
REFERENCE   4  (bases 1 to 4995)
  AUTHORS   Sultana,D.A., Tomita,S., Hamada,M., Iwanaga,Y., Kitahama,Y.,
            Khang,N.V., Hirai,S., Ohigashi,I., Nitta,S., Amagai,T.,
            Takahashi,S. and Takahama,Y.
  TITLE     Gene expression profile of the third pharyngeal pouch reveals role
            of mesenchymal MafB in embryonic thymus development
  JOURNAL   Blood 113 (13), 2976-2987 (2009)
   PUBMED   19164599
REFERENCE   5  (bases 1 to 4995)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Kitamura,H., Nakagawa,T., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of FLJ
            genes: the complete nucleotide sequences of 110 mouse
            FLJ-homologous cDnas identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (2), 127-135 (2004)
   PUBMED   15449545
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL845360.10 and BX649361.2.
            
            On Mar 21, 2007 this sequence version replaced NM_175184.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC059907.1, AK131113.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-627               AL845360.10        146376-147002       c
            628-750             AL845360.10        133394-133516       c
            751-858             AL845360.10        99215-99322         c
            859-955             AL845360.10        93593-93689         c
            956-1085            AL845360.10        86738-86867         c
            1086-1208           AL845360.10        84104-84226         c
            1209-1303           AL845360.10        61801-61895         c
            1304-1359           AL845360.10        14046-14101         c
            1360-1419           AL845360.10        11365-11424         c
            1420-4995           BX649361.2         32762-36337         c
FEATURES             Location/Qualifiers
     source          1..4995
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 22.51 cM"
     gene            1..4995
                     /gene="Mvb12b"
                     /gene_synonym="2610200O14Rik; 2610528K11Rik; Fam125b"
                     /note="multivesicular body subunit 12B"
                     /db_xref="GeneID:72543"
                     /db_xref="MGI:MGI:1919793"
     exon            1..627
                     /gene="Mvb12b"
                     /gene_synonym="2610200O14Rik; 2610528K11Rik; Fam125b"
                     /inference="alignment:Splign:2.1.0"
     exon            628..750
                     /gene="Mvb12b"
                     /gene_synonym="2610200O14Rik; 2610528K11Rik; Fam125b"
                     /inference="alignment:Splign:2.1.0"
     exon            751..858
                     /gene="Mvb12b"
                     /gene_synonym="2610200O14Rik; 2610528K11Rik; Fam125b"
                     /inference="alignment:Splign:2.1.0"
     exon            859..955
                     /gene="Mvb12b"
                     /gene_synonym="2610200O14Rik; 2610528K11Rik; Fam125b"
                     /inference="alignment:Splign:2.1.0"
     exon            956..1085
                     /gene="Mvb12b"
                     /gene_synonym="2610200O14Rik; 2610528K11Rik; Fam125b"
                     /inference="alignment:Splign:2.1.0"
     exon            1086..1208
                     /gene="Mvb12b"
                     /gene_synonym="2610200O14Rik; 2610528K11Rik; Fam125b"
                     /inference="alignment:Splign:2.1.0"
     exon            1209..1303
                     /gene="Mvb12b"
                     /gene_synonym="2610200O14Rik; 2610528K11Rik; Fam125b"
                     /inference="alignment:Splign:2.1.0"
     exon            1304..1359
                     /gene="Mvb12b"
                     /gene_synonym="2610200O14Rik; 2610528K11Rik; Fam125b"
                     /inference="alignment:Splign:2.1.0"
     exon            1360..1419
                     /gene="Mvb12b"
                     /gene_synonym="2610200O14Rik; 2610528K11Rik; Fam125b"
                     /inference="alignment:Splign:2.1.0"
     exon            1420..4995
                     /gene="Mvb12b"
                     /gene_synonym="2610200O14Rik; 2610528K11Rik; Fam125b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttgccccca ggcctctgtg ggtaaatcat ttgcccagca agaggggcaa gctgagacct
       61 gctctgagag tggggtcagt ctgaggcccg gctgcaccgc attaggttag ccggattgtg
      121 ggcagagcag aggggatcgc cccggggtgc agtcaagcct acaagggaca ggtgggaagg
      181 cgtctctgca aagggccact ccgggcctgc aggcctgggt gtcagagcgt cttgcaggga
      241 cctacagctg ggctgagcgg tggacgaggg ggacggcgag gcctagcaga gccgagcgga
      301 ggccgactgg gggcggggac cgagggcacc gggggccaca gggcggtgcg ctcccgggct
      361 ccgccgcagg ctgcacgccc ctcccgcccc ggccccggcc cgagccgctg ctgccgccgc
      421 cgccgtcgct gccgccgcca ggccgcgccc cgcccctcgc cgccgccgct cccggggagg
      481 ctgcgctcga gctgcggcgc cggctgcagc cgcctgggcc ccgggcccgg ctcctcccgc
      541 gccgcccggg cgatgagaag ctgcttctgc gtcagacgga gccgggaccc gccgccgccg
      601 cagccgccgc cgccccagcg gggaacagac caagccacca tgcccgaagt caaggagctt
      661 tcagaagcct tgccagagac accgatggac cccatcacgg gagttggggt ggtggcttcc
      721 cggaaccgag caccaacagg ctacgacgtg gttgcgcaga cagcagatgg cgtggatgct
      781 gatctctgga aggacggctt attcaagtcc aaggttacca gatacctgtg tttcacaaga
      841 tcattttcta aagaaaatag tcatttgggg aatgtgctgg tggacatgaa gctcatcgat
      901 gtcaaggaca cattgcctgt gggcttcatc cccatccaag agaccgtgga tacacaggag
      961 gtggtcttta ggaagaagcg gctctgcatt aagtttatcc cccgggattc aactgaagct
     1021 gccatctgtg acattcgcat catgggccgg accaagcagg caccgcccca gtacacgttt
     1081 atcggggaac tgaacagcat gggcatctgg taccgaatgg gcagagtgcc aagaaaccat
     1141 gactcgtctc agcccaccac gccctcccag tcatcagcct cttctacccc agccccaaac
     1201 cttcccaggc acatctccct aacactaccg gctaccttcc ggggcagaaa caacaccagc
     1261 acagactatg agtaccagct ctccaatcta tatgccatat cagcaatgga tggtgtgcct
     1321 tttatgattt cagagaagtt ttcctgcatt ccagaaagta tgcagccctt tgatctcttg
     1381 ggaatcacca tcaagtctct ggcagaaatt gaaaaggagt acgagtacag cttccgcacc
     1441 gagcagagcg cagcagctcg actcccaccc agccctaccc ggtgccagca gatcccccaa
     1501 tcctgaggag cccacagcct cctgggggag aagacatctc ctacccggtg cccagactac
     1561 tgatggggtg gctggggtga gagtcactcc ctccctcacc tgcccgttct gcttgccctg
     1621 ctcactggcc acgagactct gggcagctgc ttggtcatgt gtggtcatca gctcgcccgc
     1681 tgagacttcc ctgcctccct gggaccgttg ttcataattg tgactaatgt atgtgctgtt
     1741 agtgaccaga ggctcctgtg tgatgaccac ttaccccgcc aagaaagaaa actccttcct
     1801 tacctggact cacccatgag gggcccaggc acacactcca gccgcccagt gacacccact
     1861 ggctcccctc aactgaccgt cacctaccac agaaatccca caaagccact agctccctcc
     1921 tgggacattc cagggttgat tgcttcactt aggaccctgc aagatccact gatggcctct
     1981 gacccagcta cctgggaaca agcgccactc gccagcaggc tccagtggcc cacacatgca
     2041 tttcatgacg gcactaagca gcaggactaa gatgcacttg agacaactgt ggactcttcc
     2101 ccctttccac acactggacg tccagagagc atagatggga ccccgctttc tatggaggtg
     2161 actgggtgcc tacctggatg gaaacttggc tgctagggta ctatgcccag tcacaggtgc
     2221 caattcccac aaagggctca tctgtggagt gtccgacgac agacgacagc tccataggcc
     2281 tctgcctggt gacctgacct ggtggcagct ggctctgaga agaacagtac agaggcacca
     2341 actcgtcaca gccagaccca ccccaccatc tagaaggcac cttccaccag ggagctgctg
     2401 ttttgaaaag cccttctgtc ccaggcctca gaatttgggc caggacattt cacaggtgtc
     2461 aacctgaggt gccaagttga accctccatg tgtcgccatg agaacagtag tcactgctgt
     2521 cccagctctc agcctcacca ccatgcgctg ctttgccacc attggctttt agggctggaa
     2581 tgacactggt ctccagagca tctgtggatg tgaagatctg cccagtggtt agaggccatg
     2641 ggcagctact tcaccagctg gtacaaacct ctccagtcac agctctatag agacagctgg
     2701 gtgtccaagg tgcaaaagga tcaggagcaa gaacaagcca acaagatggc gtgagctggg
     2761 gcagggccaa aaatacctca ccagcctaca ccagcccctc ctccgtccca gaccctcagg
     2821 cccagtcagc cagtctttct gcttgatggt acttcatttc tatgtgtcag gaagggtcac
     2881 cttgcttcct cccctcagat gtgagcacac cctatggggt acccatcaac cccttgcctc
     2941 tgggccccac atcctccggg tagcagaggt ccatagagtc aacatagaca tctctagcaa
     3001 aacctagtgc cacgctggtg ctcaaaggag ctaataaact gacctaagac tgctccacca
     3061 gctggggtcc caaggatctg tgtctgcggc tgcaggtgtg acatcaagtg gcttgtgtgg
     3121 cctgaggccc aagagagggg ttgaccaccg ttgtctgagt taaccgggaa ggttgggcac
     3181 aaagttctgg actctcctaa cctcttcatt gaagtctgta cactttggcc actctttctg
     3241 ttcctcggtt atgaaatcac ttctgccaca gggagccagg tggccctcct cttccttgga
     3301 ggagaatgtg gcttctctga agctctcgaa ggtcctggcc tggaagtgca aaaccgaaga
     3361 ctgtgggcct gttagtgatc cagaggccaa gtgaggggat tcctggagaa agatctagtg
     3421 ctttgcagcc catgcgtgca ctcccacagg actcagcccc tggggggagg gcaaagcgcc
     3481 cactcggagc tggagcagtc tccggatgga cggacggacg gatggttgct gcacacttag
     3541 ctgaagaaga accctgactg agaatgttgt agcactgaca gcttctagct tttgaggcgt
     3601 tgaggacgac ttggtgtctg tggtaggttc caggttgcac ccaacccctg gtttcttgtc
     3661 ttctggtgat ggtaatgatc gtgtgtgctt acccatgccc gtcttatgtg gacccagtag
     3721 acccagacct gacggtagag ctgtggctca cagcagcact gagtggcctt tgggtaccat
     3781 gtggcaggca cactgtcaga tgagcacaag gagacgtgaa gagccaaacc tctcccatgg
     3841 gtctccccct cccctaccag catgtcccaa actgctactg tccctgcaag cacacacatc
     3901 tctcttgaaa tgactaacca gagcacagtt ccctatcccc accgtcccct ctgaaaactt
     3961 ggttccttcc tgagggcctt ggaaatggca catgggtaac aagtggggag ggggttgggg
     4021 gtggggggag ggttgttcca ggctcacttg caaatttatc gtaagaccaa atctaagaat
     4081 tcctgtcagc ctatctctgc cacatggaga gccccgctct cctcggggga aacatgagag
     4141 agaaccatga ctcttcttcc tggtggtcag cagcatatgg ccacctgtgg ccaaggtcat
     4201 gctgaagccc ctcggtcaga aggacgtcca gcaggggact ggggtcctga gcgcacacac
     4261 cctcccttcc actgggcttg gccatcttaa gcacatttcc tgtcatcccc caaacaagcc
     4321 cagcagtggg tgcttttgcc ctctcacatg aggagcctga ggcatggcta caagcttgcc
     4381 agtggcacag acagaatctg accacaaaga ccctgggcca accacccagc ctttgtgtct
     4441 gccctgtggg ctttcttctg ccgtggagat gccatcacgc tgtggtagtg gtccctggca
     4501 tgggtcaggc tgagagtctg tctgactgtc ctgtgtgccc gcccacactg agggctcccc
     4561 agcctcagag catcttctgc cccacttctg gcctcctggc cagggaggag gtagaaaggg
     4621 ccttggtgtg gcgctgagcc atgaagggct gaactcacag aagtggttag tgtccagcca
     4681 agccctggag cctgatgacg aggctgggct cccattcctg ctcccagctc cctcaggtga
     4741 cccgggtgcc ccagccttct ccacctgctc tgggcatgag cccttgaaca attgcagcat
     4801 ctgcacctgg agacaaggct ttgttcccct tcaaaagctt atgaactgct gggccaccgt
     4861 gtggcgctgg gacaaggacc ttaggcacag ctgccttcct gtgtatttat tcaaggtgac
     4921 tgcttggcaa agggaggtct caatgtgtga ctgtatctta atataatttg ttaaataaat
     4981 gtttgtttta acctc
//
