LOCUS       NM_001347131             887 bp    mRNA    linear   ROD 05-AUG-2023
DEFINITION  Mus musculus major urinary protein 8 (Mup8), mRNA.
ACCESSION   NM_001347131 XM_006537510
VERSION     NM_001347131.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 887)
  AUTHORS   Markiewicz-Potoczny M, Lobanova A, Loeb AM, Kirak O, Olbrich T,
            Ruiz S and Lazzerini Denchi E.
  TITLE     TRF2-mediated telomere protection is dispensable in pluripotent
            stem cells
  JOURNAL   Nature 589 (7840), 110-115 (2021)
   PUBMED   33239785
REFERENCE   2  (bases 1 to 887)
  AUTHORS   Charkoftaki G, Wang Y, McAndrews M, Bruford EA, Thompson DC,
            Vasiliou V and Nebert DW.
  TITLE     Update on the human and mouse lipocalin (LCN) gene family,
            including evidence the mouse Mup cluster is result of an
            'evolutionary bloom'
  JOURNAL   Hum Genomics 13 (1), 11 (2019)
   PUBMED   30782214
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 887)
  AUTHORS   Jiang J, Creasy KT, Purnell J, Peterson ML and Spear BT.
  TITLE     Zhx2 (zinc fingers and homeoboxes 2) regulates major urinary
            protein gene expression in the mouse liver
  JOURNAL   J Biol Chem 292 (16), 6765-6774 (2017)
   PUBMED   28258223
REFERENCE   4  (bases 1 to 887)
  AUTHORS   Kwak J, Josue J, Faranda A, Opiekun MC, Preti G, Osada K, Yamazaki
            K and Beauchamp GK.
  TITLE     Butylated hydroxytoluene is a ligand of urinary proteins derived
            from female mice
  JOURNAL   Chem Senses 36 (5), 443-452 (2011)
   PUBMED   21398415
REFERENCE   5  (bases 1 to 887)
  AUTHORS   Logan DW, Marton TF and Stowers L.
  TITLE     Species specificity in major urinary proteins by parallel evolution
  JOURNAL   PLoS One 3 (9), e3280 (2008)
   PUBMED   18815613
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 887)
  AUTHORS   Chamero P, Marton TF, Logan DW, Flanagan K, Cruz JR, Saghatelian A,
            Cravatt BF and Stowers L.
  TITLE     Identification of protein pheromones that promote aggressive
            behaviour
  JOURNAL   Nature 450 (7171), 899-902 (2007)
   PUBMED   18064011
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL772327.4.
            
            On Nov 16, 2016 this sequence version replaced XM_006537510.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CA462835.1, CA457078.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-167               AL772327.4         28126-28292
            168-301             AL772327.4         28631-28764
            302-375             AL772327.4         29533-29606
            376-486             AL772327.4         30240-30350
            487-588             AL772327.4         30693-30794
            589-634             AL772327.4         30959-31004
            635-887             AL772327.4         31794-32046
FEATURES             Location/Qualifiers
     source          1..887
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 32.83 cM"
     gene            1..887
                     /gene="Mup8"
                     /gene_synonym="Gm12809; Mup5"
                     /note="major urinary protein 8"
                     /db_xref="GeneID:100041687"
                     /db_xref="MGI:MGI:3709619"
     exon            1..167
                     /gene="Mup8"
                     /gene_synonym="Gm12809; Mup5"
                     /inference="alignment:Splign:2.1.0"
     CDS             72..614
                     /gene="Mup8"
                     /gene_synonym="Gm12809; Mup5"
                     /note="major urinary protein (Mup) gene family member;
                     major urinary protein 5"
                     /codon_start=1
                     /product="major urinary protein 8 precursor"
                     /protein_id="NP_001334060.1"
                     /db_xref="CCDS:CCDS84740.1"
                     /db_xref="GeneID:100041687"
                     /db_xref="MGI:MGI:3709619"
                     /translation="MKMLLLLCVGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILAS
                     DKREKIEDNGNFRLFLEQIRVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTY
                     DGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHG
                     ILRENIIDLSNANRCLQARE"
     exon            168..301
                     /gene="Mup8"
                     /gene_synonym="Gm12809; Mup5"
                     /inference="alignment:Splign:2.1.0"
     exon            302..375
                     /gene="Mup8"
                     /gene_synonym="Gm12809; Mup5"
                     /inference="alignment:Splign:2.1.0"
     exon            376..486
                     /gene="Mup8"
                     /gene_synonym="Gm12809; Mup5"
                     /inference="alignment:Splign:2.1.0"
     exon            487..588
                     /gene="Mup8"
                     /gene_synonym="Gm12809; Mup5"
                     /inference="alignment:Splign:2.1.0"
     exon            589..634
                     /gene="Mup8"
                     /gene_synonym="Gm12809; Mup5"
                     /inference="alignment:Splign:2.1.0"
     exon            635..887
                     /gene="Mup8"
                     /gene_synonym="Gm12809; Mup5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagtggagt gtagccacga tcacaagaaa gacgtggtcc tgacagacag acaatcctat
       61 tccctaccaa aatgaagatg ctgctgctgc tgtgtgtggg actgacccta gtgtgtgtcc
      121 atgcagaaga agctagttct acgggaagga actttaatgt agaaaagatt aatggggaat
      181 ggcatactat tatcctggcc tctgacaaaa gagaaaagat agaagataat ggcaacttta
      241 gactttttct ggagcaaatc cgtgtcttgg agaattcctt agttcttaaa gtccatactg
      301 taagagatga agagtgctcg gaattatcta tggttgctga caaaacagaa aaggctggtg
      361 aatattctgt gacgtatgat ggattcaata catttactat acctaagaca gactatgata
      421 actttcttat ggctcatctc attaacgaaa aggatgggga aaccttccag ctgatggggc
      481 tctatggccg agaaccagat ttgagttcag acatcaagga aaggtttgca caactatgtg
      541 aggagcatgg aatccttaga gaaaatatca ttgacctatc caatgccaat cgctgcctcc
      601 aggcccgaga atgaagaatg gcctgagcct ccagtgttga gtggagactt ctcaccagga
      661 ctccaccatc atcccttcct atccatacag catccccagt ataaattctg tgatctgcat
      721 tccatcctgt ctcactgaga agtccaattc cagtctatcc acatgttacc taggatacct
      781 catcaagaat caaagacttc tttaaatttt tctttgatat acccatgaca atttttcatg
      841 aatttcttcc tcttcctgtt caataaatga ttacccttgc acttaaa
//
