LOCUS       NM_001200006             886 bp    mRNA    linear   ROD 31-MAY-2024
DEFINITION  Mus musculus major urinary protein 17 (Mup17), mRNA.
ACCESSION   NM_001200006 XM_003084575
VERSION     NM_001200006.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 886)
  AUTHORS   Charkoftaki,G., Wang,Y., McAndrews,M., Bruford,E.A., Thompson,D.C.,
            Vasiliou,V. and Nebert,D.W.
  TITLE     Update on the human and mouse lipocalin (LCN) gene family,
            including evidence the mouse Mup cluster is result of an
            'evolutionary bloom'
  JOURNAL   Hum Genomics 13 (1), 11 (2019)
   PUBMED   30782214
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 886)
  AUTHORS   Jiang,J., Creasy,K.T., Purnell,J., Peterson,M.L. and Spear,B.T.
  TITLE     Zhx2 (zinc fingers and homeoboxes 2) regulates major urinary
            protein gene expression in the mouse liver
  JOURNAL   J Biol Chem 292 (16), 6765-6774 (2017)
   PUBMED   28258223
REFERENCE   3  (bases 1 to 886)
  AUTHORS   Logan,D.W., Marton,T.F. and Stowers,L.
  TITLE     Species specificity in major urinary proteins by parallel evolution
  JOURNAL   PLoS One 3 (9), e3280 (2008)
   PUBMED   18815613
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 886)
  AUTHORS   Chamero,P., Marton,T.F., Logan,D.W., Flanagan,K., Cruz,J.R.,
            Saghatelian,A., Cravatt,B.F. and Stowers,L.
  TITLE     Identification of protein pheromones that promote aggressive
            behaviour
  JOURNAL   Nature 450 (7171), 899-902 (2007)
   PUBMED   18064011
REFERENCE   5  (bases 1 to 886)
  AUTHORS   al-Shawi,R., Ghazal,P., Clark,A.J. and Bishop,J.O.
  TITLE     Intraspecific evolution of a gene family coding for urinary
            proteins
  JOURNAL   J Mol Evol 29 (4), 302-313 (1989)
   PUBMED   2514272
REFERENCE   6  (bases 1 to 886)
  AUTHORS   Bishop,J.O., Selman,G.G., Hickman,J., Black,L., Saunders,R.D. and
            Clark,A.J.
  TITLE     The 45-kb unit of major urinary protein gene organization is a
            gigantic imperfect palindrome
  JOURNAL   Mol Cell Biol 5 (7), 1591-1600 (1985)
   PUBMED   4022008
REFERENCE   7  (bases 1 to 886)
  AUTHORS   Sampsell,B.M. and Held,W.A.
  TITLE     Variation in the major urinary protein multigene family in
            wild-derived mice
  JOURNAL   Genetics 109 (3), 549-568 (1985)
   PUBMED   3979814
REFERENCE   8  (bases 1 to 886)
  AUTHORS   Shaw,P.H., Held,W.A. and Hastie,N.D.
  TITLE     The gene family for major urinary proteins: expression in several
            secretory tissues of the mouse
  JOURNAL   Cell 32 (3), 755-761 (1983)
   PUBMED   6831559
REFERENCE   9  (bases 1 to 886)
  AUTHORS   Krauter,K., Leinwand,L., D'Eustachio,P., Ruddle,F. and Darnell,J.E.
            Jr.
  TITLE     Structural genes of the mouse major urinary protein are on
            chromosome 4
  JOURNAL   J Cell Biol 94 (2), 414-417 (1982)
   PUBMED   7107707
REFERENCE   10 (bases 1 to 886)
  AUTHORS   Bennett,K.L., Lalley,P.A., Barth,R.K. and Hastie,N.D.
  TITLE     Mapping the structural genes coding for the major urinary proteins
            in the mouse: combined use of recombinant inbred strains and
            somatic cell hybrids
  JOURNAL   Proc Natl Acad Sci U S A 79 (4), 1220-1224 (1982)
   PUBMED   6951169
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX001066.15.
            
            On Jan 6, 2011 this sequence version replaced XM_003084575.1.
            
            Sequence Note: This RefSeq record was created from genomic sequence
            data to make the sequence consistent with the reference genome
            assembly. The genomic coordinates used for the transcript record
            were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CA462822.1, CB948173.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849386 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-168               BX001066.15        125983-126150       c
            169-302             BX001066.15        125511-125644       c
            303-376             BX001066.15        124669-124742       c
            377-487             BX001066.15        123939-124049       c
            488-589             BX001066.15        123496-123597       c
            590-635             BX001066.15        123287-123332       c
            636-886             BX001066.15        122249-122499       c
FEATURES             Location/Qualifiers
     source          1..886
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 32.89 cM"
     gene            1..886
                     /gene="Mup17"
                     /gene_synonym="100039206; Gm12557; MUP 17"
                     /note="major urinary protein 17"
                     /db_xref="GeneID:100039206"
                     /db_xref="MGI:MGI:3705217"
     exon            1..168
                     /gene="Mup17"
                     /gene_synonym="100039206; Gm12557; MUP 17"
                     /inference="alignment:Splign:2.1.0"
     CDS             73..615
                     /gene="Mup17"
                     /gene_synonym="100039206; Gm12557; MUP 17"
                     /codon_start=1
                     /product="major urinary protein 17 precursor"
                     /protein_id="NP_001186935.1"
                     /db_xref="CCDS:CCDS51198.1"
                     /db_xref="GeneID:100039206"
                     /db_xref="MGI:MGI:3705217"
                     /translation="MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILAS
                     DKREKIEEHGNFRLFLEQIHVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTY
                     DGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHG
                     ILRENIIDLSNANRCLQARE"
     exon            169..302
                     /gene="Mup17"
                     /gene_synonym="100039206; Gm12557; MUP 17"
                     /inference="alignment:Splign:2.1.0"
     exon            303..376
                     /gene="Mup17"
                     /gene_synonym="100039206; Gm12557; MUP 17"
                     /inference="alignment:Splign:2.1.0"
     exon            377..487
                     /gene="Mup17"
                     /gene_synonym="100039206; Gm12557; MUP 17"
                     /inference="alignment:Splign:2.1.0"
     exon            488..589
                     /gene="Mup17"
                     /gene_synonym="100039206; Gm12557; MUP 17"
                     /inference="alignment:Splign:2.1.0"
     exon            590..635
                     /gene="Mup17"
                     /gene_synonym="100039206; Gm12557; MUP 17"
                     /inference="alignment:Splign:2.1.0"
     exon            636..886
                     /gene="Mup17"
                     /gene_synonym="100039206; Gm12557; MUP 17"
                     /inference="alignment:Splign:2.1.0"
     regulatory      863..868
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mup17"
                     /gene_synonym="100039206; Gm12557; MUP 17"
                     /note="hexamer: AATAAA"
     polyA_site      882
                     /gene="Mup17"
                     /gene_synonym="100039206; Gm12557; MUP 17"
                     /note="major polyA site"
ORIGIN      
        1 gggagtggag tgtagccacg atcacaagaa agacgtggtc ctgacagaca gacaatccta
       61 ttccctacca aaatgaagat gctgctgctg ctgtgtttgg gactgaccct agtctgtgtc
      121 catgcagaag aagctagttc tacgggaagg aactttaatg tagaaaagat taatggggaa
      181 tggcatacta ttatcctggc ctctgacaaa agagaaaaga tagaagaaca tggcaacttt
      241 agactttttc tggagcaaat ccatgtcttg gagaattcct tagttcttaa agtccatact
      301 gtaagagatg aagagtgctc cgaattatct atggttgctg acaaaacaga aaaggctggt
      361 gaatattctg tgacgtatga tggattcaat acatttacta tacctaagac agactatgat
      421 aactttctta tggctcacct cattaacgaa aaggatgggg aaaccttcca gctgatgggg
      481 ctctatggcc gagaaccaga tttgagttca gacatcaagg aaaggtttgc acaactatgt
      541 gaggagcatg gaatccttag agaaaatatc attgacctat ccaatgccaa tcgctgcctc
      601 caggcccgag aatgaagaat ggcctgagcc tccagtgttg agtggacact tctcaccagg
      661 actccaccat catcccttcc tatccataca gcatccccag tataaattct gtgatctgca
      721 ttccatcctg tctcactgag aagtccaatt ccagtctatc aacatgttac ctaggatacc
      781 tcatcaagaa tcaaagactt ctttaaattt ctctttgata cacccttgac aatttttcat
      841 gaaattattc ctcttcctgt tcaataaatg attacccttg cactta
//
