LOCUS       NM_001199936             882 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus major urinary protein 16 (Mup16), mRNA.
ACCESSION   NM_001199936
VERSION     NM_001199936.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 882)
  AUTHORS   Charkoftaki,G., Wang,Y., McAndrews,M., Bruford,E.A., Thompson,D.C.,
            Vasiliou,V. and Nebert,D.W.
  TITLE     Update on the human and mouse lipocalin (LCN) gene family,
            including evidence the mouse Mup cluster is result of an
            'evolutionary bloom'
  JOURNAL   Hum Genomics 13 (1), 11 (2019)
   PUBMED   30782214
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 882)
  AUTHORS   al-Shawi,R., Ghazal,P., Clark,A.J. and Bishop,J.O.
  TITLE     Intraspecific evolution of a gene family coding for urinary
            proteins
  JOURNAL   J Mol Evol 29 (4), 302-313 (1989)
   PUBMED   2514272
REFERENCE   3  (bases 1 to 882)
  AUTHORS   Bishop,J.O., Selman,G.G., Hickman,J., Black,L., Saunders,R.D. and
            Clark,A.J.
  TITLE     The 45-kb unit of major urinary protein gene organization is a
            gigantic imperfect palindrome
  JOURNAL   Mol Cell Biol 5 (7), 1591-1600 (1985)
   PUBMED   4022008
REFERENCE   4  (bases 1 to 882)
  AUTHORS   Sampsell,B.M. and Held,W.A.
  TITLE     Variation in the major urinary protein multigene family in
            wild-derived mice
  JOURNAL   Genetics 109 (3), 549-568 (1985)
   PUBMED   3979814
REFERENCE   5  (bases 1 to 882)
  AUTHORS   Shaw,P.H., Held,W.A. and Hastie,N.D.
  TITLE     The gene family for major urinary proteins: expression in several
            secretory tissues of the mouse
  JOURNAL   Cell 32 (3), 755-761 (1983)
   PUBMED   6831559
REFERENCE   6  (bases 1 to 882)
  AUTHORS   Krauter,K., Leinwand,L., D'Eustachio,P., Ruddle,F. and Darnell,J.E.
            Jr.
  TITLE     Structural genes of the mouse major urinary protein are on
            chromosome 4
  JOURNAL   J Cell Biol 94 (2), 414-417 (1982)
   PUBMED   7107707
REFERENCE   7  (bases 1 to 882)
  AUTHORS   Bennett,K.L., Lalley,P.A., Barth,R.K. and Hastie,N.D.
  TITLE     Mapping the structural genes coding for the major urinary proteins
            in the mouse: combined use of recombinant inbred strains and
            somatic cell hybrids
  JOURNAL   Proc Natl Acad Sci U S A 79 (4), 1220-1224 (1982)
   PUBMED   6951169
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CU041251.14 and AW112504.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CA456434.1, CA493817.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849386 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-162               CU041251.14        125149-125310       c
            163-256             CU041251.14        124717-124810       c
            257-315             AW112504.1         507-565             c
            316-810             AW112504.1         11-505              c
            811-882             CU041251.14        121416-121487       c
FEATURES             Location/Qualifiers
     source          1..882
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 32.88 cM"
     gene            1..882
                     /gene="Mup16"
                     /gene_synonym="100039177; Mup6"
                     /note="major urinary protein 16"
                     /db_xref="GeneID:100039177"
                     /db_xref="MGI:MGI:3780250"
     exon            1..162
                     /gene="Mup16"
                     /gene_synonym="100039177; Mup6"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..609
                     /gene="Mup16"
                     /gene_synonym="100039177; Mup6"
                     /note="Major urinary protein 6; MUP 6; Alpha-2U-globulin;
                     Group 1, BS6"
                     /codon_start=1
                     /product="major urinary protein 16 precursor"
                     /protein_id="NP_001186865.1"
                     /db_xref="CCDS:CCDS57278.1"
                     /db_xref="GeneID:100039177"
                     /db_xref="MGI:MGI:3780250"
                     /translation="MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILAS
                     DKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTY
                     DGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHG
                     ILRENIIDLSNANRCLQARE"
     exon            163..296
                     /gene="Mup16"
                     /gene_synonym="100039177; Mup6"
                     /inference="alignment:Splign:2.1.0"
     exon            297..370
                     /gene="Mup16"
                     /gene_synonym="100039177; Mup6"
                     /inference="alignment:Splign:2.1.0"
     exon            371..481
                     /gene="Mup16"
                     /gene_synonym="100039177; Mup6"
                     /inference="alignment:Splign:2.1.0"
     exon            482..583
                     /gene="Mup16"
                     /gene_synonym="100039177; Mup6"
                     /inference="alignment:Splign:2.1.0"
     exon            584..629
                     /gene="Mup16"
                     /gene_synonym="100039177; Mup6"
                     /inference="alignment:Splign:2.1.0"
     exon            630..882
                     /gene="Mup16"
                     /gene_synonym="100039177; Mup6"
                     /inference="alignment:Splign:2.1.0"
     regulatory      857..862
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mup16"
                     /gene_synonym="100039177; Mup6"
                     /note="hexamer: AATAAA"
     polyA_site      882
                     /gene="Mup16"
                     /gene_synonym="100039177; Mup6"
                     /note="major polyA site"
ORIGIN      
        1 ggagtgtagc cacgatcaca agaaagacgt ggtcctgaca gacagacaat cctattccct
       61 accaaaatga agatgctgtt gctgctgtgt ttgggactga ccctagtctg tgtccatgca
      121 gaagaagcta gttctacggg aaggaacttt aatgtagaaa agattaatgg ggaatggcat
      181 actattatcc tggcttctga caaaagagaa aagatagaag ataatggcaa ctttagactt
      241 tttctggagc aaatccatgt cttggagaat tccttagttc ttaaattcca tactgtaaga
      301 gatgaagagt gctccgaatt atctatggtt gctgacaaaa cagaaaaggc tggtgaatat
      361 tctgtgacgt atgatggatt caatacattt actataccta agacagacta tgataacttt
      421 cttatggctc atctcattaa cgaaaaggat ggggaaacct tccagctgat ggggctctat
      481 ggccgagaac cagatttgag ttcagacatc aaggaaaggt ttgcacaact atgtgaggag
      541 catggaatcc ttagagaaaa tatcattgac ctatccaatg ccaatcgctg cctccaggcc
      601 cgagaatgaa gaatggcctg agcctccagt gttgagtgga gacttctcac caggactcca
      661 ccatcatccc ttcctatcca tacagcatcc ccagtataaa ttctgtgatc tgcattccat
      721 cctgtctcac tgagaagtcc aataccagta tatccacatg ttacctagga tacctcatca
      781 agaatcaaag acttctttaa atttctcttt gatacaccct tgacaatttt tcatgaattt
      841 cttcctcttc ctgttcaata aatgattacc cttgcactta aa
//
