LOCUS       NM_001359505            3761 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus microtubule associated tumor suppressor candidate 2
            (Mtus2), transcript variant 3, mRNA.
ACCESSION   NM_001359505 XM_006504894
VERSION     NM_001359505.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3761)
  AUTHORS   Du Puy,L., Beqqali,A., Monshouwer-Kloots,J., Haagsman,H.P.,
            Roelen,B.A. and Passier,R.
  TITLE     CAZIP, a novel protein expressed in the developing heart and
            nervous system
  JOURNAL   Dev Dyn 238 (11), 2903-2911 (2009)
   PUBMED   19806667
  REMARK    GeneRIF: These results suggest a role for CAZIP in development and
            function of the heart and nervous system in vertebrates.
REFERENCE   2  (bases 1 to 3761)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   3  (bases 1 to 3761)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   4  (bases 1 to 3761)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   5  (bases 1 to 3761)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Hara,Y., Nagase,T.,
            Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: I. The complete nucleotide sequences of 100 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 9 (5), 179-188 (2002)
   PUBMED   12465718
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158301.4 and AC109498.10.
            
            On Jan 24, 2023 this sequence version replaced NM_001359505.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK021162.1, BC055016.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849390
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-222               AC158301.4         201664-201885
            223-289             AC158301.4         214022-214088
            290-504             AC158301.4         225296-225510
            505-610             AC158301.4         231905-232010
            611-684             AC109498.10        103786-103859
            685-783             AC109498.10        106932-107030
            784-903             AC109498.10        109017-109136
            904-1001            AC109498.10        112164-112261
            1002-3761           AC109498.10        118840-121599
FEATURES             Location/Qualifiers
     source          1..3761
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 87.82 cM"
     gene            1..3761
                     /gene="Mtus2"
                     /gene_synonym="5730592G18Rik; A730013O20Rik;
                     C130038G02Rik; Cazip; Gm763; mKIAA0774"
                     /note="microtubule associated tumor suppressor candidate
                     2"
                     /db_xref="GeneID:77521"
                     /db_xref="MGI:MGI:1915388"
     exon            1..222
                     /gene="Mtus2"
                     /gene_synonym="5730592G18Rik; A730013O20Rik;
                     C130038G02Rik; Cazip; Gm763; mKIAA0774"
                     /inference="alignment:Splign:2.1.0"
     CDS             139..1215
                     /gene="Mtus2"
                     /gene_synonym="5730592G18Rik; A730013O20Rik;
                     C130038G02Rik; Cazip; Gm763; mKIAA0774"
                     /note="isoform b is encoded by transcript variant 3;
                     microtubule-associated tumor suppressor candidate 2
                     homolog; cardiac zipper protein; tracking protein of 150
                     kDa; microtubule plus-end tracking protein TIP150"
                     /codon_start=1
                     /product="microtubule-associated tumor suppressor
                     candidate 2 homolog isoform b"
                     /protein_id="NP_001346434.1"
                     /db_xref="GeneID:77521"
                     /db_xref="MGI:MGI:1915388"
                     /translation="MQVLPSQPARMGHHCCKPYICLQCLDKTSERALAKEKELSIELA
                     NIRDEVAFNTAKCEKLQKEKETLERRFEEELRRLGWQQQAEVQELQERLQQQFQAESA
                     RLQAEHQDQLLRMRCQHQEQVEDITASHEAALLEMENNHTVAITILQDDHDHKVQELM
                     STHEFEKKELEENFEKLRLTLQDQVDTLTFQSQSLRDRARRFEEALRKTTEEQLEIAL
                     APYQHLEEDMQSLKQVLEMKNQQIHLQEKKIIELEKLVEKNIILEERIQVLQQQNEDL
                     KARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQTGDPTSPIKLS
                     PTSPVYRGSSSGPSSPARVSTTPR"
     exon            223..289
                     /gene="Mtus2"
                     /gene_synonym="5730592G18Rik; A730013O20Rik;
                     C130038G02Rik; Cazip; Gm763; mKIAA0774"
                     /inference="alignment:Splign:2.1.0"
     exon            290..504
                     /gene="Mtus2"
                     /gene_synonym="5730592G18Rik; A730013O20Rik;
                     C130038G02Rik; Cazip; Gm763; mKIAA0774"
                     /inference="alignment:Splign:2.1.0"
     exon            505..610
                     /gene="Mtus2"
                     /gene_synonym="5730592G18Rik; A730013O20Rik;
                     C130038G02Rik; Cazip; Gm763; mKIAA0774"
                     /inference="alignment:Splign:2.1.0"
     exon            611..684
                     /gene="Mtus2"
                     /gene_synonym="5730592G18Rik; A730013O20Rik;
                     C130038G02Rik; Cazip; Gm763; mKIAA0774"
                     /inference="alignment:Splign:2.1.0"
     exon            685..783
                     /gene="Mtus2"
                     /gene_synonym="5730592G18Rik; A730013O20Rik;
                     C130038G02Rik; Cazip; Gm763; mKIAA0774"
                     /inference="alignment:Splign:2.1.0"
     exon            784..903
                     /gene="Mtus2"
                     /gene_synonym="5730592G18Rik; A730013O20Rik;
                     C130038G02Rik; Cazip; Gm763; mKIAA0774"
                     /inference="alignment:Splign:2.1.0"
     exon            904..1001
                     /gene="Mtus2"
                     /gene_synonym="5730592G18Rik; A730013O20Rik;
                     C130038G02Rik; Cazip; Gm763; mKIAA0774"
                     /inference="alignment:Splign:2.1.0"
     exon            1002..3761
                     /gene="Mtus2"
                     /gene_synonym="5730592G18Rik; A730013O20Rik;
                     C130038G02Rik; Cazip; Gm763; mKIAA0774"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1713..1718
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mtus2"
                     /gene_synonym="5730592G18Rik; A730013O20Rik;
                     C130038G02Rik; Cazip; Gm763; mKIAA0774"
                     /note="hexamer: AATGAA"
     polyA_site      1734
                     /gene="Mtus2"
                     /gene_synonym="5730592G18Rik; A730013O20Rik;
                     C130038G02Rik; Cazip; Gm763; mKIAA0774"
     regulatory      3731..3736
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mtus2"
                     /gene_synonym="5730592G18Rik; A730013O20Rik;
                     C130038G02Rik; Cazip; Gm763; mKIAA0774"
                     /note="hexamer: ATTAAA"
     polyA_site      3761
                     /gene="Mtus2"
                     /gene_synonym="5730592G18Rik; A730013O20Rik;
                     C130038G02Rik; Cazip; Gm763; mKIAA0774"
                     /note="major polyA site"
ORIGIN      
        1 gagtcctcct ctctgcaatc gctgaagtta tcaggagaaa taaggtagtc gggagaccac
       61 atggaagttg tgacagctcc caggggctgc cctttgggag ccagcacctc ggctaaggga
      121 ctgcagccga ctcgttgaat gcaggtgctg ccgagccagc ctgccaggat gggccatcac
      181 tgctgcaagc cttatatctg ccttcagtgc ctggataaaa cgagcgaaag agcccttgcg
      241 aaagaaaagg agctgtcaat cgaacttgcc aacatcaggg atgaagttgc cttcaacacc
      301 gccaagtgtg agaagctgca gaaggagaag gagacgctgg agcggcggtt tgaggaggag
      361 ctgaggaggt tgggctggca gcagcaggcg gaggtgcagg agttgcagga gcggctgcag
      421 cagcagttcc aggccgagag cgcgcgtcta caggcggagc atcaggacca gctgctgcgc
      481 atgcgctgcc agcaccagga gcaggtggaa gacatcactg ccagccacga ggctgccctg
      541 ctggagatgg aaaataacca tacggtcgcc atcaccatcc ttcaggatga ccatgatcac
      601 aaagtccaag aactgatgtc tactcatgaa tttgagaaga aggagttgga agaaaacttt
      661 gaaaagctgc ggctgacatt acaggaccag gtggacacgc taacttttca gagccaatct
      721 ctgcgtgaca gagctcggcg ctttgaggaa gctctaagga aaaccacgga ggagcagcta
      781 gagattgcgc tggctccata ccagcacctg gaagaagaca tgcagagcct gaagcaggtg
      841 ctggagatga agaaccagca gatccacctg caggagaaga agatcatcga gctggaaaag
      901 ctggtggaaa agaatatcat cctggaagaa aggatccagg tgctgcagca gcagaatgaa
      961 gacctcaaag cgaggatcga ccagaacaca gttgtcacca gacaactgtc ggaggaaaat
     1021 gcaaacctcc aggaatacgt ggagaaagag acccaggaaa agaagagact gagccgaacc
     1081 aacgaagaac tactttggaa gctccaaacg ggggacccaa ccagcccgat taaactctcc
     1141 cctacatctc cagtgtacag aggctcctcc tctggaccct cctctccggc cagagtcagt
     1201 accacaccta gatgacatca ccctgccacc cataggagct caggcttctg cccatctgag
     1261 ggcgtgctgg ccaggtgccg gtggccacct tgtgcgcatg ctcggtagct gcacagtgcg
     1321 catgctcggt agctgcacaa tgcatcttag gcagcgtcct ctctgaccct tgtgcaagac
     1381 catcctggta ttggcgctta ggaaggtgta agcagcagag tctggtgtcc acaaaaagaa
     1441 aaaaaaatgt tttagtatag tgagaagcaa aagagaaaca actccaattg tccttgagcg
     1501 acgaacttcc atggcagaac tttaggtcag tcacaaacag ctccgttttg aatacacgaa
     1561 accctccttg taccaaccgc cgcatgtgta tatccagatg tgtgggtata caactgtggc
     1621 gattccgaat tgcatttttt tataacgcga tacgctgaca tattttagtg aaggtcagca
     1681 gttttctaac ttgtgcctaa gaattattgg gaaatgaaaa tgcatttcta tctagtttcc
     1741 tggaaatatt tctacccaaa atagagaaga aaagaaggaa agaaagaaag aaaaaaaaag
     1801 aaaaggtaga agcatgccta tctgccaccg agtgatcccc tgcttaacct aaacaccagc
     1861 gatttgtaga tggtaactgc ctttggaaaa atagcttctt agtccaacgt gactggggtc
     1921 actggtaccc cactgcagga tttaattatg acttctccta tcccaaggag gtgaaatgta
     1981 gcggggtggg ggtgggggga actgaggagt catatagtct ggccaatgtt ttcctcctta
     2041 gtgattcatt atcttgaaaa caccagtttt gctccgcccc cccccccaat ggcatcttgg
     2101 aatccatcat caagctagta ttgcgtcctc aggaaaacat gggagcatgt ggcttttgca
     2161 gcgaggatga gcctgaactt ggagaagatc aagaccatgc atggctcatc ttcatgacag
     2221 aggagtctgg tagggccacc atggctccca tcacggcctc tcataggcaa cacccccatt
     2281 ttcagtttgg ttctatgact cgaccccatc accacacaac aagatggctc aggggttcca
     2341 gtcaaggctt ccagaaacca gcctttctct cttggggaaa ggagggaagc cagttctaaa
     2401 ggtgctagat catgtccctt ctgctggagg gtcaccaggg ctgcacctgg tagtagtccc
     2461 atcttagccc cagaaggctc tcccagacaa gggaacgcag tgaaacggcc agccggcatc
     2521 catcagccac tggactggcc tttgactcta acacggtaga aattagacca cgaaaggtat
     2581 tcatgtagtg ctatggaaga ttagaggcat gatccacaaa ggagaagtag ttttaacagt
     2641 caacacagtg ccgataacga tacctttgtt tcctgtatat gacaagagac ccttcacttt
     2701 ctaagcatgg gcctgcctgt ctttgagcat gcccaagatg acaagagcaa tggagccaag
     2761 cagaaatggc ctgggcatgg tgacagcttc tccaaggata cacataactg actcagaggc
     2821 aaatgtggtc tgtatccctt ctatggctct gagttgggcg tccttggcct cggatgcatc
     2881 tgactgtagc cagcttccat gggtcttgcc cattctggag acacacacgg tagatacaca
     2941 gagaagaaac aggtcttttc cctttggctc tgcatgatac tgggatactg agctgggcat
     3001 tccataatag tagcccatgc catgtcagtt acacacacac acacacaaat atttattctt
     3061 ttagcaggca caacctgcag gtataagttt ggttggccac ttagctctcc aagttaggac
     3121 ccgcctccac agctgtacct gctgagggca ggtactcagc aatacagagt tcgatgtgat
     3181 tatagaatgt ggtgcagtat gttaggctgt tgtggtcaaa gtggtagcaa tgttagatct
     3241 atgtaccctc attaggtgga ctagagcttt gccctaatca gcctcgaccc tgggcacttg
     3301 aataaatctc cccatggccc tggcttcgtt tctccatcac agacacccat cacatatggt
     3361 accccacttg aattaagttc tgagatccag gtggccagag ctgctatgat tcctctgcct
     3421 ccatgctgct atgatccgga cctctcggca tggaaacccg agtctgtctc ccttcccagg
     3481 ctggggaact gcgccctccc ctcctgccac agacagacct gccaaacagc tctgttcttc
     3541 atggagtcag gaggtcctgc tggcctgcag caactcagtt gccttgggct gggactgcat
     3601 tcttgtgatg tctggatggg tttggggctg gaggtcaggt actctgggat tagctgaagg
     3661 gggcacagtg ttctttgtcc tgcccctccg gttaactgtg ctccatattt gtgttgaact
     3721 ctaaaagcat attaaagtga acctgaggga ctcccatgat a
//
