LOCUS       NM_001403498            5164 bp    mRNA    linear   ROD 06-AUG-2024
DEFINITION  Mus musculus MTSS I-BAR domain containing 1 (Mtss1), transcript
            variant 3, mRNA.
ACCESSION   NM_001403498
VERSION     NM_001403498.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5164)
  AUTHORS   Kim,N., Li,Y., Yu,R., Kwon,H.S., Song,A., Jun,M.H., Jeong,J.Y.,
            Lee,J.H., Lim,H.H., Kim,M.J., Kim,J.W. and Oh,W.J.
  TITLE     Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal
            extension and steering via activating an autoregulatory factor,
            Mtss1
  JOURNAL   Elife 13, e96891 (2024)
   PUBMED   38526535
  REMARK    GeneRIF: Repulsive Sema3E-Plexin-D1 signaling coordinates both
            axonal extension and steering via activating an autoregulatory
            factor, Mtss1.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5164)
  AUTHORS   Chen,M., Shan,L., Gan,Y., Tian,L., Zhou,J., Zhu,E., Yuan,H., Li,X.
            and Wang,B.
  TITLE     Metastasis suppressor 1 controls osteoblast differentiation and
            bone homeostasis through regulating Src-Wnt/beta-catenin signaling
  JOURNAL   Cell Mol Life Sci 79 (2), 107 (2022)
   PUBMED   35094173
  REMARK    GeneRIF: Metastasis suppressor 1 controls osteoblast
            differentiation and bone homeostasis through regulating
            Src-Wnt/beta-catenin signaling.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5164)
  AUTHORS   Grandits,A.M., Nguyen,C.H., Schlerka,A., Hackl,H., Sill,H.,
            Etzler,J., Heyes,E., Stoiber,D., Grebien,F., Heller,G. and
            Wieser,R.
  TITLE     Downregulation of MTSS1 in acute myeloid leukemia is associated
            with a poor prognosis, chemotherapy resistance, and disease
            aggressiveness
  JOURNAL   Leukemia 35 (10), 2827-2839 (2021)
   PUBMED   33782537
  REMARK    GeneRIF: Downregulation of MTSS1 in acute myeloid leukemia is
            associated with a poor prognosis, chemotherapy resistance, and
            disease aggressiveness.
REFERENCE   4  (bases 1 to 5164)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5164)
  AUTHORS   Chen,J.X., Wang,Y.P., Zhang,X., Li,G.X., Zheng,K. and Duan,C.Z.
  TITLE     lncRNA Mtss1 promotes inflammatory responses and secondary brain
            injury after intracerebral hemorrhage by targeting miR-709 in mice
  JOURNAL   Brain Res Bull 162, 20-29 (2020)
   PUBMED   32442560
  REMARK    GeneRIF: lncRNA Mtss1 promotes inflammatory responses and secondary
            brain injury after intracerebral hemorrhage by targeting miR-709 in
            mice.
REFERENCE   6  (bases 1 to 5164)
  AUTHORS   Callahan,C.A., Ofstad,T., Horng,L., Wang,J.K., Zhen,H.H.,
            Coulombe,P.A. and Oro,A.E.
  TITLE     MIM/BEG4, a Sonic hedgehog-responsive gene that potentiates
            Gli-dependent transcription
  JOURNAL   Genes Dev 18 (22), 2724-2729 (2004)
   PUBMED   15545630
REFERENCE   7  (bases 1 to 5164)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   8  (bases 1 to 5164)
  AUTHORS   Mattila,P.K., Salminen,M., Yamashiro,T. and Lappalainen,P.
  TITLE     Mouse MIM, a tissue-specific regulator of cytoskeletal dynamics,
            interacts with ATP-actin monomers through its C-terminal WH2 domain
  JOURNAL   J Biol Chem 278 (10), 8452-8459 (2003)
   PUBMED   12482861
  REMARK    GeneRIF: tissue-specific regulator of cytoskeletal dynamics that
            interacts with ATP-actin monomers through its C-terminal WH2 domain
REFERENCE   9  (bases 1 to 5164)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   10 (bases 1 to 5164)
  AUTHORS   Paunola,E., Mattila,P.K. and Lappalainen,P.
  TITLE     WH2 domain: a small, versatile adapter for actin monomers
  JOURNAL   FEBS Lett 513 (1), 92-97 (2002)
   PUBMED   11911886
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC112945.10, AC109185.15 and AC158777.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14777534.50885.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-607               AC112945.10        16314-16920         c
            608-669             AC109185.15        8628-8689
            670-743             AC109185.15        11959-12032
            744-828             AC158777.3         75700-75784
            829-920             AC158777.3         77192-77283
            921-995             AC158777.3         79347-79421
            996-1153            AC158777.3         91670-91827
            1154-1261           AC158777.3         93047-93154
            1262-1359           AC158777.3         94649-94746
            1360-1570           AC158777.3         96580-96790
            1571-1690           AC158777.3         99818-99937
            1691-1885           AC158777.3         100740-100934
            1886-2059           AC158777.3         102241-102414
            2060-2267           AC158777.3         102736-102943
            2268-5164           AC158777.3         104130-107026
FEATURES             Location/Qualifiers
     source          1..5164
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 25.09 cM"
     gene            1..5164
                     /gene="Mtss1"
                     /gene_synonym="2310003N14Rik; D130001D01Rik; Mim;
                     mKIAA0429"
                     /note="MTSS I-BAR domain containing 1"
                     /db_xref="GeneID:211401"
                     /db_xref="MGI:MGI:2384818"
     exon            1..607
                     /gene="Mtss1"
                     /gene_synonym="2310003N14Rik; D130001D01Rik; Mim;
                     mKIAA0429"
                     /inference="alignment:Splign:2.1.0"
     exon            608..669
                     /gene="Mtss1"
                     /gene_synonym="2310003N14Rik; D130001D01Rik; Mim;
                     mKIAA0429"
                     /inference="alignment:Splign:2.1.0"
     exon            670..743
                     /gene="Mtss1"
                     /gene_synonym="2310003N14Rik; D130001D01Rik; Mim;
                     mKIAA0429"
                     /inference="alignment:Splign:2.1.0"
     exon            744..828
                     /gene="Mtss1"
                     /gene_synonym="2310003N14Rik; D130001D01Rik; Mim;
                     mKIAA0429"
                     /inference="alignment:Splign:2.1.0"
     exon            829..920
                     /gene="Mtss1"
                     /gene_synonym="2310003N14Rik; D130001D01Rik; Mim;
                     mKIAA0429"
                     /inference="alignment:Splign:2.1.0"
     exon            921..995
                     /gene="Mtss1"
                     /gene_synonym="2310003N14Rik; D130001D01Rik; Mim;
                     mKIAA0429"
                     /inference="alignment:Splign:2.1.0"
     exon            996..1153
                     /gene="Mtss1"
                     /gene_synonym="2310003N14Rik; D130001D01Rik; Mim;
                     mKIAA0429"
                     /inference="alignment:Splign:2.1.0"
     exon            1154..1261
                     /gene="Mtss1"
                     /gene_synonym="2310003N14Rik; D130001D01Rik; Mim;
                     mKIAA0429"
                     /inference="alignment:Splign:2.1.0"
     exon            1262..1359
                     /gene="Mtss1"
                     /gene_synonym="2310003N14Rik; D130001D01Rik; Mim;
                     mKIAA0429"
                     /inference="alignment:Splign:2.1.0"
     exon            1360..1570
                     /gene="Mtss1"
                     /gene_synonym="2310003N14Rik; D130001D01Rik; Mim;
                     mKIAA0429"
                     /inference="alignment:Splign:2.1.0"
     exon            1571..1690
                     /gene="Mtss1"
                     /gene_synonym="2310003N14Rik; D130001D01Rik; Mim;
                     mKIAA0429"
                     /inference="alignment:Splign:2.1.0"
     exon            1691..1885
                     /gene="Mtss1"
                     /gene_synonym="2310003N14Rik; D130001D01Rik; Mim;
                     mKIAA0429"
                     /inference="alignment:Splign:2.1.0"
     exon            1886..2059
                     /gene="Mtss1"
                     /gene_synonym="2310003N14Rik; D130001D01Rik; Mim;
                     mKIAA0429"
                     /inference="alignment:Splign:2.1.0"
     exon            2060..2267
                     /gene="Mtss1"
                     /gene_synonym="2310003N14Rik; D130001D01Rik; Mim;
                     mKIAA0429"
                     /inference="alignment:Splign:2.1.0"
     exon            2268..5164
                     /gene="Mtss1"
                     /gene_synonym="2310003N14Rik; D130001D01Rik; Mim;
                     mKIAA0429"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3019..3024
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mtss1"
                     /gene_synonym="2310003N14Rik; D130001D01Rik; Mim;
                     mKIAA0429"
                     /note="hexamer: AATAAA"
     polyA_site      3044
                     /gene="Mtss1"
                     /gene_synonym="2310003N14Rik; D130001D01Rik; Mim;
                     mKIAA0429"
     regulatory      3128..3133
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mtss1"
                     /gene_synonym="2310003N14Rik; D130001D01Rik; Mim;
                     mKIAA0429"
                     /note="hexamer: ATTAAA"
     polyA_site      3151
                     /gene="Mtss1"
                     /gene_synonym="2310003N14Rik; D130001D01Rik; Mim;
                     mKIAA0429"
     regulatory      5141..5146
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mtss1"
                     /gene_synonym="2310003N14Rik; D130001D01Rik; Mim;
                     mKIAA0429"
                     /note="hexamer: AATAAA"
     polyA_site      5164
                     /gene="Mtss1"
                     /gene_synonym="2310003N14Rik; D130001D01Rik; Mim;
                     mKIAA0429"
                     /note="major polyA site"
ORIGIN      
        1 agagcgagcg cggggccggg cgcacaggag taaaaaggag gcggcggccg cgtctgcgag
       61 caacagatcc gggcgacgcg agctgacctc gtctgctgct gccctttttc gttctctctt
      121 tctttatttt ggagtttcag aaaaaaatta tatttggaag acattttttt ttttttcgta
      181 aatggcgctg gccccgggtc agcgggcggt tttctctgca ccaagatggg cttcgccttt
      241 tccgtcgtgg gcactcttgg tggcttgatt gtcagtcttc tccgggcatt tttgagacca
      301 ggagccgagc actgcacata ggtgactcgc cctccggagc ggctgggcgt cttggattgg
      361 gacttggggg ggcagagtgc agtaaattgc gagcaccgcg tgctctctgc aaaaccggcg
      421 gcgagccgga ggtaggtcgc tcccagggtg aaaccgctcc cgggctgagc gagcccggcc
      481 ccgtgcgcag tgcagccgcc ccgagagcgt gtcctgtccc cgccgcgccg ggaaaatgga
      541 ggctgtgatc gagaaggaat gcagcgcgct tggaggcctc ttccagacca tcatcagcga
      601 catgaagggg agctatccag tttgggaaga cttcataaac aaagccggaa agctacagtc
      661 ccagctgcgg acaacagtag tagcagcagc tgccttcttg gacgcctttc agaaagtggc
      721 tgacatggcc accaacacac gtggtggtac ccgggagatc ggctcagctc tcaccagaat
      781 gtgcatgcgg caccggagca tcgaggccaa gctgaggcag ttctccagtg ctttgatcga
      841 ttgcctgata aacccactgc aagaacaaat ggaggaatgg aagaaagtgg ccaaccagct
      901 ggacaaggac cacgcaaaag aatataagaa agctcgacaa gagataaaaa agaagtcctc
      961 tgacacgctg aagctgcaga agaaggcaaa aaaagggagg ggcgacatcc agcctcagtt
     1021 ggacagcgct ctccaggatg tcaacgataa atacctcctg ttggaggaaa cggagaagca
     1081 ggctgtgcgc aaggcactca tcgaagaacg aggccggttc tgcaccttca tctctatgct
     1141 gcggccagtg atcgaggaag agatttccat gttaggagag attacccacc ttcagaccat
     1201 atcggaggat ctgaagagcc tgaccatgga ccctcacaag ctgccctcct caagtgaaca
     1261 ggtgattttg gacttgaaag gttctgacta tagttggtcc tatcagacgc ctccttcttc
     1321 tcccagtaca actatgtcca gaaagtcaag tgtctgcagc agcctgaaca gcgtcaacag
     1381 cagtgactcc cggtccagtg gctcccactc gcactcgccc agctcgcatt accggtaccg
     1441 cagctctaac ctggcccagc aggcccccgt gaggctgtcc agcgtgtcct cccacgactc
     1501 aggattcata tcccaggacg ccttccagtc caagtcaccc tctcccatgc cacctgaagc
     1561 tgccaaccag aactcgtcca gctcggcctc ctccgaagcg tcggaaacct gccagtcagt
     1621 gagcgagtgc agctccccca cctcagtcag ctcaggctct accatgggcg cctgggtgtc
     1681 cacagagaag ttgtctaatg ggttttctca ctgtagttta tcaagtgagt cccatgcagg
     1741 gcccgtgggt gcaggccctt tccctcattg cctgcctgcc tcccgcctgc tccctcgggt
     1801 cacctctgtc caccttcctg actacgctca ttattacacc attgggcccg gcatgttccc
     1861 gtcatctcag atccctagct ggaaggactg ggcaaagcca ggaccctatg accagccact
     1921 ggtgaacacc ctccagcgcc gcaaagagaa acgtgagcca gactctaatg ggggaggacc
     1981 cactacgaca ggagggccac ctgcaggtgc tgaagaggcg cagagaccaa ggagcatgac
     2041 ggtgtcagct gccaccaggc ctggtgagga gatggcggcc tgtgaggaac tgacactcgc
     2101 cctgtcccgg ggcctccagc tggacgtgca gaggagcagc cgggactcac tacagtgctc
     2161 cagcggctac agcacccaga ccaccacccc gtgctgctct gaggatacca tcccctccca
     2221 aggtacgagg cgcccagctt gccgtccggc tttccgggcg ggtccagttt cagattacga
     2281 ttatttctct gtaagtggcg accaggaggc agagcagcaa gaattcgaca agtcctccac
     2341 cattccaagg aacagtgaca tcagccagtc ttacaggcgg atgttccaag ccaagcgtcc
     2401 agcctcaacg gctggcctac ccaccactct cggacctgct atggtcacac caggggtggc
     2461 gaccatccga cggacccctt ccaccaagcc ttctgtccgc cgggggacca tcggagctgg
     2521 tcctattccc atcaagacac cagtgatccc tgtcaaaacc ccaactgtcc cagacctccc
     2581 tggggttttg ccatcccctc cagatgggcc agaggagcgg ggtgagcaca gccccgagtc
     2641 tccatctgca ggggaggggc cccagggtgt cagcaatata ccctcttcct tgtggagtgg
     2701 ccaagcaccc gtcaaccctc cacttccagg cccaaagccc agtatccctg aggaacacag
     2761 acaggcgatt ccagagagcg aggctgaaga ccaggaaagg gaccccccaa gtgccactgt
     2821 ctccccaggc ccgattccag agagtgaccc cgcagacctg agccccagag aaagtcctca
     2881 gggagaagac atgttgaacg ccatccggag gggcgtgaag ctgaagaaga cgaccaccaa
     2941 cgatcgctca gcaccgcgct tctcttaggt tctcctggtt cccaggagat gctgccagcg
     3001 cgaacgaact ctttaattaa taaagcctaa tttgtcttga tccattccag tctataatca
     3061 agcaaacgat tttgtaggca attcggaatc ctgctctttt caaagtattc gacatcttta
     3121 gataagaatt aaaagcaaca tatgtaattg acataacctt gatcttttaa tttgtaaata
     3181 ttgacggttt ctttctgcat actttaatct tagtttccct tttgattttt ctgaaggtgc
     3241 caaattccat ttaacttttt tacaggtctt tgtaaaattt taaaagcata aaggggaggg
     3301 gggtgggttg ggatgggaac cttggagtaa tttcacaaga ggattacata cttagttgtt
     3361 tttctttttt ttttctcccc tcacgctttt gtagatgcat tgtagttgtc tagtttagaa
     3421 gcaaattcaa gttattttaa tggataaaca caacggataa ggggtgaaac cctcactcac
     3481 atatactgtg ttctggagga gaaacgcagg agtaacagtt gagcagtacg cagagaagga
     3541 aaccggacat ggtggactgt gtggggattg gggggagggc tgggggaggg gcacactgtc
     3601 aacatagcca atcctgttac atttaagagt agccttgtag gttgaatttc cagtagcttc
     3661 atggttaacg catctgaata agccatacta gattgcagtg tttgtttctg taaggttttt
     3721 aaggacttcc tttctcccgg cattcctctt gaccgcacac acagcatcca cacccggtcc
     3781 tgcgcatgct gctgccatgg gtagacatag tcccttcttt actttctcgt ctcttatact
     3841 cacttccact gaatccaaat acatccaaag gggtaaggca attcagaaaa cgtgcaaaca
     3901 ttttaaaatg atagcaggga attcttagat atagaaaatg ccttttactt aactgtgccc
     3961 agcaggctgg gtgcgttgaa aagcccagat attttgaaga aaaaaaaaat tcaaacagat
     4021 ttatcaaggg taaccagctt ggagtctagc aattttgcca atgtgcttac caatttgggg
     4081 gcttgttttt cttcccttcc ttacataagg acagttgatt ggcttctaaa caccggagca
     4141 aagtggattt atttactgtc aactgggagt ctgacttcaa ttcaggcaat gttttttctt
     4201 ctttttcttt ttttctttaa aagtgaattt gtcctttctt tctttaagtg gaagttaaat
     4261 ttgttaaaat gcccatccct aaagtcaaca gagaactgta gatttcaaga gctcacattt
     4321 aaagacagct gttcaaaggg caaggccctc ggcagcacag cagctgacag tacacgcctg
     4381 acattttggg caggagactt ggtgggtccc atgtgctccg cagatctccc gttggctcta
     4441 gcctctgatg acgtaatctt ctactttaac acctcaccac ctcggatgtg agagtaccgt
     4501 tcctctagtc attgctctat agattaacat ttaacactgc tgtgactgat tgctcaaagg
     4561 acattttatg ttatggcttt aaagcagagg catgattatt agaaatgact taagctcttt
     4621 tctttgaaaa acaagctcct tttgcagacg aagcaaacag tagtgcctgt ggtttagccc
     4681 gccaatcttg acgactcaaa gtagctgatg cattgtgcat atgatgcttg agatggtttt
     4741 gcagatgcag acatcgctgc aaggtcattc taatagagac aagcggtatt ttaaaccttt
     4801 gaaaggaatg gatgtaactg tacgttggta cagcttttca cttgtttagt ttttaaacgt
     4861 tagtataatc tgaataaagt taatataaac tgttgccaaa ttcaatgtag aaagaatgtg
     4921 acaaacacct tgggtagttc tgtttgtgtt tttgcatatt gtaaaagcag tgtcacagct
     4981 gaaaatgaac cctttctaaa ggtaaattat tgtgatttag ttgctagttt gtattgagag
     5041 ttgacctctc cctgtgcagt ttttgtttgg aacttgtata gataacagcg tgtaatgtgt
     5101 ccccttctac actgtaacag ttgcttctgc ctaccttata aataaagaat cactaagaaa
     5161 aaga
//
