LOCUS       XM_006539077            6452 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus mechanistic target of rapamycin kinase
            (Mtor), transcript variant X1, mRNA.
ACCESSION   XM_006539077
VERSION     XM_006539077.3
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000070.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Aug 8, 2019 this sequence version replaced XM_006539077.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6452
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="4"
     gene            1..6452
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /note="mechanistic target of rapamycin kinase; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 76 ESTs, 666 long SRA reads, and 100% coverage
                     of the annotated genomic feature by RNAseq alignments,
                     including 40 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:56717"
                     /db_xref="MGI:MGI:1928394"
     CDS             140..5629
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /codon_start=1
                     /product="serine/threonine-protein kinase mTOR isoform X1"
                     /protein_id="XP_006539140.1"
                     /db_xref="GeneID:56717"
                     /db_xref="MGI:MGI:1928394"
                     /translation="MNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNA
                     PRLIRPYMEPILKALILKLKDPDPDPNPGVINNVLATIGELAQVSGLEMRKWVDELFI
                     IIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGT
                     RREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNM
                     GNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPT
                     FLNVIRVCDGAIREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIIL
                     LIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSQGRIVSIKLLAAIQLFGANLDDYLH
                     LLLPPIVKLFDAPEVPLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLDQSPELR
                     STAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHRINHQRYDVLICRIVKGYTLADEEED
                     PLIYQHRMLRSSQGDALASGPVETGPMKKLHVSTINLQKAWGAARRVSKDDWLEWLRR
                     LSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELA
                     LTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKEL
                     EFQKGPTPAILESLISINNKLQQPEAASGVLEYAMKHFGELEIQATWYEKLHEWEDAL
                     VAYDKKMDTNKEDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAA
                     AAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELT
                     AMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQ
                     KILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTA
                     HPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHKQELHKLMARC
                     FLKLGEWQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQN
                     QARDEKKKLRHASGANITNATTAATTAASAAAATSTEGSNSESEAESNENSPTPSPLQ
                     KKVTEDLSKTLLLYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALV
                     EGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKS
                     TTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFG
                     ERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLT
                     QAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSI
                     APSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPT
                     SLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMA
                     PDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMV
                     GYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAME
                     VTGLDGNYRTTCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRT
                     DSYSAGQSVEILDGVELGEPAHKKAGTTVPESIHSFIGDGLVKPEALNKKAIQIINRV
                     RDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW"
ORIGIN      
        1 ggccatgccc acgtggttag ccagactgca gtgcaggtgg tggcagatgt gctcagcaag
       61 ctgcttgtgg ttggcataac agatcctggt ctttgagatc cgcgagctgg ccatctgcac
      121 tgtgggccga ctaagcagca tgaacccagc cttcgtcatg cctttcctgc gcaagatgct
      181 catccagatc ctgacagagc tggagcacag cggcattggg agaatcaagg agcagagcgc
      241 ccgcatgctg gggcacctgg tgtccaacgc cccccggctc atccgcccct acatggagcc
      301 tatcctgaag gctttaattt tgaaactgaa agatccagac cctgacccaa acccgggcgt
      361 gatcaataac gtgttggcca ctataggaga actggctcag gtgagcggcc tggaaatgcg
      421 gaagtgggtg gacgagctct ttatcatcat catggacatg ctgcaggact cctccctgct
      481 ggccaaaagg caggtggctt tgtggaccct gggacagttg gtggccagca ctggctatgt
      541 ggtggagccc tacaggaagt accccacttt gcttgaagtg ctgctgaatt tcctgaagac
      601 ggagcagaac cagggcactc ggagagaggc tatccgagtg ttggggctcc ttggggcttt
      661 ggatccctac aagcacaaag tgaacatcgg catgatcgac cagtcccggg acgcttccgc
      721 tgtcagcctg tcagagtcca agtcaagtca ggattcctct gactacagca ccagtgaaat
      781 gctggtcaac atgggaaacc tgcccctgga cgagttctac cccgctgtgt ccatggtggc
      841 cttgatgcgg atcttccgag atcaatccct ctctcaccac cacaccatgg tggtgcaggc
      901 catcaccttc atcttcaagt ccctggggct caagtgtgtg cagttcctgc cccaggtcat
      961 gcccacattc cttaatgtca tccgagtctg tgatggggcc atccgggaat ttctgttcca
     1021 gcagctgggg atgctggtgt cctttgtgaa gagccacatc cgtccctaca tggatgaaat
     1081 agtcactctc atgagagagt tttgggtcat gaacacgtca atccagagca caatcattct
     1141 tctcattgag cagattgtgg tggctctcgg aggggaattt aagctttatc tgccccagtt
     1201 gatcccacac atgctgcggg tcttcatgca tgacaacagc caaggccgaa tcgtctccat
     1261 caagctgtta gccgcgatcc agctgtttgg cgccaacctg gatgactatc tgcacttgtt
     1321 gttgcctccg attgtgaaat tgtttgatgc ccctgaagtc ccgctgccat caagaaaggc
     1381 agcgctggag acggtggacc gcctgacaga gtccctagac ttcactgact acgcctcccg
     1441 catcattcac ccaatagttc gtacgctaga ccagagccca gagctgcgct ccacagccat
     1501 ggacactctg tcttcgcttg tctttcaact ggggaagaag taccagatct tcattccaat
     1561 ggtgaataaa gtcctcgtgc gacaccggat caaccaccag cgctatgatg tgcttatctg
     1621 cagaatcgtc aaggggtaca cacttgctga tgaggaagaa gaccctttga tttaccagca
     1681 tcgaatgcta aggagcagcc agggagatgc cctggccagt ggaccagttg agacaggacc
     1741 catgaagaaa ctgcatgtca gcaccatcaa cctccaaaag gcctggggag ctgccagaag
     1801 ggtctccaag gacgactggc tggagtggct gaggcgcttg agtctggagc ttctgaagga
     1861 ctcctcatcg ccctccctgc gctcatgctg ggccctggcg caggcctaca accccatggc
     1921 cagggatctc ttcaatgctg cctttgtgtc ctgctggtct gagctgaatg aagaccagca
     1981 agatgagctc atcaggagta ttgagttggc tctcacttct caagacattg ctgaagtcac
     2041 acaaaccctc ctgaacttgg ctgagttcat ggaacacagt gacaagggcc ccctgccgct
     2101 gagagatgac aatggcatcg tgctcctggg tgagagagct gccaagtgcc gggcatatgc
     2161 caaagcactg cactacaaag aactggagtt ccagaaaggg cccacgcctg ccatacttga
     2221 gtccctcatc agcattaaca acaagctcca gcagcctgag gcagcttctg gggtgttgga
     2281 atacgccatg aaacacttcg gagagctgga gatccaggcc acctggtatg agaagctgca
     2341 tgagtgggag gatgctctcg tggcctacga caagaagatg gacacaaaca aggaagaccc
     2401 ggagctgatg ctgggccgaa tgcgctgcct cgaggccttg ggggaatggg gccagcttca
     2461 tcagcagtgc tgtgaaaagt ggactctggt taatgatgag acccaggcta agatggcccg
     2521 gatggctgct gctgcagcgt ggggtttagg tcagtgggac agcatggagg agtacacctg
     2581 catgatccca cgggacaccc acgatggagc cttttacagg gcagtgttgg ctctacatca
     2641 ggatctcttc tccttggccc agcagtgcat tgacaaggcc agggacctgc tggatgcaga
     2701 gctgactgcc atggcaggag agagctacag ccgagcctat ggggccatgg tttcttgcca
     2761 catgctgtcc gagctggaag aggttatcca gtacaaactt gtccctgagc gtcgggagat
     2821 catccggcag atctggtggg agagactgca gggctgccag cgtattgttg aggactggca
     2881 gaaaatcctc atggtccggt cccttgtggt cagccctcat gaggacatga gaacctggct
     2941 caagtacgca agcctgtgtg gcaagagtgg cagactggct cttgctcata aaaccttagt
     3001 gttgctcttg ggagttgatc catctcggca acttgaccat cctctgccaa ccgctcaccc
     3061 tcaagtgacc tatgcctaca tgaagaacat gtggaaaagt gctcggaaga ttgacgcctt
     3121 ccagcacatg caacactttg tgcagaccat gcagcagcag gcccagcatg ccatcgccac
     3181 agaggaccag cagcacaagc aggagctgca taagctcatg gccaggtgtt ttctgaaact
     3241 tggggagtgg cagctgaacc tccagggcat caacgagagc accatcccca aggtgctaca
     3301 gtactacagt gccgccacag agcatgaccg cagctggtac aaggcttggc atgcatgggc
     3361 agtgatgaac ttcgaagcag tgctacacta caaacatcag aaccaagccc gtgatgagaa
     3421 gaagaagctg cgtcatgcca gcggggccaa catcaccaat gccaccactg cagccaccac
     3481 tgcagcctct gctgctgctg ccaccagcac agagggcagc aacagtgaga gtgaagctga
     3541 gagcaatgag aacagcccca ccccgtcccc tctgcagaag aaggtcactg aggatttatc
     3601 caaaactctc ttgttgtaca ctgtccctgc tgttcaaggc ttcttccgtt ctatctcctt
     3661 gtcaagaggc aacaacctcc aggatacact aagagtcctc accctgtggt ttgattatgg
     3721 tcactggcca gatgtcaatg aagccttggt ggaaggggtg aaggccatac agattgacac
     3781 ttggttacag gttatacctc agctcattgc aagaattgac acacccagac ccttggtggg
     3841 ccggctcatt caccagcttc tcacagatat tggtcggtac cacccacagg ccctcatcta
     3901 ccccctgacg gtggcttcta agtctaccac cacagcccgt cacaatgcag ccaacaagat
     3961 cttgaagaac atgtgtgaac acagcaacac gctggtccag caggccatga tggtgagtga
     4021 agagctgatt cgggtagcca tcctctggca tgagatgtgg catgaaggcc tggaagaggc
     4081 atctcgcttg tactttgggg agaggaacgt gaaaggcatg tttgaggtgc tggagcccct
     4141 gcatgctatg atggaacggg gtccccagac tctgaaggaa acatccttta atcaggcata
     4201 tggccgagat ttaatggagg cacaagaatg gtgtcgaaag tacatgaagt cggggaacgt
     4261 caaggacctc acgcaagcct gggacctcta ctatcacgtg ttcagacgga tctcaaagca
     4321 gctaccccag ctcacatccc tggagctgca gtatgtgtcc cccaaacttc tgatgtgccg
     4381 agaccttgag ttggctgtgc caggaacata cgaccccaac cagccaatca ttcgcattca
     4441 atccatagcc ccgtctttgc aagtcatcac atccaagcag aggcctcgga agctgactct
     4501 gatgggcagc aatgggcatg agtttgtttt cctcctgaaa ggccatgaag atctgcggca
     4561 ggatgaacga gtgatgcagc tctttggcct ggtgaacaca ctcctagcca atgaccccac
     4621 ttctcttcgc aagaacctca gcatccagag atacgctgtc atccctctgt ccaccaactc
     4681 gggcctcatt ggctgggtgc cccactgtga cacactgcat gccctcatcc gggactacag
     4741 agagaagaag aagatcctgt tgaacatcga gcatcgcatc atgctgcgga tggctcctga
     4801 ctatgaccac ctgacgttga tgcagaaggt agaggtgttt gagcatgctg tcaacaacac
     4861 agctggggac gacctggcca agctactgtg gctaaaaagc cccagctcgg aggtgtggtt
     4921 tgaccgaaga accaactata cccgctccct ggccgttatg tcgatggtcg gatacatttt
     4981 aggccttgga gacaggcacc catccaatct gatgctggac cggctgagtg ggaagatcct
     5041 gcacattgac tttggggact gctttgaggt cgctatgacc agagagaaat ttccagaaaa
     5101 gattccattt agactaacaa gaatgttgac caatgctatg gaggttacgg gtctggatgg
     5161 caactacaga accacatgcc acaccgtgat ggaagtgctc cgggaacaca aggacagtgt
     5221 catggctgtg ctggaagcct ttgtctatga cccactgctc aactggaggc tgatggacac
     5281 aaataccaaa ggcaataagc ggtcccggac aaggacagac tcctactctg ccggccagtc
     5341 agtagaaatt ttggacggtg tagaacttgg agaaccagcc cataagaaag cagggaccac
     5401 tgtgccagaa tccatccatt cattcattgg agacggtttg gtgaaaccag aagccttaaa
     5461 caagaaagct attcagatta ttaacagggt tcgagataag ctcactggtc gggatttctc
     5521 tcatgatgac actttggatg ttccaaccca agtggagctg cttatcaagc aggcaacatc
     5581 tcacgagaac ctctgccagt gctacattgg ctggtgtccc ttctggtaac tgaggcctgg
     5641 aaaaccacgt cgtctcctcc caggctttag taccttgtct gtgcttccag tggactaaaa
     5701 ccatggacag acagttggac ttgttaaata ttttgaaatg tatatgaaaa gaactactgt
     5761 atattcaaag ttggcttccg ccaacctcct agctgctgtt gaaaagacac tgtcagaaac
     5821 acaaggcttg attcagttcc caggacagtg aaacacagta atccttcaga agccaagcct
     5881 tggattttgg gagaacagaa gatgggtaac tgagaaatac gggttttgac ttaacttaca
     5941 agaaaactca tcataaacat tgctgacaga ataatccagt tggtcctctc aaccaggggc
     6001 tccaacggca aggacacaga ggtcggcact ccactatcct gttacctcac ccgtccctgg
     6061 atgcagtggc gacatttgca ggatgggcca acatggctaa gagagtctgt cttccgcctg
     6121 accccacgat gctgaaactc acaagacctg cccttccagg aggacatttg ttcagaagcc
     6181 tggccaccgg gcatgagcag gtgtgccaag gatctccatg cggggccaca ctggctctac
     6241 tgtgttcagt gagggaggga tatgctgtat ttgcagcagg gactcagaac ataaatgctg
     6301 atcacagagg gacacactag agcaggttgt gagttataag caaagtaaat atccaactaa
     6361 atacacaaag tataaagtaa agccacatct agacaccacg ttgtatctga gtaaattttg
     6421 tgccaataaa tgacatcaga attttaaaag ca
//
