LOCUS       NM_020009               8612 bp    mRNA    linear   ROD 16-FEB-2025
DEFINITION  Mus musculus mechanistic target of rapamycin kinase (Mtor), mRNA.
ACCESSION   NM_020009 XM_207023
VERSION     NM_020009.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8612)
  AUTHORS   Zhao,G., Xie,Y., Lei,X., Guo,R. and Cui,N.
  TITLE     mTOR aggravated CD4+ T cell pyroptosis by regulating the
            PPARgamma-Nrf2 pathway in sepsis
  JOURNAL   Int Immunopharmacol 140, 112822 (2024)
   PUBMED   39096877
  REMARK    GeneRIF: mTOR aggravated CD4[+] T cell pyroptosis by regulating the
            PPARgamma-Nrf2 pathway in sepsis.
            Erratum:[Int Immunopharmacol. 2024 Dec 25;143(Pt 1):113389. doi:
            10.1016/j.intimp.2024.113389.. PMID: 39406572]
REFERENCE   2  (bases 1 to 8612)
  AUTHORS   Witucki,L. and Jakubowski,H.
  TITLE     Homocysteine metabolites impair the PHF8/H4K20me1/mTOR/autophagy
            pathway by upregulating the expression of histone demethylase
            PHF8-targeting microRNAs in human vascular endothelial cells and
            mice
  JOURNAL   FASEB J 38 (18), e70072 (2024)
   PUBMED   39323294
  REMARK    GeneRIF: Homocysteine metabolites impair the
            PHF8/H4K20me1/mTOR/autophagy pathway by upregulating the expression
            of histone demethylase PHF8-targeting microRNAs in human vascular
            endothelial cells and mice.
REFERENCE   3  (bases 1 to 8612)
  AUTHORS   Dong,M.Z., Ouyang,Y.C., Gao,S.C., Gu,L.J., Guo,J.N., Sun,S.M.,
            Wang,Z.B. and Sun,Q.Y.
  TITLE     Protein phosphatase 4 maintains the survival of primordial
            follicles by regulating autophagy in oocytes
  JOURNAL   Cell Death Dis 15 (9), 658 (2024)
   PUBMED   39245708
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 8612)
  AUTHORS   Li,C., Cai,Y., Chen,Y., Tong,J., Li,Y., Liu,D., Wang,Y., Li,Z.,
            Wang,Y. and Li,Q.
  TITLE     ABCG2 shields against epilepsy, relieves oxidative stress and
            apoptosis via inhibiting the ISGylation of STAT1 and mTOR
  JOURNAL   Redox Biol 75, 103262 (2024)
   PUBMED   38981367
  REMARK    GeneRIF: ABCG2 shields against epilepsy, relieves oxidative stress
            and apoptosis via inhibiting the ISGylation of STAT1 and mTOR.
REFERENCE   5  (bases 1 to 8612)
  AUTHORS   Zhao,R., Huang,S., Li,J., Gu,A., Fu,M., Hua,W., Mao,Y., Lei,Q.Y.,
            Lu,B. and Wen,W.
  TITLE     Excessive STAU1 condensate drives mTOR translation and autophagy
            dysfunction in neurodegeneration
  JOURNAL   J Cell Biol 223 (8) (2024)
   PUBMED   38913026
  REMARK    GeneRIF: Excessive STAU1 condensate drives mTOR translation and
            autophagy dysfunction in neurodegeneration.
REFERENCE   6  (bases 1 to 8612)
  AUTHORS   Hentges,K.E., Sirry,B., Gingeras,A.C., Sarbassov,D., Sonenberg,N.,
            Sabatini,D. and Peterson,A.S.
  TITLE     FRAP/mTOR is required for proliferation and patterning during
            embryonic development in the mouse
  JOURNAL   Proc Natl Acad Sci U S A 98 (24), 13796-13801 (2001)
   PUBMED   11707573
REFERENCE   7  (bases 1 to 8612)
  AUTHORS   Liu,J.J. and Wilson,S.E.
  TITLE     Characterization of human and mouse angiopoietin-like factor CDT6
            promoters
  JOURNAL   Invest Ophthalmol Vis Sci 42 (12), 2776-2783 (2001)
   PUBMED   11687517
REFERENCE   8  (bases 1 to 8612)
  AUTHORS   Hentges,K., Thompson,K. and Peterson,A.
  TITLE     The flat-top gene is required for the expansion and regionalization
            of the telencephalic primordium
  JOURNAL   Development 126 (8), 1601-1609 (1999)
   PUBMED   10079223
REFERENCE   9  (bases 1 to 8612)
  AUTHORS   Cohen,J.S.
  TITLE     Provide fluoxetine information vital to clinicians
  JOURNAL   J Clin Psychiatry 56 (12), 591 (1995)
   PUBMED   8530339
REFERENCE   10 (bases 1 to 8612)
  AUTHORS   Chiu,M.I., Katz,H. and Berlin,V.
  TITLE     RAPT1, a mammalian homolog of yeast Tor, interacts with the
            FKBP12/rapamycin complex
  JOURNAL   Proc Natl Acad Sci U S A 91 (26), 12574-12578 (1994)
   PUBMED   7809080
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ130100.1 and BC112904.1.
            
            On Apr 22, 2009 this sequence version replaced NM_020009.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC112904.1, AF152838.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-42                CJ130100.1         1-42
            43-8612             BC112904.1         1-8570
FEATURES             Location/Qualifiers
     source          1..8612
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 78.76 cM"
     gene            1..8612
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /note="mechanistic target of rapamycin kinase"
                     /db_xref="GeneID:56717"
                     /db_xref="MGI:MGI:1928394"
     exon            1..106
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            107..282
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     CDS             121..7770
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /EC_number="2.7.11.1"
                     /EC_number="2.7.10.2"
                     /note="angiopoietin-like factor CDT6; rapamycin target
                     protein 1; mammalian target of rapamycin; FKBP12-rapamycin
                     complex-associated protein; FK506-binding protein
                     12-rapamycin complex-associated protein 1; FK506 binding
                     protein 12-rapamycin associated protein 1; FKBP-rapamycin
                     associated protein (FRAP); mechanistic target of rapamycin
                     (serine/threonine kinase); tyrosine-protein kinase mTOR"
                     /codon_start=1
                     /product="serine/threonine-protein kinase mTOR"
                     /protein_id="NP_064393.2"
                     /db_xref="CCDS:CCDS18937.1"
                     /db_xref="GeneID:56717"
                     /db_xref="MGI:MGI:1928394"
                     /translation="MLGTGPAVATASAATSSNVSVLQQFASGLKSRNEETRAKAAKEL
                     QHYVTMELREMSQEESTRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNST
                     RIGRFANYLRNLLPSSDPVVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGADR
                     NEGRRHAAVLVLRELAISVPTFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLI
                     LTTQREPKEMQKPQWYRHTFEEAEKGFDETLAKEKGMNRDDRIHGALLILNELVRISS
                     MEGERLREEMEEITQQQLVHDKYCKDLMGFGTKPRHITPFTSFQAVQPQQPNALVGLL
                     GYSSPQGLMGFGTSPSPAKSTLVESRCCRDLMEEKFDQVCQWVLKCRSSKNSLIQMTI
                     LNLLPRLAAFRPSAFTDTQYLQDTMNHVLSCVKKEKERTAAFQALGLLSVAVRSEFKV
                     YLPRVLDIIRAALPPKDFAHKRQKTVQVDATVFTCISMLARAMGPGIQQDIKELLEPM
                     LAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPGMPKGLAHQLA
                     SPGLTTLPEASDVASITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKEIRMEAAR
                     TCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDER
                     FDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTE
                     LEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKDPDPDPNPGVINNV
                     LATIGELAQVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVE
                     PYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASA
                     VSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVV
                     QAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLVSFVKSHIRPY
                     MDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSQ
                     GRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEVPLPSRKAALETVDRLTESL
                     DFTDYASRIIHPIVRTLDQSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHRI
                     NHQRYDVLICRIVKGYTLADEEEDPLIYQHRMLRSSQGDALASGPVETGPMKKLHVST
                     INLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNA
                     AFVSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDN
                     GIVLLGERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAASGVLEYA
                     MKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKEDPELMLGRMRCLEALGEWGQLH
                     QQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLAL
                     HQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPE
                     RREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLAL
                     AHKTLVLLLGVDPSRQLDHPLPTAHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQ
                     QAQHAIATEDQQHKQELHKLMARCFLKLGEWQLNLQGINESTIPKVLQYYSAATEHDR
                     SWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKLRHASGANITNATTAATTAASAAAAT
                     STEGSNSESEAESNENSPTPSPLQKKVTEDLSKTLLLYTVPAVQGFFRSISLSRGNNL
                     QDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIH
                     QLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEEL
                     IRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAY
                     GRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLM
                     CRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHE
                     DLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHA
                     LIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLK
                     SPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEV
                     AMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRTTCHTVMEVLREHKDSVMAVLEAFV
                     YDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHKKAGTTVPESIH
                     SFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENL
                     CQCYIGWCPFW"
     exon            283..391
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            392..624
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            625..825
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            826..960
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            961..1236
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1237..1345
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1346..1532
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1533..1661
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1662..1906
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1907..2122
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            2123..2328
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            2329..2451
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            2452..2541
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            2542..2634
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            2635..2769
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            2770..2899
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            2900..3150
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            3151..3237
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            3238..3405
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            3406..3518
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            3519..3681
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            3682..3774
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            3775..3921
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            3922..4064
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            4065..4227
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            4228..4373
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            4374..4449
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            4450..4589
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            4590..4690
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            4691..4806
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            4807..4884
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            4885..4992
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            4993..5118
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            5119..5250
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            5251..5366
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            5367..5484
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            5485..5733
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            5734..5834
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            5835..5931
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            5932..6030
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            6031..6153
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            6154..6336
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            6337..6471
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            6472..6646
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            6647..6782
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            6783..6930
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            6931..7053
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            7054..7136
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            7137..7209
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            7210..7284
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            7285..7420
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            7421..7486
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            7487..7567
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            7568..7648
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            7649..7754
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            7755..8595
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8566..8571
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /note="hexamer: AATAAA"
     polyA_site      8593
                     /gene="Mtor"
                     /gene_synonym="2610315D21Rik; flat; FRAP; Frap1; FRAP2;
                     RAFT1; RAPT1"
                     /note="major polyA site"
ORIGIN      
        1 tccctggcct agaagacagc ggggaaggcg ggtgttgagg ctgggggcct gaagcggcgg
       61 taccggctcc ggcggcggca gctgaggcgg tggccgaagc cgcgcgaacc tcagggcaag
      121 atgcttggga cgggtcctgc cgtggccacc gccagtgccg ccacatctag caacgtgagc
      181 gtcctgcagc agttcgccag tggactgaag agccggaatg aggagaccag ggccaaagca
      241 gccaaggagc tccagcacta cgtcaccatg gagcttcgag agatgagtca ggaggagtct
      301 actcgcttct atgaccagct gaaccatcac atttttgaac tggtttccag ctcagatgcc
      361 aatgagagga agggtggcat cttggccatc gccagcctca taggagtgga aggtgggaat
      421 tccaccagaa ttggcagatt tgccaactac cttcgaaacc tcctcccctc aagcgatcca
      481 gttgtcatgg aaatggcgtc caaggccatt ggccgcctgg cgatggcagg ggacactttc
      541 actgctgaat atgtggagtt tgaagtgaag cgagccttgg agtggctggg tgctgaccga
      601 aatgagggcc ggagacatgc cgctgtcctc gttctccgtg agctggccat cagtgtcccc
      661 accttcttct tccagcaagt tcagcccttc tttgacaaca tttttgtggc tgtgtgggac
      721 cccaagcagg ccatccggga aggcgctgta gcggcccttc gtgcctgtct gattctcacc
      781 acgcagcggg aaccaaagga aatgcagaag cctcagtggt accggcacac atttgaagaa
      841 gcagagaaag gttttgatga gaccctggcc aaagagaagg gtatgaatcg agatgatcga
      901 atccacggag ccttgctgat cctcaacgag ctagttcgta tcagcagcat ggagggagag
      961 cgtctgagag aagagatgga ggagatcacc cagcagcagc tggtgcatga caagtactgc
     1021 aaagacctca tgggcttcgg gaccaagcct cggcacatca cgcccttcac cagtttccag
     1081 gctgtgcagc cccagcagcc gaacgccttg gtgggactgc tggggtacag ctcccctcaa
     1141 ggcctgatgg gatttgggac gtcccccagc cctgccaagt ccactctggt ggaaagccgc
     1201 tgttgcagag acttgatgga agagaaattt gatcaggtgt gccagtgggt gctgaagtgc
     1261 aggagcagca agaactcgct gatccagatg acaatcctta acctgctgcc ccgcctggct
     1321 gcattccgac cgtccgcctt cacagatacc cagtacctcc aggacaccat gaaccatgtc
     1381 ctgagctgtg tcaagaagga gaaggaacgg actgcggcgt tccaggccct ggggctgctt
     1441 tctgtggccg tgaggtcgga gtttaaggtc tacttgcccc gtgtacttga catcatccga
     1501 gcagcgcttc ctccaaagga ctttgcccac aagaggcaga aaaccgtgca ggtggatgcc
     1561 accgtattca cgtgcatcag catgttggca cgagcaatgg ggccgggcat ccagcaggac
     1621 atcaaggagc tgctggagcc catgttggca gtgggcctga gccccgcgct cactgctgtg
     1681 ctctatgacc tgagccggca gattccacag ctgaagaaag atattcagga cggccttctg
     1741 aagatgctgt ccctggtcct tatgcacaaa cccctccggc acccaggcat gcccaaaggc
     1801 ctggctcacc agctggcttc ccctggtctc accaccctcc ctgaggccag cgacgtggcc
     1861 agcatcactc ttgcccttcg aacccttggc agctttgaat ttgaaggcca ctctctgacc
     1921 cagttcgtcc gacactgcgc agatcacttc ctgaacagcg agcacaagga gatccgcatg
     1981 gaagctgctc gcacctgctc ccgcctgctc acaccctcca tccacctcat cagcggccat
     2041 gcccacgtgg ttagccagac tgcagtgcag gtggtggcag atgtgctcag caagctgctt
     2101 gtggttggca taacagatcc tgaccctgat atccgctact gtgtcttggc atccctggac
     2161 gagcgctttg atgcccacct ggcccaggca gaaaacttac aagctctgtt tgtggctctg
     2221 aatgaccagg tctttgagat ccgcgagctg gccatctgca ctgtgggccg actaagcagc
     2281 atgaacccag ccttcgtcat gcctttcctg cgcaagatgc tcatccagat cctgacagag
     2341 ctggagcaca gcggcattgg gagaatcaag gagcagagcg cccgcatgct ggggcacctg
     2401 gtgtccaacg ccccccggct catccgcccc tacatggagc ctatcctgaa ggctttaatt
     2461 ttgaaactga aagatccaga ccctgaccca aacccgggcg tgatcaataa cgtgttggcc
     2521 actataggag aactggctca ggtgagcggc ctggaaatgc ggaagtgggt ggacgagctc
     2581 tttatcatca tcatggacat gctgcaggac tcctccctgc tggccaaaag gcaggtggct
     2641 ttgtggaccc tgggacagtt ggtggccagc actggctatg tggtggagcc ctacaggaag
     2701 taccccactt tgcttgaagt gctgctgaat ttcctgaaga cggagcagaa ccagggcact
     2761 cggagagagg ctatccgagt gttggggctc cttggggctt tggatcccta caagcacaaa
     2821 gtgaacatcg gcatgatcga ccagtcccgg gacgcttccg ctgtcagcct gtcagagtcc
     2881 aagtcaagtc aggattcctc tgactacagc accagtgaaa tgctggtcaa catgggaaac
     2941 ctgcccctgg acgagttcta ccccgctgtg tccatggtgg ccttgatgcg gatcttccga
     3001 gatcaatccc tctctcacca ccacaccatg gtggtgcagg ccatcacctt catcttcaag
     3061 tccctggggc tcaagtgtgt gcagttcctg ccccaggtca tgcccacatt ccttaatgtc
     3121 atccgagtct gtgatggggc catccgggaa tttctgttcc agcagctggg gatgctggtg
     3181 tcctttgtga agagccacat ccgtccctac atggatgaaa tagtcactct catgagagag
     3241 ttttgggtca tgaacacgtc aatccagagc acaatcattc ttctcattga gcagattgtg
     3301 gtggctctcg gaggggaatt taagctttat ctgccccagt tgatcccaca catgctgcgg
     3361 gtcttcatgc atgacaacag ccaaggccga atcgtctcca tcaagctgtt agccgcgatc
     3421 cagctgtttg gcgccaacct ggatgactat ctgcacttgt tgttgcctcc gattgtgaaa
     3481 ttgtttgatg cccctgaagt cccgctgcca tcaagaaagg cagcgctgga gacggtggac
     3541 cgcctgacag agtccctaga cttcactgac tacgcctccc gcatcattca cccaatagtt
     3601 cgtacgctag accagagccc agagctgcgc tccacagcca tggacactct gtcttcgctt
     3661 gtctttcaac tggggaagaa gtaccagatc ttcattccaa tggtgaataa agtcctcgtg
     3721 cgacaccgga tcaaccacca gcgctatgat gtgcttatct gcagaatcgt caaggggtac
     3781 acacttgctg atgaggaaga agaccctttg atttaccagc atcgaatgct aaggagcagc
     3841 cagggagatg ccctggccag tggaccagtt gagacaggac ccatgaagaa actgcatgtc
     3901 agcaccatca acctccaaaa ggcctgggga gctgccagaa gggtctccaa ggacgactgg
     3961 ctggagtggc tgaggcgctt gagtctggag cttctgaagg actcctcatc gccctccctg
     4021 cgctcatgct gggccctggc gcaggcctac aaccccatgg ccagggatct cttcaatgct
     4081 gcctttgtgt cctgctggtc tgagctgaat gaagaccagc aagatgagct catcaggagt
     4141 attgagttgg ctctcacttc tcaagacatt gctgaagtca cacaaaccct cctgaacttg
     4201 gctgagttca tggaacacag tgacaagggc cccctgccgc tgagagatga caatggcatc
     4261 gtgctcctgg gtgagagagc tgccaagtgc cgggcatatg ccaaagcact gcactacaaa
     4321 gaactggagt tccagaaagg gcccacgcct gccatacttg agtccctcat cagcattaac
     4381 aacaagctcc agcagcctga ggcagcttct ggggtgttgg aatacgccat gaaacacttc
     4441 ggagagctgg agatccaggc cacctggtat gagaagctgc atgagtggga ggatgctctc
     4501 gtggcctacg acaagaagat ggacacaaac aaggaagacc cggagctgat gctgggccga
     4561 atgcgctgcc tcgaggcctt gggggaatgg ggccagcttc atcagcagtg ctgtgaaaag
     4621 tggactctgg ttaatgatga gacccaggct aagatggccc ggatggctgc tgctgcagcg
     4681 tggggtttag gtcagtggga cagcatggag gagtacacct gcatgatccc acgggacacc
     4741 cacgatggag ccttttacag ggcagtgttg gctctacatc aggatctctt ctccttggcc
     4801 cagcagtgca ttgacaaggc cagggacctg ctggatgcag agctgactgc catggcagga
     4861 gagagctaca gccgagccta tggggccatg gtttcttgcc acatgctgtc cgagctggaa
     4921 gaggttatcc agtacaaact tgtccctgag cgtcgggaga tcatccggca gatctggtgg
     4981 gagagactgc agggctgcca gcgtattgtt gaggactggc agaaaatcct catggtccgg
     5041 tcccttgtgg tcagccctca tgaggacatg agaacctggc tcaagtacgc aagcctgtgt
     5101 ggcaagagtg gcagactggc tcttgctcat aaaaccttag tgttgctctt gggagttgat
     5161 ccatctcggc aacttgacca tcctctgcca accgctcacc ctcaagtgac ctatgcctac
     5221 atgaagaaca tgtggaaaag tgctcggaag attgacgcct tccagcacat gcaacacttt
     5281 gtgcagacca tgcagcagca ggcccagcat gccatcgcca cagaggacca gcagcacaag
     5341 caggagctgc ataagctcat ggccaggtgt tttctgaaac ttggggagtg gcagctgaac
     5401 ctccagggca tcaacgagag caccatcccc aaggtgctac agtactacag tgccgccaca
     5461 gagcatgacc gcagctggta caaggcttgg catgcatggg cagtgatgaa cttcgaagca
     5521 gtgctacact acaaacatca gaaccaagcc cgtgatgaga agaagaagct gcgtcatgcc
     5581 agcggggcca acatcaccaa tgccaccact gcagccacca ctgcagcctc tgctgctgct
     5641 gccaccagca cagagggcag caacagtgag agtgaagctg agagcaatga gaacagcccc
     5701 accccgtccc ctctgcagaa gaaggtcact gaggatttat ccaaaactct cttgttgtac
     5761 actgtccctg ctgttcaagg cttcttccgt tctatctcct tgtcaagagg caacaacctc
     5821 caggatacac taagagtcct caccctgtgg tttgattatg gtcactggcc agatgtcaat
     5881 gaagccttgg tggaaggggt gaaggccata cagattgaca cttggttaca ggttatacct
     5941 cagctcattg caagaattga cacacccaga cccttggtgg gccggctcat tcaccagctt
     6001 ctcacagata ttggtcggta ccacccacag gccctcatct accccctgac ggtggcttct
     6061 aagtctacca ccacagcccg tcacaatgca gccaacaaga tcttgaagaa catgtgtgaa
     6121 cacagcaaca cgctggtcca gcaggccatg atggtgagtg aagagctgat tcgggtagcc
     6181 atcctctggc atgagatgtg gcatgaaggc ctggaagagg catctcgctt gtactttggg
     6241 gagaggaacg tgaaaggcat gtttgaggtg ctggagcccc tgcatgctat gatggaacgg
     6301 ggtccccaga ctctgaagga aacatccttt aatcaggcat atggccgaga tttaatggag
     6361 gcacaagaat ggtgtcgaaa gtacatgaag tcggggaacg tcaaggacct cacgcaagcc
     6421 tgggacctct actatcacgt gttcagacgg atctcaaagc agctacccca gctcacatcc
     6481 ctggagctgc agtatgtgtc ccccaaactt ctgatgtgcc gagaccttga gttggctgtg
     6541 ccaggaacat acgaccccaa ccagccaatc attcgcattc aatccatagc cccgtctttg
     6601 caagtcatca catccaagca gaggcctcgg aagctgactc tgatgggcag caatgggcat
     6661 gagtttgttt tcctcctgaa aggccatgaa gatctgcggc aggatgaacg agtgatgcag
     6721 ctctttggcc tggtgaacac actcctagcc aatgacccca cttctcttcg caagaacctc
     6781 agcatccaga gatacgctgt catccctctg tccaccaact cgggcctcat tggctgggtg
     6841 ccccactgtg acacactgca tgccctcatc cgggactaca gagagaagaa gaagatcctg
     6901 ttgaacatcg agcatcgcat catgctgcgg atggctcctg actatgacca cctgacgttg
     6961 atgcagaagg tagaggtgtt tgagcatgct gtcaacaaca cagctgggga cgacctggcc
     7021 aagctactgt ggctaaaaag ccccagctcg gaggtgtggt ttgaccgaag aaccaactat
     7081 acccgctccc tggccgttat gtcgatggtc ggatacattt taggccttgg agacaggcac
     7141 ccatccaatc tgatgctgga ccggctgagt gggaagatcc tgcacattga ctttggggac
     7201 tgctttgagg tcgctatgac cagagagaaa tttccagaaa agattccatt tagactaaca
     7261 agaatgttga ccaatgctat ggaggttacg ggtctggatg gcaactacag aaccacatgc
     7321 cacaccgtga tggaagtgct ccgggaacac aaggacagtg tcatggctgt gctggaagcc
     7381 tttgtctatg acccactgct caactggagg ctgatggaca caaataccaa aggcaataag
     7441 cggtcccgga caaggacaga ctcctactct gccggccagt cagtagaaat tttggacggt
     7501 gtagaacttg gagaaccagc ccataagaaa gcagggacca ctgtgccaga atccatccat
     7561 tcattcattg gagacggttt ggtgaaacca gaagccttaa acaagaaagc tattcagatt
     7621 attaacaggg ttcgagataa gctcactggt cgggatttct ctcatgatga cactttggat
     7681 gttccaaccc aagtggagct gcttatcaag caggcaacat ctcacgagaa cctctgccag
     7741 tgctacattg gctggtgtcc cttctggtaa ctgaggcctg gaaaaccacg tcgtctcctc
     7801 ccaggcttta gtaccttgtc tgtgcttcca gtggactaaa accatggaca gacagttgga
     7861 cttgttaaat attttgaaat gtatatgaaa agaactactg tatattcaaa gttggcttcc
     7921 gccaacctcc tagctgctgt tgaaaagaca ctgtcagaaa cacaaggctt gattcagttc
     7981 ccaggacagt gaaacacagt aatccttcag aagccaagcc ttggattttg ggagaacaga
     8041 agatgggtaa ctgagaaata cgggttttga cttaacttac aagaaaactc atcataaaca
     8101 ttgctgacag aataatccag ttggtcctct caaccagggg ctccaacggc aaggacacag
     8161 aggtcggcac tccactatcc tgttacctca cccgtccctg gatgcagtgg cgacatttgc
     8221 aggatgggcc aacatggcta agagagtctg tcttccgcct gaccccacga tgctgaaact
     8281 cacaagacct gcccttccag gaggacattt gttcagaagc ctggccaccg ggcatgagca
     8341 ggtgtgccaa ggatctccat gcggggccac actggctcta ctgtgttcag tgagggaggg
     8401 atatgctgta tttgcagcag ggactcagaa cataaatgct gatcacagag ggacacacta
     8461 gagcaggttg tgagttataa gcaaagtaaa tatccaacta aatacacaaa gtataaagta
     8521 aagccacatc tagacaccac gttgtatctg agtaaatttt gtgccaataa atgacatcag
     8581 aattttaaaa gcataaaaaa aaaaaaaaaa aa
//
