LOCUS       NM_028832               1577 bp    mRNA    linear   ROD 31-MAY-2024
DEFINITION  Mus musculus mitochondrial transcription termination factor 2
            (Mterf2), transcript variant 4, mRNA; nuclear gene for
            mitochondrial product.
ACCESSION   NM_028832 XM_286264
VERSION     NM_028832.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1577)
  AUTHORS   Pellegrini,M., Asin-Cayuela,J., Erdjument-Bromage,H., Tempst,P.,
            Larsson,N.G. and Gustafsson,C.M.
  TITLE     MTERF2 is a nucleoid component in mammalian mitochondria
  JOURNAL   Biochim Biophys Acta 1787 (5), 296-302 (2009)
   PUBMED   19366608
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122238.4, AK047778.1 and AA285696.1.
            
            On Apr 30, 2010 this sequence version replaced NM_028832.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC046619.1, AK047778.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139, SAMN01164143
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG   :: upstream AUG and CDS
                                                  extension is not conserved
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                AC122238.4         177753-177778       c
            27-1564             AK047778.1         3-1540
            1565-1577           AA285696.1         263-275
FEATURES             Location/Qualifiers
     source          1..1577
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 41.63 cM"
     gene            1..1577
                     /gene="Mterf2"
                     /gene_synonym="1700007D05Rik; Mterfd3"
                     /note="mitochondrial transcription termination factor 2"
                     /db_xref="GeneID:74238"
                     /db_xref="MGI:MGI:1921488"
     exon            1..66
                     /gene="Mterf2"
                     /gene_synonym="1700007D05Rik; Mterfd3"
                     /inference="alignment:Splign:2.1.0"
     exon            67..185
                     /gene="Mterf2"
                     /gene_synonym="1700007D05Rik; Mterfd3"
                     /inference="alignment:Splign:2.1.0"
     exon            186..1567
                     /gene="Mterf2"
                     /gene_synonym="1700007D05Rik; Mterfd3"
                     /inference="alignment:Splign:2.1.0"
     CDS             242..1399
                     /gene="Mterf2"
                     /gene_synonym="1700007D05Rik; Mterfd3"
                     /note="mTERF domain-containing protein 3, mitochondrial;
                     MTERF domain containing 3; transcription termination
                     factor 2, mitochondrial"
                     /codon_start=1
                     /product="transcription termination factor 2,
                     mitochondrial precursor"
                     /protein_id="NP_083108.1"
                     /db_xref="CCDS:CCDS24088.1"
                     /db_xref="GeneID:74238"
                     /db_xref="MGI:MGI:1921488"
                     /translation="MPWRLPTGHQLCRLCLLRKPRPALKIKPSSACVTYGTDSQSDKE
                     NKRTVEKLSACSVDIRKIRRLKGWVLLEEETYVEEIANILKELGANKTVIASILERCP
                     EAIICSPAAVNTKRKLWQMVCKNEAELVQLIEQFPESFFTVKNQENQKLNVQFFQELG
                     LRNVVISRFLTTASSIFHNPVENNKQMIGVLQESYLNLGGSEANAKVWLLKLLSQNPF
                     IVLHSPRAVGETLKCLQGQGFTDSEVLQLLSKLKGFLFQLQPGSIQNSISFTKTTFEC
                     TDYDLRQLVVKCPALLCYPASVLEERIQALLKEGISIAQIRESPMVLELTPQIIQYRI
                     RKLNSLGYGIKDGHLASLNGTKKEFEANFSKMQAKQGRPLFNPVASLKVEE"
     regulatory      1540..1545
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mterf2"
                     /gene_synonym="1700007D05Rik; Mterfd3"
                     /note="hexamer: AATAAA"
     polyA_site      1559
                     /gene="Mterf2"
                     /gene_synonym="1700007D05Rik; Mterfd3"
                     /note="major polyA site"
ORIGIN      
        1 ggaacagggt gggaacttag ctcaacgccc aaggtctctc cgctgtgctt ggactgctgc
       61 ccacagtgcc actgaggtct attgcagaga ggtgacagaa tcacatttta gaagctacag
      121 aggagtccta aatggactga ctgaagccct ggagaaggac aaaatcgctc aggagagact
      181 ataaggtaca atgtggacat tctcagcctt aagatgtgga aatttagcca gagctcacag
      241 catgccgtgg aggttgccga caggacacca actctgcaga ctgtgtcttc tcagaaagcc
      301 gcgaccagct ctgaaaatca aaccctcttc agcttgtgtc acctacggaa cggacagcca
      361 gtcagataaa gaaaacaaga gaacggtgga aaagctcagt gcatgttcag ttgacattag
      421 aaaaatccgc aggctgaaag gatgggtgct tctagaggaa gaaacctacg ttgaagagat
      481 tgcaaatatt ttgaaagaac taggtgccaa taaaactgtg attgccagta tattagaacg
      541 ctgtccggaa gcgattatct gcagtcccgc tgctgttaac accaaaagga aactctggca
      601 gatggtctgc aaaaacgagg cagagttagt gcagttaata gagcagtttc cagaatcttt
      661 ctttactgtc aagaaccagg agaaccagaa gctaaatgtt cagttctttc aagagctggg
      721 actcagaaat gtggtgatta gcaggtttct gacaacggcc tctagcattt tccataatcc
      781 tgtagagaac aataaacaaa tgataggggt tctccaggag agctacctaa acttaggtgg
      841 atctgaggcc aatgctaaag tgtggctact aaaattatta agccaaaatc ccttcattgt
      901 gttacattct cctagagctg taggtgaaac gctgaaatgt cttcaagggc aaggcttcac
      961 agactctgaa gttcttcagc ttctgtccaa acttaaaggg tttcttttcc aacttcagcc
     1021 aggaagtatc cagaacagta tttccttcac taagactact tttgagtgta cagactatga
     1081 cctacgacag ttagttgtga aatgcccagc ccttctatgt tatcctgctt ctgtcctaga
     1141 agagagaatc caggcactgc tgaaagaagg catctccata gctcaaataa gagagtcacc
     1201 aatggttctg gaattgacgc cacagataat tcaatatagg ataagaaagc tgaattcttt
     1261 aggctacgga ataaaggatg gacatctagc aagtctaaat ggaacaaaaa aggagtttga
     1321 ggctaacttt agcaaaatgc aagccaaaca aggaaggcca ttatttaacc ctgtggcatc
     1381 attaaaggtt gaagagtgac aggacaaagt gacttaagca attcagctta taagcactaa
     1441 ggattctcag gacctactga gattgagttg tgttcaagtt acctcttaat tggtagtttc
     1501 tgactcattt gctgtatttt aaaatgtaaa ctgtgcttaa ataaaaccag taactttaat
     1561 cttggaaaaa aaaaaaa
//
