LOCUS       NP_083108                385 aa            linear   ROD 27-APR-2025
DEFINITION  transcription termination factor 2, mitochondrial precursor [Mus
            musculus].
ACCESSION   NP_083108 XP_286264
VERSION     NP_083108.1
DBSOURCE    REFSEQ: accession NM_028832.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 385)
  AUTHORS   Pellegrini,M., Asin-Cayuela,J., Erdjument-Bromage,H., Tempst,P.,
            Larsson,N.G. and Gustafsson,C.M.
  TITLE     MTERF2 is a nucleoid component in mammalian mitochondria
  JOURNAL   Biochim Biophys Acta 1787 (5), 296-302 (2009)
   PUBMED   19366608
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122238.4, AK047778.1 and AA285696.1.
            
            On Aug 30, 2004 this sequence version replaced XP_286264.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC046619.1, AK047778.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139, SAMN01164143
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG   :: upstream AUG and CDS
                                                  extension is not conserved
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..385
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 41.63 cM"
     Protein         1..385
                     /product="transcription termination factor 2,
                     mitochondrial precursor"
                     /note="mTERF domain-containing protein 3, mitochondrial;
                     MTERF domain containing 3; transcription termination
                     factor 2, mitochondrial"
                     /calculated_mol_wt=39436
     transit_peptide 1..35
                     /note="Mitochondrion.
                     /evidence=ECO:0000250|UniProtKB:Q49AM1; propagated from
                     UniProtKB/Swiss-Prot (Q8BKY8.1)"
                     /calculated_mol_wt=4035
     Region          <3..>24
                     /region_name="RING_Ubox"
                     /note="RING finger (Really Interesting New Gene) domain
                     and U-box domain superfamily; cl17238"
                     /db_xref="CDD:473075"
     mat_peptide     36..385
                     /product="Transcription termination factor 2,
                     mitochondrial. /id=PRO_0000255465"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BKY8.1)"
                     /calculated_mol_wt=39436
     Region          58..360
                     /region_name="mTERF"
                     /note="pfam02536"
                     /db_xref="CDD:460581"
     CDS             1..385
                     /gene="Mterf2"
                     /gene_synonym="1700007D05Rik; Mterfd3"
                     /coded_by="NM_028832.3:242..1399"
                     /db_xref="CCDS:CCDS24088.1"
                     /db_xref="GeneID:74238"
                     /db_xref="MGI:MGI:1921488"
ORIGIN      
        1 mpwrlptghq lcrlcllrkp rpalkikpss acvtygtdsq sdkenkrtve klsacsvdir
       61 kirrlkgwvl leeetyveei anilkelgan ktviasiler cpeaiicspa avntkrklwq
      121 mvckneaelv qlieqfpesf ftvknqenqk lnvqffqelg lrnvvisrfl ttassifhnp
      181 vennkqmigv lqesylnlgg seanakvwll kllsqnpfiv lhspravget lkclqgqgft
      241 dsevlqllsk lkgflfqlqp gsiqnsisft kttfectdyd lrqlvvkcpa llcypasvle
      301 eriqallkeg isiaqiresp mvleltpqii qyrirklnsl gygikdghla slngtkkefe
      361 anfskmqakq grplfnpvas lkvee
//
