LOCUS       NM_172963               7238 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus microtubule crosslinking factor 1 (Mtcl1), transcript
            variant 2, mRNA.
ACCESSION   NM_172963 XM_355026
VERSION     NM_172963.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7238)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7238)
  AUTHORS   Satake,T., Yamashita,K., Hayashi,K., Miyatake,S., Tamura-Nakano,M.,
            Doi,H., Furuta,Y., Shioi,G., Miura,E., Takeo,Y.H., Yoshida,K.,
            Yahikozawa,H., Matsumoto,N., Yuzaki,M. and Suzuki,A.
  TITLE     MTCL1 plays an essential role in maintaining Purkinje neuron axon
            initial segment
  JOURNAL   EMBO J 36 (9), 1227-1242 (2017)
   PUBMED   28283581
  REMARK    GeneRIF: These results indicate that MTCL1-mediated formation of
            stable microtubule bundles is crucial for maintenance of AnkG
            localization.
REFERENCE   3  (bases 1 to 7238)
  AUTHORS   Araujo,D.J., Anderson,A.G., Berto,S., Runnels,W., Harper,M.,
            Ammanuel,S., Rieger,M.A., Huang,H.C., Rajkovich,K., Loerwald,K.W.,
            Dekker,J.D., Tucker,H.O., Dougherty,J.D., Gibson,J.R. and
            Konopka,G.
  TITLE     FoxP1 orchestration of ASD-relevant signaling pathways in the
            striatum
  JOURNAL   Genes Dev 29 (20), 2081-2096 (2015)
   PUBMED   26494785
REFERENCE   4  (bases 1 to 7238)
  AUTHORS   Sato,Y., Akitsu,M., Amano,Y., Yamashita,K., Ide,M., Shimada,K.,
            Yamashita,A., Hirano,H., Arakawa,N., Maki,T., Hayashi,I., Ohno,S.
            and Suzuki,A.
  TITLE     The novel PAR-1-binding protein MTCL1 has crucial roles in
            organizing microtubules in polarizing epithelial cells
  JOURNAL   J Cell Sci 126 (Pt 20), 4671-4683 (2013)
   PUBMED   23902687
REFERENCE   5  (bases 1 to 7238)
  AUTHORS   Nishimura,M., Yokoi,N., Miki,T., Horikawa,Y., Yoshioka,H.,
            Takeda,J., Ohara,O. and Seino,S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
REFERENCE   6  (bases 1 to 7238)
  AUTHORS   Sousa-Nunes,R., Rana,A.A., Kettleborough,R., Brickman,J.M.,
            Clements,M., Forrest,A., Grimmond,S., Avner,P., Smith,J.C.,
            Dunwoodie,S.L. and Beddington,R.S.
  TITLE     Characterizing embryonic gene expression patterns in the mouse
            using nonredundant sequence-based selection
  JOURNAL   Genome Res 13 (12), 2609-2620 (2003)
   PUBMED   14613977
REFERENCE   7  (bases 1 to 7238)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   8  (bases 1 to 7238)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK147205.1 and BP760436.1.
            
            On Jan 30, 2008 this sequence version replaced NM_172963.3.
            
            Transcript Variant: This variant (2) lacks an exon in the 3'
            region, which results in a downstream translation termination
            codon, compared to variant 1. The resulting isoform (2) is longer
            and has a distinct C-terminus, compared to isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147205.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-7217              AK147205.1         3-7219
            7218-7238           BP760436.1         27-47               c
FEATURES             Location/Qualifiers
     source          1..7238
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 35.3 cM"
     gene            1..7238
                     /gene="Mtcl1"
                     /gene_synonym="1110012J17Rik; Ccdc165; D130071O13;
                     Kiaa0802; mKIAA0802; Soga2; t8219b25"
                     /note="microtubule crosslinking factor 1"
                     /db_xref="GeneID:68617"
                     /db_xref="MGI:MGI:1915867"
     exon            1..1434
                     /gene="Mtcl1"
                     /gene_synonym="1110012J17Rik; Ccdc165; D130071O13;
                     Kiaa0802; mKIAA0802; Soga2; t8219b25"
                     /inference="alignment:Splign:2.1.0"
     CDS             406..6243
                     /gene="Mtcl1"
                     /gene_synonym="1110012J17Rik; Ccdc165; D130071O13;
                     Kiaa0802; mKIAA0802; Soga2; t8219b25"
                     /note="isoform 2 is encoded by transcript variant 2;
                     coiled-coil domain-containing protein 165; protein SOGA2;
                     SOGA family member 2; PAR-1-interacting protein;
                     microtubule cross-linking factor 1"
                     /codon_start=1
                     /product="microtubule cross-linking factor 1 isoform 2"
                     /protein_id="NP_766551.3"
                     /db_xref="CCDS:CCDS28946.2"
                     /db_xref="GeneID:68617"
                     /db_xref="MGI:MGI:1915867"
                     /translation="METLNGPAGGGAPDTKPQPAGQHHRHHHLHPLAERRRLHRAPSP
                     ARPFLKDLHTRPATATPSAGRAPTPAAPRSPSLAGKAPPSPGPPAAPGRLSRRSGVVP
                     GAKDKPPPGAGARSAGGAKAVPGTRRAARAGPAEPLSRVGRPTGAEPPPAVAKGRKTK
                     RGPGTPPARAVVPPARASRVPAVTLSVTSVAGCRINHTDSSSDLSDCASEPLSDEQRL
                     LPAASSDAESGTGSSDREPIRGAPTPSSGSRGPPPGSPEPPILLAAPPVASACLGGRS
                     SPGGASTGSPGPGSQEDVGGRAPPERTILGTSKEPSLGEQPRLLVVAEEEELLREMEE
                     LRSENDYLKDELDELRAEMEEMRDSYLEEDGYQLQELRRELDRANKNCRILQYRLRKA
                     EQKSLKVAETGQVDGELIRSLEQDLKVAKDVSVRLHHELETVEEKRAKAEDDNETLRQ
                     QMIEVEVSRQALQNEVERLRESSLKRRGSREMYKEKKLVNQDDSADLKCQLQFVKEEA
                     SLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPPSTREAELKLRLKLV
                     EEEASILGRKIVELEVENRGLKAEMEDIRVQHEREGTGRDHVPSTPTSPFGDSMESST
                     ELRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFKFEPHQESGWLGDGVSKGPAA
                     SVPLQEELKSARLQIDELSGKVLKLQCENRLLLSNAQRGDLAAHLGLRAPSPRDSDAE
                     SDAGKKESDGEEGRLPQPKREGPVGGESDSEDMFEKTSGFGSGKPSEASEPCPAELLR
                     VREDTECLVTIKLEAQRLERTVERLISDTDGFIHDSGLRGNGLASPGVQGGGGEGNSP
                     SEPHLLETINVRMKAFRKELQAFLEQMSRIVDGLSPLSHLTESSSFLSTVTSVSRDSP
                     IGTLGKELGPDLQSKLREQLEWQLNQDRGDEREGLRLRATRELHRRADGDSGSHHGLG
                     GQSCFNLEMEEDHLYALRWKELEMHSLALQNTLHKRTWSDEKNLLQQELRSLKQNIFL
                     FYVKLRWLLKHWRQGKQMEEGGEDLEESEHPENVPGLAELGVQGVHQTDGIDQEDADQ
                     GCSLPMGEHAPHSLVQISEHGSRLQSSDGGPLNKQVVENQQLFRALKALLEDFRSELR
                     EDEHARLRLQQQYASDKAAWDVEWAVLKCRLEQLEEKTEKSLGELDSSAEGKGALKKE
                     REVHQKLLADSHSLVMDLRWQIHHREKNWNREKVELLERLDSERQEWGRQKEELLWRV
                     EQLQKEKSPRRSGSFLCSRREDDTRPYPHQGSLHSSRPVSMWPCEDADSIPFEDRPLS
                     KLKESDRCSASENLYLDALSLDDDPGDPPPLRNCLAEEEESRKGNLQRAVSVSCMSEF
                     QRLMDVSPFLPEKGLPSAGSKEDVTPPLSPDDLKYIEEFHSNDWDYASPRAEADRPPD
                     PWADRTEMGRVGHEATTEPCPDPSWYLTTSVTMTTDTMTSPEHCQKQPLRTHVLTEQS
                     GVHVLHSPPAIRRVDSIASGGEGRSRADPEGPFPMSRARGNLADAKGGHPEPVLNRWP
                     CTPPRHPRDCVEGSLRPLDRPICPSLGFASPLNSLDMSKNMSDDMKEVAFSVRNAICA
                     GPAEPHVRDMACQTNGSRTAGTQTIQTISVGLQTEALRASGVTSSPHKCLTPKAGGGT
                     TPVSSPSRSLRSRQVAPAIEKVQAKFERTCCSPKYGSPKLQRKPLSKADQPNSRTSPG
                     IPQKGFSESAWARSTTTRESPVHTTINDGLSSLFNIIDHSPIGVRAGSRSRSAEPRQE
                     LGPGQETGTSSRGRSPSPLGVGSETFREEGGESTPVRQDLSAPPGYTLTENVARILNK
                     KLLEHALKEERKQASHGSSGLTSDSHTGEPVPAEPGSMEELPCSALAPSLEPCFSRPE
                     RPANRRLPSRWAPPSPTASQSQSPGHPMSMEEHGEEDPPEEKPHL"
     exon            1435..1659
                     /gene="Mtcl1"
                     /gene_synonym="1110012J17Rik; Ccdc165; D130071O13;
                     Kiaa0802; mKIAA0802; Soga2; t8219b25"
                     /inference="alignment:Splign:2.1.0"
     exon            1660..1818
                     /gene="Mtcl1"
                     /gene_synonym="1110012J17Rik; Ccdc165; D130071O13;
                     Kiaa0802; mKIAA0802; Soga2; t8219b25"
                     /inference="alignment:Splign:2.1.0"
     exon            1819..1878
                     /gene="Mtcl1"
                     /gene_synonym="1110012J17Rik; Ccdc165; D130071O13;
                     Kiaa0802; mKIAA0802; Soga2; t8219b25"
                     /inference="alignment:Splign:2.1.0"
     exon            1879..3186
                     /gene="Mtcl1"
                     /gene_synonym="1110012J17Rik; Ccdc165; D130071O13;
                     Kiaa0802; mKIAA0802; Soga2; t8219b25"
                     /inference="alignment:Splign:2.1.0"
     exon            3187..3345
                     /gene="Mtcl1"
                     /gene_synonym="1110012J17Rik; Ccdc165; D130071O13;
                     Kiaa0802; mKIAA0802; Soga2; t8219b25"
                     /inference="alignment:Splign:2.1.0"
     exon            3346..3576
                     /gene="Mtcl1"
                     /gene_synonym="1110012J17Rik; Ccdc165; D130071O13;
                     Kiaa0802; mKIAA0802; Soga2; t8219b25"
                     /inference="alignment:Splign:2.1.0"
     exon            3577..3774
                     /gene="Mtcl1"
                     /gene_synonym="1110012J17Rik; Ccdc165; D130071O13;
                     Kiaa0802; mKIAA0802; Soga2; t8219b25"
                     /inference="alignment:Splign:2.1.0"
     exon            3775..3942
                     /gene="Mtcl1"
                     /gene_synonym="1110012J17Rik; Ccdc165; D130071O13;
                     Kiaa0802; mKIAA0802; Soga2; t8219b25"
                     /inference="alignment:Splign:2.1.0"
     exon            3943..4197
                     /gene="Mtcl1"
                     /gene_synonym="1110012J17Rik; Ccdc165; D130071O13;
                     Kiaa0802; mKIAA0802; Soga2; t8219b25"
                     /inference="alignment:Splign:2.1.0"
     exon            4198..4476
                     /gene="Mtcl1"
                     /gene_synonym="1110012J17Rik; Ccdc165; D130071O13;
                     Kiaa0802; mKIAA0802; Soga2; t8219b25"
                     /inference="alignment:Splign:2.1.0"
     exon            4477..4508
                     /gene="Mtcl1"
                     /gene_synonym="1110012J17Rik; Ccdc165; D130071O13;
                     Kiaa0802; mKIAA0802; Soga2; t8219b25"
                     /inference="alignment:Splign:2.1.0"
     exon            4509..6048
                     /gene="Mtcl1"
                     /gene_synonym="1110012J17Rik; Ccdc165; D130071O13;
                     Kiaa0802; mKIAA0802; Soga2; t8219b25"
                     /inference="alignment:Splign:2.1.0"
     exon            6049..7221
                     /gene="Mtcl1"
                     /gene_synonym="1110012J17Rik; Ccdc165; D130071O13;
                     Kiaa0802; mKIAA0802; Soga2; t8219b25"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7196..7201
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mtcl1"
                     /gene_synonym="1110012J17Rik; Ccdc165; D130071O13;
                     Kiaa0802; mKIAA0802; Soga2; t8219b25"
                     /note="hexamer: AATAAA"
     polyA_site      7219
                     /gene="Mtcl1"
                     /gene_synonym="1110012J17Rik; Ccdc165; D130071O13;
                     Kiaa0802; mKIAA0802; Soga2; t8219b25"
                     /note="major polyA site"
ORIGIN      
        1 gcagcttctc tccgccggag cagccgagca gaagccgtgg ctgccgatcc cccgcggact
       61 ggcagtgggc ggggagcgga actcgggagc cgggcgcgcg tcgccagaca agtgtttttg
      121 tgcgaggccg cggtggcggc cacttcagct ctctgaacgc acggtgcagg ggatgcgagc
      181 ggccgtggcg gctgtgccag gaggatccga gcgccgttga cctgagcgag gggacacact
      241 cccccgggtc ggctgagtgc gggggagggg acggcgggag cgcagggtgc acgccgggcg
      301 gggcaggggg tcagtgatga ccgggcgcgc ggggaggctg cacgccgccg ccgccgcccg
      361 gagcatctgc cgcctgagct gcggatcgca gccgccgccc gggccatgga gacgctgaac
      421 ggccccgcgg gcggcggcgc cccggacacc aagccgcagc cagccggcca gcatcaccgc
      481 caccaccacc tgcacccgct ggccgagagg aggcggctgc accgcgcacc ctcgcccgcc
      541 agacccttcc tcaaggacct gcacacgcgg cccgccacgg ccaccccctc tgcgggccgt
      601 gccccgactc ccgcggctcc tcgctcgcct agccttgccg ggaaggcgcc gccgtcgccc
      661 gggcccccgg ccgcgcccgg tcgcctctcc cgacgcagcg gtgtagtccc cggcgcgaag
      721 gacaagccgc cgccgggcgc cggagccagg tcggcgggcg gcgctaaggc cgtcccgggg
      781 accaggaggg cggcgcgcgc ggggccggcg gagccactgt cccgggttgg gaggccgact
      841 ggggccgagc caccgcctgc cgtcgcgaag ggtcgcaaaa ccaagcgcgg ccccgggacg
      901 cctccagctc gcgccgtcgt gcccccggct cgcgcctccc gggtccccgc cgtgaccctc
      961 tctgtgacct cggtggctgg ctgtcgtatc aaccacacgg acagcagctc ggatctctcc
     1021 gactgcgcct ccgaaccctt gtctgatgag cagcgcctac tccccgccgc cagcagcgac
     1081 gctgagtcgg gcaccggctc cagtgaccgg gaacccatac gcggagcacc cactccgagc
     1141 tccggatccc gcgggccgcc gccgggcagc cccgagcccc ctatcctgct cgcggcgccc
     1201 cctgtcgcca gtgcctgtct cgggggccga agcagcccag gcggggcctc cacagggtcc
     1261 ccgggacccg gttctcagga ggatgttggg ggccgagcgc caccggagcg gacgattctg
     1321 gggacctcca aggagcctag cctgggcgaa cagccccggc tcttggtggt ggctgaggaa
     1381 gaggagttgc tgagggagat ggaggaactg cgctcggaga acgactacct caaggacgag
     1441 ctggatgagc tccgtgcaga gatggaggag atgagggata gctatctgga ggaggacggg
     1501 taccagctgc aggagctccg gagagagctg gaccgtgcta acaagaactg cagaatcctg
     1561 cagtaccgac tcaggaaagc cgagcagaag agcctgaaag tggcggaaac agggcaggtg
     1621 gacggggagc tcatcagaag cctggagcag gacttgaagg tagccaaaga tgtgtctgtc
     1681 agattacacc acgaactcga gaccgtggag gagaagcgcg ctaaggctga agacgacaac
     1741 gaaacgctcc ggcagcagat gatcgaggtg gaggtatcca gacaggccct ccagaatgag
     1801 gtggagagac tgagggagag ttctctgaag agaagaggca gtcgggaaat gtacaaagag
     1861 aagaaacttg ttaaccagga tgacagtgcg gatttgaagt gtcagcttca gtttgtcaaa
     1921 gaggaagctt ccctgatgcg caaaaagatg gccaagttgg ggcgggagaa ggacgagttg
     1981 gagcaggaac tgcagaagta taagtccctc tatggtgatg tggacagtcc cctcccaaca
     2041 ggggaggctg gtggtccccc cagcaccagg gaggcagagc tgaaactgcg gctgaagttg
     2101 gtggaggagg aagccagcat cttgggcagg aagatcgtgg agctggaggt ggaaaaccgt
     2161 ggcctcaaag cagagatgga agacatacgg gttcagcatg aacgcgaggg aacaggcagg
     2221 gaccacgtgc caagcactcc tacctcaccc ttcggagact caatggagtc ctccacggag
     2281 ctccgccggc acctgcagtt tgtggaagaa gaggctgagc tgctgaggag atccatctct
     2341 gagattgaag atcacaaccg gcagttgacc cacgagctga gcaagttcaa gtttgagcct
     2401 caccaggagt cagggtggct tggggacggt gtgtctaagg gccccgcggc cagcgttccc
     2461 ctgcaggagg agctgaagtc agccaggcta cagatcgatg agctgagcgg gaaggtactg
     2521 aagctgcagt gtgagaaccg gctgcttctg tccaatgccc aacggggtga cctcgccgca
     2581 catctggggc tgcgcgctcc tagcccccgg gacagtgatg ccgagagtga cgcgggcaag
     2641 aaagagagcg atggggagga gggccgcctt ccccagccaa agcgagaagg ccctgttggt
     2701 ggggagagcg actcggagga catgtttgag aagacctcgg gcttcggaag cggaaagccg
     2761 tcggaggcta gtgagccatg cccggcagag ctgctaaggg tccgggagga taccgagtgc
     2821 ctggtgacca taaagctgga ggctcagcgg cttgagcgga ctgtggagcg cctcatctct
     2881 gatacagatg gtttcatcca cgactcagga ctgcggggca atggattggc ctcacctgga
     2941 gtccaaggcg gaggaggtga gggcaacagc ccgagtgagc cccacttgtt ggagaccatc
     3001 aatgtgagga tgaaggcttt caggaaagag ctgcaggcct tcctggagca gatgtcccgg
     3061 attgtggatg gtctctcgcc cttatcccac ctcacagagt catccagctt cctctccact
     3121 gtgacttctg tgtcccggga ctcccccatc gggaccctgg gaaaggagtt gggcccagac
     3181 ttgcagtcca aactgagaga gcagctggaa tggcagctca atcaggatcg aggggacgag
     3241 cgagagggcc tgcgtctccg agccactcgg gagctgcacc ggcgcgcgga tggggattcc
     3301 gggagccacc atgggctggg aggccagagc tgtttcaacc tagagatgga ggaggaccac
     3361 ctctacgccc tgcggtggaa ggaactggag atgcacagcc tggccctgca gaacaccctt
     3421 cacaagcgga cgtggagcga cgagaagaat ctgctgcagc aggagctcag gtccctgaag
     3481 cagaacatct tcctcttcta cgtcaagctc aggtggctgc tgaaacactg gcgccaaggg
     3541 aagcagatgg aggagggagg agaggatctg gaggagagcg aacatccaga gaatgtgcct
     3601 gggcttgctg agcttggagt ccagggggtt caccagacag atgggataga ccaggaggat
     3661 gctgaccaag gctgtagcct tcccatggga gagcatgccc cacactccct ggtacagatc
     3721 agcgaacacg gatcacggct acagagttca gacgggggac cacttaacaa acaggtggtg
     3781 gaaaaccagc agctcttcag ggccctcaag gctctgctgg aggacttccg ttcggagctg
     3841 cgcgaagacg agcatgcgcg gctgcggctg cagcagcagt acgccagcga caaggctgcg
     3901 tgggatgtgg agtgggctgt gctcaagtgc cgcctggaac agctggaaga gaagactgag
     3961 aaaagcttgg gcgagctgga ctcctctgct gagggcaaag gggccttgaa gaaggagaga
     4021 gaggtgcacc agaaactgct ggctgacagc cacagcctgg tgatggacct gcgctggcag
     4081 atccatcacc gagagaagaa ctggaaccgg gagaaggtgg agctgctgga gcgtctggac
     4141 agcgagcggc aggagtgggg gcgacagaag gaggagctcc tgtggcgggt ggagcagtta
     4201 cagaaagaga aaagtccccg gagaagcggc agtttcctct gcagccgaag ggaagacgac
     4261 acacgccctt acccgcacca aggaagcctt cactcctcca gacctgtgtc catgtggccc
     4321 tgtgaagacg ccgactccat cccatttgaa gaccggccgc tctccaaact gaaggagtcg
     4381 gacaggtgct cggccagtga gaacctgtac ttggacgctt tgtccctgga tgatgatcca
     4441 ggggatccgc cacccctcag gaactgcctt gccgaggaag aagaaagtcg caagggcaat
     4501 cttcagaggg ctgtgtctgt gtcctgtatg tccgagttcc agcgtctgat ggacgtctct
     4561 ccgttcctgc ctgagaaggg gctaccttcc gccggcagca aggaggatgt cactccaccc
     4621 ttgtctcccg acgacttgaa atacattgaa gaattccata gcaacgactg ggattacgca
     4681 tcccccaggg ctgaggccga tcggcctcca gacccctggg cagacaggac cgagatgggg
     4741 agggtggggc atgaagccac cacagagcct tgtccggatc cctcctggta tctgaccaca
     4801 agtgtcacga tgacgacaga caccatgacc agtccggagc actgccagaa gcagccactg
     4861 cggacccatg tcctcactga gcagtctggt gtgcacgtgc tgcacagccc gcctgccatt
     4921 cgccgggttg acagtatagc atcaggcggc gagggcagga gccgagcgga ccccgagggc
     4981 ccctttccta tgagcagagc aagagggaac ctggcagatg ccaagggggg tcatccagaa
     5041 cctgtgctca acaggtggcc ttgcacgcca cccagacatc cccgggactg tgtggagggg
     5101 tctcttcgcc ccctcgacag acctatctgc ccctccctgg gatttgcctc ccctctgaac
     5161 agcctagata tgtctaagaa catgagtgat gacatgaagg aggtggcttt ttctgtcagg
     5221 aatgccatct gcgccggtcc tgccgagcca cacgtcaggg atatggcctg ccagaccaat
     5281 gggtccagga cagcagggac gcagaccatc cagacaatca gcgtgggcct gcagaccgag
     5341 gccctacgtg ccagcggcgt caccagcagc ccccacaagt gtctcacgcc aaaagccgga
     5401 ggtggcacca cacccgtgtc ttctccttcc cgcagcctta ggagtagaca ggtggcccct
     5461 gccattgaga aggtgcaggc caagtttgaa cgcacctgct gctccccaaa gtacggttct
     5521 cccaaacttc agagaaagcc cctctcaaaa gctgaccagc caaatagcag gacctcacca
     5581 ggcatacccc agaaagggtt cagcgagtca gcctgggccc gctccaccac cacgagggag
     5641 agccctgtgc acaccaccat caatgatggc ctctccagcc tcttcaatat catcgaccac
     5701 agtcccatcg gggtgcgggc tgggagccga tctcggtcag cagaacctcg acaggagctg
     5761 ggtccaggcc aggaaacggg caccagttcc agagggaggt cgcccagccc gctaggggta
     5821 ggctccgaga cgttcaggga ggagggagga gagagcacgc cagtgagaca ggacttatct
     5881 gcgccccctg gctacacgct cactgagaat gtggcccgga tcctcaacaa aaagttgttg
     5941 gagcatgcct taaaggagga gaggaagcaa gccagccatg gctcctcagg tctcaccagc
     6001 gacagccaca ctggagaacc agtgccagcc gagccaggat ccatggagga actgccttgt
     6061 tctgcgctcg cgccctccct agagccctgc ttttccaggc cagagagacc agcaaaccgc
     6121 cgccttccat cccgttgggc cccaccttcc cccactgcct cacagtcaca gtcacccgga
     6181 cacccgatgt ccatggagga acacggtgag gaggacccac cagaggagaa gccacacctg
     6241 tgacaggatg caagcttgcg tggatgatcg ccggaatagt tcactgtaat ttgcataacc
     6301 agaccatcac cgccatcagc caacctccat cccaaaggaa agatgtagat cctttctcaa
     6361 ggtcgaagga tgcttttaaa aacacacggc tactgaatgt tcaacctggt aaactgagat
     6421 gtttcgggaa tgaaacagta aacgtgcctg taatcatttt ttcatagctc agaaaactat
     6481 ttttgtctcc catctttttt acacatgata tattaaacaa aaaaggtaaa taaggtataa
     6541 atagatttaa agagttttaa aatgtacatt tgaagagatt ccgagcaccc ttgttctcag
     6601 ttctgcctgc ctgttgaatt tgcactgttc cgttctggtt gggtttctcc atgttgagtt
     6661 cggagtgttc taagttaaat tttattttgt ccagtcttaa tttttcagga gtctttctta
     6721 acgctttaga ctgtcttaac tcagtgaact ttttgtaatg ataaggccgt gaggccagaa
     6781 gacgagagtg tctgtcatct gaaaggatgc aggccaacct tgctgaaaag gtacggagcc
     6841 cttcagatag acttaagact ctgcgtgacc catctgccca gcctgaccgc acgtcctcgg
     6901 gcacctgtac atacactgct ctgtccctgc cctcacctgc gtgtgtgtca gtctggtcta
     6961 ctgtaacttg ttgtgaagtt ccttgtaccg tgtgtactgt tgctgttggt ctcttgtacc
     7021 agtaagacaa tggctccatt ttttttaatt attgttaaaa cattaactga tggtgtacaa
     7081 atctcacttg acatttttct tgtttaagga aaagcaccat aaaaaaaaaa ataaggaggc
     7141 caaaccgaga cagacaaagg tgcctcaggt ctgcctgaga ccacggtgac atggaaataa
     7201 agtccttaca agaaagcaac aaaaaaaaaa aaaaaaaa
//
