LOCUS       NM_144898               1825 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus misato 1, mitochondrial distribution and morphology
            regulator (Msto1), mRNA.
ACCESSION   NM_144898
VERSION     NM_144898.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1825)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY267786.1 and AK163280.1.
            
            On Jul 25, 2009 this sequence version replaced NM_144898.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK170160.1, AK166236.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-141               BY267786.1         2-142
            142-1825            AK163280.1         2-1685
FEATURES             Location/Qualifiers
     source          1..1825
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 39.01 cM"
     gene            1..1825
                     /gene="Msto1"
                     /gene_synonym="mst"
                     /note="misato 1, mitochondrial distribution and morphology
                     regulator"
                     /db_xref="GeneID:229524"
                     /db_xref="MGI:MGI:2385175"
     exon            1..158
                     /gene="Msto1"
                     /gene_synonym="mst"
                     /inference="alignment:Splign:2.1.0"
     CDS             75..1745
                     /gene="Msto1"
                     /gene_synonym="mst"
                     /note="misato homolog 1"
                     /codon_start=1
                     /product="protein misato homolog 1"
                     /protein_id="NP_659147.2"
                     /db_xref="CCDS:CCDS17485.1"
                     /db_xref="GeneID:229524"
                     /db_xref="MGI:MGI:2385175"
                     /translation="MAGGAREVLTLQLGHFAGFVGAHWWNQQDAALGRMAEDEESPGE
                     LCPDVLYRTGRTLHGQETYTPRLILMDLKGSLNTLKEEGNLYRDRQLEAAVAWQGKLS
                     THRDDAQPKNPNLQGLLSAEGVRSSDGAWRAKLIQNIQNGKENSIKVWSDFLRVHLHP
                     RSICVIHKYHHDGETGRLEAFGQGESVLKEPRYLEELEDRLHFYVEECDYLQGFQLLC
                     DLHDGFSGVGAKTAELLQDEYAGRGVLTWGLLPGPYSLGEPQKNIYRLLNTAFGLVHL
                     TGYSSFVCPLSLGGNLGLRPKPPVNFPSLHYDATLPFHCSAILATALDTVTVPYRLRS
                     SMVTMAHLADVLSFSGKKVVTAEAIIPFPLVRGQSLPDILTQLGEATPWTSLSACGDS
                     AGHRCFAQSVVLRGIDRASHTSKLNPGTPLPSALHACASGEEVLAQYLQQQHPRVLSS
                     SHLLLTPCKVAPPYPHFFSSFSQKGLAMDSTPKGAAVQSIPVFGALRSTSSLHRTLGD
                     LAEELSRLDLRRWASFMDAGVEQDDMEEMLHELHRLAQCYQEGDSLSN"
     exon            159..294
                     /gene="Msto1"
                     /gene_synonym="mst"
                     /inference="alignment:Splign:2.1.0"
     exon            295..364
                     /gene="Msto1"
                     /gene_synonym="mst"
                     /inference="alignment:Splign:2.1.0"
     exon            365..440
                     /gene="Msto1"
                     /gene_synonym="mst"
                     /inference="alignment:Splign:2.1.0"
     exon            441..504
                     /gene="Msto1"
                     /gene_synonym="mst"
                     /inference="alignment:Splign:2.1.0"
     exon            505..592
                     /gene="Msto1"
                     /gene_synonym="mst"
                     /inference="alignment:Splign:2.1.0"
     exon            593..710
                     /gene="Msto1"
                     /gene_synonym="mst"
                     /inference="alignment:Splign:2.1.0"
     exon            711..845
                     /gene="Msto1"
                     /gene_synonym="mst"
                     /inference="alignment:Splign:2.1.0"
     exon            846..998
                     /gene="Msto1"
                     /gene_synonym="mst"
                     /inference="alignment:Splign:2.1.0"
     exon            999..1130
                     /gene="Msto1"
                     /gene_synonym="mst"
                     /inference="alignment:Splign:2.1.0"
     exon            1131..1315
                     /gene="Msto1"
                     /gene_synonym="mst"
                     /inference="alignment:Splign:2.1.0"
     exon            1316..1420
                     /gene="Msto1"
                     /gene_synonym="mst"
                     /inference="alignment:Splign:2.1.0"
     exon            1421..1530
                     /gene="Msto1"
                     /gene_synonym="mst"
                     /inference="alignment:Splign:2.1.0"
     exon            1531..1825
                     /gene="Msto1"
                     /gene_synonym="mst"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1778..1783
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Msto1"
                     /gene_synonym="mst"
                     /note="hexamer: AATAAA"
     polyA_site      1799
                     /gene="Msto1"
                     /gene_synonym="mst"
                     /note="major polyA site"
ORIGIN      
        1 gtgctcgcgc gggagccgcc ccctccggct gatgggcccg cggcggcagt ggagtgccca
       61 agagcagcgg cggtatggcg ggcggggccc gcgaggtgct cacgctgcag ttgggacatt
      121 tcgcgggttt cgtgggggcg cactggtgga accagcagga tgctgcgctg ggacgcatgg
      181 ccgaggacga agagtcgcca ggcgagctgt gccccgacgt cttgtacaga acaggccgga
      241 cactgcatgg ccaggaaacc tatacgcctc gactcatcct aatggatctg aaaggtagtc
      301 tgaacactct aaaagaagaa ggtaacctct acagagaccg acagctagag gctgcagtag
      361 cgtggcaggg gaagctcagc acacacagag atgacgccca accaaagaac ccaaacctcc
      421 agggccttct gagtgcagag ggagtgcgga gtagtgacgg tgcctggagg gccaaactga
      481 ttcagaatat ccaaaatggc aaagagaaca gcatcaaagt ctggtcagac ttcctcagag
      541 tccatctcca tccacggagc atctgtgtga tccacaagta ccaccatgat ggggagacag
      601 gccggctgga ggcttttggc caaggggaga gtgtcctgaa ggagcccagg tacttggaag
      661 agctggagga cagactacac ttctatgtgg aggaatgtga ctacttgcag ggcttccagc
      721 tcctgtgtga cctgcacgat ggcttctctg gagtaggtgc taaaactgca gagctactac
      781 aagacgagta tgcagggcgg ggagtcctaa cctggggcct gctcccgggc ccctacagtc
      841 ttggggagcc tcagaaaaac atctatcgtc tcttaaacac ggcatttggt ctggtgcacc
      901 tgactggata cagctccttc gtctgtccct tatcccttgg agggaacctg ggcctgcgac
      961 ccaagccgcc tgtcaacttc ccttccctac attatgatgc cactctgccc ttccactgta
     1021 gcgccatcct ggcgacagcg ctggacacgg tgactgttcc ctatcgcctg cgctcctcaa
     1081 tggttaccat ggctcacttg gctgatgtgc taagtttctc tgggaaaaag gtggtgacag
     1141 cagaagcaat catccccttc ccactggttc gaggccagtc ccttcctgac atcctgacgc
     1201 agcttggaga agccacccca tggacctccc tgtcggcatg cggggattct gctggacatc
     1261 ggtgctttgc ccagtctgtg gtgctcagag gcatagacag agctagccac accagtaagc
     1321 tcaacccagg gacacctctg ccctctgctc tccacgcatg cgcctctgga gaagaagtct
     1381 tggcccagta cttacagcag cagcatccta gagtcttgag ttcgtcacat ctgctgctga
     1441 ctccctgcaa agtggctcct ccatacccac acttcttctc aagcttcagt cagaaagggc
     1501 tggccatgga cagtaccccc aagggcgcag cagtacagag catccctgtg tttggggcct
     1561 tgcgttcaac ttcatccttg caccgtacgc tgggagactt ggctgaagag ctcagcagac
     1621 ttgacctgcg gcgctgggct agcttcatgg acgctggcgt ggagcaggat gacatggaag
     1681 agatgctgca cgagttacac aggttggccc agtgttacca ggagggtgac agtctctcga
     1741 actgaagtcc aggggagggt agtgggagag aatttataat aaaagctgcc gtgcaggaac
     1801 ccagtgtgta gggacctgtt acatg
//
