LOCUS       NM_177822               2628 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus mesothelin-like (Mslnl), mRNA.
ACCESSION   NM_177822
VERSION     NM_177822.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2628)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2628)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC134908.5.
            
            On Mar 21, 2007 this sequence version replaced NM_177822.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK028891.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN01164133
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-262               AC134908.5         109975-110236
            263-363             AC134908.5         110798-110898
            364-484             AC134908.5         111720-111840
            485-605             AC134908.5         112884-113004
            606-691             AC134908.5         116592-116677
            692-818             AC134908.5         116859-116985
            819-1009            AC134908.5         117063-117253
            1010-1100           AC134908.5         117607-117697
            1101-1242           AC134908.5         117895-118036
            1243-1430           AC134908.5         118399-118586
            1431-1586           AC134908.5         118658-118813
            1587-1714           AC134908.5         118900-119027
            1715-1845           AC134908.5         119991-120121
            1846-1940           AC134908.5         120241-120335
            1941-2190           AC134908.5         120709-120958
            2191-2628           AC134908.5         121828-122265
FEATURES             Location/Qualifiers
     source          1..2628
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 12.84 cM"
     gene            1..2628
                     /gene="Mslnl"
                     /gene_synonym="4732467B22"
                     /note="mesothelin-like"
                     /db_xref="GeneID:328783"
                     /db_xref="MGI:MGI:3607710"
     exon            1..262
                     /gene="Mslnl"
                     /gene_synonym="4732467B22"
                     /inference="alignment:Splign:2.1.0"
     exon            263..363
                     /gene="Mslnl"
                     /gene_synonym="4732467B22"
                     /inference="alignment:Splign:2.1.0"
     CDS             321..2378
                     /gene="Mslnl"
                     /gene_synonym="4732467B22"
                     /note="mesothelin-like protein;
                     pre-pro-megakaryocyte-potentiating-factor-like"
                     /codon_start=1
                     /product="mesothelin-like protein precursor"
                     /protein_id="NP_808490.1"
                     /db_xref="CCDS:CCDS28525.1"
                     /db_xref="GeneID:328783"
                     /db_xref="MGI:MGI:3607710"
                     /translation="MSRTLRPSAMGSRVGALASPGLALLLSLTAHCSGPQAKGLPKGG
                     LNASEANTWVRNNTSLLQNFWCLPASQLPREQLSSLIRSLASQRVALKAWQLSCLANL
                     AAQLGLQDDFEFHPPNLLLFYDLSQVGDTNCRAFIHHAAQGDTELLTNLPNQRVALQR
                     TALACLGGPHLQLSASDLWLLGVLVCDMEAAQIVTADPSVLRNLLRCPRLTVMQTAAL
                     NTLLASGKTQIGPPGSWNLQGLQALGLLATYISPHLWEKVQEAVGLDFFRSVVAACRA
                     GQLSRHDARRFVDNFLESKATSVSSRPKRRTGRSCVRGNITAATLHDDLFLVHYDCTQ
                     LESCLGTRVLRANLDPLLQHPLPAECQRVVKAKLTQIYPHGIPEDQLHLIPSLVYLYS
                     LAEIGQWNITSGDTVMILLASDAALDNQTEAVLQRFLDHNGKVTGALLVAIGGSRLCW
                     MSLKQLQFIQPSEFRLAGAPDISPCPQSRKDALFVKAHEVFRNTSNVGEYYYLIRPYL
                     GGAPLEELQYLAQANISMDIDTFTNLNPLTLKSMGVDSVRNLLGQNLGDLRKARNHPN
                     VILWMHSHNMTDLSDMGLYTSPTQAYVANRPPNTAYPPSSLIHSLDPPGNDGVSHTSG
                     SPPVHLGYLSLAVALPSSLLWLLLCQLPSGQMATAHRTLGPMALAQGSWTPEHQIPEK
                     RSC"
     exon            364..484
                     /gene="Mslnl"
                     /gene_synonym="4732467B22"
                     /inference="alignment:Splign:2.1.0"
     exon            485..605
                     /gene="Mslnl"
                     /gene_synonym="4732467B22"
                     /inference="alignment:Splign:2.1.0"
     exon            606..691
                     /gene="Mslnl"
                     /gene_synonym="4732467B22"
                     /inference="alignment:Splign:2.1.0"
     exon            692..818
                     /gene="Mslnl"
                     /gene_synonym="4732467B22"
                     /inference="alignment:Splign:2.1.0"
     exon            819..1009
                     /gene="Mslnl"
                     /gene_synonym="4732467B22"
                     /inference="alignment:Splign:2.1.0"
     exon            1010..1100
                     /gene="Mslnl"
                     /gene_synonym="4732467B22"
                     /inference="alignment:Splign:2.1.0"
     exon            1101..1242
                     /gene="Mslnl"
                     /gene_synonym="4732467B22"
                     /inference="alignment:Splign:2.1.0"
     exon            1243..1430
                     /gene="Mslnl"
                     /gene_synonym="4732467B22"
                     /inference="alignment:Splign:2.1.0"
     exon            1431..1586
                     /gene="Mslnl"
                     /gene_synonym="4732467B22"
                     /inference="alignment:Splign:2.1.0"
     exon            1587..1714
                     /gene="Mslnl"
                     /gene_synonym="4732467B22"
                     /inference="alignment:Splign:2.1.0"
     exon            1715..1845
                     /gene="Mslnl"
                     /gene_synonym="4732467B22"
                     /inference="alignment:Splign:2.1.0"
     exon            1846..1940
                     /gene="Mslnl"
                     /gene_synonym="4732467B22"
                     /inference="alignment:Splign:2.1.0"
     exon            1941..2190
                     /gene="Mslnl"
                     /gene_synonym="4732467B22"
                     /inference="alignment:Splign:2.1.0"
     exon            2191..2628
                     /gene="Mslnl"
                     /gene_synonym="4732467B22"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcacagccac agtagattga ctaggcagag ccatcccggg ctgcttcctg ggccaggctt
       61 acagatgatc atgaaccgtg acagctttac ccacaccagc cctgcattct gggactcagc
      121 tgcaaggatc gacagaatct gagcctggac cgctggcatc cggaacacct gatctactat
      181 atcatgtggc catctggtca gaagtagcat cttccctgct ctggacagaa ccttcactac
      241 cagactccat attcctgctc agtcctggac ctacaaccca cagccttcgg gcttccctgc
      301 tttgagacat ttcagccagg atgagcagaa ctctccgacc gtcagctatg ggttccagag
      361 tgggtgccct ggcaagtcct ggtctcgccc tcctcctgtc cctcaccgcc cactgctcgg
      421 gtcctcaggc taaaggcttg cccaagggag gactgaatgc aagtgaagcc aacacatggg
      481 tcaggaacaa cacctccctc ctgcaaaact tctggtgctt gccagccagc cagctgcccc
      541 gagaacagct ctccagttta atcagaagcc tggcttcaca gagggttgca ctcaaagcct
      601 ggcagctcag ctgcttggcc aacctcgctg cacagctggg tctccaggat gacttcgaat
      661 tccacccacc caaccttcta cttttctacg atctgagcca ggtgggggac actaactgcc
      721 gggccttcat tcaccatgct gcccaagggg acacagaact gctcaccaac ttgcccaacc
      781 agagagttgc cctgcagcgc acagccttgg cctgtctggg cggaccccac ctacagctca
      841 gtgcttcaga cctgtggctt cttggggtcc tggtgtgtga catggaggca gcacaaattg
      901 tgactgcaga ccccagtgtg ctgaggaacc tgcttcgctg cccaaggctt actgtcatgc
      961 agactgcggc ccttaacacc ctgctggcca gtgggaagac gcaaatcggg cctcctggct
     1021 cctggaacct gcaggggcta caggccctcg gacttctggc cacttacatc agcccccacc
     1081 tgtgggagaa ggtgcaggag gctgtgggct tggacttctt ccgcagtgtg gtggctgctt
     1141 gccgggcagg ccaactgagc aggcacgatg ccagacgctt cgttgacaac ttcctagagt
     1201 ccaaggccac ttcagtgtcc tcaaggccca agcggcgcac agggagatcc tgtgtccgtg
     1261 gcaacatcac agcagccacc ctgcacgatg acctcttcct ggtgcactat gactgcaccc
     1321 agctggaatc ctgcctaggc acacgcgtgc tcagggccaa cctggacccc ttgctccaac
     1381 acccgctgcc tgcagagtgc cagcgcgttg tcaaagccaa gcttactcag atttacccac
     1441 atggcatccc tgaggaccag ctgcacctca tcccctcgct ggtctacctc tactccctcg
     1501 ctgaaatagg ccagtggaac atcacatccg gggacacagt gatgatcctg ctggcctcag
     1561 atgcggctct ggacaaccag acggaggcag ttctacagag gttcttggac cacaatggca
     1621 aggtcactgg agctcttctg gtggccatcg ggggttcccg tctctgctgg atgagcctca
     1681 agcagcttca gtttatccag ccctcagagt tccggctggc cggagctcca gacatctctc
     1741 cctgccccca gagtcggaag gatgcgctct ttgtcaaggc tcatgaggtc tttaggaaca
     1801 ccagtaatgt gggagaatat tactacttaa tccgccccta cctcggtggt gcccctttgg
     1861 aggaacttca atacctggca caggccaaca tctccatgga cattgacacg ttcaccaacc
     1921 tcaaccccct gacactgaag agcatgggag tggacagtgt gaggaatctg ctgggccaga
     1981 acctgggaga tctgcggaag gcccgcaacc acccaaatgt catcctgtgg atgcacagcc
     2041 acaacatgac agacctgtct gatatgggcc tatacaccag ccccacacag gcctatgtgg
     2101 ccaacaggcc ccccaacact gcctacccac catccagttt gatccactcc ttggatccgc
     2161 caggcaatga tggggtttcc cacacctcag gaagtcctcc agttcatctg gggtacctgt
     2221 cactcgctgt ggctctgcct tccagccttc tgtggctgct actgtgtcag ttaccttcgg
     2281 gacaaatggc cactgctcac aggacactag ggccaatggc actggcccag ggcagttgga
     2341 cccctgaaca tcagattcca gagaaacgga gctgctagat gggacaggac acctgcctag
     2401 gctgaagtac atgtccccag ccccagggga cctgctgcta tgtccccatc ctaggaggct
     2461 gtctctgact cccaggatct gagcccattc tgcccaacta aaaggacaaa ttggtaggag
     2521 gagacagagt ccagatcttc tggcctattc caagatagat gggactcggt gttacttgaa
     2581 tgtcacttgc cctcgatggc ggatctgaat aaagcacaag gccattgc
//
