LOCUS       NM_054043               6505 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus musashi RNA-binding protein 2 (Msi2), transcript
            variant 1, mRNA.
ACCESSION   NM_054043 XM_283029
VERSION     NM_054043.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6505)
  AUTHORS   Banik,J., Moreira,A.R.S., Lim,J., Tomlinson,S., Hardy,L.L.,
            Lagasse,A., Haney,A., Crimmins,M.R., Boehm,U., Odle,A.K.,
            MacNicol,M.C., Childs,G.V. and MacNicol,A.M.
  TITLE     The Musashi RNA binding proteins direct the translational
            activation of key pituitary mRNAs
  JOURNAL   Sci Rep 14 (1), 5918 (2024)
   PUBMED   38467682
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6505)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 6505)
  AUTHORS   Wang,R., Kato,F., Watson,R.Y., Beedle,A.M., Call,J.A., Tsunoda,Y.,
            Noda,T., Tsuchiya,T., Kashima,M., Hattori,A. and Ito,T.
  TITLE     The RNA-binding protein Msi2 regulates autophagy during myogenic
            differentiation
  JOURNAL   Life Sci Alliance 7 (5), e202302016 (2024)
   PUBMED   38373797
  REMARK    GeneRIF: The RNA-binding protein Msi2 regulates autophagy during
            myogenic differentiation.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6505)
  AUTHORS   Rajbhandari,N., Hamilton,M., Quintero,C.M., Ferguson,L.P., Fox,R.,
            Schurch,C.M., Wang,J., Nakamura,M., Lytle,N.K., McDermott,M.,
            Diaz,E., Pettit,H., Kritzik,M., Han,H., Cridebring,D., Wen,K.W.,
            Tsai,S., Goggins,M.G., Lowy,A.M., Wechsler-Reya,R.J., Von
            Hoff,D.D., Newman,A.M. and Reya,T.
  TITLE     Single-cell mapping identifies MSI+ cells as a common origin for
            diverse subtypes of pancreatic cancer
  JOURNAL   Cancer Cell 41 (11), 1989-2005 (2023)
   PUBMED   37802055
REFERENCE   5  (bases 1 to 6505)
  AUTHORS   Singh,S., Gaur,A., Sharma,R.K., Kumari,R., Prakash,S., Kumari,S.,
            Chaudhary,A.D., Prasun,P., Pant,P., Hunkler,H., Thum,T.,
            Jagavelu,K., Bharati,P., Hanif,K., Chitkara,P., Kumar,S., Mitra,K.
            and Gupta,S.K.
  TITLE     Musashi-2 causes cardiac hypertrophy and heart failure by inducing
            mitochondrial dysfunction through destabilizing Cluh and Smyd1 mRNA
  JOURNAL   Basic Res Cardiol 118 (1), 46 (2023)
   PUBMED   37923788
  REMARK    GeneRIF: Musashi-2 causes cardiac hypertrophy and heart failure by
            inducing mitochondrial dysfunction through destabilizing Cluh and
            Smyd1 mRNA.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6505)
  AUTHORS   Aubert,J., Stavridis,M.P., Tweedie,S., O'Reilly,M., Vierlinger,K.,
            Li,M., Ghazal,P., Pratt,T., Mason,J.O., Roy,D. and Smith,A.
  TITLE     Screening for mammalian neural genes via fluorescence-activated
            cell sorter purification of neural precursors from Sox1-gfp
            knock-in mice
  JOURNAL   Proc Natl Acad Sci U S A 100 Suppl 1 (Suppl 1), 11836-11841 (2003)
   PUBMED   12923295
REFERENCE   7  (bases 1 to 6505)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   8  (bases 1 to 6505)
  AUTHORS   Sakakibara,S., Nakamura,Y., Yoshida,T., Shibata,S., Koike,M.,
            Takano,H., Ueda,S., Uchiyama,Y., Noda,T. and Okano,H.
  TITLE     RNA-binding protein Musashi family: roles for CNS stem cells and a
            subpopulation of ependymal cells revealed by targeted disruption
            and antisense ablation
  JOURNAL   Proc Natl Acad Sci U S A 99 (23), 15194-15199 (2002)
   PUBMED   12407178
  REMARK    GeneRIF: data suggest that msi1 and msi2 are cooperatively involved
            in the proliferation and maintenance of CNS stem cell populations
REFERENCE   9  (bases 1 to 6505)
  AUTHORS   Sakakibara,S., Nakamura,Y., Satoh,H. and Okano,H.
  TITLE     Rna-binding protein Musashi2: developmentally regulated expression
            in neural precursor cells and subpopulations of neurons in
            mammalian CNS
  JOURNAL   J Neurosci 21 (20), 8091-8107 (2001)
   PUBMED   11588182
REFERENCE   10 (bases 1 to 6505)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BK001483.1 and BQ174763.1.
            
            On Jan 30, 2007 this sequence version replaced NM_054043.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BK001483.1, AK153928.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-6412              BK001483.1         1-6412
            6413-6505           BQ174763.1         1-93                c
FEATURES             Location/Qualifiers
     source          1..6505
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 52.4 cM"
     gene            1..6505
                     /gene="Msi2"
                     /gene_synonym="1700105C15Rik; Msi2h"
                     /note="musashi RNA-binding protein 2"
                     /db_xref="GeneID:76626"
                     /db_xref="MGI:MGI:1923876"
     exon            1..201
                     /gene="Msi2"
                     /gene_synonym="1700105C15Rik; Msi2h"
                     /inference="alignment:Splign:2.1.0"
     CDS             140..1180
                     /gene="Msi2"
                     /gene_synonym="1700105C15Rik; Msi2h"
                     /note="isoform 1 is encoded by transcript variant 1;
                     RNA-binding protein Musashi homolog 2; Musashi2;
                     musashi-2"
                     /codon_start=1
                     /product="RNA-binding protein Musashi homolog 2 isoform 1"
                     /protein_id="NP_473384.1"
                     /db_xref="CCDS:CCDS56796.1"
                     /db_xref="GeneID:76626"
                     /db_xref="MGI:MGI:1923876"
                     /translation="MEANGSPGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKF
                     GEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPKVAFPRRAQ
                     PKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFEN
                     EDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLG
                     YPNFVATYGRGYPGFAPSYGYQFPGFPAAAYGPVAAAAVAAARGSVLNSYSAQPNFGA
                     PASPAGSNPARPGGFPGANSPGPVADLYGPASQDSGVGNYISAASPQPGSGFGHGIAG
                     PLIATAFTNGYH"
     exon            202..242
                     /gene="Msi2"
                     /gene_synonym="1700105C15Rik; Msi2h"
                     /inference="alignment:Splign:2.1.0"
     exon            243..324
                     /gene="Msi2"
                     /gene_synonym="1700105C15Rik; Msi2h"
                     /inference="alignment:Splign:2.1.0"
     exon            325..409
                     /gene="Msi2"
                     /gene_synonym="1700105C15Rik; Msi2h"
                     /inference="alignment:Splign:2.1.0"
     exon            410..451
                     /gene="Msi2"
                     /gene_synonym="1700105C15Rik; Msi2h"
                     /inference="alignment:Splign:2.1.0"
     exon            452..544
                     /gene="Msi2"
                     /gene_synonym="1700105C15Rik; Msi2h"
                     /inference="alignment:Splign:2.1.0"
     exon            545..593
                     /gene="Msi2"
                     /gene_synonym="1700105C15Rik; Msi2h"
                     /inference="alignment:Splign:2.1.0"
     exon            594..676
                     /gene="Msi2"
                     /gene_synonym="1700105C15Rik; Msi2h"
                     /inference="alignment:Splign:2.1.0"
     exon            677..791
                     /gene="Msi2"
                     /gene_synonym="1700105C15Rik; Msi2h"
                     /inference="alignment:Splign:2.1.0"
     exon            792..866
                     /gene="Msi2"
                     /gene_synonym="1700105C15Rik; Msi2h"
                     /inference="alignment:Splign:2.1.0"
     exon            867..929
                     /gene="Msi2"
                     /gene_synonym="1700105C15Rik; Msi2h"
                     /inference="alignment:Splign:2.1.0"
     exon            930..1138
                     /gene="Msi2"
                     /gene_synonym="1700105C15Rik; Msi2h"
                     /inference="alignment:Splign:2.1.0"
     exon            1139..1211
                     /gene="Msi2"
                     /gene_synonym="1700105C15Rik; Msi2h"
                     /inference="alignment:Splign:2.1.0"
     exon            1212..6490
                     /gene="Msi2"
                     /gene_synonym="1700105C15Rik; Msi2h"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1382..1387
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Msi2"
                     /gene_synonym="1700105C15Rik; Msi2h"
                     /note="hexamer: AATATA"
     polyA_site      1419
                     /gene="Msi2"
                     /gene_synonym="1700105C15Rik; Msi2h"
                     /note="major polyA site"
     regulatory      6471..6476
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Msi2"
                     /gene_synonym="1700105C15Rik; Msi2h"
                     /note="hexamer: AATAAA"
     polyA_site      6490
                     /gene="Msi2"
                     /gene_synonym="1700105C15Rik; Msi2h"
                     /note="major polyA site"
ORIGIN      
        1 ggagcttcgc agccgccggg cggggggagg aggcggggga ggagggacgg agatctgggg
       61 ctcggagccg gccgccgctg cgctccgctt cgctgtgggg ctcggtgtgt cgggggtggg
      121 ggggcggggg ggctccgcta tggaggcaaa tgggagccca ggcacctcgg gcagcgccaa
      181 cgactcccag cacgaccccg gtaaaatgtt tatcggtgga ctgagctggc agacctcacc
      241 agatagcctt agagactatt ttagcaaatt tggagaaatt agagaatgta tggtcatgag
      301 agatcccaca acgaaacgct ccagaggctt cggtttcgtc accttcgcag acccagcaag
      361 tgtagataaa gtattaggtc agccccacca tgagttagat tccaagacga ttgacccaaa
      421 agttgcattt cctcgtcgag cgcaacctaa gatggtcaca agaacaaaga aaatcttcgt
      481 aggaggattg tctgcaaaca cagtagtgga agatgtaaag cagtatttcg agcagtttgg
      541 caaggtagag gatgcgatgc tgatgttcga caaaaccacc aacaggcaca gagggtttgg
      601 ctttgtcacc tttgagaatg aagacgttgt ggagaaagtc tgtgagattc atttccatga
      661 aatcaataat aaaatggtag aatgtaagaa agctcagccg aaagaagtca tgttcccacc
      721 tgggacaaga ggccgggccc gggggctgcc atacaccatg gatgcgttca tgcttggcat
      781 ggggatgctg ggctacccca actttgtggc aacctatggc agaggctacc ccggatttgc
      841 tcctagctat ggctaccagt tcccaggctt cccggcggca gcttatggac cagtggcagc
      901 ggcagctgtg gcagcggctc gaggatcagt cctgaatagc tacagtgctc aaccgaattt
      961 tggcgcgccc gcttccccgg caggctccaa cccggcgcgg cccggaggct tcccgggggc
     1021 caacagccca ggacctgtcg ccgatctcta cggccctgcc agccaggact ccggagtggg
     1081 gaattacata agcgcggcca gcccacagcc gggctccggc ttcggccacg gcatagctgg
     1141 acctttgatt gcaacggcct ttacaaatgg ataccactga gcaggcgctt ccattgccgt
     1201 ctcactatga gagcatacct ggatgtccag gcaagactgg gcgaagtttc tgagtggccc
     1261 tttgtttagg tgacgtcctc agacctggac ccccaccagc ctcactcctc atcccaacca
     1321 gaggtggcac acttggattg agggttgaca catctcatct cacccatcgg ctacctgctg
     1381 taatataaga caacagcttt taaacgtgta tataatccat gattttggtt tggttctgtt
     1441 tgttttcctt ggtggtcccc ctctccctct tcccttctcc ttttaaatct ccctcaatca
     1501 catttggtag tgatttttga cttagtctgg tagtcaccca gcttaatatc tagttaaagc
     1561 taaccatagt atacttgtta tatattaagg agtttttttt cttttttttt gttttctttt
     1621 ttcctttaaa gagaattttt gttttgtttt gattctgttc tcgcttttaa aggatgctga
     1681 gatggtgatg ttactctcca tttttggtac cagttctgag actgtaagac ttttcatctg
     1741 ggactttagc acacactgaa tcgaagttgt gatacgcgga gcgggaggtg ggcatagact
     1801 ctattttgtg ttgtagaagt gacatacagt tggctgctta acagactctc tagccgttca
     1861 tttttgtgac gtctctttgt taacctaagt atatctattt tcggcaataa ggtaaggacg
     1921 gccgtgtttt gagggtcttc ctttcctatg agtgcttttt cttttcttct gttcaaagag
     1981 gtcatattac aaggtttttt gaaattgtga attctaaaaa acaaaaaaca aacaaaaaaa
     2041 tgttgtaaat ataattccat taactacata gaaactatta aggaagagag aatcaaaaaa
     2101 tatttttgtg agggagttga tcctgggcag ttaggtaccc tggaaggagg ggagggaacc
     2161 tcgatgaagc cagtacaaca acagaagagc ccccccagct gccagggcac cccagacccc
     2221 cactcttcac tgttggtgtg atagacctaa gaaccacatt agcaccctgc cagcctacca
     2281 gcctctctgt gcacagcttc taatgttatg atctagctag atttttattt aaaatatgaa
     2341 aaactgcttt tcccaagacg ttttttaaaa ggaaaaaaag ctacaatttt aatatttgac
     2401 atatttaaag tttcaaagca cacttgtttt ggcttagggg aggggcaggg tggggtcatt
     2461 ctttttcagt cttaattttt aaatatctga tcattttata ttgtccgatc atttcagcac
     2521 ctccaaaggg tcctaggata ttctgcctct ctcttcaccc tgtccccaga cgggggaacc
     2581 cgtgggtcag gcgtggataa gcctgcgaga atacaccctt tctccattca ctttctattt
     2641 acaaattagg aaagcaacct ttcagtttat atatatattt tttttccttt ttgatacctc
     2701 agtgctgcaa gtatcatcag agaggctatg gaagagtttt gtgttttgtt ttttgttttg
     2761 tttttttttt taatttattg tagatgtaaa cagaatttta aaaataaaat ataaacatca
     2821 ctgcactgtg actggtgggg aaaactgaca gcttcctgtt tgtacacatt tgacattggc
     2881 tgttataata tatggtcctc agttggggaa gacacttaga atgaaggatg ttttttaatt
     2941 taactttttt ttttttttaa agaaaaatat cagtaatagg tcggcaacag cagccgtagg
     3001 aagtacaact tagggtagca ttaaagcata ctgtagtgtg gatatatttt ttttcttttt
     3061 taaaatgtga tattgacatt ttattaatat tttttaaatt gttacgttta taaatttggt
     3121 acttaaggca cagccagtgt gaggcactga acgcgacatt tattacaatg agctgctgca
     3181 ctcctacttt tataaatttt actaacaagt agactaatgt agacattcac agacgggata
     3241 gcgcagaagc atcttcacac gacaagtctc caaaaaaaaa aagctaattc agagagggcg
     3301 ggaggaagcc tgttcccgtt ctaattaagt gcaaccttgt tttatcttat tgttttattt
     3361 tttaagaaag gaaatcatgt tcttttttta tatctctata tataagatac agagttgttt
     3421 ggtaaggttt ggggtgtttt ttgttttgtt ttgttttaag tttccaaaca accaaactaa
     3481 gaaaaatgct ggatgctttt agaatacaaa acttactcaa gtcataaaat aacaaaatag
     3541 aacttttact ttaagaaaca acaacaaaga gagagagaga ctcgattccc agcaagtcag
     3601 tgtctcacaa gggcactggc taattactct tctgtccgcg ttgctgatgt cctgtcccca
     3661 gcccctgtcc atctccccca cactcccatc acctcataga acgctctttg ttgatcattg
     3721 tctgttaata atgtataaaa tggctatctt gtaagtgtgc tgtcttggta ctagtgtagt
     3781 gacttttttt ctcctcttct agtacatatt gataggtata atgtaattaa ggttttaaaa
     3841 aaaatagaca tagttattca gattaggacc agtaaggata gaactttctc ttatttatga
     3901 aaagaaaaaa aatgctaata atttgggggc agttttttcc tttttttttt tttccaagtt
     3961 caaatttact tttatttttg ctgatttgat gtggtttcaa ctaacccaag gtctcacaat
     4021 gttcaaatgg cggctgactc tacagcattc tgtaggtccc tgccccccta gctgaagggg
     4081 tgtgccatac taccttaaat gcaaacacta gatatgcaaa actggatttt tttaatttat
     4141 tttttaaaag agggaggtgt ggtatattaa aatgatttta ctaagagaaa aaaaatattt
     4201 ttttaaggat gctcagaaga aattgataat ctgtgtgaat atgttttaga tgtttatata
     4261 cattttgaag agacccagta gcccatagca caaatcttgt gaacatctga tatgttttca
     4321 agtggctacc taggataagg ttcatcatta gtacccccac ccccacccca ccgccatcta
     4381 gaagtccatc ttaaacaatt ttttgtaaat tctttcagca ctggtgtcca tctttgtctt
     4441 tgtttcagtt aagctcaata gcgaatgtgg gaccccctcc tctgaccttc cctgggggag
     4501 aaaccctctt ggctaatggc tcttccctgg cattatcaat aaccacccgg ggactctctg
     4561 gctttcagat ccatctgcct gagaccccaa ggtcctctcc tccctagagg ggaggtggag
     4621 cagcagttga ctcctggttc cctccctatt tcagcctgga tgtggggctg gtggagatgc
     4681 ctccacccca ggagcctctg catatgtggt tcgtggcctt cttctcaccc attgggaaaa
     4741 ccaaacagcc tcacactctg tccccatcgc tcattggctt aactcaagtg agaccccaac
     4801 tgggcctttg cgttttgttt ttgttttttt ttaaatcctt catgaccatt ctcttaattt
     4861 gaactcgtag cttgggcttt aaggtagcat ggctcgattg ctgtcgactt aatgttccac
     4921 tgcacagcaa ttcacggcca gtgaatgtta cacacatctt gctagactag tataaaaatc
     4981 attgggtaat tgttggttct aatgacctga aaggtgttca gtttgtgggt tttttttggg
     5041 gggggctgct tggggggttg tttttccttc tttgtttttt tttaatttga gaatttaggg
     5101 ggataatttt tggggggggg ttccaaataa aaaaatagaa agctattttg atctttagtg
     5161 caaactaggg acgtagcctc catcaccaca accacaccgc ttcgctctgc catccaccca
     5221 ccgcagcagc atcttcaaga ataaagcaat atagtttact acattttttt ttaaaattga
     5281 aggtcagcca tgctttctgt attatattgc atatgaaatt gtttacaaaa gaaacactaa
     5341 ctcatccttc tctttatcag ttgaaagtga cacacgggac agagggaaat tggagggcag
     5401 gtgagggagg ggagagggtt tttttgtatt ttggtttgtt tggttttggt ttcttttctt
     5461 gaatgtgctt tagtagccag atcctccaag gaaggcaaaa gccagccagc cagagagaga
     5521 gtagcgaagc gggcaggctg caggtaagca cactgaacaa gagacacact ggcaagctcc
     5581 cccacctcag cgagagcaga aagcgaacag ctcagcccag tcctgggcac agacactaca
     5641 caaggcaatg ctggaattga aacaatactt taataccgtt taagtttgtt tccttttttt
     5701 ttttcctctt ttttttttct ttcaccaaga aaagaaaaaa gtaaactaaa atacaaaata
     5761 caaaaacaaa caaacaaaca acaacccata taaataaaac ccacccctct ctgggaaaca
     5821 accataattc aaacatggct atttagtaat cagaaggtat tgtctcagac aggatttcat
     5881 ttccgggagg cagggcgtga ggggggaggg gagtgggact gagagacagt tccagagcct
     5941 ccagggaagg cttctactgc taactgctgt attctgtata tactgtgcca ccctgtgtgg
     6001 agtctgtgag tgtgctcttg agtagcgtgg gctagccaat ctgccattca tggtgttata
     6061 aactcggaat tccatatgta ataggatgca agtctaagcg tttcatgtgg acataaatgt
     6121 atctaaataa aacttcccct agcactgtgg ctgacctcac ccttactttt atactttagt
     6181 atgaaactga tgagaacttt ggtagtgagt atttttttta tatatataca tatatatgta
     6241 tctatatata tatatatatc tcaagcatct ttcaggtctt tgtgtgtggc tttcttaaag
     6301 ccctgttgta aaaaaaaaaa aaattactaa gtggatggca gtctctcaca tcacagatgt
     6361 ggaaagtata attttatatt tgtattttca aataaataag tttgtgaaag gtttccatcc
     6421 tctactgtgg tccagaaatc aatgtgtttg tctgacaaaa aaaataataa aataaactgt
     6481 tttgaacaga aaaaaaaaaa aaaaa
//
