LOCUS       NM_010829               3944 bp    mRNA    linear   ROD 04-MAR-2025
DEFINITION  Mus musculus mutS homolog 3 (Msh3), transcript variant 1, mRNA.
ACCESSION   NM_010829 XM_913120 XM_922649 XM_922654 XM_922659 XM_922662
            XM_922668 XM_922672 XM_922677 XM_922681
VERSION     NM_010829.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3944)
  AUTHORS   Wang,N., Zhang,S., Langfelder,P., Ramanathan,L., Gao,F.,
            Plascencia,M., Vaca,R., Gu,X., Deng,L., Dionisio,L.E., Vu,H.,
            Maciejewski,E., Ernst,J., Prasad,B.C., Vogt,T.F., Horvath,S.,
            Aaronson,J.S., Rosinski,J. and Yang,X.W.
  TITLE     Distinct mismatch-repair complex genes set neuronal CAG-repeat
            expansion rate to drive selective pathogenesis in HD mice
  JOURNAL   Cell (2025) In press
   PUBMED   39938516
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 3944)
  AUTHORS   Aldous,S.G., Smith,E.J., Landles,C., Osborne,G.F.,
            Canibano-Pico,M., Nita,I.M., Phillips,J., Zhang,Y., Jin,B.,
            Hirst,M.B., Benn,C.L., Bond,B.C., Edelmann,W., Greene,J.R. and
            Bates,G.P.
  TITLE     A CAG repeat threshold for therapeutics targeting somatic
            instability in Huntington's disease
  JOURNAL   Brain 147 (5), 1784-1798 (2024)
   PUBMED   38387080
REFERENCE   3  (bases 1 to 3944)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 3944)
  AUTHORS   Driscoll,R., Hampton,L., Abraham,N.A., Larigan,J.D., Joseph,N.F.,
            Hernandez-Vega,J.C., Geisler,S., Yang,F.C., Deninger,M., Tran,D.T.,
            Khatri,N., Godinho,B.M.D.C., Kinberger,G.A., Montagna,D.R.,
            Hirst,W.D., Guardado,C.L., Glajch,K.E., Arnold,H.M.,
            Gallant-Behm,C.L. and Weihofen,A.
  TITLE     Dose-dependent reduction of somatic expansions but not Htt
            aggregates by di-valent siRNA-mediated silencing of MSH3 in HdhQ111
            mice
  JOURNAL   Sci Rep 14 (1), 2061 (2024)
   PUBMED   38267530
  REMARK    GeneRIF: Dose-dependent reduction of somatic expansions but not Htt
            aggregates by di-valent siRNA-mediated silencing of MSH3 in HdhQ111
            mice.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3944)
  AUTHORS   Maksimov,M.O., Wu,C., Ashbrook,D.G., Villani,F., Colonna,V.,
            Mousavi,N., Ma,N., Lu,L., Pritchard,J.K., Goren,A., Williams,R.W.,
            Palmer,A.A. and Gymrek,M.
  TITLE     A novel quantitative trait locus implicates Msh3 in the propensity
            for genome-wide short tandem repeat expansions in mice
  JOURNAL   Genome Res 33 (5), 689-702 (2023)
   PUBMED   37127331
  REMARK    GeneRIF: A novel quantitative trait locus implicates Msh3 in the
            propensity for genome-wide short tandem repeat expansions in mice.
REFERENCE   6  (bases 1 to 3944)
  AUTHORS   Liu,K., Niu,L., Linton,J.P. and Crouse,G.F.
  TITLE     Characterization of the mouse Rep-3 gene: sequence similarities to
            bacterial and yeast mismatch-repair proteins
  JOURNAL   Gene 147 (2), 169-177 (1994)
   PUBMED   7926796
REFERENCE   7  (bases 1 to 3944)
  AUTHORS   Smith,M.L., Mitchell,P.J. and Crouse,G.F.
  TITLE     Analysis of the mouse Dhfr/Rep-3 major promoter region by using
            linker-scanning and internal deletion mutations and DNase I
            footprinting
  JOURNAL   Mol Cell Biol 10 (11), 6003-6012 (1990)
   PUBMED   2233729
REFERENCE   8  (bases 1 to 3944)
  AUTHORS   Linton,J.P., Yen,J.Y., Selby,E., Chen,Z., Chinsky,J.M., Liu,K.,
            Kellems,R.E. and Crouse,G.F.
  TITLE     Dual bidirectional promoters at the mouse dhfr locus: cloning and
            characterization of two mRNA classes of the divergently transcribed
            Rep-1 gene
  JOURNAL   Mol Cell Biol 9 (7), 3058-3072 (1989)
   PUBMED   2674679
REFERENCE   9  (bases 1 to 3944)
  AUTHORS   Fujii,H. and Shimada,T.
  TITLE     Isolation and characterization of cDNA clones derived from the
            divergently transcribed gene in the region upstream from the human
            dihydrofolate reductase gene
  JOURNAL   J Biol Chem 264 (17), 10057-10064 (1989)
   PUBMED   2722860
REFERENCE   10 (bases 1 to 3944)
  AUTHORS   McGrogan,M., Simonsen,C.C., Smouse,D.T., Farnham,P.J. and
            Schimke,R.T.
  TITLE     Heterogeneity at the 5' termini of mouse dihydrofolate reductase
            mRNAs. Evidence for multiple promoter regions
  JOURNAL   J Biol Chem 260 (4), 2307-2314 (1985)
   PUBMED   2982814
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC161588.2 and AC155263.2.
            
            On Apr 5, 2022 this sequence version replaced NM_010829.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK133907.1, AK161089.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-245               AC161588.2         42351-42595
            246-363             AC161588.2         44016-44133
            364-584             AC161588.2         45907-46127
            585-773             AC161588.2         48021-48209
            774-890             AC161588.2         49913-50029
            891-1008            AC161588.2         50508-50625
            1009-1154           AC161588.2         52257-52402
            1155-1321           AC161588.2         54946-55112
            1322-1434           AC161588.2         84672-84784
            1435-1549           AC161588.2         87799-87913
            1550-1634           AC161588.2         97000-97084
            1635-1744           AC161588.2         98096-98205
            1745-1877           AC161588.2         111349-111481
            1878-2065           AC161588.2         122441-122628
            2066-2234           AC161588.2         123238-123406
            2235-2299           AC161588.2         131367-131431
            2300-2416           AC161588.2         133521-133637
            2417-2524           AC161588.2         140556-140663
            2525-2636           AC161588.2         147420-147531
            2637-2794           AC161588.2         161627-161784
            2795-2981           AC155263.2         197878-198064       c
            2982-3111           AC155263.2         195724-195853       c
            3112-3283           AC155263.2         190238-190409       c
            3284-3944           AC155263.2         186654-187314       c
FEATURES             Location/Qualifiers
     source          1..3944
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 47.63 cM"
     gene            1..3944
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /note="mutS homolog 3"
                     /db_xref="GeneID:17686"
                     /db_xref="MGI:MGI:109519"
     exon            1..245
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     CDS             108..3395
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /note="isoform 1 is encoded by transcript variant 1; DNA
                     mismatch repair protein Msh3; protein repair-1; protein
                     repair-3"
                     /codon_start=1
                     /product="DNA mismatch repair protein Msh3 isoform 1"
                     /protein_id="NP_034959.2"
                     /db_xref="CCDS:CCDS49326.1"
                     /db_xref="GeneID:17686"
                     /db_xref="MGI:MGI:109519"
                     /translation="MPRGKSASGGSTAAGPGPGRQTVLSRFFRSAGSLRSSASSTEPA
                     EKVTEGDSRKRSLGNGGPTKKKARKVPEKEEENISVAAHHPEAKKCLRPRIVLKSLEK
                     LKEFCCDSALPQNRVQTEALRERLEVLPRCTDFEDITLQRAKNAVLSEDSKSQANQKD
                     SQFGPCPEVFQKTSDCKPFNKRSKSVYTPLELQYLDMKQQHKDAVLCVECGYKYRFFG
                     EDAEIAARELNIYCHLDHNFMTASIPTHRLFVHVRRLVAKGYKVGVVKQTETAALKAI
                     GDNKSSVFSRKLTALYTKSTLIGEDVNPLIRLDDSVNIDEVMTDTSTNYLLCIYEEKE
                     NIKDKKKGNLSVGIVGVQPATGEVVFDCFQDSASRLELETRISSLQPVELLLPSDLSV
                     PTEMLIQRATNVSVRDDRIRVERMNNTYFEYSHAFQTVTEFYAREIVDSQGSQSLSGV
                     INLEKPVICALAAVIRYLKEFNLEKMLSKPESFKQLSSGMEFMRINGTTLRNLEILQN
                     QTDMKTKGSLLWVLDHTKTSFGRRKLKNWVTQPLLKLREINARLDAVSDVLHSESSVF
                     EQIENLLRKLPDVERGLCSIYHKKCSTQEFFLIVKSLCQLKSELQALMPAVNSHVQSD
                     LLRALIVEAPELLSPVEHYLKVLNGPAAKVGDKTELFKDLSDFPLIKKRKNEIQEVIH
                     SIQMRLQEFRKILKLPSLQYVTVSGQEFMIEIKNSAVSCIPADWVKVGSTKAVSRFHP
                     PFIVESYRRLNQLREQLVLDCNAEWLGFLENFGEHYHTLCKAVDHLATVDCIFSLAKV
                     AKQGNYCRPTLQEEKKIIIKNGRHPMIDVLLGEQDQFVPNSTSLSQDSERVMIITGPN
                     MGGKSSYIKQVALVTIMAQIGSYVPAEEATIGIVDGIFTRMGAADNIYKGRSTFMEEL
                     TDTAEIIRRASPQSLVILDELGRGTSTHDGIAIAYATLEYFIRDVKSLTLFVTHYPPV
                     CELEKCYPEQVGNYHMGFLVNEDESKQDSGDMEQMPDSVTFLYQITRGIAARSYGLNV
                     AKLADVPREVLQKAAHKSKELEGLVSLRRKRLECFTDLWTTHSVKDLHTWADKLEMEE
                     IQTSLPH"
     exon            246..363
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     exon            364..584
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     exon            585..773
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     exon            774..890
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     exon            891..1008
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     exon            1009..1154
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     exon            1155..1321
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     exon            1322..1434
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     exon            1435..1549
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     exon            1550..1634
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     exon            1635..1744
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     exon            1745..1877
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     exon            1878..2065
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     exon            2066..2234
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     exon            2235..2299
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     exon            2300..2416
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     exon            2417..2524
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     exon            2525..2636
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     exon            2637..2794
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     exon            2795..2981
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     exon            2982..3111
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     exon            3112..3283
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     exon            3284..3944
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3926..3931
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /note="hexamer: AATAAA"
     polyA_site      3944
                     /gene="Msh3"
                     /gene_synonym="D13Em1; REP-1; Rep-3; Rep3"
                     /note="major polyA site"
ORIGIN      
        1 gcccccaagg ccggtcccgc acaggttgag gcgtgcgcgc gcgcaggcgc gagaaagtgc
       61 ggccgcgcgc tcgcgctcct agcaggccgg ctcttctgca cactgcaatg ccccgcggga
      121 aatccgcgtc gggaggctct actgccgccg gcccaggccc ggggaggcaa acggttctaa
      181 gccggttctt caggtctgcg ggaagcctaa gatccagcgc gtcctccacg gagccagcag
      241 agaaggtgac agaaggtgac agcaggaaga ggtcactggg aaatggtggg cccactaaga
      301 aaaaagcaag gaaagttcca gagaaggagg aagaaaacat ctcagtagca gctcaccacc
      361 ctgaggcaaa gaaatgtctg aggcccagga ttgttttaaa gtccctggaa aagttgaaag
      421 aattctgctg tgattctgcc ctccctcaaa acagagtcca gacagaagct cttcgggaga
      481 gacttgaagt tctgccaagg tgtactgatt ttgaagatat cactctgcaa cgtgcaaaga
      541 atgcggtttt gtccgaagat tccaaatctc aggctaatca gaaagacagt caatttggac
      601 cctgccctga agttttccag aagacttccg attgtaaacc ttttaacaag cgatccaaga
      661 gcgtctatac accgttagaa ctgcagtact tagatatgaa gcagcagcat aaagacgcag
      721 ttttgtgtgt ggagtgtggt tacaagtaca gattctttgg ggaagatgca gaaattgctg
      781 cccgggaact caatatttat tgccacttag accacaactt tatgactgca agcataccta
      841 cccacagact gttcgtgcat gtccgccgac ttgtggccaa agggtacaag gtgggagttg
      901 tgaagcaaac tgaaactgcc gcattaaagg ccatcggaga caataaaagt tctgtcttct
      961 cccggaaatt gaccgctctt tatacgaaat ccacacttat tggtgaagat gtgaatcctc
     1021 tcatcaggct ggatgattct gtaaatatcg atgaggtaat gacagataca tctaccaact
     1081 atcttctgtg tatctacgaa gaaaaggaga acattaaaga caaaaagaag gggaaccttt
     1141 ccgttggtat cgtgggagtg cagcccgcaa ctggcgaggt tgtgtttgac tgcttccagg
     1201 actctgcttc cagactggag ctggagactc gcatatcaag cctgcagcct gtggaattac
     1261 tgcttccctc cgacctgtct gtgccaacag agatgctcat ccaaagagcc accaatgtca
     1321 gtgtgcggga tgacaggatt cgagtagaaa ggatgaataa tacttacttt gaatacagcc
     1381 atgctttcca gacagttacg gagttttatg ctagagagat agttgacagc cagggctctc
     1441 agagtctctc tggtgtcatt aacttggaga agcctgtgat ctgcgccttg gctgccgtaa
     1501 taaggtacct caaggaattt aacctggaaa agatgctgtc caaacccgag agttttaaac
     1561 agctgtcaag tggaatggaa ttcatgagaa ttaatgggac cacgctaagg aatctggaga
     1621 tccttcagaa tcagactgat atgaagacca aaggaagctt gctttgggtt ttagaccaca
     1681 ctaaaacttc atttgggaga aggaagttaa agaattgggt tacccagcca ctgcttaaat
     1741 taagggaaat aaatgcccga cttgatgcag tatctgatgt tctccactca gaatccagtg
     1801 tgtttgagca gatagaaaac cttcttcgta agttaccgga tgtcgagaga ggactatgta
     1861 gcatttatca caagaagtgc tctacccaag agttcttctt gatcgtcaaa agcctatgtc
     1921 aactgaagtc agagcttcaa gcattaatgc ctgctgttaa ttcccacgtt cagtccgact
     1981 tactccgagc actcatcgtg gaggctcctg agctcctcag cccagtggaa cattacttaa
     2041 aggttctgaa tgggccagct gccaaagttg gcgataaaac tgaattattc aaagacctct
     2101 ctgacttccc tttaataaaa aagaggaaaa atgaaattca ggaagtcatt cacagcatcc
     2161 aaatgcgttt acaggaattt cggaaaatat taaaacttcc ttctttacag tatgtgactg
     2221 tatcaggaca agagtttatg attgaaataa agaactcggc tgtatcttgc atcccagctg
     2281 attgggtgaa ggttggaagc acaaaagctg tgagccgctt tcaccctccc ttcatcgtgg
     2341 aaagctacag acgtctgaat cagctccggg agcagctagt ccttgactgc aatgctgaat
     2401 ggcttggctt cctagagaat tttggtgaac attatcacac tttgtgtaag gctgtggatc
     2461 acctagcaac tgttgactgt attttctccc tggccaaggt cgctaaacaa ggaaattact
     2521 gcaggccaac tctacaagaa gaaaagaaga tcatcataaa aaatggaagg caccctatga
     2581 ttgatgtgtt gctgggtgaa caagatcagt ttgtgcccaa cagtacgagt ttatcacagg
     2641 actcggagag agtaatgata atcaccggac caaacatggg tgggaaaagc tcctacataa
     2701 aacaggttgc actggttacc atcatggctc agattggctc ctacgtccct gcagaggaag
     2761 ccacaattgg gattgtggat ggcattttca caaggatggg tgctgcagac aatatataca
     2821 aaggccggag tactttcatg gaagaactga cggacacagc ggaaataatc aggagagcgt
     2881 ccccacagtc cttggttatc ctggatgagc tggggagagg gacaagcacc catgacggaa
     2941 tcgccatcgc ctatgcaact ctagagtatt ttatcagaga cgtgaaatcc ttaacactgt
     3001 tcgttaccca ctatccacca gtctgtgaac tagaaaaatg ttacccagaa caagtgggga
     3061 attaccacat gggattcttg gtcaatgaag atgaaagcaa gcaggactca ggtgacatgg
     3121 agcagatgcc ggattctgtc acttttctct atcagataac ccgaggaatt gcagcgagaa
     3181 gttatggact taatgtggcg aagttagcag atgtacctag agaagtctta cagaaagccg
     3241 cgcacaagtc taaggagctg gaaggcttag tcagcctgag aaggaaaagg cttgaatgtt
     3301 ttaccgactt atggacgaca cacagtgtga aggacctgca cacatgggca gataagctgg
     3361 aaatggagga aatacagact tctctcccac attaaaatga aaactgcatt tttggagtaa
     3421 aatacagaga actgaagatt caaactgtac aaaacaactc tgtggcaaca gccgtctctg
     3481 tggtcttcct tttgagatgg cttctgctct gtgaagggag cttttcaggc tcttgtcctc
     3541 ctgctttcag aagaaaaaga caatggagtg taaaggcctc aattttccta ggcagtacat
     3601 ttcataccaa agcgggttct tctaagtaaa acctaaaacg gaggttcttg gtgcctacat
     3661 tatcagaggg gcagtgccta tttaggttca gacaattgac aacaggctaa tctgacagga
     3721 acctactttt gtgagaacta aagaacttta taatgccagg gtttgctcac caaacacata
     3781 aacgttttta tgagaaggag aatcgcgaag cttctagaag ccagagcaca ggaaggaaag
     3841 gccacatgaa gtgtgaaggg ctaaatgtcg tcatcttttt aacagcttga aggttggtgt
     3901 ataaaattat tttgtcattt acttaaataa aaatatggaa tgaa
//
