LOCUS       NM_019544                567 bp    mRNA    linear   ROD 28-JAN-2025
DEFINITION  Mus musculus mesogenin 1 (Msgn1), mRNA.
ACCESSION   NM_019544
VERSION     NM_019544.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 567)
  AUTHORS   Hung,Y.S., Lin,W.M., Wang,Y.C., Kuo,W.C., Chen,Y.Y., Fann,M.J.,
            Yu,J.Y. and Wong,Y.H.
  TITLE     Protogenin facilitates trunk-to-tail HOX code transition via
            modulating GDF11/SMAD2 signaling in mammalian embryos
  JOURNAL   Commun Biol 7 (1), 1669 (2024)
   PUBMED   39702818
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 567)
  AUTHORS   Genuth,N.R., Shi,Z., Kunimoto,K., Hung,V., Xu,A.F., Kerr,C.H.,
            Tiu,G.C., Oses-Prieto,J.A., Salomon-Shulman,R.E.A., Axelrod,J.D.,
            Burlingame,A.L., Loh,K.M. and Barna,M.
  TITLE     A stem cell roadmap of ribosome heterogeneity reveals a function
            for RPL10A in mesoderm production
  JOURNAL   Nat Commun 13 (1), 5491 (2022)
   PUBMED   36123354
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 567)
  AUTHORS   Li,B., Brusman,L., Dahlka,J. and Niswander,L.A.
  TITLE     TMEM132A ensures mouse caudal neural tube closure and regulates
            integrin-based mesodermal migration
  JOURNAL   Development 149 (17) (2022)
   PUBMED   35950911
REFERENCE   4  (bases 1 to 567)
  AUTHORS   Falk,H.J., Tomita,T., Monke,G., McDole,K. and Aulehla,A.
  TITLE     Imaging the onset of oscillatory signaling dynamics during mouse
            embryo gastrulation
  JOURNAL   Development 149 (13) (2022)
   PUBMED   35686648
REFERENCE   5  (bases 1 to 567)
  AUTHORS   Campbell,G.P., Farkas,D.R. and Chapman,D.L.
  TITLE     Ectopic expression of T in the paraxial mesoderm disrupts somite
            maturation in the mouse
  JOURNAL   Dev Biol 485, 37-49 (2022)
   PUBMED   35276131
REFERENCE   6  (bases 1 to 567)
  AUTHORS   Nam,J.S., Turcotte,T.J., Smith,P.F., Choi,S. and Yoon,J.K.
  TITLE     Mouse cristin/R-spondin family proteins are novel ligands for the
            Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent
            gene expression
  JOURNAL   J Biol Chem 281 (19), 13247-13257 (2006)
   PUBMED   16543246
REFERENCE   7  (bases 1 to 567)
  AUTHORS   Bessho,Y., Sakata,R., Komatsu,S., Shiota,K., Yamada,S. and
            Kageyama,R.
  TITLE     Dynamic expression and essential functions of Hes7 in somite
            segmentation
  JOURNAL   Genes Dev 15 (20), 2642-2647 (2001)
   PUBMED   11641270
REFERENCE   8  (bases 1 to 567)
  AUTHORS   Kume,T., Jiang,H., Topczewska,J.M. and Hogan,B.L.
  TITLE     The murine winged helix transcription factors, Foxc1 and Foxc2, are
            both required for cardiovascular development and somitogenesis
  JOURNAL   Genes Dev 15 (18), 2470-2482 (2001)
   PUBMED   11562355
REFERENCE   9  (bases 1 to 567)
  AUTHORS   Yoon,J.K. and Wold,B.
  TITLE     The bHLH regulator pMesogenin1 is required for maturation and
            segmentation of paraxial mesoderm
  JOURNAL   Genes Dev 14 (24), 3204-3214 (2000)
   PUBMED   11124811
REFERENCE   10 (bases 1 to 567)
  AUTHORS   Yoon,J.K., Moon,R.T. and Wold,B.
  TITLE     The bHLH class protein pMesogenin1 can specify paraxial mesoderm
            phenotypes
  JOURNAL   Dev Biol 222 (2), 376-391 (2000)
   PUBMED   10837126
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF261105.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AF261105.1, BC116996.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..567
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 5.58 cM"
     gene            1..567
                     /gene="Msgn1"
                     /gene_synonym="Msgn; pMsgn1"
                     /note="mesogenin 1"
                     /db_xref="GeneID:56184"
                     /db_xref="MGI:MGI:1860483"
     CDS             1..567
                     /gene="Msgn1"
                     /gene_synonym="Msgn; pMsgn1"
                     /note="paraxial mesoderm-specific expression and
                     regulatory capacities; paraxial mesoderm-specific
                     mesogenin1; pMesogenin1"
                     /codon_start=1
                     /product="mesogenin-1"
                     /protein_id="NP_062417.1"
                     /db_xref="CCDS:CCDS25814.1"
                     /db_xref="GeneID:56184"
                     /db_xref="MGI:MGI:1860483"
                     /translation="MDNLGETFLSLEDGLDSSDTAGLLASWDWKSRARPLELVQESPT
                     QSLSPAPSLESYSEVALPCGHSGASTGGSDGYGSHEAAGLVELDYSMLAFQPPYLHTA
                     GGLKGQKGSKVKMSVQRRRKASEREKLRMRTLADALHTLRNYLPPVYSQRGQPLTKIQ
                     TLKYTIKYIGELTDLLNSSGREPRPQSV"
     exon            1..567
                     /gene="Msgn1"
                     /gene_synonym="Msgn; pMsgn1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggacaacc tgggtgagac cttcctcagc ctggaggatg gcctggactc ttctgacacc
       61 gctggtctgc tggcctcctg ggactggaaa agcagagcca ggcccttgga gctggtccag
      121 gagtccccca ctcaaagcct ctccccagct ccttctctgg agtcctactc tgaggtcgca
      181 ctgccctgcg ggcacagtgg ggccagcaca ggaggcagcg atggctacgg cagtcacgag
      241 gctgccggct tagtcgagct ggattacagc atgttggctt ttcaacctcc ctatctacac
      301 actgctggtg gcctcaaagg ccagaaaggc agcaaagtca agatgtctgt ccagcggaga
      361 cggaaggcca gcgagagaga gaaactcagg atgcggacct tagccgatgc cctccacacg
      421 ctccggaatt acctgccgcc tgtctacagc cagagaggcc aaccgctcac caagatccag
      481 acactcaagt acaccatcaa gtacatcggg gaactcacag acctcctcaa cagcagcggg
      541 agagagccca ggccacagag tgtgtga
//
