LOCUS       NM_080456                795 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus mitochondrial ribosomal protein S6 (Mrps6), mRNA.
ACCESSION   NM_080456 XM_489608
VERSION     NM_080456.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 795)
  AUTHORS   Lin,D., Yu,J., Lin,L., Ou,Q. and Quan,H.
  TITLE     MRPS6 modulates glucose-stimulated insulin secretion in mouse islet
            cells through mitochondrial unfolded protein response
  JOURNAL   Sci Rep 13 (1), 16173 (2023)
   PUBMED   37758822
  REMARK    GeneRIF: MRPS6 modulates glucose-stimulated insulin secretion in
            mouse islet cells through mitochondrial unfolded protein response.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 795)
  AUTHORS   Cheong,A., Lingutla,R. and Mager,J.
  TITLE     Expression analysis of mammalian mitochondrial ribosomal protein
            genes
  JOURNAL   Gene Expr Patterns 38, 119147 (2020)
   PUBMED   32987154
REFERENCE   3  (bases 1 to 795)
  AUTHORS   Greber,B.J. and Ban,N.
  TITLE     Structure and Function of the Mitochondrial Ribosome
  JOURNAL   Annu Rev Biochem 85, 103-132 (2016)
   PUBMED   27023846
  REMARK    Review article
REFERENCE   4  (bases 1 to 795)
  AUTHORS   Amunts,A., Brown,A., Toots,J., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Ribosome. The structure of the human mitochondrial ribosome
  JOURNAL   Science 348 (6230), 95-98 (2015)
   PUBMED   25838379
REFERENCE   5  (bases 1 to 795)
  AUTHORS   Dorval,V., Mandemakers,W., Jolivette,F., Coudert,L., Mazroui,R., De
            Strooper,B. and Hebert,S.S.
  TITLE     Gene and MicroRNA transcriptome analysis of Parkinson's related
            LRRK2 mouse models
  JOURNAL   PLoS One 9 (1), e85510 (2014)
   PUBMED   24427314
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 795)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   7  (bases 1 to 795)
  AUTHORS   Gitton,Y., Dahmane,N., Baik,S., Ruiz i Altaba,A., Neidhardt,L.,
            Scholze,M., Herrmann,B.G., Kahlem,P., Benkahla,A., Schrinner,S.,
            Yildirimman,R., Herwig,R., Lehrach,H. and Yaspo,M.L.
  CONSRTM   HSA21 expression map initiative
  TITLE     A gene expression map of human chromosome 21 orthologues in the
            mouse
  JOURNAL   Nature 420 (6915), 586-590 (2002)
   PUBMED   12466855
REFERENCE   8  (bases 1 to 795)
  AUTHORS   Reymond,A., Marigo,V., Yaylaoglu,M.B., Leoni,A., Ucla,C.,
            Scamuffa,N., Caccioppoli,C., Dermitzakis,E.T., Lyle,R., Banfi,S.,
            Eichele,G., Antonarakis,S.E. and Ballabio,A.
  TITLE     Human chromosome 21 gene expression atlas in the mouse
  JOURNAL   Nature 420 (6915), 582-586 (2002)
   PUBMED   12466854
REFERENCE   9  (bases 1 to 795)
  AUTHORS   Reymond,A., Camargo,A.A., Deutsch,S., Stevenson,B.J.,
            Parmigiani,R.B., Ucla,C., Bettoni,F., Rossier,C., Lyle,R.,
            Guipponi,M., de Souza,S., Iseli,C., Jongeneel,C.V., Bucher,P.,
            Simpson,A.J. and Antonarakis,S.E.
  TITLE     Nineteen additional unpredicted transcripts from human chromosome
            21
  JOURNAL   Genomics 79 (6), 824-832 (2002)
   PUBMED   12036297
REFERENCE   10 (bases 1 to 795)
  AUTHORS   Suzuki,T., Terasaki,M., Takemoto-Hori,C., Hanada,T., Ueda,T.,
            Wada,A. and Watanabe,K.
  TITLE     Proteomic analysis of the mammalian mitochondrial ribosome.
            Identification of protein components in the 28 S small subunit
  JOURNAL   J Biol Chem 276 (35), 33181-33195 (2001)
   PUBMED   11402041
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC027271.1.
            
            On Sep 3, 2004 this sequence version replaced XM_489608.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC027271.1, CF618128.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..795
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="FVB/N"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 53.44 cM"
     gene            1..795
                     /gene="Mrps6"
                     /note="mitochondrial ribosomal protein S6"
                     /db_xref="GeneID:121022"
                     /db_xref="MGI:MGI:2153111"
     exon            1..145
                     /gene="Mrps6"
                     /inference="alignment:Splign:2.1.0"
     CDS             101..478
                     /gene="Mrps6"
                     /note="28S ribosomal protein S6, mitochondrial; S6mt;
                     MRP-S6"
                     /codon_start=1
                     /product="small ribosomal subunit protein bS6m"
                     /protein_id="NP_536704.1"
                     /db_xref="CCDS:CCDS28332.1"
                     /db_xref="GeneID:121022"
                     /db_xref="MGI:MGI:2153111"
                     /translation="MPRYELALILKAMRRPETAAALKRTIESLMDRGAIVRNLESLGE
                     RALPYRISSHSQQHSRGGYFLVDFYAPTSAVENILEHLARDIDVVRPNIVKHPLTQEV
                     KECDGIVPVPLEEKLYSTKRRKK"
     exon            146..285
                     /gene="Mrps6"
                     /inference="alignment:Splign:2.1.0"
     exon            286..780
                     /gene="Mrps6"
                     /inference="alignment:Splign:2.1.0"
     regulatory      759..764
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrps6"
                     /note="hexamer: AATAAA"
     polyA_site      780
                     /gene="Mrps6"
                     /note="major polyA site"
ORIGIN      
        1 ggagctgacc ggccgtgttc ctctctcgtc ttcctctgcg ccccgcgtcc ccgccctcgc
       61 gaccccggct ctcctggact cggcgccgcc aacctgggcg atgccccgct acgagttggc
      121 tttgattctg aaagccatgc ggcggccaga gaccgctgct gctttgaaac gtacaataga
      181 atccctgatg gaccgaggag ccatagtgag gaacttggaa agcctgggtg agcgtgcgct
      241 cccctacagg atctcgagtc acagccagca gcacagccga ggagggtatt tcctggtgga
      301 tttttatgct ccgacaagtg ctgtggagaa catactggaa cacttggcgc gagacattga
      361 cgtggttaga ccaaatattg tgaaacaccc tctgacccag gaagtaaaag agtgtgacgg
      421 catagtccca gtcccacttg aagaaaaact gtattcaaca aagaggagga agaagtgaga
      481 agattcacca gattctggcc ttatatttaa tcctaagggc actatgggtg ctgctaggtt
      541 gttgtctagg atactttagc ccatgaccat tttgctgcag gaggtagaaa ctgctggccg
      601 agacctgccc tgatgtctct gctgagattt catcccactt gtggggtttg tcgggagtgg
      661 gggtgttcac agtaccactg tagcgtttcc aagagcaaaa tgtttgtcat tcacacttgg
      721 ttgtcttgca agcctatatg gaacactggg agcagagtaa taaacatgac tttatcaaca
      781 aaaaaaaaaa aaaaa
//
