LOCUS       NM_020560               1536 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus mitochondrial ribosomal protein S31 (Mrps31), mRNA.
ACCESSION   NM_020560
VERSION     NM_020560.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1536)
  AUTHORS   Cheong,A., Lingutla,R. and Mager,J.
  TITLE     Expression analysis of mammalian mitochondrial ribosomal protein
            genes
  JOURNAL   Gene Expr Patterns 38, 119147 (2020)
   PUBMED   32987154
REFERENCE   2  (bases 1 to 1536)
  AUTHORS   Doucet-Beaupre,H., Gilbert,C., Profes,M.S., Chabrat,A., Pacelli,C.,
            Giguere,N., Rioux,V., Charest,J., Deng,Q., Laguna,A., Ericson,J.,
            Perlmann,T., Ang,S.L., Cicchetti,F., Parent,M., Trudeau,L.E. and
            Levesque,M.
  TITLE     Lmx1a and Lmx1b regulate mitochondrial functions and survival of
            adult midbrain dopaminergic neurons
  JOURNAL   Proc Natl Acad Sci U S A 113 (30), E4387-E4396 (2016)
   PUBMED   27407143
REFERENCE   3  (bases 1 to 1536)
  AUTHORS   Greber,B.J. and Ban,N.
  TITLE     Structure and Function of the Mitochondrial Ribosome
  JOURNAL   Annu Rev Biochem 85, 103-132 (2016)
   PUBMED   27023846
  REMARK    Review article
REFERENCE   4  (bases 1 to 1536)
  AUTHORS   Amunts,A., Brown,A., Toots,J., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Ribosome. The structure of the human mitochondrial ribosome
  JOURNAL   Science 348 (6230), 95-98 (2015)
   PUBMED   25838379
REFERENCE   5  (bases 1 to 1536)
  AUTHORS   Tang,F., Barbacioru,C., Nordman,E., Bao,S., Lee,C., Wang,X.,
            Tuch,B.B., Heard,E., Lao,K. and Surani,M.A.
  TITLE     Deterministic and stochastic allele specific gene expression in
            single mouse blastomeres
  JOURNAL   PLoS One 6 (6), e21208 (2011)
   PUBMED   21731673
REFERENCE   6  (bases 1 to 1536)
  AUTHORS   Sansom,S.N., Griffiths,D.S., Faedo,A., Kleinjan,D.J., Ruan,Y.,
            Smith,J., van Heyningen,V., Rubenstein,J.L. and Livesey,F.J.
  TITLE     The level of the transcription factor Pax6 is essential for
            controlling the balance between neural stem cell self-renewal and
            neurogenesis
  JOURNAL   PLoS Genet 5 (6), e1000511 (2009)
   PUBMED   19521500
REFERENCE   7  (bases 1 to 1536)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   8  (bases 1 to 1536)
  AUTHORS   Osipovich,A.B., Singh,A. and Ruley,H.E.
  TITLE     Post-entrapment genome engineering: first exon size does not affect
            the expression of fusion transcripts generated by gene entrapment
  JOURNAL   Genome Res 15 (3), 428-435 (2005)
   PUBMED   15741512
REFERENCE   9  (bases 1 to 1536)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   10 (bases 1 to 1536)
  AUTHORS   Arden,S.D., Roep,B.O., Neophytou,P.I., Usac,E.F., Duinkerken,G., de
            Vries,R.R. and Hutton,J.C.
  TITLE     Imogen 38: a novel 38-kD islet mitochondrial autoantigen recognized
            by T cells from a newly diagnosed type 1 diabetic patient
  JOURNAL   J Clin Invest 97 (2), 551-561 (1996)
   PUBMED   8567980
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY237441.1 and AK005110.1.
            
            On May 7, 2009 this sequence version replaced NM_020560.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK005110.1, AK019202.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-42                BY237441.1         3-44
            43-1536             AK005110.1         2-1495
FEATURES             Location/Qualifiers
     source          1..1536
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 11.28 cM"
     gene            1..1536
                     /gene="Mrps31"
                     /gene_synonym="1500002D03Rik; Imogen38; Imogen44"
                     /note="mitochondrial ribosomal protein S31"
                     /db_xref="GeneID:57312"
                     /db_xref="MGI:MGI:1913153"
     exon            1..245
                     /gene="Mrps31"
                     /gene_synonym="1500002D03Rik; Imogen38; Imogen44"
                     /inference="alignment:Splign:2.1.0"
     CDS             127..1281
                     /gene="Mrps31"
                     /gene_synonym="1500002D03Rik; Imogen38; Imogen44"
                     /note="islet mitochondrial antigen, 38 kD; 28S ribosomal
                     protein S31, mitochondrial; S31mt; MRP-S31; imogen 38;
                     small ribosomal subunit protein mS31"
                     /codon_start=1
                     /product="small ribosomal subunit protein mS31 precursor"
                     /protein_id="NP_065585.1"
                     /db_xref="CCDS:CCDS22176.1"
                     /db_xref="GeneID:57312"
                     /db_xref="MGI:MGI:1913153"
                     /translation="MLHRIPAFLRPRPFSGLPLSCGNRDVSVAVLPAAQSGAVRTENN
                     IQRHFCTSRSICSKKVDQSVPANEISQKAAESQGRGKETLKKDLLDIIKDMKVDLSTA
                     NVKTPKPRGRKPSASLEATVDRLQKAPEDPPKKRNEFLSPELVAAASAVADSLPFDKQ
                     TTKSELLRQLQQHEEELRAQKDREKRRISFTHIISNMKIAKSPSGRASTRPQHQIQFD
                     EDMDSSLKQEKPTDFRKRKYLFKGKRLSIFADKAFADEPPEPEASPSLWEIEFAKQLA
                     SVADQPFENGFEEMIQWTKEGKLWEFPVNNEAGLDDDGSEFHEHIFLDKYLEDFPKQG
                     PIRLFMELVTCGLSKNPYLSVKQKVEHIEWFRNYFNEKRDILKENNIAFT"
     exon            246..533
                     /gene="Mrps31"
                     /gene_synonym="1500002D03Rik; Imogen38; Imogen44"
                     /inference="alignment:Splign:2.1.0"
     exon            534..692
                     /gene="Mrps31"
                     /gene_synonym="1500002D03Rik; Imogen38; Imogen44"
                     /inference="alignment:Splign:2.1.0"
     exon            693..833
                     /gene="Mrps31"
                     /gene_synonym="1500002D03Rik; Imogen38; Imogen44"
                     /inference="alignment:Splign:2.1.0"
     exon            834..907
                     /gene="Mrps31"
                     /gene_synonym="1500002D03Rik; Imogen38; Imogen44"
                     /inference="alignment:Splign:2.1.0"
     exon            908..1051
                     /gene="Mrps31"
                     /gene_synonym="1500002D03Rik; Imogen38; Imogen44"
                     /inference="alignment:Splign:2.1.0"
     exon            1052..1536
                     /gene="Mrps31"
                     /gene_synonym="1500002D03Rik; Imogen38; Imogen44"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1323..1328
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrps31"
                     /gene_synonym="1500002D03Rik; Imogen38; Imogen44"
                     /note="hexamer: ATTAAA"
     regulatory      1333..1338
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrps31"
                     /gene_synonym="1500002D03Rik; Imogen38; Imogen44"
                     /note="hexamer: AATAGA"
     polyA_site      1345
                     /gene="Mrps31"
                     /gene_synonym="1500002D03Rik; Imogen38; Imogen44"
                     /note="major polyA site"
     polyA_site      1351
                     /gene="Mrps31"
                     /gene_synonym="1500002D03Rik; Imogen38; Imogen44"
                     /note="major polyA site"
ORIGIN      
        1 gcggaacagt gcaggctgga aaacatctcg gaggacattt ttggcagagg gacgaaccag
       61 ttcagctgtg cacttcttgg cgcttgtgct tccggctgtg ctctggtttg agtttgtatt
      121 tacacgatgc tccacagaat cccggcattt ctacgccctc gccctttctc gggcctccct
      181 ttgtcctgtg gaaaccggga cgtctcggtg gctgtgctac ccgcggctca gtccggagct
      241 gtgaggacag aaaataatat ccaaagacat ttttgcacta gcagatcaat ctgtagcaag
      301 aaagttgacc agtctgttcc agccaatgaa atttcccaga aggcagcaga gagccaaggc
      361 aggggaaagg agactttgaa aaaagacctg ctggacatta ttaaggacat gaaagttgac
      421 ctgagcacag caaatgtgaa aacaccaaag ccacgtggca gaaaaccttc tgccagtctg
      481 gaggctaccg ttgacaggct tcagaaagct ccggaagacc ctccaaagaa gaggaatgag
      541 ttcctgagtc ctgagttggt ggctgcagcg tcggctgttg cagattccct accttttgac
      601 aagcagacaa ccaagtcaga gctgctcagg cagctgcagc aacacgagga ggagttgagg
      661 gctcagaagg acagagagaa gcgcaggatc agcttcactc acataatatc aaatatgaaa
      721 attgccaagt ctccctccgg gagagctagt acaaggccac agcaccagat tcagtttgac
      781 gaagacatgg acagttctct taagcaggag aagccaactg atttcagaaa aaggaaatat
      841 ttattcaagg ggaaaagact ttcaattttt gctgataagg cgtttgctga tgaaccacct
      901 gaaccagaag catcaccttc tctctgggag atagagtttg ctaagcagtt agcctcggta
      961 gctgaccagc cctttgagaa tggatttgag gagatgatac agtggaccaa ggaggggaag
     1021 ctgtgggagt tcccagtcaa caatgaagca ggtttagatg acgatggctc cgaattccat
     1081 gagcatatat ttttggataa gtacctggag gatttcccca agcaaggacc aatccgtctg
     1141 ttcatggagc tggtgacctg tggcctttcc aaaaacccat atctgagtgt taaacagaag
     1201 gtcgagcaca tagagtggtt tagaaattat tttaatgaaa aaagagatat tctcaaagaa
     1261 aataatatag cgttcactta acatcacaaa gaaaaaaatt ttatttaaac ttgaagatgt
     1321 atattaaagc taaatagaaa ttttatcaaa attctcctgt gttgatcatt gtacctgatg
     1381 tgactaacat aactgtgaaa ttacttttaa cccgaaatac attcttatta tgtatctgag
     1441 aattagggat acatctaaga caattctaac ttttttcatt aggtggcttt gcttctttgt
     1501 ggtatataat tgttagtggt aaagctgatt aacatc
//
