LOCUS       NM_173757               1849 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus mitochondrial ribosomal protein S27 (Mrps27), mRNA.
ACCESSION   NM_173757
VERSION     NM_173757.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1849)
  AUTHORS   Wang,Y., Yasmin,L., Li,L., Gao,P., Xu,X., Sun,X. and Godbout,R.
  TITLE     DDX1 vesicles control calcium-dependent mitochondrial activity in
            mouse embryos
  JOURNAL   Nat Commun 13 (1), 3794 (2022)
   PUBMED   35778392
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1849)
  AUTHORS   Cheong,A., Lingutla,R. and Mager,J.
  TITLE     Expression analysis of mammalian mitochondrial ribosomal protein
            genes
  JOURNAL   Gene Expr Patterns 38, 119147 (2020)
   PUBMED   32987154
REFERENCE   3  (bases 1 to 1849)
  AUTHORS   Shi,Z., Xu,S., Xing,S., Yao,K., Zhang,L., Xue,L., Zhou,P., Wang,M.,
            Yan,G., Yang,P., Liu,J., Hu,Z. and Lan,F.
  TITLE     Mettl17, a regulator of mitochondrial ribosomal RNA modifications,
            is required for the translation of mitochondrial coding genes
  JOURNAL   FASEB J 33 (11), 13040-13050 (2019)
   PUBMED   31487196
REFERENCE   4  (bases 1 to 1849)
  AUTHORS   Zurkirchen,L., Varum,S., Giger,S., Klug,A., Hausel,J., Bossart,R.,
            Zemke,M., Cantu,C., Atak,Z.K., Zamboni,N., Basler,K. and Sommer,L.
  TITLE     Yin Yang 1 sustains biosynthetic demands during brain development
            in a stage-specific manner
  JOURNAL   Nat Commun 10 (1), 2192 (2019)
   PUBMED   31097699
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1849)
  AUTHORS   Richman,T.R., Spahr,H., Ermer,J.A., Davies,S.M., Viola,H.M.,
            Bates,K.A., Papadimitriou,J., Hool,L.C., Rodger,J., Larsson,N.G.,
            Rackham,O. and Filipovska,A.
  TITLE     Loss of the RNA-binding protein TACO1 causes late-onset
            mitochondrial dysfunction in mice
  JOURNAL   Nat Commun 7, 11884 (2016)
   PUBMED   27319982
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1849)
  AUTHORS   Greber,B.J. and Ban,N.
  TITLE     Structure and Function of the Mitochondrial Ribosome
  JOURNAL   Annu Rev Biochem 85, 103-132 (2016)
   PUBMED   27023846
  REMARK    Review article
REFERENCE   7  (bases 1 to 1849)
  AUTHORS   Amunts,A., Brown,A., Toots,J., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Ribosome. The structure of the human mitochondrial ribosome
  JOURNAL   Science 348 (6230), 95-98 (2015)
   PUBMED   25838379
REFERENCE   8  (bases 1 to 1849)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   9  (bases 1 to 1849)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK076008.1, AK087686.1 and AA461997.1.
            
            On Aug 5, 2004 this sequence version replaced NM_173757.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK076008.1, AK087686.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                AK076008.1         1-10
            11-40               AK087686.1         7-36
            41-258              AK076008.1         40-257
            259-385             AK087686.1         255-381
            386-1848            AK076008.1         385-1847
            1849-1849           AA461997.1         338-338
FEATURES             Location/Qualifiers
     source          1..1849
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 52.83 cM"
     gene            1..1849
                     /gene="Mrps27"
                     /gene_synonym="2610028H14Rik"
                     /note="mitochondrial ribosomal protein S27"
                     /db_xref="GeneID:218506"
                     /db_xref="MGI:MGI:1919064"
     exon            1..90
                     /gene="Mrps27"
                     /gene_synonym="2610028H14Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             18..1265
                     /gene="Mrps27"
                     /gene_synonym="2610028H14Rik"
                     /note="28S ribosomal protein S27, mitochondrial; S27mt;
                     MRP-S27"
                     /codon_start=1
                     /product="small ribosomal subunit protein mS27"
                     /protein_id="NP_776118.2"
                     /db_xref="CCDS:CCDS26722.1"
                     /db_xref="GeneID:218506"
                     /db_xref="MGI:MGI:1919064"
                     /translation="MAAPMVRCGMLLARRLDASRLCLAGKRCLLSAAYVDSHQWEARE
                     KEEYHLADLASLMDKAYERKLPVSSLSISRFVDNIASREDLDSAEYYLYKFRHSPNCW
                     YLRDWTIHSWIRQCLKYGAQDKALYTLVNKVQYGIFPDNFTFNLLMDYFIKKGNYKDA
                     LSVVFEIMMQEAFDVPSTQFLSLYVLYRCLAEKTELTWEEERDFGASLLLSGLKQRNT
                     VGLSSQLYGYALLGKVELQRGVRAVYHGMPLMWTPGYLDRALQVMERVASSPEDLKLG
                     REVLDVLDGVLKVVTSPDVQTSEAQPQEGEDGLGSANLVEQLDTEEPEQSKLPRYLER
                     FQASRSKLQELNRVESESLLTLTTQLVKEKLPACEAEDLATYEQKLREWHLERVQLIQ
                     REQEQREKAKQEYQALSAAEKAA"
     exon            91..168
                     /gene="Mrps27"
                     /gene_synonym="2610028H14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            169..239
                     /gene="Mrps27"
                     /gene_synonym="2610028H14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            240..298
                     /gene="Mrps27"
                     /gene_synonym="2610028H14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            299..413
                     /gene="Mrps27"
                     /gene_synonym="2610028H14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            414..492
                     /gene="Mrps27"
                     /gene_synonym="2610028H14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            493..608
                     /gene="Mrps27"
                     /gene_synonym="2610028H14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            609..711
                     /gene="Mrps27"
                     /gene_synonym="2610028H14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            712..854
                     /gene="Mrps27"
                     /gene_synonym="2610028H14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            855..1025
                     /gene="Mrps27"
                     /gene_synonym="2610028H14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1026..1848
                     /gene="Mrps27"
                     /gene_synonym="2610028H14Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1830..1835
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrps27"
                     /gene_synonym="2610028H14Rik"
                     /note="putative"
     polyA_site      1848
                     /gene="Mrps27"
                     /gene_synonym="2610028H14Rik"
                     /note="putative"
ORIGIN      
        1 acttggtgcg ctccaagatg gcggctccca tggtgcggtg tgggatgctc ctggctcggc
       61 gactagacgc gtctcgcctt tgcctcgcag gtaaaagatg cctgctttct gcagcgtacg
      121 tggacagcca ccagtgggaa gccagagaga aggaggaata ccatctggct gatcttgcat
      181 ccttaatgga caaagcgtat gaaagaaaat tgcctgttag ttctttatca atatcacggt
      241 ttgtggacaa cattgcatcc cgagaagatc tagattctgc agagtactat ctttacaaat
      301 ttcgacacag tcccaactgc tggtacctaa gagactggac catccacagc tggattagac
      361 agtgtctgaa atacggagca caagacaaag ccttgtatac acttgttaat aaggttcagt
      421 atggaatttt tccagataac tttacattca acttactgat ggattatttc ataaagaaag
      481 gaaattacaa agatgcttta tccgtggttt ttgagatcat gatgcaagaa gcctttgacg
      541 tgccgtccac ccagtttctc tccctctatg ttttataccg ttgcctagca gagaagacgg
      601 agctcacatg ggaagaagaa agagactttg gggcgtccct cttgctttct ggcctgaaac
      661 aaaggaacac agtgggcctg agttcccagc tgtatggcta tgcacttctc gggaaggtgg
      721 aactgcagcg tggggtgcgg gctgtatacc acggcatgcc tctgatgtgg acaccaggct
      781 acctcgacag agccctccaa gtgatggaga gggtggcctc ctcccctgaa gacctcaagc
      841 tgggtagaga agtgctcgat gtgctggatg gagtcctgaa ggtggtgacg tctccagatg
      901 tccagacttc agaggcacag cctcaggaag gtgaagatgg cttgggctca gcaaacctgg
      961 tggagcagct agacactgag gaaccagaac agtccaagct tccccgatac ctcgagcgct
     1021 ttcaggcctc tcggtctaaa ctgcaggagc tgaacagagt tgagtctgaa agtcttttga
     1081 ctctgaccac ccagcttgta aaagaaaaac tccccgcctg tgaggccgag gacctggcca
     1141 cctacgagca gaaactccgt gagtggcacc tggagcgggt gcagttgatc cagagggagc
     1201 aggaacagag ggagaaggcc aagcaagagt accaggcgct gagtgcggca gagaaagcag
     1261 cctgaagttc tgtgagccac ctcagtgttc agccaggaca gcatggggct ccgccgctac
     1321 tgtccagttc ttttcttaca ggaagctgtg catagcctga aaacaaggat ggctctatgc
     1381 caagacactg tctgcccatc tagatgtcaa gggccctgaa ctaagtgaca aacggttggg
     1441 ctgaagcccc cacacagtgg agtcctgggt gcagactggg aatatcgggt gagcgtgacg
     1501 ggaagctata gctgaagggt cggctctgca gcacgggtgt ttgaatgatt tcctgccctt
     1561 ggccatgtgc atggagcacc gagcttcatg accaggtgct ggtagactca gaaccaccca
     1621 cgttccagaa ccgggtgctt gctcctttca cccgcttcca ggactcagca ccagtggcca
     1681 catgacctgc tgtcagtgtg acacatttcc actgttaaca ctggtctcat attctccctg
     1741 tgcatatgtg ccatatatag ctggcacctt catggtctgt ccccttccca tcactgctca
     1801 gaagcagcct tttgtatacc tgcctcccca ataaatccta cccatgtga
//
