LOCUS       NM_024174               1348 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus mitochondrial ribosomal protein S23 (Mrps23),
            transcript variant 1, mRNA.
ACCESSION   NM_024174
VERSION     NM_024174.6
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1348)
  AUTHORS   Cheong,A., Lingutla,R. and Mager,J.
  TITLE     Expression analysis of mammalian mitochondrial ribosomal protein
            genes
  JOURNAL   Gene Expr Patterns 38, 119147 (2020)
   PUBMED   32987154
REFERENCE   2  (bases 1 to 1348)
  AUTHORS   Greber,B.J. and Ban,N.
  TITLE     Structure and Function of the Mitochondrial Ribosome
  JOURNAL   Annu Rev Biochem 85, 103-132 (2016)
   PUBMED   27023846
  REMARK    Review article
REFERENCE   3  (bases 1 to 1348)
  AUTHORS   Amunts,A., Brown,A., Toots,J., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Ribosome. The structure of the human mitochondrial ribosome
  JOURNAL   Science 348 (6230), 95-98 (2015)
   PUBMED   25838379
REFERENCE   4  (bases 1 to 1348)
  AUTHORS   Combes,A.N., Lesieur,E., Harley,V.R., Sinclair,A.H., Little,M.H.,
            Wilhelm,D. and Koopman,P.
  TITLE     Three-dimensional visualization of testis cord morphogenesis, a
            novel tubulogenic mechanism in development
  JOURNAL   Dev Dyn 238 (5), 1033-1041 (2009)
   PUBMED   19334288
REFERENCE   5  (bases 1 to 1348)
  AUTHORS   Carninci,P., Waki,K., Shiraki,T., Konno,H., Shibata,K., Itoh,M.,
            Aizawa,K., Arakawa,T., Ishii,Y., Sasaki,D., Bono,H., Kondo,S.,
            Sugahara,Y., Saito,R., Osato,N., Fukuda,S., Sato,K., Watahiki,A.,
            Hirozane-Kishikawa,T., Nakamura,M., Shibata,Y., Yasunishi,A.,
            Kikuchi,N., Yoshiki,A., Kusakabe,M., Gustincich,S., Beisel,K.,
            Pavan,W., Aidinis,V., Nakagawara,A., Held,W.A., Iwata,H., Kono,T.,
            Nakauchi,H., Lyons,P., Wells,C., Hume,D.A., Fagiolini,M.,
            Hensch,T.K., Brinkmeier,M., Camper,S., Hirota,J., Mombaerts,P.,
            Muramatsu,M., Okazaki,Y., Kawai,J. and Hayashizaki,Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
REFERENCE   6  (bases 1 to 1348)
  AUTHORS   Koc,E.C., Burkhart,W., Blackburn,K., Moseley,A., Koc,H. and
            Spremulli,L.L.
  TITLE     A proteomics approach to the identification of mammalian
            mitochondrial small subunit ribosomal proteins
  JOURNAL   J Biol Chem 275 (42), 32585-32591 (2000)
   PUBMED   10938081
REFERENCE   7  (bases 1 to 1348)
  AUTHORS   Brady,K.P., Rowe,L.B., Her,H., Stevens,T.J., Eppig,J.,
            Sussman,D.J., Sikela,J. and Beier,D.R.
  TITLE     Genetic mapping of 262 loci derived from expressed sequences in a
            murine interspecific cross using single-strand conformational
            polymorphism analysis
  JOURNAL   Genome Res 7 (11), 1085-1093 (1997)
   PUBMED   9371744
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY238199.1, AK014375.2 and AW121224.1.
            
            On Mar 30, 2014 this sequence version replaced NM_024174.5.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC019980.1, AK168277.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-31                BY238199.1         4-34
            32-1184             AK014375.2         2-1154
            1185-1348           AW121224.1         1-164               c
FEATURES             Location/Qualifiers
     source          1..1348
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 52.4 cM"
     gene            1..1348
                     /gene="Mrps23"
                     /gene_synonym="D11Bwg1153e; MRP-S23; Rpms23; S23mt"
                     /note="mitochondrial ribosomal protein S23"
                     /db_xref="GeneID:64656"
                     /db_xref="MGI:MGI:1928138"
     exon            1..98
                     /gene="Mrps23"
                     /gene_synonym="D11Bwg1153e; MRP-S23; Rpms23; S23mt"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..588
                     /gene="Mrps23"
                     /gene_synonym="D11Bwg1153e; MRP-S23; Rpms23; S23mt"
                     /note="isoform a is encoded by transcript variant 1; 28S
                     ribosomal protein S23, mitochondrial; small ribosomal
                     subunit protein mS23"
                     /codon_start=1
                     /product="small ribosomal subunit protein mS23 isoform a"
                     /protein_id="NP_077136.2"
                     /db_xref="CCDS:CCDS25227.1"
                     /db_xref="GeneID:64656"
                     /db_xref="MGI:MGI:1928138"
                     /translation="MAGSRLETVGSVFSRTRDLMRAGVLKEKPLWYDIYKAFPPLREP
                     VFRRPRLRYGKAKADIQDIFYQEDQIRAKFFATYGSGQKAFDLFNPNFKSTCQRFVEK
                     YTELQNLGETDEEKLFVETGKALLAEGIILRRVREARTVSVRLQASSEGHEPQEDDDL
                     AQRGQVKQEPETAPSPP"
     exon            99..269
                     /gene="Mrps23"
                     /gene_synonym="D11Bwg1153e; MRP-S23; Rpms23; S23mt"
                     /inference="alignment:Splign:2.1.0"
     exon            270..347
                     /gene="Mrps23"
                     /gene_synonym="D11Bwg1153e; MRP-S23; Rpms23; S23mt"
                     /inference="alignment:Splign:2.1.0"
     exon            348..474
                     /gene="Mrps23"
                     /gene_synonym="D11Bwg1153e; MRP-S23; Rpms23; S23mt"
                     /inference="alignment:Splign:2.1.0"
     exon            475..1332
                     /gene="Mrps23"
                     /gene_synonym="D11Bwg1153e; MRP-S23; Rpms23; S23mt"
                     /inference="alignment:Splign:2.1.0"
     regulatory      765..770
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrps23"
                     /gene_synonym="D11Bwg1153e; MRP-S23; Rpms23; S23mt"
                     /note="hexamer: AATAAA"
     polyA_site      796
                     /gene="Mrps23"
                     /gene_synonym="D11Bwg1153e; MRP-S23; Rpms23; S23mt"
     regulatory      1309..1314
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrps23"
                     /gene_synonym="D11Bwg1153e; MRP-S23; Rpms23; S23mt"
                     /note="hexamer: AATAAA"
     polyA_site      1332
                     /gene="Mrps23"
                     /gene_synonym="D11Bwg1153e; MRP-S23; Rpms23; S23mt"
                     /note="major polyA site"
ORIGIN      
        1 ttgctgccgc ttccgcttcc ggtaacagcc cgaggctttc tagcccaagt ggccatggcg
       61 gggagccggc tggagacggt ggggagcgtg ttctcccgga cgagggatct gatgcgggcc
      121 ggggtgttga aagagaagcc actgtggtat gacatatata aggcctttcc acccctgaga
      181 gagcctgtct tccgaaggcc ccgcttgcga tacggcaaag ccaaagctga catccaggac
      241 atcttttacc aggaggatca gattcgagcg aaattctttg caacctatgg atctggtcag
      301 aaagcttttg atctcttcaa cccaaacttc aagtctacct gtcagcggtt tgtggagaag
      361 tacacagagc ttcagaatct tggagaaaca gatgaagaga agttatttgt agaaacgggg
      421 aaggctctgt tggcagaagg catcatttta agaagagttc gagaagcaag gactgtcagc
      481 gtgagactcc aagcttcatc agaaggacat gagcctcagg aagacgatga cctggcgcag
      541 cgggggcagg tgaagcagga gccagaaaca gccccgtccc ctccctgagg cccttcagcg
      601 catgagcacg cccatcaccg ctggcccaag ctgatggact ctgatggcct ccatctctca
      661 ggcacgtgtg ccttctctta gtccctgttt tcgggatgtt atgaatctca gtactgtggt
      721 ttgaaagcac cagctttgtg aacttttatt tcaagacatg gttaaataaa gggttctcca
      781 atgcttacaa agtaaattta ctttgaaact gtaaataaca ccaggaagcc tttaaaggtg
      841 ccttgtgctg gccttgggct gccggcatct gaactctttg ggcttctcgt ctggatccct
      901 cagaatccta cttggccaca aggtccggtc cctcggccgt gtctgcgggt ggtgtttgta
      961 ctttttttct gtagagctgt tgactgcatc ctgacaggca cagcagaggc acagccaact
     1021 cctgctgcag taagaccgag tgcctgtttg atgtggacga agatcacacc cagtccttgg
     1081 atgtcacggg ttgggttcat tgctcttgag atgatcagca tgggcacaca gctcataggc
     1141 tgcctagaaa ttgtttggtg actgaataaa tgaccacacc tagctaaaga ctgacgtttt
     1201 cctagtcact ggatttccaa gatggcaggg gtaggggtct gattcaggtg gtcttcccca
     1261 caaacatcct gccgccctgg tactgcttcc ttgtgttgtg ttacaccaaa taaatgcgat
     1321 atcctgttgt gaaaaaaaaa aaaaaaaa
//
