LOCUS       NM_025878               1129 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus mitochondrial ribosomal protein S18B (Mrps18b),
            transcript variant 1, mRNA.
ACCESSION   NM_025878
VERSION     NM_025878.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1129)
  AUTHORS   Cheong,A., Lingutla,R. and Mager,J.
  TITLE     Expression analysis of mammalian mitochondrial ribosomal protein
            genes
  JOURNAL   Gene Expr Patterns 38, 119147 (2020)
   PUBMED   32987154
REFERENCE   2  (bases 1 to 1129)
  AUTHORS   Mushtaq,M., Kovalevska,L., Darekar,S., Abramsson,A., Zetterberg,H.,
            Kashuba,V., Klein,G., Arsenian-Henriksson,M. and Kashuba,E.
  TITLE     Cell stemness is maintained upon concurrent expression of RB and
            the mitochondrial ribosomal protein S18-2
  JOURNAL   Proc Natl Acad Sci U S A 117 (27), 15673-15683 (2020)
   PUBMED   32571933
  REMARK    GeneRIF: Cell stemness is maintained upon concurrent expression of
            RB and the mitochondrial ribosomal protein S18-2.
REFERENCE   3  (bases 1 to 1129)
  AUTHORS   Lavado,A., Park,J.Y., Pare,J., Finkelstein,D., Pan,H., Xu,B.,
            Fan,Y., Kumar,R.P., Neale,G., Kwak,Y.D., McKinnon,P.J.,
            Johnson,R.L. and Cao,X.
  TITLE     The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and
            Controls Neural Progenitor Number
  JOURNAL   Dev Cell 47 (5), 576-591 (2018)
   PUBMED   30523785
REFERENCE   4  (bases 1 to 1129)
  AUTHORS   Greber,B.J. and Ban,N.
  TITLE     Structure and Function of the Mitochondrial Ribosome
  JOURNAL   Annu Rev Biochem 85, 103-132 (2016)
   PUBMED   27023846
  REMARK    Review article
REFERENCE   5  (bases 1 to 1129)
  AUTHORS   Amunts,A., Brown,A., Toots,J., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Ribosome. The structure of the human mitochondrial ribosome
  JOURNAL   Science 348 (6230), 95-98 (2015)
   PUBMED   25838379
REFERENCE   6  (bases 1 to 1129)
  AUTHORS   Suzuki,T., Terasaki,M., Takemoto-Hori,C., Hanada,T., Ueda,T.,
            Wada,A. and Watanabe,K.
  TITLE     Proteomic analysis of the mammalian mitochondrial ribosome.
            Identification of protein components in the 28 S small subunit
  JOURNAL   J Biol Chem 276 (35), 33181-33195 (2001)
   PUBMED   11402041
REFERENCE   7  (bases 1 to 1129)
  AUTHORS   Cavdar Koc,E., Burkhart,W., Blackburn,K., Moseley,A. and
            Spremulli,L.L.
  TITLE     The small subunit of the mammalian mitochondrial ribosome.
            Identification of the full complement of ribosomal proteins present
  JOURNAL   J Biol Chem 276 (22), 19363-19374 (2001)
   PUBMED   11279123
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CR974451.9.
            
            On Mar 19, 2018 this sequence version replaced NM_025878.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK167067.1, DV649021.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-149               CR974451.9         140687-140835       c
            150-258             CR974451.9         139091-139199       c
            259-356             CR974451.9         138887-138984       c
            357-425             CR974451.9         138729-138797       c
            426-492             CR974451.9         136733-136799       c
            493-552             CR974451.9         135814-135873       c
            553-1129            CR974451.9         134775-135351       c
FEATURES             Location/Qualifiers
     source          1..1129
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 18.76 cM"
     gene            1..1129
                     /gene="Mrps18b"
                     /gene_synonym="2400002C15Rik; MRP-S18-2; S18mt-b"
                     /note="mitochondrial ribosomal protein S18B"
                     /db_xref="GeneID:66973"
                     /db_xref="MGI:MGI:1914223"
     exon            1..149
                     /gene="Mrps18b"
                     /gene_synonym="2400002C15Rik; MRP-S18-2; S18mt-b"
                     /inference="alignment:Splign:2.1.0"
     CDS             78..842
                     /gene="Mrps18b"
                     /gene_synonym="2400002C15Rik; MRP-S18-2; S18mt-b"
                     /note="isoform 1 is encoded by transcript variant 1; 28S
                     ribosomal protein S18b, mitochondrial; 28S ribosomal
                     protein S18-2, mitochondrial; small ribosomal subunit
                     protein mS40"
                     /codon_start=1
                     /product="small ribosomal subunit protein mS40 isoform 1"
                     /protein_id="NP_080154.1"
                     /db_xref="CCDS:CCDS28712.1"
                     /db_xref="GeneID:66973"
                     /db_xref="MGI:MGI:1914223"
                     /translation="MAAPLRHTLLKLVPTLLRSSYVAQVPLQTLCTRGPPEEDAPSSL
                     PVSPYESEPWKYLDSEEYHNRYGSRPVWADYRRNHKGGVPPQRTRKTCIRNNKVAGNP
                     CPICRDHKLHVDFRNVKLLEQFVCAHTGIIFHAPYTGVCMKQHKKLTQAIQKARECGL
                     LSYYVPQVEPRDADFGTVHGAVSVTPPAPTLLSGEPWYPWYSWQQPPERELSRLRRLY
                     QGNLLEESGPPPESMPEMPTTPPAESSIEQPGSQSA"
     exon            150..258
                     /gene="Mrps18b"
                     /gene_synonym="2400002C15Rik; MRP-S18-2; S18mt-b"
                     /inference="alignment:Splign:2.1.0"
     exon            259..356
                     /gene="Mrps18b"
                     /gene_synonym="2400002C15Rik; MRP-S18-2; S18mt-b"
                     /inference="alignment:Splign:2.1.0"
     exon            357..425
                     /gene="Mrps18b"
                     /gene_synonym="2400002C15Rik; MRP-S18-2; S18mt-b"
                     /inference="alignment:Splign:2.1.0"
     exon            426..492
                     /gene="Mrps18b"
                     /gene_synonym="2400002C15Rik; MRP-S18-2; S18mt-b"
                     /inference="alignment:Splign:2.1.0"
     exon            493..552
                     /gene="Mrps18b"
                     /gene_synonym="2400002C15Rik; MRP-S18-2; S18mt-b"
                     /inference="alignment:Splign:2.1.0"
     exon            553..1129
                     /gene="Mrps18b"
                     /gene_synonym="2400002C15Rik; MRP-S18-2; S18mt-b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccttggccca ccctagtgcg tgtcccgagc atgcgcagtc gctcttccgg caggccgtac
       61 gtccggtgtg cgtcaagatg gctgccccct tgcggcacac gcttctaaag ctggttccta
      121 cactcttacg aagttcctat gtagctcagg ttcccctcca gactctttgc accagaggcc
      181 ctcctgaaga agatgctcca tcctcgcttc ccgtttcccc atatgagagc gagccttgga
      241 agtacctgga ttcagaagaa taccacaacc gctatggctc tcgccctgtt tgggctgact
      301 accgccgcaa ccacaaaggt ggtgtgccac cacagcggac ccgaaagaca tgtattcgta
      361 acaataaagt tgctgggaat ccttgcccaa tctgccggga tcacaagttg catgttgact
      421 ttaggaatgt gaagctcttg gaacagtttg tctgtgcaca cacgggtatc atctttcacg
      481 ccccatacac aggggtctgt atgaagcagc acaagaagct gacccaggcc atccagaaag
      541 ccagggagtg tggtcttctc agttactacg tcccccaggt tgagccccgg gatgctgact
      601 ttggtactgt gcatggagct gtcagtgtga ctccaccagc ccccacactg ttgtcaggtg
      661 aaccttggta cccatggtac agctggcaac agccaccaga gagagagctg tctcgccttc
      721 gccgactcta tcaaggaaat ctcctagaag aaagtggccc gccacctgag tcgatgccag
      781 agatgcccac tacaccacca gcagaatcct ccattgagca gccaggctcc cagagtgctt
      841 agaacttgtg acctggggaa gtcagaccaa gggagtactg tctagggcta cgtggtatcc
      901 tgtgtcctgc aaagggttct gttttgtgac agtggcagac cctataggga actggctggc
      961 atgaagagaa caaagcacat ttgacgttga gggggactag atgtttatgg gtaactggtg
     1021 aggacttaca tataaactgg agactcttgt gtatgccctt gatggtgtgt ccctgattta
     1081 aacctcctgg ctcagctttt atacaataaa gctgtgtctc ttcacccgt
//
