LOCUS       NM_001361454            1002 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus mitochondrial ribosomal protein S18B (Mrps18b),
            transcript variant 4, mRNA.
ACCESSION   NM_001361454
VERSION     NM_001361454.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1002)
  AUTHORS   Cheong,A., Lingutla,R. and Mager,J.
  TITLE     Expression analysis of mammalian mitochondrial ribosomal protein
            genes
  JOURNAL   Gene Expr Patterns 38, 119147 (2020)
   PUBMED   32987154
REFERENCE   2  (bases 1 to 1002)
  AUTHORS   Mushtaq,M., Kovalevska,L., Darekar,S., Abramsson,A., Zetterberg,H.,
            Kashuba,V., Klein,G., Arsenian-Henriksson,M. and Kashuba,E.
  TITLE     Cell stemness is maintained upon concurrent expression of RB and
            the mitochondrial ribosomal protein S18-2
  JOURNAL   Proc Natl Acad Sci U S A 117 (27), 15673-15683 (2020)
   PUBMED   32571933
  REMARK    GeneRIF: Cell stemness is maintained upon concurrent expression of
            RB and the mitochondrial ribosomal protein S18-2.
REFERENCE   3  (bases 1 to 1002)
  AUTHORS   Lavado,A., Park,J.Y., Pare,J., Finkelstein,D., Pan,H., Xu,B.,
            Fan,Y., Kumar,R.P., Neale,G., Kwak,Y.D., McKinnon,P.J.,
            Johnson,R.L. and Cao,X.
  TITLE     The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and
            Controls Neural Progenitor Number
  JOURNAL   Dev Cell 47 (5), 576-591 (2018)
   PUBMED   30523785
REFERENCE   4  (bases 1 to 1002)
  AUTHORS   Greber,B.J. and Ban,N.
  TITLE     Structure and Function of the Mitochondrial Ribosome
  JOURNAL   Annu Rev Biochem 85, 103-132 (2016)
   PUBMED   27023846
  REMARK    Review article
REFERENCE   5  (bases 1 to 1002)
  AUTHORS   Amunts,A., Brown,A., Toots,J., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Ribosome. The structure of the human mitochondrial ribosome
  JOURNAL   Science 348 (6230), 95-98 (2015)
   PUBMED   25838379
REFERENCE   6  (bases 1 to 1002)
  AUTHORS   Suzuki,T., Terasaki,M., Takemoto-Hori,C., Hanada,T., Ueda,T.,
            Wada,A. and Watanabe,K.
  TITLE     Proteomic analysis of the mammalian mitochondrial ribosome.
            Identification of protein components in the 28 S small subunit
  JOURNAL   J Biol Chem 276 (35), 33181-33195 (2001)
   PUBMED   11402041
REFERENCE   7  (bases 1 to 1002)
  AUTHORS   Cavdar Koc,E., Burkhart,W., Blackburn,K., Moseley,A. and
            Spremulli,L.L.
  TITLE     The small subunit of the mammalian mitochondrial ribosome.
            Identification of the full complement of ribosomal proteins present
  JOURNAL   J Biol Chem 276 (22), 19363-19374 (2001)
   PUBMED   11279123
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CR974451.9.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BF022231.1, AV573478.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135, SAMN01164140
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-149               CR974451.9         140687-140835       c
            150-258             CR974451.9         139091-139199       c
            259-356             CR974451.9         138887-138984       c
            357-425             CR974451.9         138729-138797       c
            426-1002            CR974451.9         134775-135351       c
FEATURES             Location/Qualifiers
     source          1..1002
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 18.76 cM"
     gene            1..1002
                     /gene="Mrps18b"
                     /gene_synonym="2400002C15Rik; MRP-S18-2; S18mt-b"
                     /note="mitochondrial ribosomal protein S18B"
                     /db_xref="GeneID:66973"
                     /db_xref="MGI:MGI:1914223"
     exon            1..149
                     /gene="Mrps18b"
                     /gene_synonym="2400002C15Rik; MRP-S18-2; S18mt-b"
                     /inference="alignment:Splign:2.1.0"
     CDS             78..503
                     /gene="Mrps18b"
                     /gene_synonym="2400002C15Rik; MRP-S18-2; S18mt-b"
                     /note="isoform 4 is encoded by transcript variant 4; 28S
                     ribosomal protein S18b, mitochondrial; 28S ribosomal
                     protein S18-2, mitochondrial; small ribosomal subunit
                     protein mS40"
                     /codon_start=1
                     /product="small ribosomal subunit protein mS40 isoform 4"
                     /protein_id="NP_001348383.1"
                     /db_xref="GeneID:66973"
                     /db_xref="MGI:MGI:1914223"
                     /translation="MAAPLRHTLLKLVPTLLRSSYVAQVPLQTLCTRGPPEEDAPSSL
                     PVSPYESEPWKYLDSEEYHNRYGSRPVWADYRRNHKGGVPPQRTRKTCIRNNKVAGNP
                     CPICRDHKLHVDFRVFSVTTSPRLSPGMLTLVLCMELSV"
     exon            150..258
                     /gene="Mrps18b"
                     /gene_synonym="2400002C15Rik; MRP-S18-2; S18mt-b"
                     /inference="alignment:Splign:2.1.0"
     exon            259..356
                     /gene="Mrps18b"
                     /gene_synonym="2400002C15Rik; MRP-S18-2; S18mt-b"
                     /inference="alignment:Splign:2.1.0"
     exon            357..425
                     /gene="Mrps18b"
                     /gene_synonym="2400002C15Rik; MRP-S18-2; S18mt-b"
                     /inference="alignment:Splign:2.1.0"
     exon            426..1002
                     /gene="Mrps18b"
                     /gene_synonym="2400002C15Rik; MRP-S18-2; S18mt-b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccttggccca ccctagtgcg tgtcccgagc atgcgcagtc gctcttccgg caggccgtac
       61 gtccggtgtg cgtcaagatg gctgccccct tgcggcacac gcttctaaag ctggttccta
      121 cactcttacg aagttcctat gtagctcagg ttcccctcca gactctttgc accagaggcc
      181 ctcctgaaga agatgctcca tcctcgcttc ccgtttcccc atatgagagc gagccttgga
      241 agtacctgga ttcagaagaa taccacaacc gctatggctc tcgccctgtt tgggctgact
      301 accgccgcaa ccacaaaggt ggtgtgccac cacagcggac ccgaaagaca tgtattcgta
      361 acaataaagt tgctgggaat ccttgcccaa tctgccggga tcacaagttg catgttgact
      421 ttagggtctt ctcagttact acgtccccca ggttgagccc cgggatgctg actttggtac
      481 tgtgcatgga gctgtcagtg tgactccacc agcccccaca ctgttgtcag gtgaaccttg
      541 gtacccatgg tacagctggc aacagccacc agagagagag ctgtctcgcc ttcgccgact
      601 ctatcaagga aatctcctag aagaaagtgg cccgccacct gagtcgatgc cagagatgcc
      661 cactacacca ccagcagaat cctccattga gcagccaggc tcccagagtg cttagaactt
      721 gtgacctggg gaagtcagac caagggagta ctgtctaggg ctacgtggta tcctgtgtcc
      781 tgcaaagggt tctgttttgt gacagtggca gaccctatag ggaactggct ggcatgaaga
      841 gaacaaagca catttgacgt tgagggggac tagatgttta tgggtaactg gtgaggactt
      901 acatataaac tggagactct tgtgtatgcc cttgatggtg tgtccctgat ttaaacctcc
      961 tggctcagct tttatacaat aaagctgtgt ctcttcaccc gt
//
