LOCUS       NM_001347380             873 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus mitochondrial ribosomal protein S18B (Mrps18b),
            transcript variant 2, mRNA.
ACCESSION   NM_001347380 XM_006524807
VERSION     NM_001347380.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 873)
  AUTHORS   Cheong,A., Lingutla,R. and Mager,J.
  TITLE     Expression analysis of mammalian mitochondrial ribosomal protein
            genes
  JOURNAL   Gene Expr Patterns 38, 119147 (2020)
   PUBMED   32987154
REFERENCE   2  (bases 1 to 873)
  AUTHORS   Mushtaq,M., Kovalevska,L., Darekar,S., Abramsson,A., Zetterberg,H.,
            Kashuba,V., Klein,G., Arsenian-Henriksson,M. and Kashuba,E.
  TITLE     Cell stemness is maintained upon concurrent expression of RB and
            the mitochondrial ribosomal protein S18-2
  JOURNAL   Proc Natl Acad Sci U S A 117 (27), 15673-15683 (2020)
   PUBMED   32571933
  REMARK    GeneRIF: Cell stemness is maintained upon concurrent expression of
            RB and the mitochondrial ribosomal protein S18-2.
REFERENCE   3  (bases 1 to 873)
  AUTHORS   Lavado,A., Park,J.Y., Pare,J., Finkelstein,D., Pan,H., Xu,B.,
            Fan,Y., Kumar,R.P., Neale,G., Kwak,Y.D., McKinnon,P.J.,
            Johnson,R.L. and Cao,X.
  TITLE     The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and
            Controls Neural Progenitor Number
  JOURNAL   Dev Cell 47 (5), 576-591 (2018)
   PUBMED   30523785
REFERENCE   4  (bases 1 to 873)
  AUTHORS   Greber,B.J. and Ban,N.
  TITLE     Structure and Function of the Mitochondrial Ribosome
  JOURNAL   Annu Rev Biochem 85, 103-132 (2016)
   PUBMED   27023846
  REMARK    Review article
REFERENCE   5  (bases 1 to 873)
  AUTHORS   Amunts,A., Brown,A., Toots,J., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Ribosome. The structure of the human mitochondrial ribosome
  JOURNAL   Science 348 (6230), 95-98 (2015)
   PUBMED   25838379
REFERENCE   6  (bases 1 to 873)
  AUTHORS   Suzuki,T., Terasaki,M., Takemoto-Hori,C., Hanada,T., Ueda,T.,
            Wada,A. and Watanabe,K.
  TITLE     Proteomic analysis of the mammalian mitochondrial ribosome.
            Identification of protein components in the 28 S small subunit
  JOURNAL   J Biol Chem 276 (35), 33181-33195 (2001)
   PUBMED   11402041
REFERENCE   7  (bases 1 to 873)
  AUTHORS   Cavdar Koc,E., Burkhart,W., Blackburn,K., Moseley,A. and
            Spremulli,L.L.
  TITLE     The small subunit of the mammalian mitochondrial ribosome.
            Identification of the full complement of ribosomal proteins present
  JOURNAL   J Biol Chem 276 (22), 19363-19374 (2001)
   PUBMED   11279123
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DV649021.1, AK076033.1 and BP770625.1.
            
            On Nov 24, 2016 this sequence version replaced XM_006524807.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK002554.1, AK076033.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-51                DV649021.1         1-51
            52-847              AK076033.1         2-797
            848-873             BP770625.1         20-45               c
FEATURES             Location/Qualifiers
     source          1..873
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 18.76 cM"
     gene            1..873
                     /gene="Mrps18b"
                     /gene_synonym="2400002C15Rik; MRP-S18-2; S18mt-b"
                     /note="mitochondrial ribosomal protein S18B"
                     /db_xref="GeneID:66973"
                     /db_xref="MGI:MGI:1914223"
     exon            1..149
                     /gene="Mrps18b"
                     /gene_synonym="2400002C15Rik; MRP-S18-2; S18mt-b"
                     /inference="alignment:Splign:2.1.0"
     CDS             78..566
                     /gene="Mrps18b"
                     /gene_synonym="2400002C15Rik; MRP-S18-2; S18mt-b"
                     /note="isoform 2 is encoded by transcript variant 2; 28S
                     ribosomal protein S18b, mitochondrial; 28S ribosomal
                     protein S18-2, mitochondrial; small ribosomal subunit
                     protein mS40"
                     /codon_start=1
                     /product="small ribosomal subunit protein mS40 isoform 2"
                     /protein_id="NP_001334309.1"
                     /db_xref="CCDS:CCDS84307.1"
                     /db_xref="GeneID:66973"
                     /db_xref="MGI:MGI:1914223"
                     /translation="MAAPLRHTLLKLVPTLLRSSYVAQNVKLLEQFVCAHTGIIFHAP
                     YTGVCMKQHKKLTQAIQKARECGLLSYYVPQVEPRDADFGTVHGAVSVTPPAPTLLSG
                     EPWYPWYSWQQPPERELSRLRRLYQGNLLEESGPPPESMPEMPTTPPAESSIEQPGSQ
                     SA"
     exon            150..216
                     /gene="Mrps18b"
                     /gene_synonym="2400002C15Rik; MRP-S18-2; S18mt-b"
                     /inference="alignment:Splign:2.1.0"
     exon            217..276
                     /gene="Mrps18b"
                     /gene_synonym="2400002C15Rik; MRP-S18-2; S18mt-b"
                     /inference="alignment:Splign:2.1.0"
     exon            277..853
                     /gene="Mrps18b"
                     /gene_synonym="2400002C15Rik; MRP-S18-2; S18mt-b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccttggccca ccctagtgcg tgtcccgagc atgcgcagtc gctcttccgg caggccgtac
       61 gtccggtgtg cgtcaagatg gctgccccct tgcggcacac gcttctaaag ctggttccta
      121 cactcttacg aagttcctat gtagctcaga atgtgaagct cttggaacag tttgtctgtg
      181 cacacacggg tatcatcttt cacgccccat acacaggggt ctgtatgaag cagcacaaga
      241 agctgaccca ggccatccag aaagccaggg agtgtggtct tctcagttac tacgtccccc
      301 aggttgagcc ccgggatgct gactttggta ctgtgcatgg agctgtcagt gtgactccac
      361 cagcccccac actgttgtca ggtgaacctt ggtacccatg gtacagctgg caacagccac
      421 cagagagaga gctgtctcgc cttcgccgac tctatcaagg aaatctccta gaagaaagtg
      481 gcccgccacc tgagtcgatg ccagagatgc ccactacacc accagcagaa tcctccattg
      541 agcagccagg ctcccagagt gcttagaact tgtgacctgg ggaagtcaga ccaagggagt
      601 actgtctagg gctacgtggt atcctgtgtc ctgcaaaggg ttctgttttg tgacagtggc
      661 agaccctata gggaactggc tggcatgaag agaacaaagc acatttgacg ttgaggggga
      721 ctagatgttt atgggtaact ggtgaggact tacatataaa ctggagactc ttgtgtatgc
      781 ccttgatggt gtgtccctga tttaaacctc ctggctcagc ttttatacaa taaagctgtg
      841 tctcttcacc cgtaaaaaaa aaaaaaaaaa aaa
//
