LOCUS       NM_025474               2015 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus mitochondrial ribosomal protein S14 (Mrps14),
            transcript variant 1, mRNA.
ACCESSION   NM_025474
VERSION     NM_025474.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2015)
  AUTHORS   Cheong,A., Lingutla,R. and Mager,J.
  TITLE     Expression analysis of mammalian mitochondrial ribosomal protein
            genes
  JOURNAL   Gene Expr Patterns 38, 119147 (2020)
   PUBMED   32987154
REFERENCE   2  (bases 1 to 2015)
  AUTHORS   Greber,B.J. and Ban,N.
  TITLE     Structure and Function of the Mitochondrial Ribosome
  JOURNAL   Annu Rev Biochem 85, 103-132 (2016)
   PUBMED   27023846
  REMARK    Review article
REFERENCE   3  (bases 1 to 2015)
  AUTHORS   Amunts,A., Brown,A., Toots,J., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Ribosome. The structure of the human mitochondrial ribosome
  JOURNAL   Science 348 (6230), 95-98 (2015)
   PUBMED   25838379
REFERENCE   4  (bases 1 to 2015)
  AUTHORS   Brower,C.S., Rosen,C.E., Jones,R.H., Wadas,B.C., Piatkov,K.I. and
            Varshavsky,A.
  TITLE     Liat1, an arginyltransferase-binding protein whose evolution among
            primates involved changes in the numbers of its 10-residue repeats
  JOURNAL   Proc Natl Acad Sci U S A 111 (46), E4936-E4945 (2014)
   PUBMED   25369936
REFERENCE   5  (bases 1 to 2015)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   6  (bases 1 to 2015)
  AUTHORS   Koc,E.C., Burkhart,W., Blackburn,K., Moseley,A., Koc,H. and
            Spremulli,L.L.
  TITLE     A proteomics approach to the identification of mammalian
            mitochondrial small subunit ribosomal proteins
  JOURNAL   J Biol Chem 275 (42), 32585-32591 (2000)
   PUBMED   10938081
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154873.6, AK010242.1 and AK083352.1.
            
            On Dec 16, 2016 this sequence version replaced NM_025474.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK083352.1, AK144195.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-41                AC154873.6         189822-189862
            42-900              AK010242.1         3-861
            901-1175            AC154873.6         194679-194953
            1176-2015           AK083352.1         1130-1969
FEATURES             Location/Qualifiers
     source          1..2015
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 69.59 cM"
     gene            1..2015
                     /gene="Mrps14"
                     /gene_synonym="1810032L21Rik; Rpms14"
                     /note="mitochondrial ribosomal protein S14"
                     /db_xref="GeneID:64659"
                     /db_xref="MGI:MGI:1928141"
     exon            1..97
                     /gene="Mrps14"
                     /gene_synonym="1810032L21Rik; Rpms14"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..439
                     /gene="Mrps14"
                     /gene_synonym="1810032L21Rik; Rpms14"
                     /EC_number="3.6.5.3"
                     /note="isoform 1 is encoded by transcript variant 1; 28S
                     ribosomal protein S14, mitochondrial; S14mt; MRP-S14;
                     small ribosomal subunit protein uS14m"
                     /codon_start=1
                     /product="small ribosomal subunit protein uS14m isoform 1"
                     /protein_id="NP_079750.1"
                     /db_xref="CCDS:CCDS15405.1"
                     /db_xref="GeneID:64659"
                     /db_xref="MGI:MGI:1928141"
                     /translation="MAASVLGSLLRTFRQAVPPSASGQVRGYYVDWRMLRDLKRRKMA
                     YEYADERLRINSLRKNTILPKDLQEMAGDEIAALPRDSCPVRIRNRCVMTSRPRGVKR
                     RWRLSRIVFRHLADHGLLSGVQRAIW"
     exon            98..256
                     /gene="Mrps14"
                     /gene_synonym="1810032L21Rik; Rpms14"
                     /inference="alignment:Splign:2.1.0"
     exon            257..2015
                     /gene="Mrps14"
                     /gene_synonym="1810032L21Rik; Rpms14"
                     /inference="alignment:Splign:2.1.0"
     regulatory      628..633
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrps14"
                     /gene_synonym="1810032L21Rik; Rpms14"
                     /note="hexamer: AATAAA"
     polyA_site      649
                     /gene="Mrps14"
                     /gene_synonym="1810032L21Rik; Rpms14"
                     /note="major polyA site"
     regulatory      879..884
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrps14"
                     /gene_synonym="1810032L21Rik; Rpms14"
                     /note="hexamer: AATAAA"
     polyA_site      898
                     /gene="Mrps14"
                     /gene_synonym="1810032L21Rik; Rpms14"
                     /note="major polyA site"
     regulatory      1247..1252
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrps14"
                     /gene_synonym="1810032L21Rik; Rpms14"
                     /note="hexamer: AACAAG"
     polyA_site      1270
                     /gene="Mrps14"
                     /gene_synonym="1810032L21Rik; Rpms14"
ORIGIN      
        1 acctgtttcc ggtgttgtac tgcggcggtg gttggctggc tgggcagaca acatggcggc
       61 gtccgtgcta ggctcgctgc tgcggacctt ccggcaggca gttcctccat cagcgtcagg
      121 tcaagttcga ggttactatg tagactggag aatgttgcgt gatttgaaga gacggaaaat
      181 ggcttatgaa tatgcagatg agaggcttcg gatcaattcg ctcagaaaga ataccatttt
      241 gccaaaggac cttcaggaaa tggctggtga tgaaattgct gcccttccac gggatagctg
      301 tcctgttaga atcagaaatc gctgtgttat gacatctcgc ccacgtggtg ttaagcgtcg
      361 ctggagactt agtcgcattg tcttccgcca cttagctgac cacgggctac tttctggagt
      421 ccagcgagcg atatggtaaa accatttcag aacctgccca gctgggcagt caatcctggc
      481 aggagactta agatcaaacc ctaggtctta caagggtcta gtatgtttag tctacttaac
      541 cctgagttaa attactttta cattttaaat aatgtggcta tttgtcattg aattgtcttt
      601 caactttaaa gcatagtaca agagtggaat aaacatattt tctgtgaaag tatggtcttt
      661 ccttcaagtt tgatgtttag tagcaaaata atatatattt ttggagtgat ttcacaaaat
      721 atttctagat gtcagatcta attgacaggt tgcttttcta tgttgtattc ctggactagt
      781 ttccctggtc tgcagttaca atcacttttt ggataacaat agacagagtt aaacaggata
      841 ttctaaatta tatttagggt caactttatg tgacagtgaa taaaagaact gctaaatagt
      901 tgtttcatct tttaaatttt ttcattactg cgtatggatg ttttcatgca tgcaaaccta
      961 tgttccacgt gggtgcctgg tgctggaggc cagaggaagg ccctgggttc caattacaaa
     1021 cagctgtgag ctaccacatt taaaccttac ctgttgcctg gagacttcga tatttcagtg
     1081 ctgatggttg cacgggatct gttttcatta aggattgtag gattttctaa ttctatcttt
     1141 gctgcatcct ttgggtgttt gttattattt ttttaaaaaa ctttccatat caacaattac
     1201 taaaacatgt ttctttgaca taaatgtgta attaattttc agagtaaaca agttgctata
     1261 ctactaaaaa tggaaaccaa tcattgttca tccctgtgaa ctttgaaatg tttatatatt
     1321 tggtgcatta gcccactctg cccattctta cccatgatca ttgtcctatt accagtggaa
     1381 gtcccttgac atctctatcc tgtaagtaag gttattcact atgttcttga ttgattactg
     1441 ttataacagc cagtatagtt cctgattaag acacctgtct ttagggctct tttagtagga
     1501 aatgtttaga gaccacaaga tacactaagg ttaactcata gccattaagt tgtcattgcc
     1561 ttgctaggaa ttttcatttt gtttcaagat ttttaattat gtgtatatgt atgtgtgggg
     1621 cagggggtga gtgcttgggg ggaccagagg tgtcagatac tagagctgga cttagtcttg
     1681 tgagccacat gggatgggtg ttgggaacag aactggggtt ccctttgaga gtggtataca
     1741 tcccttcagc cctagaaatg tgtttttatt ataagtaaaa catagtggta cctttatatt
     1801 aattctatat ttatgtatct tacataaaaa ttttaaatct tgggggctgg agggatggct
     1861 cagcagagag caagtactgt tcttccaaag gatcagagtt cagttcctag cacccatgag
     1921 ggacagctca taaccaactg taattcaact ccctgggaag tccaaaaaac ctctggcagc
     1981 ctccagcaac cacaatggcg attaactcaa gattt
//
