LOCUS       NM_178603               2103 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus mitochondrial ribosomal protein L50 (Mrpl50), mRNA.
ACCESSION   NM_178603
VERSION     NM_178603.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2103)
  AUTHORS   Cheong,A., Lingutla,R. and Mager,J.
  TITLE     Expression analysis of mammalian mitochondrial ribosomal protein
            genes
  JOURNAL   Gene Expr Patterns 38, 119147 (2020)
   PUBMED   32987154
REFERENCE   2  (bases 1 to 2103)
  AUTHORS   Greber,B.J. and Ban,N.
  TITLE     Structure and Function of the Mitochondrial Ribosome
  JOURNAL   Annu Rev Biochem 85, 103-132 (2016)
   PUBMED   27023846
  REMARK    Review article
REFERENCE   3  (bases 1 to 2103)
  AUTHORS   Brown,A., Amunts,A., Bai,X.C., Sugimoto,Y., Edwards,P.C.,
            Murshudov,G., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Structure of the large ribosomal subunit from human mitochondria
  JOURNAL   Science 346 (6210), 718-722 (2014)
   PUBMED   25278503
REFERENCE   4  (bases 1 to 2103)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   5  (bases 1 to 2103)
  AUTHORS   Ko,M.S., Threat,T.A., Wang,X., Horton,J.H., Cui,Y., Wang,X.,
            Pryor,E., Paris,J., Wells-Smith,J., Kitchen,J.R., Rowe,L.B.,
            Eppig,J., Satoh,T., Brant,L., Fujiwara,H., Yotsumoto,S. and
            Nakashima,H.
  TITLE     Genome-wide mapping of unselected transcripts from extraembryonic
            tissue of 7.5-day mouse embryos reveals enrichment in the t-complex
            and under-representation on the X chromosome
  JOURNAL   Hum Mol Genet 7 (12), 1967-1978 (1998)
   PUBMED   9811942
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AL772310.27.
            
            On May 2, 2007 this sequence version replaced NM_178603.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK031229.1, AK007405.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-122               AL772310.27        108954-109075       c
            123-2103            AL772310.27        100589-102569       c
FEATURES             Location/Qualifiers
     source          1..2103
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 26.54 cM"
     gene            1..2103
                     /gene="Mrpl50"
                     /gene_synonym="D4Wsu125e"
                     /note="mitochondrial ribosomal protein L50"
                     /db_xref="GeneID:28028"
                     /db_xref="MGI:MGI:107329"
     exon            1..122
                     /gene="Mrpl50"
                     /gene_synonym="D4Wsu125e"
                     /inference="alignment:Splign:2.1.0"
     CDS             31..510
                     /gene="Mrpl50"
                     /gene_synonym="D4Wsu125e"
                     /note="39S ribosomal protein L50, mitochondrial; L50mt;
                     MRP-L50"
                     /codon_start=1
                     /product="large ribosomal subunit protein mL50"
                     /protein_id="NP_848718.1"
                     /db_xref="CCDS:CCDS18174.1"
                     /db_xref="GeneID:28028"
                     /db_xref="MGI:MGI:107329"
                     /translation="MAALIVSRLARRGWLWKLPLATRREFWSRSRKEKEPVVAETVEE
                     VKKEPVLVCPPLRSRAYTPPSDLQSRLESHIKEVLGSSLPNNWQDISLDDGHMKFRLL
                     AGLADGLGHAVPNSRLHQMCRVRDVLDFYNVPVQDKSKFDELVASNLPPNLKISWSY"
     exon            123..2103
                     /gene="Mrpl50"
                     /gene_synonym="D4Wsu125e"
                     /inference="alignment:Splign:2.1.0"
     regulatory      710..715
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl50"
                     /gene_synonym="D4Wsu125e"
                     /note="hexamer: AATAAA"
     polyA_site      734
                     /gene="Mrpl50"
                     /gene_synonym="D4Wsu125e"
                     /note="major polyA site"
ORIGIN      
        1 cgtctggcgc tcttgggttg cttgtcgaga atggcggcgc tgatcgtgtc tcggttagca
       61 agaagaggct ggctgtggaa gcttcccttg gcaacacgta gagaattttg gtctcgatcc
      121 aggaaggaga aggagccagt tgtggcagag acagtggaag aagtgaaaaa agaacctgtt
      181 ttggtgtgtc cacccttacg aagccgagca tacacaccgc ccagtgatct ccagagtcgc
      241 ttggaatctc atattaaaga agttcttggt tcatctcttc ctaataactg gcaagatatc
      301 tccctggatg atggacatat gaagttcaga ctcttagcag gcttagctga tggcttaggc
      361 catgcggtcc ctaactccag gcttcaccaa atgtgcaggg tcagagatgt tcttgatttc
      421 tataatgttc ctgttcaaga caaatctaaa tttgatgaac tcgttgctag taatttacct
      481 cccaatttga aaatcagttg gagttactga gcagtctggt cagagaccac gttgggggtc
      541 attcattctt attctcacta gcgtgactga aaagtaccag aacttttctc aaaacttcaa
      601 ttttgtataa tttttttttt tgctccttgt agaagagcac atctcccctc ccccaaagga
      661 gaatcaacaa agaaaacgtt ttcacatttg ctaaagctat ttttccccca ataaaatcaa
      721 gtcttgataa cttatgaaaa ctttgttatt ccaaggtata tagtcagggt tgttgggagg
      781 aacagaagtg acagcatgca aacatagtta aaggaggttt atgatgttag ctcacattag
      841 gatctgggca cttcatcaat ggctgtgtca cccttcacga ggctgactgt ctcagcagta
      901 ccaagctgtt gctgagagcc tgggggattc tttgaaaagc ctactgacct tcaattcatg
      961 ctggccgcct gaagaagctg gttctaatat ggacgaaaag atgcagcaat ggcaggaaca
     1021 agatggatgt acttgtcagt cgagtgaagg caagcaggtg gaaggaaaat cagaccttcc
     1081 ttctgcatgg gttctgccca catttactgt gcacttccct ctcgagagac aatctgctta
     1141 agaaaatccc ttagtggagc ggccagctgc ttgtctttta gttgactcca gatcagtcag
     1201 tgacaaccaa gattaaccat aacacaaaaa tactaagtac ctcgggcttc agataagagg
     1261 ccattgcaaa gatgttttct ttgcctgtca tacggttaaa gtagtagttt caataaaatg
     1321 ttcttattaa ggctcaaaga tatggggcta ttatatatac aaataagaaa atgtatagtg
     1381 agaattttgg tgtcttaaaa agaaacacag aaatactgta ggtgtggaat ctggggctgc
     1441 ttcagacttg tccacagcag ctgactaatt tgccttgtgc tctagcaggg gcttgattct
     1501 tccagctgca gatggtttct gtgattgtgt gaggttttga attctggggg ttcttcagag
     1561 gataaatgtt agggctctaa gaggcgctga gttgttgatt gtttgctgtt ggttgtgatt
     1621 tgttaagcac tcgtgaacaa agaagaaaca acaagaagaa attagatgtc ctgatgcttg
     1681 ccccaaggaa cttgatgccc ctaatgggca gaaagtctaa tagtaacatt atcccctttc
     1741 ccctctatcc ttttttctgt gctatctagt tttagggggt tgaaggagta gaagaagagg
     1801 agtggagaag ggcggaagaa aaagaaccca caaagtagcc aaaagaccag ctaccaaaca
     1861 aaatgtatta gatgtctgaa ggaaacgtga acatctggtg cacattatag aaagttccac
     1921 tgtgttttac tccataagta aaggtggaag aaagggcaac gtgttctggg ttcatctctt
     1981 gggactaacg gagatttgtt aaagggtaat gactttcttt ctgaatgaaa ttcactttta
     2041 tgtatcactt tattatttct tttaaaatga atattagaaa taaaaacaaa atgtctagca
     2101 gtt
//
