LOCUS       NM_198831               4285 bp    mRNA    linear   ROD 01-AUG-2024
DEFINITION  Mus musculus mitochondrial ribosomal protein L48 (Mrpl48),
            transcript variant 1, mRNA.
ACCESSION   NM_198831 NM_026971 XM_003946242 XM_003946243 XM_003946244
VERSION     NM_198831.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4285)
  AUTHORS   Cheong,A., Lingutla,R. and Mager,J.
  TITLE     Expression analysis of mammalian mitochondrial ribosomal protein
            genes
  JOURNAL   Gene Expr Patterns 38, 119147 (2020)
   PUBMED   32987154
REFERENCE   2  (bases 1 to 4285)
  AUTHORS   Greber,B.J. and Ban,N.
  TITLE     Structure and Function of the Mitochondrial Ribosome
  JOURNAL   Annu Rev Biochem 85, 103-132 (2016)
   PUBMED   27023846
  REMARK    Review article
REFERENCE   3  (bases 1 to 4285)
  AUTHORS   Brown,A., Amunts,A., Bai,X.C., Sugimoto,Y., Edwards,P.C.,
            Murshudov,G., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Structure of the large ribosomal subunit from human mitochondria
  JOURNAL   Science 346 (6210), 718-722 (2014)
   PUBMED   25278503
REFERENCE   4  (bases 1 to 4285)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC117215.3.
            
            On Jan 31, 2018 this sequence version replaced NM_198831.2.
            
            Transcript Variant: This variant (1) represents the protein-coding
            variant.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR6116558.110061.1,
                                           SRR1660819.1001.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-141               AC117215.3         6374-6514
            142-194             AC117215.3         14990-15042
            195-232             AC117215.3         18215-18252
            233-318             AC117215.3         24225-24310
            319-488             AC117215.3         29587-29756
            489-591             AC117215.3         36823-36925
            592-681             AC117215.3         38875-38964
            682-4285            AC117215.3         40122-43725
FEATURES             Location/Qualifiers
     source          1..4285
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 54.36 cM"
     gene            1..4285
                     /gene="Mrpl48"
                     /gene_synonym="1810030E20Rik; 2610028L11Rik; CGI-118;
                     D4Ertd786e; L48mt; MRP-L48"
                     /note="mitochondrial ribosomal protein L48"
                     /db_xref="GeneID:52443"
                     /db_xref="MGI:MGI:1289321"
     exon            1..141
                     /gene="Mrpl48"
                     /gene_synonym="1810030E20Rik; 2610028L11Rik; CGI-118;
                     D4Ertd786e; L48mt; MRP-L48"
                     /inference="alignment:Splign:2.1.0"
     CDS             121..756
                     /gene="Mrpl48"
                     /gene_synonym="1810030E20Rik; 2610028L11Rik; CGI-118;
                     D4Ertd786e; L48mt; MRP-L48"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; 39S ribosomal protein L48, mitochondrial; large
                     ribosomal subunit protein mL48"
                     /codon_start=1
                     /product="large ribosomal subunit protein mL48 isoform 1
                     precursor"
                     /protein_id="NP_942128.2"
                     /db_xref="CCDS:CCDS21502.2"
                     /db_xref="GeneID:52443"
                     /db_xref="MGI:MGI:1289321"
                     /translation="MSGTLGKVLGVWTNTVSKQGFSLLRFRSLGENPIFSAGGILWTS
                     RHYKTKPTRGIGRYRHLVKVQEPKKKKAKVELRAINVGTDYEYGVLNIHLTAYDMSLA
                     ESYAQYVHRLCNRLSIKVEESYAMPTKTMEVMRLPDQGNKMVLDSILTTHERVVQISG
                     LSATFAEIFLEVLQSNLPEGVRLSVREHTEEDFKGRFKARPELEELLAKLN"
     exon            142..194
                     /gene="Mrpl48"
                     /gene_synonym="1810030E20Rik; 2610028L11Rik; CGI-118;
                     D4Ertd786e; L48mt; MRP-L48"
                     /inference="alignment:Splign:2.1.0"
     exon            195..232
                     /gene="Mrpl48"
                     /gene_synonym="1810030E20Rik; 2610028L11Rik; CGI-118;
                     D4Ertd786e; L48mt; MRP-L48"
                     /inference="alignment:Splign:2.1.0"
     exon            233..318
                     /gene="Mrpl48"
                     /gene_synonym="1810030E20Rik; 2610028L11Rik; CGI-118;
                     D4Ertd786e; L48mt; MRP-L48"
                     /inference="alignment:Splign:2.1.0"
     exon            319..488
                     /gene="Mrpl48"
                     /gene_synonym="1810030E20Rik; 2610028L11Rik; CGI-118;
                     D4Ertd786e; L48mt; MRP-L48"
                     /inference="alignment:Splign:2.1.0"
     exon            489..591
                     /gene="Mrpl48"
                     /gene_synonym="1810030E20Rik; 2610028L11Rik; CGI-118;
                     D4Ertd786e; L48mt; MRP-L48"
                     /inference="alignment:Splign:2.1.0"
     exon            592..681
                     /gene="Mrpl48"
                     /gene_synonym="1810030E20Rik; 2610028L11Rik; CGI-118;
                     D4Ertd786e; L48mt; MRP-L48"
                     /inference="alignment:Splign:2.1.0"
     exon            682..4285
                     /gene="Mrpl48"
                     /gene_synonym="1810030E20Rik; 2610028L11Rik; CGI-118;
                     D4Ertd786e; L48mt; MRP-L48"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1347..1352
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl48"
                     /gene_synonym="1810030E20Rik; 2610028L11Rik; CGI-118;
                     D4Ertd786e; L48mt; MRP-L48"
                     /note="hexamer: AACAAA"
     polyA_site      1358
                     /gene="Mrpl48"
                     /gene_synonym="1810030E20Rik; 2610028L11Rik; CGI-118;
                     D4Ertd786e; L48mt; MRP-L48"
                     /note="major polyA site"
     regulatory      2400..2405
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl48"
                     /gene_synonym="1810030E20Rik; 2610028L11Rik; CGI-118;
                     D4Ertd786e; L48mt; MRP-L48"
                     /note="hexamer: AATAAA"
     polyA_site      2424
                     /gene="Mrpl48"
                     /gene_synonym="1810030E20Rik; 2610028L11Rik; CGI-118;
                     D4Ertd786e; L48mt; MRP-L48"
     regulatory      3996..4001
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl48"
                     /gene_synonym="1810030E20Rik; 2610028L11Rik; CGI-118;
                     D4Ertd786e; L48mt; MRP-L48"
                     /note="hexamer: AATAAA"
     polyA_site      4023
                     /gene="Mrpl48"
                     /gene_synonym="1810030E20Rik; 2610028L11Rik; CGI-118;
                     D4Ertd786e; L48mt; MRP-L48"
ORIGIN      
        1 gtctcggtag gatttggtgg acggacgtga tgaagacctt tccggccctg tttccagacg
       61 cctggggtcg tgattgctag ggtggatctt cggtttgctc agaagccgct gtggtcgaga
      121 atgagcggaa ccctgggaaa ggtgctgggt gtgtggacca atactgtttc taagcaaggc
      181 ttttccctcc taaggttcag aagtttggga gagaatccca ttttttctgc aggtggtatt
      241 ctgtggacca gtcggcacta caagacaaag cccactcgtg gcatcggaag atacagacac
      301 ttggtgaaag tgcaggagcc caaaaagaag aaagcaaaag tagaactgag agccattaat
      361 gtggggacag attatgaata tggggtttta aacatccacc tgacagcata tgacatgagt
      421 ctggcagaaa gttatgccca gtatgtccac cgcctctgca accggctgtc catcaaagtc
      481 gaggaaagct atgcgatgcc taccaaaacc atggaagtga tgcgactgcc agaccaaggc
      541 aacaaaatgg tcctagactc catccttacc acccatgagc gagtggtgca gatcagcggt
      601 ctgagtgcta catttgcaga gattttcttg gaagtactcc aaagcaatct tccagaagga
      661 gtcagattgt ccgtgaggga gcacactgaa gaagacttca agggaaggtt caaagctcgg
      721 ccggaactgg aagagttgtt ggccaagttg aactaaaaat actgcaagcc cttcatgtga
      781 ttgttggtct ccgagaagct gctcctgcaa gatcagggtt aaggaggagc gtgaatgctc
      841 gtgctgggaa tgcctccttg catctgtgcc ccgggcttgc cagttaccac ttcccataac
      901 aaaacctagg accttctcca cctaataaat gtctgctgtt gccagtgtgt gtgtgtttgt
      961 gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtggct ttggctgtgt gtgtttatca
     1021 gttatcttgt gaggtatctt taaggaattc tgtttctctt tgtctgaaca tgttctcatc
     1081 ctaccatact gttttagagt gaattcattc tctaaaacag tctgatgtaa actgattgtt
     1141 tgtttgagac actgtctatc tgtagccttg gaacttacta tatagatggg ggtagtctca
     1201 aactcacaga gatccacctg cctcctttcc cccaatttcc accctccaaa tgctggggtt
     1261 aaaggttgta tgccattgtg cccaatatga actcatctct taaagtaata ctacagcatg
     1321 gaggtttatg attaagtaga gattgcaaca aaagcaaact ctgtattggt ctattttttg
     1381 ttgctataat gaagttcctg catctgggtt ctttataaag aaaaagggtt tgaccaattg
     1441 taatagtaca tacctgtacg ttcagcactt aggaggtgga ggattagagt tcagggtcat
     1501 ccacaggtac agagtgagtt ccaggacaac ttgggtcaca tgacatacat acatacatat
     1561 atacatacat gcatacatac atacataaaa gatgcttgct aaatgtgatt gcatgtatca
     1621 ccccagcatc caggagcttg aagcaggagg attgcaagtt taaaatattg aggggaagga
     1681 aatctaacag caagctcttg caagctgtga gtgaatcacc agctgccaac tcccctcaaa
     1741 agtcataatc ccaccataca gaccagaaaa caagttgtgt gaagttacag tagcttacca
     1801 aggagaacaa ctcacaagtt ttcttccgta gaaggctgga tacaacatgg gctgtctgct
     1861 tccccttata aaggttgtcc taaggaggaa ggggcagatg tttcaagctg gagctagatg
     1921 tgtgctccat tgggtttcat tatatgtgac cctaagagag tctgtttctc ctcagccctc
     1981 gctgcagaac ccagtgaagc ttgtgactgt agcctcgaag atctattggt cagactatct
     2041 cccacccctc ttaccaggta aacaaatgtt aagagccatt tccatttctc agagcagagt
     2101 aacagaagcc ttttgattct aagaggagga tacatcatga actaggtcag tgccacaagt
     2161 tctccaaagt gacagaatcc agtcgcttcc tgcttacgag ataagcctga ctcacccctc
     2221 agccgtgatg ggaaggaagc ctcagactgg gaaacaggac cgaatcctgc tgccactctg
     2281 ccaagagatg tcctgtgacc ttgggcaaag catgctctct agagccttag cttctcttta
     2341 ctcagagtcc tgtgggctgg ctaactagtt cctaagtatt tcagctgcag tgtgttgtca
     2401 ataaaatccc aagtcctgct cccacatact ggtaaatagc aagtctgggt aaccagaaga
     2461 ctctgccagg ttctgaaatg gagcgcatgt gacactgccc gtgtgcattg ggagcagagc
     2521 agtgcatata tgtgtgtgtg tgtgtgtgtg tgtacacatg tgcatacagt tatttacctg
     2581 tgaatcttca cattgttata taccctgaac tttgctctca ttggccagat actgttattt
     2641 tattttcctg atagaaattc agcaataagc agttctaatc cagaacatca ctctgcactt
     2701 gagaaattct gcctaaaaga gttcacatgg gaaatcctga cctgctgagc atggtacttg
     2761 aattcagttg ttacccccac ccccacccct caccaaacta ctagccttag tggtgttttt
     2821 agttttttgg ttttgttctg tttcgaggta agagtcttaa catgtagcct tggctggcct
     2881 ggactggcaa aatgcttctg tgtttgcaga cacatacttg ccccaagaga ctggtaaggg
     2941 aataagagct actgtgtacc ttgcacaagg tctagctcag taagcagcta ttctacatga
     3001 agacacagat gctcagaagc aagcacacca gagtcacctg gattatattc tcagagaagc
     3061 aacccagcag caacatctga gaaatgataa gattcaaaga tgtggattct gaaacggtgt
     3121 attttagtca cagagaaaag gagtgaacca ctttggcctt ttgggaactg cagcagtact
     3181 gagcctctgg tcttccattt ctaggactag tggatttagg gaaggagtga tgttccagta
     3241 tgtattggca tgagctagac ctgatagatg ctgtaggcag aagtggacaa ggacttgtgc
     3301 ttgttttttc tgtgcttaca tttctctgtg ctgtttttaa tccagatgcc tatatcacct
     3361 ggctgctgca cctccctgta ataactcatt ctcagacctt tttgctcact tctgggacat
     3421 tcctttgcag atagtaccca gattaaaaaa gaatgaattc tttagaataa tagttgctaa
     3481 gcaggagaag atggttccct acttccctgc agccttaatg cctggctgga gcagaggagg
     3541 gagccctggc tttctctgca gaggagatgt atacaatttc agtttggatt cactccagtt
     3601 ctctttgggt ttctaaagtc agcagctcaa ggatgcagtc tggccacttc actgcgggtg
     3661 ggcaggaggg aagaggacct tactcatcta gcaaaatgca ctacagtgcg tctttatacc
     3721 aagcacaagg ccaagtcccc aggcaaggac cttgcaggga ggaactaaca catgagtctt
     3781 ccctaagcct cttgaagagg gccacccggc taagaagtcc tgtaatcaga gtattaggga
     3841 aaagttcccc aactctaaca actccagcag gctagccttg acaacccatc ccaatgagac
     3901 aattagacta acggccgtga aaaggtaggg gtgatttagt acagtggaaa gaggagcctg
     3961 tttgacttta tggactgaca tggactttag gtttaaataa aagcattggg gcataattaa
     4021 gtagatctgt tcacagtctg gtctccttga tctttgtctc agctctagtt ctgtaaagtg
     4081 gcttgaaaaa atcttggggc tagagaggtg gttcagtagt taaaggcgct tgttgctttt
     4141 gcagaggacc tggctttagt tccctgcacc cacattgtgc ctcaaacaaa agcaacgcca
     4201 gttccagggg atctgatgct ctcttctggc cttggtaggc accaggccca cacaaacaca
     4261 tacatgcagg caaaactctt atgca
//
