LOCUS       NM_025927               2431 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus mitochondrial ribosomal protein L45 (Mrpl45), mRNA.
ACCESSION   NM_025927
VERSION     NM_025927.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2431)
  AUTHORS   Cheong,A., Lingutla,R. and Mager,J.
  TITLE     Expression analysis of mammalian mitochondrial ribosomal protein
            genes
  JOURNAL   Gene Expr Patterns 38, 119147 (2020)
   PUBMED   32987154
REFERENCE   2  (bases 1 to 2431)
  AUTHORS   Greber,B.J. and Ban,N.
  TITLE     Structure and Function of the Mitochondrial Ribosome
  JOURNAL   Annu Rev Biochem 85, 103-132 (2016)
   PUBMED   27023846
  REMARK    Review article
REFERENCE   3  (bases 1 to 2431)
  AUTHORS   Brown,A., Amunts,A., Bai,X.C., Sugimoto,Y., Edwards,P.C.,
            Murshudov,G., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Structure of the large ribosomal subunit from human mitochondria
  JOURNAL   Science 346 (6210), 718-722 (2014)
   PUBMED   25278503
REFERENCE   4  (bases 1 to 2431)
  AUTHORS   Diehl,F., Brown,M.A., van Amerongen,M.J., Novoyatleva,T.,
            Wietelmann,A., Harriss,J., Ferrazzi,F., Bottger,T., Harvey,R.P.,
            Tucker,P.W. and Engel,F.B.
  TITLE     Cardiac deletion of Smyd2 is dispensable for mouse heart
            development
  JOURNAL   PLoS One 5 (3), e9748 (2010)
   PUBMED   20305823
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY263659.1, AK011163.1 and AL596088.14.
            
            On Dec 17, 2009 this sequence version replaced NM_025927.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK081922.1, AK011163.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-224               BY263659.1         1-224
            225-1617            AK011163.1         94-1486
            1618-2431           AL596088.14        2023-2836
FEATURES             Location/Qualifiers
     source          1..2431
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 60.95 cM"
     gene            1..2431
                     /gene="Mrpl45"
                     /gene_synonym="2600005P05Rik"
                     /note="mitochondrial ribosomal protein L45"
                     /db_xref="GeneID:67036"
                     /db_xref="MGI:MGI:1914286"
     exon            1..224
                     /gene="Mrpl45"
                     /gene_synonym="2600005P05Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             159..1079
                     /gene="Mrpl45"
                     /gene_synonym="2600005P05Rik"
                     /note="39S ribosomal protein L45, mitochondrial; L45mt;
                     MRP-L45"
                     /codon_start=1
                     /product="large ribosomal subunit protein mL45"
                     /protein_id="NP_080203.1"
                     /db_xref="CCDS:CCDS25318.1"
                     /db_xref="GeneID:67036"
                     /db_xref="MGI:MGI:1914286"
                     /translation="MAAPVPRGLSSLYRTLGWWSRQPILVTQSTTVVQVKTKSRFRPP
                     TPEPKYKTEKEFLEYARKAGLVIPQERLERPIHLACTAGIFDPYVPPEGDARMSSLSK
                     EGLTQRTERLRKNAASQLAIRKIREFDANFKTKDFPEKAKDIFIEAHLCLNNSDHDRL
                     HTLVTEHCFPDMVWDLKYKTVRWGFVESLEPAQVVHVRCSGLVNQSNMYGQVTVRLHT
                     RQTLAIYDRFGRLMYGQEDVPKDVLEYVVFERHLMNPYGSWRMHAKIVPAWAPPKQPI
                     LKTLMIPGPQLKPWEEYEETQGEAQKPQLA"
     exon            225..402
                     /gene="Mrpl45"
                     /gene_synonym="2600005P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            403..520
                     /gene="Mrpl45"
                     /gene_synonym="2600005P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            521..619
                     /gene="Mrpl45"
                     /gene_synonym="2600005P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            620..668
                     /gene="Mrpl45"
                     /gene_synonym="2600005P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            669..818
                     /gene="Mrpl45"
                     /gene_synonym="2600005P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            819..992
                     /gene="Mrpl45"
                     /gene_synonym="2600005P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            993..2431
                     /gene="Mrpl45"
                     /gene_synonym="2600005P05Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1594..1599
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl45"
                     /gene_synonym="2600005P05Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1618
                     /gene="Mrpl45"
                     /gene_synonym="2600005P05Rik"
                     /note="major polyA site"
ORIGIN      
        1 tcccctggag agcgtgcgcg tgcgcgcgac tcacctttcg gcctggggcg cgcgccctgg
       61 aaaattccac tccccagctc gctccgccct ctgcgccttt tctccggctc ggtgatctgc
      121 ggctaggcta gcatcccggc ggcctttgcg cgagcaaaat ggcggccccc gtacctcggg
      181 gcttgtcctc cttatacagg actttgggat ggtggtctcg gcagcccatt ctggtgactc
      241 agtccacaac tgtagttcaa gttaaaacca aaagccgttt tagaccccca actcctgaac
      301 ccaagtacaa aacagagaag gagtttttgg agtatgccag gaaagcggga ttggtcattc
      361 cacaggaacg gttggagcgc cctatacatt tggcctgtac agctggtata tttgatccct
      421 atgttccacc agagggtgat gctcgaatgt catctctttc aaaggaagga ttgacgcaga
      481 gaactgagcg attgagaaag aatgcggcat cacagctggc aatccgaaag ataagagaat
      541 ttgatgcaaa ttttaaaaca aaagacttcc ctgaaaaagc taaggatatt ttcattgaag
      601 ctcacctttg tctaaacaac tcagaccatg accggcttca taccttggta accgaacact
      661 gttttccgga catggtctgg gacctcaagt acaagactgt acgctggggc tttgtggaat
      721 ctctagagcc agcccaagtg gttcatgtcc gttgctcagg cctggtgaac cagagcaaca
      781 tgtatggcca ggtcactgtg cgcctacaca ctcggcagac tttggccatt tatgatcggt
      841 ttggcagatt gatgtatgga caggaagatg tgcccaagga tgtcctggaa tatgtggtgt
      901 ttgaaagaca cttgatgaac ccgtatggga gctggagaat gcatgccaag attgtgcccg
      961 cgtgggcacc ccctaagcag cccatcctca agaccttgat gattcctggt cctcagctga
     1021 aaccctggga ggagtacgaa gagactcaag gggaggccca gaagcctcag ctagcctgat
     1081 ggcgttaatg actcctgagg agcctagcag ttgtggtgaa catctttaat cccagcactc
     1141 agaaggcaga ggcaggtgga tttctgtgag ttcaaggcca gtctggtcta cagagcaagt
     1201 tgcaggacaa ccagagctac acagagaaac cctgtctcag gaaaaaaaaa caaaaagaaa
     1261 aaagacaaaa agactcctga ggtgttccga tggggctgca aagtcacctg tacccacctg
     1321 taccccgaag gcttcccgtg ctgtctcctg tcctgcctgg gtcagcagtc ccccaagccc
     1381 ctcacagtca tggctgattg tgtggccagg tggtggctgg ggtgccccgc cttggagcat
     1441 cttctgttta cagccatgtt cagcttctga ggtgaaatga gaagcagcag cagagagaac
     1501 aaacgcgaca ctgggctttt cccagcagca gcaagctgtg gcatcagacc cacagctttc
     1561 ttttttctaa ttataggccg agtcagcatt tggaataaaa tactgtcaaa gagttggata
     1621 aactgtgtgt tctgtacatt ttccctggtt cagactggga cggagcggtt ctgtgatgtc
     1681 aggcatggga aagcagtata gttataagtg atgcggcttc caggaactct agatgggaag
     1741 accttagagt gtctacaaac tagggcaccc tgctacagtc ctgccacgtg ggaagttggg
     1801 gcaagaagag gaccaggaac tagatgccat ccttggcaac acacagttta aaagtcactt
     1861 aatcttatat gcctgagtgt tctgtctgca cctgtgttta tgtactacac gcatggctgg
     1921 tgcccttgga ggtccaaaga gggtgtcaga tcccctggaa ctagagttac ggatggttgt
     1981 gaaccaccac aggtgctagg aactggatct gtgtcttctg caagagcaac aggtattctt
     2041 tttttttttt ttgagatgta tttattttat gtgtgtgagt gcaccgtcac tgtcttcaga
     2101 cacaccagaa gaggatccca ttacagatgg ttgtgagcca ccatgtggtt cctgggactt
     2161 gaactcggga cctttggaag agcagtcagt gttcttaccc actgagccat ctccaacctg
     2221 taacaagtat tcttagctac tgagccatct ttccatccca gaatactact ttaaaagatc
     2281 tctttaatat agatgtttta attttttttt cttcaggttt ctctgtgtaa catccctgta
     2341 acttgctttg tataccaggc tagcctccct tatagagatc tgcctcccat cctccctccc
     2401 cctttgcctg agattaaagg agtgctacac c
//
