LOCUS       NM_001359476             689 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus mitochondrial ribosomal protein L42 (Mrpl42),
            transcript variant 2, mRNA.
ACCESSION   NM_001359476 XM_006513979
VERSION     NM_001359476.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 689)
  AUTHORS   Wang,Y., Yasmin,L., Li,L., Gao,P., Xu,X., Sun,X. and Godbout,R.
  TITLE     DDX1 vesicles control calcium-dependent mitochondrial activity in
            mouse embryos
  JOURNAL   Nat Commun 13 (1), 3794 (2022)
   PUBMED   35778392
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 689)
  AUTHORS   Chern,T., Achilleos,A., Tong,X., Hill,M.C., Saltzman,A.B.,
            Reineke,L.C., Chaudhury,A., Dasgupta,S.K., Redhead,Y., Watkins,D.,
            Neilson,J.R., Thiagarajan,P., Green,J.B.A., Malovannaya,A.,
            Martin,J.F., Rosenblatt,D.S. and Poche,R.A.
  TITLE     Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin
            metabolism and ribosomopathy
  JOURNAL   Nat Commun 13 (1), 134 (2022)
   PUBMED   35013307
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 689)
  AUTHORS   Cheong,A., Lingutla,R. and Mager,J.
  TITLE     Expression analysis of mammalian mitochondrial ribosomal protein
            genes
  JOURNAL   Gene Expr Patterns 38, 119147 (2020)
   PUBMED   32987154
REFERENCE   4  (bases 1 to 689)
  AUTHORS   Greber,B.J. and Ban,N.
  TITLE     Structure and Function of the Mitochondrial Ribosome
  JOURNAL   Annu Rev Biochem 85, 103-132 (2016)
   PUBMED   27023846
  REMARK    Review article
REFERENCE   5  (bases 1 to 689)
  AUTHORS   Brown,A., Amunts,A., Bai,X.C., Sugimoto,Y., Edwards,P.C.,
            Murshudov,G., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Structure of the large ribosomal subunit from human mitochondria
  JOURNAL   Science 346 (6210), 718-722 (2014)
   PUBMED   25278503
REFERENCE   6  (bases 1 to 689)
  AUTHORS   Nelson,P.S., Pritchard,C., Abbott,D. and Clegg,N.
  TITLE     The human (PEDB) and mouse (mPEDB) Prostate Expression Databases
  JOURNAL   Nucleic Acids Res 30 (1), 218-220 (2002)
   PUBMED   11752298
REFERENCE   7  (bases 1 to 689)
  AUTHORS   Schriml,L.M., Peterson,R.J., Gerrard,B. and Dean,M.
  TITLE     Use of denaturing HPLC to map human and murine genes and to
            validate single-nucleotide polymorphisms
  JOURNAL   Biotechniques 28 (4), 740-745 (2000)
   PUBMED   10769753
REFERENCE   8  (bases 1 to 689)
  AUTHORS   Goldschmidt-Reisin,S., Kitakawa,M., Herfurth,E.,
            Wittmann-Liebold,B., Grohmann,L. and Graack,H.R.
  TITLE     Mammalian mitochondrial ribosomal proteins. N-terminal amino acid
            sequencing, characterization, and identification of corresponding
            gene sequences
  JOURNAL   J Biol Chem 273 (52), 34828-34836 (1998)
   PUBMED   9857009
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DV060222.1, DV050100.1, AK002530.1 and AI839395.1.
            
            On Jan 13, 2018 this sequence version replaced XM_006513979.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC024337.1, CA464746.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164143 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-18                DV060222.1         55-72
            19-19               DV050100.1         19-19
            20-22               DV060222.1         74-76
            23-672              AK002530.1         2-651
            673-689             AI839395.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..689
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 49.39 cM"
     gene            1..689
                     /gene="Mrpl42"
                     /gene_synonym="2700009F22Rik; 2900055D03Rik; D10Ertd322e;
                     HSPC204; L31mt; L42mt; MRP-L31; MRP-L42; MRP-S32; PTD007;
                     Rpml31; S32mt"
                     /note="mitochondrial ribosomal protein L42"
                     /db_xref="GeneID:67270"
                     /db_xref="MGI:MGI:1333774"
     exon            1..44
                     /gene="Mrpl42"
                     /gene_synonym="2700009F22Rik; 2900055D03Rik; D10Ertd322e;
                     HSPC204; L31mt; L42mt; MRP-L31; MRP-L42; MRP-S32; PTD007;
                     Rpml31; S32mt"
                     /inference="alignment:Splign:2.1.0"
     exon            45..184
                     /gene="Mrpl42"
                     /gene_synonym="2700009F22Rik; 2900055D03Rik; D10Ertd322e;
                     HSPC204; L31mt; L42mt; MRP-L31; MRP-L42; MRP-S32; PTD007;
                     Rpml31; S32mt"
                     /inference="alignment:Splign:2.1.0"
     CDS             118..546
                     /gene="Mrpl42"
                     /gene_synonym="2700009F22Rik; 2900055D03Rik; D10Ertd322e;
                     HSPC204; L31mt; L42mt; MRP-L31; MRP-L42; MRP-S32; PTD007;
                     Rpml31; S32mt"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 2; mitochndrial ribosomal protein L42; 28S
                     ribosomal protein L42, mitochondrial; 39S ribosomal
                     protein L42, mitochondrial; 28S ribosomal protein S32,
                     mitochondrial; 39S ribosomal protein L31, mitochondrial;
                     large ribosomal subunit protein mL42"
                     /codon_start=1
                     /product="large ribosomal subunit protein mL42 isoform 1
                     precursor"
                     /protein_id="NP_001346405.1"
                     /db_xref="CCDS:CCDS24137.1"
                     /db_xref="GeneID:67270"
                     /db_xref="MGI:MGI:1333774"
                     /translation="MAAAVKWAISNRTIWKHLLPIQNGALSSACHKSTYSSLPDDYNC
                     QVDLALTADGRTIVCYHPSVDIPYEHTKPIPQPDLLHNNEETHEQILKAKLEVRKSKQ
                     LEQGPMIEQLSKVFYTTKHRWYPHGQYHNRRKKLNPPRDR"
     exon            185..248
                     /gene="Mrpl42"
                     /gene_synonym="2700009F22Rik; 2900055D03Rik; D10Ertd322e;
                     HSPC204; L31mt; L42mt; MRP-L31; MRP-L42; MRP-S32; PTD007;
                     Rpml31; S32mt"
                     /inference="alignment:Splign:2.1.0"
     exon            249..333
                     /gene="Mrpl42"
                     /gene_synonym="2700009F22Rik; 2900055D03Rik; D10Ertd322e;
                     HSPC204; L31mt; L42mt; MRP-L31; MRP-L42; MRP-S32; PTD007;
                     Rpml31; S32mt"
                     /inference="alignment:Splign:2.1.0"
     exon            334..500
                     /gene="Mrpl42"
                     /gene_synonym="2700009F22Rik; 2900055D03Rik; D10Ertd322e;
                     HSPC204; L31mt; L42mt; MRP-L31; MRP-L42; MRP-S32; PTD007;
                     Rpml31; S32mt"
                     /inference="alignment:Splign:2.1.0"
     exon            501..673
                     /gene="Mrpl42"
                     /gene_synonym="2700009F22Rik; 2900055D03Rik; D10Ertd322e;
                     HSPC204; L31mt; L42mt; MRP-L31; MRP-L42; MRP-S32; PTD007;
                     Rpml31; S32mt"
                     /inference="alignment:Splign:2.1.0"
     regulatory      652..657
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl42"
                     /gene_synonym="2700009F22Rik; 2900055D03Rik; D10Ertd322e;
                     HSPC204; L31mt; L42mt; MRP-L31; MRP-L42; MRP-S32; PTD007;
                     Rpml31; S32mt"
                     /note="hexamer: AATAAA"
     polyA_site      673
                     /gene="Mrpl42"
                     /gene_synonym="2700009F22Rik; 2900055D03Rik; D10Ertd322e;
                     HSPC204; L31mt; L42mt; MRP-L31; MRP-L42; MRP-S32; PTD007;
                     Rpml31; S32mt"
                     /note="major polyA site"
ORIGIN      
        1 cggcgccttt aggacccaga ttgaagcaag atggcgagcg cgcggaacga aaatctgtgt
       61 gcctagcaac agctttcact tcacaatatc gttttttcaa atcacttgct aaggatcatg
      121 gctgcggcag taaaatgggc gatatcaaac agaactatct ggaagcattt acttccaatc
      181 caaaacggag ctttgtctag tgcttgtcac aaatccacat actcttctct tccggatgac
      241 tacaattgcc aggtggacct cgccttgaca gccgacggca ggacaatagt gtgctaccac
      301 ccttctgtgg acatccccta cgaacacacc aaacccatcc ctcaaccaga tcttctgcat
      361 aataatgagg aaacccacga gcagatcctg aaagccaagt tagaagttag aaagagcaag
      421 cagctggagc aagggcccat gatagaacaa ctgagcaagg tgttctacac cacgaagcat
      481 cgctggtacc cgcacggaca gtatcacaat cgtcgtaaga aactgaatcc tcccagagac
      541 agatgacgac tcatgattcc ccggacatcg ggaaattttg ctttgtgtct tatttgccag
      601 ctgagaaaat gtacatggta ccatcattaa ggtggtcggt atataggaaa aaataaaaat
      661 accctttcat gtaaaaaaaa aaaaaaaaa
//
