LOCUS       NM_001031808            2423 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus mitochondrial ribosomal protein L41 (Mrpl41), mRNA.
ACCESSION   NM_001031808 XM_885135 XM_896011 XM_912794 XM_922501
VERSION     NM_001031808.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2423)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2423)
  AUTHORS   Cheong,A., Lingutla,R. and Mager,J.
  TITLE     Expression analysis of mammalian mitochondrial ribosomal protein
            genes
  JOURNAL   Gene Expr Patterns 38, 119147 (2020)
   PUBMED   32987154
REFERENCE   3  (bases 1 to 2423)
  AUTHORS   Greber,B.J. and Ban,N.
  TITLE     Structure and Function of the Mitochondrial Ribosome
  JOURNAL   Annu Rev Biochem 85, 103-132 (2016)
   PUBMED   27023846
  REMARK    Review article
REFERENCE   4  (bases 1 to 2423)
  AUTHORS   Brown,A., Amunts,A., Bai,X.C., Sugimoto,Y., Edwards,P.C.,
            Murshudov,G., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Structure of the large ribosomal subunit from human mitochondria
  JOURNAL   Science 346 (6210), 718-722 (2014)
   PUBMED   25278503
REFERENCE   5  (bases 1 to 2423)
  AUTHORS   Goldschmidt-Reisin,S., Kitakawa,M., Herfurth,E.,
            Wittmann-Liebold,B., Grohmann,L. and Graack,H.R.
  TITLE     Mammalian mitochondrial ribosomal proteins. N-terminal amino acid
            sequencing, characterization, and identification of corresponding
            gene sequences
  JOURNAL   J Biol Chem 273 (52), 34828-34836 (1998)
   PUBMED   9857009
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK032370.1, AK003340.1, AK011837.1 and AL732585.8.
            
            On Aug 30, 2006 this sequence version replaced NM_001031808.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK032370.1, AK011837.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-260               AK032370.1         1-260
            261-773             AK003340.1         176-688
            774-1281            AK032370.1         774-1281
            1282-1389           AK011837.1         1220-1327
            1390-2011           AK032370.1         1390-2011
            2012-2423           AL732585.8         14993-15404         c
FEATURES             Location/Qualifiers
     source          1..2423
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 16.88 cM"
     gene            1..2423
                     /gene="Mrpl41"
                     /gene_synonym="MRP-L27; Rpml27"
                     /note="mitochondrial ribosomal protein L41"
                     /db_xref="GeneID:107733"
                     /db_xref="MGI:MGI:1333816"
     exon            1..211
                     /gene="Mrpl41"
                     /gene_synonym="MRP-L27; Rpml27"
                     /inference="alignment:Splign:2.1.0"
     exon            212..2423
                     /gene="Mrpl41"
                     /gene_synonym="MRP-L27; Rpml27"
                     /inference="alignment:Splign:2.1.0"
     CDS             235..642
                     /gene="Mrpl41"
                     /gene_synonym="MRP-L27; Rpml27"
                     /note="39S ribosomal protein L41, mitochondrial; L41mt;
                     MRP-L41; large ribosomal subunit protein mL41"
                     /codon_start=1
                     /product="large ribosomal subunit protein mL41 precursor"
                     /protein_id="NP_001026978.2"
                     /db_xref="CCDS:CCDS15744.1"
                     /db_xref="GeneID:107733"
                     /db_xref="MGI:MGI:1333816"
                     /translation="MGFLTAVTQGLVRGADRMSKWTSKRGPRTFTKSRGAKKTGIYTS
                     DRKFVQIKEMVPEFVVPDLTGFKLKPYVNYRAPAGIDTPLTAKALFQETVAPAIEKDF
                     KEGTFDANNLEKYGFEPTQEGKLFQLYPKNFPR"
     regulatory      751..756
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl41"
                     /gene_synonym="MRP-L27; Rpml27"
                     /note="hexamer: ATTAAA"
     polyA_site      774
                     /gene="Mrpl41"
                     /gene_synonym="MRP-L27; Rpml27"
                     /note="major polyA site"
     polyA_site      1803
                     /gene="Mrpl41"
                     /gene_synonym="MRP-L27; Rpml27"
ORIGIN      
        1 tggtgaccag tcggcgaggc tcttgctacg gagtgtctga ccccgcctac ggtcggaaac
       61 gcagggagga ccttgctgtg ccttggaagg agtgaccggt caggcggtgt tttaaacggc
      121 tcaggctggg gaaaccgtgt ctgagctgtc tcaggtcgaa agggttctcc ctttctccct
      181 tgcgggccga gctctagagc cgtcagccca gagctgattt atccagagcc cagcatgggt
      241 ttcctgactg ccgtgactca aggcctggtg cggggagctg acaggatgag caagtggaca
      301 agcaagcggg gaccacgcac cttcactaag agtcggggtg ccaagaaaac aggcatctat
      361 acttctgata ggaagtttgt gcaaataaaa gaaatggttc cagaatttgt cgtcccggac
      421 ttgacgggct tcaagctcaa gccctacgtt aattaccgag ctcctgcagg catagacaca
      481 cctctgaccg ccaaagcgct cttccaggaa acagttgcac ccgctatcga aaaagacttt
      541 aaagaaggga catttgatgc taacaacctg gagaaatacg gcttcgagcc cacacaggaa
      601 ggcaagctgt tccaattata tcctaagaat ttcccacgct agaagaccat gagagaggcc
      661 aaaagtttgt ctacaaagtg gagacagtac tgaccaagcc ttggattctt attgtctcaa
      721 agagtagggg cagcttccta gcgcacttct attaaatgcc tttagtgtct cgtacagtat
      781 gtgttttgaa tcaagtcatt gaagtgtgct gcagggcaga ctccatgcag tagctataga
      841 gttcataaca aatcccaacc aagtcaagtc tgggggcaca cttctctggc tccaaggtga
      901 gggtagttcc tgttgggtga aagtagccat ccccaaggag agccctaaga tggaagtcac
      961 aagagcagtt agtgtcacct gctttcatga ccagtctagt ctacctgatt catcatagcc
     1021 cctgagacat tatttgtccc atttaagact tagctaaccc ttatatttaa caccttttat
     1081 ttataattgg gccagcagtt gagaagtgat ccctttaatg gtaaccaaaa aaaacattgc
     1141 tcaccatgta ttcatgaaga cccaagttaa gcccatactt ataatctcag caataggaag
     1201 gagacaacag gatctctggg gcttgctgcc cagccaagtc tagactagtc agctaacctc
     1261 aaatcccagc aagagaccgt ggctcaagac aggctatcgt gaatggcagc tgaggttaac
     1321 ccctatctgc cacactcatg tatacataga agcaaacaag gtagtattgg acacttagga
     1381 gactaagaag gggttacaag tcagtccagc ctgggctatg tagtaaggtc ttttttattg
     1441 gagacaagag tcttgatgtc ctagaacttg ctatgtagat caccaggccg ccctcagcct
     1501 gacagagatc cgtcttcatg tgcttcctga gtgctgggat taaagggatc aatcaccaca
     1561 gcccgtctta aagagctgtg agctcagcat ttgggaagct taggtaggtg gatcttaagt
     1621 tcaaagccca accagcttag actacatagt aagcttatga tcagcctgaa atatataggc
     1681 ccagggaagc acaagatagc tgggaataca gttcagtgct agaaaaccat aacttgtctg
     1741 ccatgtgtaa gtccctgtat gtgatggaac ttcatttaaa aaaataacat tttctcttct
     1801 gaacacttgt gtatcatact gagggttaga cacattccaa tgctctctcc agataagaca
     1861 atcaaaatgg gactcttgat agctccatag tctgtgttcc catagaagcc atctatgtag
     1921 acataagaac taataagtta ttaatgctat gattaagtga tgagtgatat ggaccataac
     1981 aagtaattca agtttgtgtt cctggatagt gccacttcca gtaccaaaaa aaggtaaaac
     2041 ttctgtttag gaaataactt ctactaattt tataaggtga gagttttaaa agaggggctg
     2101 tagggctagc aagaaggctc agtggtactt cctgcagagc ctgacaccag agttggatcc
     2161 ctgggaccca catgatgaga gatccagctt ctgcatgtcc tgtgatctcc acatgtgcac
     2221 aatattatct gtgtaatcac aaaaaatcaa aactataggg gctgcagacc agaagtgggt
     2281 caggggttac tagtgctctc tgctcttcta gcacttacaa aggtggcaca cagctgtctg
     2341 taactcttac ttccaggtga tccaatatcc tcttctgacc tctgggagca ccaggcacaa
     2401 taaaacactc atgcacaggc tgg
//
