LOCUS       NM_017404               1091 bp    mRNA    linear   ROD 09-JUN-2024
DEFINITION  Mus musculus mitochondrial ribosomal protein L39 (Mrpl39),
            transcript variant 1, mRNA.
ACCESSION   NM_017404 XM_358878
VERSION     NM_017404.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1091)
  AUTHORS   Cheong,A., Lingutla,R. and Mager,J.
  TITLE     Expression analysis of mammalian mitochondrial ribosomal protein
            genes
  JOURNAL   Gene Expr Patterns 38, 119147 (2020)
   PUBMED   32987154
REFERENCE   2  (bases 1 to 1091)
  AUTHORS   Greber,B.J. and Ban,N.
  TITLE     Structure and Function of the Mitochondrial Ribosome
  JOURNAL   Annu Rev Biochem 85, 103-132 (2016)
   PUBMED   27023846
  REMARK    Review article
REFERENCE   3  (bases 1 to 1091)
  AUTHORS   Brown,A., Amunts,A., Bai,X.C., Sugimoto,Y., Edwards,P.C.,
            Murshudov,G., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Structure of the large ribosomal subunit from human mitochondria
  JOURNAL   Science 346 (6210), 718-722 (2014)
   PUBMED   25278503
REFERENCE   4  (bases 1 to 1091)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   5  (bases 1 to 1091)
  AUTHORS   Gitton,Y., Dahmane,N., Baik,S., Ruiz i Altaba,A., Neidhardt,L.,
            Scholze,M., Herrmann,B.G., Kahlem,P., Benkahla,A., Schrinner,S.,
            Yildirimman,R., Herwig,R., Lehrach,H. and Yaspo,M.L.
  CONSRTM   HSA21 expression map initiative
  TITLE     A gene expression map of human chromosome 21 orthologues in the
            mouse
  JOURNAL   Nature 420 (6915), 586-590 (2002)
   PUBMED   12466855
REFERENCE   6  (bases 1 to 1091)
  AUTHORS   Reymond,A., Marigo,V., Yaylaoglu,M.B., Leoni,A., Ucla,C.,
            Scamuffa,N., Caccioppoli,C., Dermitzakis,E.T., Lyle,R., Banfi,S.,
            Eichele,G., Antonarakis,S.E. and Ballabio,A.
  TITLE     Human chromosome 21 gene expression atlas in the mouse
  JOURNAL   Nature 420 (6915), 582-586 (2002)
   PUBMED   12466854
REFERENCE   7  (bases 1 to 1091)
  AUTHORS   O'Brien,T.W., Fiesler,S.E., Denslow,N.D., Thiede,B.,
            Wittmann-Liebold,B., Mougey,E.B., Sylvester,J.E. and Graack,H.R.
  TITLE     Mammalian mitochondrial ribosomal proteins (2). Amino acid
            sequencing, characterization, and identification of corresponding
            gene sequences
  JOURNAL   J Biol Chem 274 (51), 36043-36051 (1999)
   PUBMED   10593885
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT027693.11 and AK007681.1.
            
            On May 28, 2020 this sequence version replaced NM_017404.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC012274.1, AK031942.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164141
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on manual assertion,
                                                  expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-7                 CT027693.11        130998-131004       c
            8-1087              AK007681.1         2-1081
            1088-1091           CT027693.11        114041-114044       c
FEATURES             Location/Qualifiers
     source          1..1091
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 46.92 cM"
     gene            1..1091
                     /gene="Mrpl39"
                     /gene_synonym="C21orf8; MRP-L5; ORF22; Rpml5"
                     /note="mitochondrial ribosomal protein L39"
                     /db_xref="GeneID:27393"
                     /db_xref="MGI:MGI:1351620"
     exon            1..91
                     /gene="Mrpl39"
                     /gene_synonym="C21orf8; MRP-L5; ORF22; Rpml5"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..1038
                     /gene="Mrpl39"
                     /gene_synonym="C21orf8; MRP-L5; ORF22; Rpml5"
                     /note="isoform 1 is encoded by transcript variant 1; 39S
                     ribosomal protein L39, mitochondrial; L39mt; MRP-L39;
                     ribosomal protein, mitochondrial, L5; large ribosomal
                     subunit protein mL39"
                     /codon_start=1
                     /product="large ribosomal subunit protein mL39 isoform 1"
                     /protein_id="NP_059100.3"
                     /db_xref="CCDS:CCDS57035.1"
                     /db_xref="GeneID:27393"
                     /db_xref="MGI:MGI:1351620"
                     /translation="MATAVGRLVLRRPGAGGGARWRFIATSPAAELSPTELTEMRNDL
                     FNREKSRQLSLTPRTEKIEVKHVGKTDPGTVFVMNKNISTPYSCAMHLSEWYCSKSIL
                     ALVDGQPWDMYKPLTKSCEIKFLTFKDPDPKEVNKAYWRSCAMMLGCVIERAFKDDYV
                     VSLVRAPEVPVIAGAFCYDVTLDKRLDEWMPTKENLRSFTKDAHALIYRDLPFETLDV
                     DARVALEIFQHNKYKVDFIEEKASQNPERIVKLHRIGDFIDVSEGPLIPRTSVCFQYE
                     VSAVHNLNPSQPNLIRRFQGLSLPTHLRAQFTIWDKLVERSRKMVTEDEVRQTENTES
                     TQ"
     exon            92..298
                     /gene="Mrpl39"
                     /gene_synonym="C21orf8; MRP-L5; ORF22; Rpml5"
                     /inference="alignment:Splign:2.1.0"
     exon            299..438
                     /gene="Mrpl39"
                     /gene_synonym="C21orf8; MRP-L5; ORF22; Rpml5"
                     /inference="alignment:Splign:2.1.0"
     exon            439..538
                     /gene="Mrpl39"
                     /gene_synonym="C21orf8; MRP-L5; ORF22; Rpml5"
                     /inference="alignment:Splign:2.1.0"
     exon            539..606
                     /gene="Mrpl39"
                     /gene_synonym="C21orf8; MRP-L5; ORF22; Rpml5"
                     /inference="alignment:Splign:2.1.0"
     exon            607..719
                     /gene="Mrpl39"
                     /gene_synonym="C21orf8; MRP-L5; ORF22; Rpml5"
                     /inference="alignment:Splign:2.1.0"
     exon            720..785
                     /gene="Mrpl39"
                     /gene_synonym="C21orf8; MRP-L5; ORF22; Rpml5"
                     /inference="alignment:Splign:2.1.0"
     exon            786..939
                     /gene="Mrpl39"
                     /gene_synonym="C21orf8; MRP-L5; ORF22; Rpml5"
                     /inference="alignment:Splign:2.1.0"
     exon            940..987
                     /gene="Mrpl39"
                     /gene_synonym="C21orf8; MRP-L5; ORF22; Rpml5"
                     /inference="alignment:Splign:2.1.0"
     exon            988..1091
                     /gene="Mrpl39"
                     /gene_synonym="C21orf8; MRP-L5; ORF22; Rpml5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1072..1077
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl39"
                     /gene_synonym="C21orf8; MRP-L5; ORF22; Rpml5"
                     /note="hexamer: AATAAA"
     polyA_site      1091
                     /gene="Mrpl39"
                     /gene_synonym="C21orf8; MRP-L5; ORF22; Rpml5"
                     /note="major polyA site"
ORIGIN      
        1 gagctacctt ggctacttcg ggaagccatg gctaccgcgg tgggaaggct ggttcttcgg
       61 cggcccggcg cgggcggcgg ggctcgctgg agatttatag cgacgtcgcc agctgccgag
      121 ctgtcaccca cggagctgac agaaatgcgg aatgatctgt ttaacagaga gaaaagcagg
      181 cagttatcgt taaccccccg aacggagaag atcgaagtta agcatgttgg gaaaactgat
      241 cccggcactg tcttcgtgat gaataaaaac atctcaaccc cttacagttg tgccatgcat
      301 ctgagtgagt ggtactgcag taagtccatc ctggctcttg tggacggaca accgtgggac
      361 atgtataagc ctctgaccaa gtcttgtgag atcaaatttc ttactttcaa agaccctgac
      421 ccaaaagaag tgaataaggc gtattggcgt tcttgtgcca tgatgctggg ctgtgtaatc
      481 gaaagggcat tcaaagatga ctatgtggtc agcctggtca gagcaccgga agttcctgtg
      541 attgctgggg ccttctgcta tgatgtcact ttggataaga gactggatga gtggatgcca
      601 acaaaagaga acctgcgttc tttcacaaaa gatgcccatg ctttaatata tagggacctt
      661 ccctttgaaa ctctggacgt tgatgcaaga gtggcgctgg aaatatttca acataacaag
      721 tacaaagtgg atttcataga ggagaaggca tctcagaacc ccgagagaat agtcaagtta
      781 cacagaatcg gtgacttcat tgatgtaagt gaaggccccc ttattccgag aacaagtgtt
      841 tgcttccagt atgaagtgtc agcggtccac aatcttaacc ccagccagcc gaacctcatt
      901 cgcagatttc agggcctgtc tttacccacg cacttgagag cacagtttac aatatgggac
      961 aagctagtgg aaagatctcg gaaaatggta actgaagatg aagtcagaca gacagagaac
     1021 accgaatcca cccagtagtg ttctaaaatt taaacttgta gagtaaatta aaataaaagc
     1081 ttttaataca a
//
