LOCUS       NM_053162                663 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus mitochondrial ribosomal protein L34 (Mrpl34), mRNA.
ACCESSION   NM_053162
VERSION     NM_053162.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 663)
  AUTHORS   Cheong,A., Lingutla,R. and Mager,J.
  TITLE     Expression analysis of mammalian mitochondrial ribosomal protein
            genes
  JOURNAL   Gene Expr Patterns 38, 119147 (2020)
   PUBMED   32987154
REFERENCE   2  (bases 1 to 663)
  AUTHORS   Greber,B.J. and Ban,N.
  TITLE     Structure and Function of the Mitochondrial Ribosome
  JOURNAL   Annu Rev Biochem 85, 103-132 (2016)
   PUBMED   27023846
  REMARK    Review article
REFERENCE   3  (bases 1 to 663)
  AUTHORS   Brown,A., Amunts,A., Bai,X.C., Sugimoto,Y., Edwards,P.C.,
            Murshudov,G., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Structure of the large ribosomal subunit from human mitochondria
  JOURNAL   Science 346 (6210), 718-722 (2014)
   PUBMED   25278503
REFERENCE   4  (bases 1 to 663)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   5  (bases 1 to 663)
  AUTHORS   Suzuki,T., Terasaki,M., Takemoto-Hori,C., Hanada,T., Ueda,T.,
            Wada,A. and Watanabe,K.
  TITLE     Structural compensation for the deficit of rRNA with proteins in
            the mammalian mitochondrial ribosome. Systematic analysis of
            protein components of the large ribosomal subunit from mammalian
            mitochondria
  JOURNAL   J Biol Chem 276 (24), 21724-21736 (2001)
   PUBMED   11279069
REFERENCE   6  (bases 1 to 663)
  AUTHORS   Brady,K.P., Rowe,L.B., Her,H., Stevens,T.J., Eppig,J.,
            Sussman,D.J., Sikela,J. and Beier,D.R.
  TITLE     Genetic mapping of 262 loci derived from expressed sequences in a
            murine interspecific cross using single-strand conformational
            polymorphism analysis
  JOURNAL   Genome Res 7 (11), 1085-1093 (1997)
   PUBMED   9371744
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY290822.1, AK018724.1 and BQ174895.1.
            
            On Sep 7, 2006 this sequence version replaced NM_053162.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BQ174895.1, CB954266.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-50                BY290822.1         3-52
            51-642              AK018724.1         3-594
            643-663             BQ174895.1         1-21                c
FEATURES             Location/Qualifiers
     source          1..663
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 34.43 cM"
     gene            1..663
                     /gene="Mrpl34"
                     /gene_synonym="0610007O17Rik; D8Bwg1484e"
                     /note="mitochondrial ribosomal protein L34"
                     /db_xref="GeneID:94065"
                     /db_xref="MGI:MGI:2137227"
     exon            1..142
                     /gene="Mrpl34"
                     /gene_synonym="0610007O17Rik; D8Bwg1484e"
                     /inference="alignment:Splign:2.1.0"
     CDS             78..356
                     /gene="Mrpl34"
                     /gene_synonym="0610007O17Rik; D8Bwg1484e"
                     /note="39S ribosomal protein L34, mitochondrial; L34mt;
                     MRP-L34"
                     /codon_start=1
                     /product="large ribosomal subunit protein bL34m"
                     /protein_id="NP_444392.1"
                     /db_xref="CCDS:CCDS40383.1"
                     /db_xref="GeneID:94065"
                     /db_xref="MGI:MGI:2137227"
                     /translation="MAFLARCFGCQACRSVALLSGRYLQSRVWMGLPDSWPLLSLQQA
                     RGRARGNEYQPSNIKRKHKHGWVRRLSTPAGVQVILRRMLKGRKSLSH"
     exon            143..646
                     /gene="Mrpl34"
                     /gene_synonym="0610007O17Rik; D8Bwg1484e"
                     /inference="alignment:Splign:2.1.0"
     regulatory      618..623
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl34"
                     /gene_synonym="0610007O17Rik; D8Bwg1484e"
                     /note="hexamer: AATAAA"
     polyA_site      640
                     /gene="Mrpl34"
                     /gene_synonym="0610007O17Rik; D8Bwg1484e"
                     /note="major polyA site"
ORIGIN      
        1 gaaggcattg tcaaggagcc cagagtgtag gaactggcat tgacccggac gaccggacca
       61 ttgacccgcc gctggatatg gctttcctag cccggtgctt tgggtgccag gcctgcagat
      121 cggtggccct attgagtggc aggtatctcc agtccagagt ctggatgggg ctcccggact
      181 cctggcctct cctctccctg cagcaggctc gcggccgcgc gcgcggaaac gagtatcagc
      241 cgagcaacat caagcgcaag cacaagcacg gctgggtccg tcggctgagc acgcctgccg
      301 gcgtgcaggt catcctccgt cgcatgctga agggccgcaa gtccctgagc cactgaggag
      361 cgcaacgtcg cagggaatag actcagacgc cggtagagtt gcccgagggc gagaagttgg
      421 ggcaagctga aagtgggggt ctgtcccttc gtaggttttt agacgcatcc cccgtcgacg
      481 gctgcttacc aaccaccagc acctgcgata cctcatccat ttctgtgaat atatttgaag
      541 gcatctttgc aagacggggt cattaaaaca cagacaccac ccctacgttt ccagccattc
      601 caaagtatta ccgacttaat aaatattcac gtttcttgaa ccactaaaaa aaaaaaaaaa
      661 aaa
//
