LOCUS       NM_025796                484 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus mitochondrial ribosomal protein L33 (Mrpl33), mRNA.
ACCESSION   NM_025796
VERSION     NM_025796.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Cheong,A., Lingutla,R. and Mager,J.
  TITLE     Expression analysis of mammalian mitochondrial ribosomal protein
            genes
  JOURNAL   Gene Expr Patterns 38, 119147 (2020)
   PUBMED   32987154
REFERENCE   3  (bases 1 to 484)
  AUTHORS   Greber,B.J. and Ban,N.
  TITLE     Structure and Function of the Mitochondrial Ribosome
  JOURNAL   Annu Rev Biochem 85, 103-132 (2016)
   PUBMED   27023846
  REMARK    Review article
REFERENCE   4  (bases 1 to 484)
  AUTHORS   Brown,A., Amunts,A., Bai,X.C., Sugimoto,Y., Edwards,P.C.,
            Murshudov,G., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Structure of the large ribosomal subunit from human mitochondria
  JOURNAL   Science 346 (6210), 718-722 (2014)
   PUBMED   25278503
REFERENCE   5  (bases 1 to 484)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   6  (bases 1 to 484)
  AUTHORS   Sansom,S.N., Griffiths,D.S., Faedo,A., Kleinjan,D.J., Ruan,Y.,
            Smith,J., van Heyningen,V., Rubenstein,J.L. and Livesey,F.J.
  TITLE     The level of the transcription factor Pax6 is essential for
            controlling the balance between neural stem cell self-renewal and
            neurogenesis
  JOURNAL   PLoS Genet 5 (6), e1000511 (2009)
   PUBMED   19521500
REFERENCE   7  (bases 1 to 484)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   8  (bases 1 to 484)
  AUTHORS   Suzuki,T., Terasaki,M., Takemoto-Hori,C., Hanada,T., Ueda,T.,
            Wada,A. and Watanabe,K.
  TITLE     Structural compensation for the deficit of rRNA with proteins in
            the mammalian mitochondrial ribosome. Systematic analysis of
            protein components of the large ribosomal subunit from mammalian
            mitochondria
  JOURNAL   J Biol Chem 276 (24), 21724-21736 (2001)
   PUBMED   11279069
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY112771.1 and BC055724.1.
            
            On Nov 21, 2009 this sequence version replaced NM_025796.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BU841623.1, BX529022.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-41                BY112771.1         1-41
            42-484              BC055724.1         1-443
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 17.27 cM"
     gene            1..484
                     /gene="Mrpl33"
                     /gene_synonym="0610009M10Rik; L33mt; MRP-L33"
                     /note="mitochondrial ribosomal protein L33"
                     /db_xref="GeneID:66845"
                     /db_xref="MGI:MGI:2137225"
     exon            1..72
                     /gene="Mrpl33"
                     /gene_synonym="0610009M10Rik; L33mt; MRP-L33"
                     /inference="alignment:Splign:2.1.0"
     CDS             51..248
                     /gene="Mrpl33"
                     /gene_synonym="0610009M10Rik; L33mt; MRP-L33"
                     /EC_number="3.6.5.3"
                     /note="39S ribosomal protein L33, mitochondrial"
                     /codon_start=1
                     /product="large ribosomal subunit protein bL33m"
                     /protein_id="NP_080072.2"
                     /db_xref="CCDS:CCDS39056.1"
                     /db_xref="GeneID:66845"
                     /db_xref="MGI:MGI:2137225"
                     /translation="MLLSAVSFAKSKSKTILVKLVSQAGTGFSFNHKRSRLREKLSLL
                     HYDPIVNKKVLFVEQKKIRSL"
     exon            73..91
                     /gene="Mrpl33"
                     /gene_synonym="0610009M10Rik; L33mt; MRP-L33"
                     /inference="alignment:Splign:2.1.0"
     exon            92..198
                     /gene="Mrpl33"
                     /gene_synonym="0610009M10Rik; L33mt; MRP-L33"
                     /inference="alignment:Splign:2.1.0"
     exon            199..466
                     /gene="Mrpl33"
                     /gene_synonym="0610009M10Rik; L33mt; MRP-L33"
                     /inference="alignment:Splign:2.1.0"
     regulatory      440..445
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl33"
                     /gene_synonym="0610009M10Rik; L33mt; MRP-L33"
                     /note="hexamer: AATAAA"
     polyA_site      464
                     /gene="Mrpl33"
                     /gene_synonym="0610009M10Rik; L33mt; MRP-L33"
                     /note="major polyA site"
ORIGIN      
        1 gaagtagtcg ttgagctctt taggcgggtc tcggtgagaa tcggtggacc atgctgctct
       61 ccgctgtctc ttttgccaag agcaagtcaa aaactatcct ggtgaaacta gtgagccaag
      121 ctgggacagg tttctccttc aaccacaaga gaagccgact ccgagagaag ctgagccttc
      181 tgcactatga tccaatagtg aacaaaaaag ttctctttgt ggaacagaaa aaaatccgtt
      241 ccctctgagt agtggattga aaatgaattt gattcctaaa tgagaagctc gagggtgagg
      301 caccgtttcg aactctgcag tgtgcaatga agacgaggaa gttccagcat ggcctcgggg
      361 gatgttggct aagggacaga gccgaaagag tccttcacag agaccacata tttatctccc
      421 tggatgcttt ataggcctta ataaaaaaat atcaaaatag tctataaaaa aaaaaaaaaa
      481 aaaa
//
