LOCUS       NM_053161                828 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus mitochondrial ribosomal protein L27 (Mrpl27), mRNA.
ACCESSION   NM_053161
VERSION     NM_053161.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 828)
  AUTHORS   Cheong,A., Lingutla,R. and Mager,J.
  TITLE     Expression analysis of mammalian mitochondrial ribosomal protein
            genes
  JOURNAL   Gene Expr Patterns 38, 119147 (2020)
   PUBMED   32987154
REFERENCE   2  (bases 1 to 828)
  AUTHORS   Greber,B.J. and Ban,N.
  TITLE     Structure and Function of the Mitochondrial Ribosome
  JOURNAL   Annu Rev Biochem 85, 103-132 (2016)
   PUBMED   27023846
  REMARK    Review article
REFERENCE   3  (bases 1 to 828)
  AUTHORS   Brown,A., Amunts,A., Bai,X.C., Sugimoto,Y., Edwards,P.C.,
            Murshudov,G., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Structure of the large ribosomal subunit from human mitochondria
  JOURNAL   Science 346 (6210), 718-722 (2014)
   PUBMED   25278503
REFERENCE   4  (bases 1 to 828)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   5  (bases 1 to 828)
  AUTHORS   Suzuki,T., Terasaki,M., Takemoto-Hori,C., Hanada,T., Ueda,T.,
            Wada,A. and Watanabe,K.
  TITLE     Structural compensation for the deficit of rRNA with proteins in
            the mammalian mitochondrial ribosome. Systematic analysis of
            protein components of the large ribosomal subunit from mammalian
            mitochondria
  JOURNAL   J Biol Chem 276 (24), 21724-21736 (2001)
   PUBMED   11279069
REFERENCE   6  (bases 1 to 828)
  AUTHORS   Mohlke,K.L., Purkayastha,A.A., Westrick,R.J. and Ginsburg,D.
  TITLE     Comparative mapping of distal murine chromosome 11 and human
            17q21.3 in a region containing a modifying locus for murine plasma
            von Willebrand factor level
  JOURNAL   Genomics 54 (1), 19-30 (1998)
   PUBMED   9806826
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC030074.1.
            
            On Dec 20, 2003 this sequence version replaced NM_053161.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC030074.1, DV047659.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..828
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 58.9 cM"
     gene            1..828
                     /gene="Mrpl27"
                     /gene_synonym="A630055F16Rik; D11Moh47; D18Ertd643e"
                     /note="mitochondrial ribosomal protein L27"
                     /db_xref="GeneID:94064"
                     /db_xref="MGI:MGI:2137224"
     exon            1..51
                     /gene="Mrpl27"
                     /gene_synonym="A630055F16Rik; D11Moh47; D18Ertd643e"
                     /inference="alignment:Splign:2.1.0"
     CDS             12..458
                     /gene="Mrpl27"
                     /gene_synonym="A630055F16Rik; D11Moh47; D18Ertd643e"
                     /note="39S ribosomal protein L27, mitochondrial; L27mt;
                     MRP-L27"
                     /codon_start=1
                     /product="large ribosomal subunit protein bL27m"
                     /protein_id="NP_444391.1"
                     /db_xref="CCDS:CCDS25263.1"
                     /db_xref="GeneID:94064"
                     /db_xref="MGI:MGI:2137224"
                     /translation="MAAAALTLRTRAAVTALLSPTAPTALAVRHASKKTGGSSKNLGG
                     KSRGKHYGIKKMEGHYVHAGNILGTQRQFRWHPGAHVGLGRNKCLYALEEGIVRYTKD
                     VYVPNPKNTEAVDLVTSLPKGAVLYKTFVHVVPAKPEGTFKLVDML"
     exon            52..183
                     /gene="Mrpl27"
                     /gene_synonym="A630055F16Rik; D11Moh47; D18Ertd643e"
                     /inference="alignment:Splign:2.1.0"
     exon            184..251
                     /gene="Mrpl27"
                     /gene_synonym="A630055F16Rik; D11Moh47; D18Ertd643e"
                     /inference="alignment:Splign:2.1.0"
     exon            252..730
                     /gene="Mrpl27"
                     /gene_synonym="A630055F16Rik; D11Moh47; D18Ertd643e"
                     /inference="alignment:Splign:2.1.0"
     regulatory      698..703
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl27"
                     /gene_synonym="A630055F16Rik; D11Moh47; D18Ertd643e"
                     /note="hexamer: TATAAA"
     regulatory      711..716
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl27"
                     /gene_synonym="A630055F16Rik; D11Moh47; D18Ertd643e"
                     /note="hexamer: AATAAA"
     polyA_site      716
                     /gene="Mrpl27"
                     /gene_synonym="A630055F16Rik; D11Moh47; D18Ertd643e"
                     /note="major polyA site"
     polyA_site      730
                     /gene="Mrpl27"
                     /gene_synonym="A630055F16Rik; D11Moh47; D18Ertd643e"
                     /note="major polyA site"
ORIGIN      
        1 gtgaagcaaa tatggcggcg gcggcgctta cgctgaggac gcgggcagca gtgacagccc
       61 tgctgagccc cacagcaccc acagcactcg ctgtcagaca tgcatccaag aagacaggtg
      121 gcagctctaa gaaccttggt gggaaatcac gaggcaaaca ctacggcatc aagaaaatgg
      181 aaggtcacta cgttcacgct ggcaacatcc ttggcactca gcgtcagttt agatggcacc
      241 cgggagccca tgtggggctt gggaggaaca agtgcctgta tgccctggag gaggggatag
      301 tccgctacac gaaagatgtc tacgtgccca atcccaaaaa cacggaggct gtggatctgg
      361 tcactagtct gcccaagggt gctgtgctct acaagacttt tgtccacgtg gttcctgcca
      421 aacctgaggg aaccttcaaa ctagtggaca tgctttgaag tcctgttgag accattggat
      481 ggagcctgga gcccaggtca caggaacagt gatgatggaa gtcaagggtc tgggtgagaa
      541 caaaatctcc acagaagagg ctggagagat ggctcagcag ttaagagcac tgactgctct
      601 tccagaggtc ctgagttcaa ttcccaacaa ccacatggtg gctcacaacc atctataatc
      661 tcttcttgtg tgtctgaaga cagcaacaat gtatgcgtat aaacaaaata aataaatatt
      721 ttaaaaaaga aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
      781 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//
