LOCUS       NM_001417211             600 bp    mRNA    linear   ROD 07-AUG-2024
DEFINITION  Mus musculus mitochondrial ribosomal protein L23 (Mrpl23),
            transcript variant 5, mRNA.
ACCESSION   NM_001417211
VERSION     NM_001417211.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 600)
  AUTHORS   Tomar,A., Gomez-Velazquez,M., Gerlini,R., Comas-Armangue,G.,
            Makharadze,L., Kolbe,T., Boersma,A., Dahlhoff,M., Burgstaller,J.P.,
            Lassi,M., Darr,J., Toppari,J., Virtanen,H., Kuhnapfel,A.,
            Scholz,M., Landgraf,K., Kiess,W., Vogel,M., Gailus-Durner,V.,
            Fuchs,H., Marschall,S., Hrabe de Angelis,M., Kotaja,N., Korner,A.
            and Teperino,R.
  TITLE     Epigenetic inheritance of diet-induced and sperm-borne
            mitochondrial RNAs
  JOURNAL   Nature 630 (8017), 720-727 (2024)
   PUBMED   38839949
REFERENCE   2  (bases 1 to 600)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 600)
  AUTHORS   Cheong,A., Lingutla,R. and Mager,J.
  TITLE     Expression analysis of mammalian mitochondrial ribosomal protein
            genes
  JOURNAL   Gene Expr Patterns 38, 119147 (2020)
   PUBMED   32987154
REFERENCE   4  (bases 1 to 600)
  AUTHORS   Greber,B.J. and Ban,N.
  TITLE     Structure and Function of the Mitochondrial Ribosome
  JOURNAL   Annu Rev Biochem 85, 103-132 (2016)
   PUBMED   27023846
  REMARK    Review article
REFERENCE   5  (bases 1 to 600)
  AUTHORS   Lewandowski,J.P., Du,F., Zhang,S., Powell,M.B., Falkenstein,K.N.,
            Ji,H. and Vokes,S.A.
  TITLE     Spatiotemporal regulation of GLI target genes in the mammalian limb
            bud
  JOURNAL   Dev Biol 406 (1), 92-103 (2015)
   PUBMED   26238476
REFERENCE   6  (bases 1 to 600)
  AUTHORS   Ishihara,K., Kato,R., Furuumi,H., Zubair,M. and Sasaki,H.
  TITLE     Sequence of a 42-kb mouse region containing the imprinted H19
            locus: identification of a novel muscle-specific transcription unit
            showing biallelic expression
  JOURNAL   Mamm Genome 9 (9), 775-777 (1998)
   PUBMED   9716667
REFERENCE   7  (bases 1 to 600)
  AUTHORS   Paulsen,M., Davies,K.R., Bowden,L.M., Villar,A.J., Franck,O.,
            Fuermann,M., Dean,W.L., Moore,T.F., Rodrigues,N., Davies,K.E.,
            Hu,R.J., Feinberg,A.P., Maher,E.R., Reik,W. and Walter,J.
  TITLE     Syntenic organization of the mouse distal chromosome 7 imprinting
            cluster and the Beckwith-Wiedemann syndrome region in chromosome
            11p15.5
  JOURNAL   Hum Mol Genet 7 (7), 1149-1159 (1998)
   PUBMED   9618174
REFERENCE   8  (bases 1 to 600)
  AUTHORS   Greally,J.M., Starr,D.J., Hwang,S., Song,L., Jaarola,M. and
            Zemel,S.
  TITLE     The mouse H19 locus mediates a transition between imprinted and
            non-imprinted DNA replication patterns
  JOURNAL   Hum Mol Genet 7 (1), 91-95 (1998)
   PUBMED   9384608
REFERENCE   9  (bases 1 to 600)
  AUTHORS   Zubair,M., Hilton,K., Saam,J.R., Surani,M.A., Tilghman,S.M. and
            Sasaki,H.
  TITLE     Structure and expression of the mouse L23mrp gene downstream of the
            imprinted H19 gene: biallelic expression and lack of interaction
            with the H19 enhancers
  JOURNAL   Genomics 45 (2), 290-296 (1997)
   PUBMED   9344651
REFERENCE   10 (bases 1 to 600)
  AUTHORS   Greally,J.M., Guinness,M.E., McGrath,J. and Zemel,S.
  TITLE     Matrix-attachment regions in the mouse chromosome 7F imprinted
            domain
  JOURNAL   Mamm Genome 8 (11), 805-810 (1997)
   PUBMED   9337391
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL603651.14 and AC013548.13.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13861894.3521484.1,
                                           SRR15390195.4793.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-91                AL603651.14        2152-2242           c
            92-214              AL603651.14        266-388             c
            215-297             AC013548.13        179270-179352       c
            298-371             AC013548.13        178082-178155       c
            372-600             AC013548.13        174675-174903       c
FEATURES             Location/Qualifiers
     source          1..600
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 87.95 cM"
     gene            1..600
                     /gene="Mrpl23"
                     /gene_synonym="L23mrp; Rpl23; Rpl23l"
                     /note="mitochondrial ribosomal protein L23"
                     /db_xref="GeneID:19935"
                     /db_xref="MGI:MGI:1196612"
     exon            1..91
                     /gene="Mrpl23"
                     /gene_synonym="L23mrp; Rpl23; Rpl23l"
                     /inference="alignment:Splign:2.1.0"
     exon            92..214
                     /gene="Mrpl23"
                     /gene_synonym="L23mrp; Rpl23; Rpl23l"
                     /inference="alignment:Splign:2.1.0"
     CDS             210..515
                     /gene="Mrpl23"
                     /gene_synonym="L23mrp; Rpl23; Rpl23l"
                     /note="isoform 5 is encoded by transcript variant 5; 39S
                     ribosomal protein L23, mitochondrial; L23mt; MRP-L23; L23
                     mitochondrial-related protein; large ribosomal subunit
                     protein uL23m"
                     /codon_start=1
                     /product="large ribosomal subunit protein uL23m isoform 5"
                     /protein_id="NP_001404140.1"
                     /db_xref="GeneID:19935"
                     /db_xref="MGI:MGI:1196612"
                     /translation="MEMTRVDLRNYLEQIYNVPVAAVRTRVQHGSNRRRDHKNVRIKK
                     PDYKVAYVQLAHGQTFTFPDLFPEKDPRSPEPLEEELPQQRQSSDLRCPGIPSWFGL"
     exon            215..297
                     /gene="Mrpl23"
                     /gene_synonym="L23mrp; Rpl23; Rpl23l"
                     /inference="alignment:Splign:2.1.0"
     exon            298..371
                     /gene="Mrpl23"
                     /gene_synonym="L23mrp; Rpl23; Rpl23l"
                     /inference="alignment:Splign:2.1.0"
     exon            372..600
                     /gene="Mrpl23"
                     /gene_synonym="L23mrp; Rpl23; Rpl23l"
                     /inference="alignment:Splign:2.1.0"
     regulatory      576..581
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl23"
                     /gene_synonym="L23mrp; Rpl23; Rpl23l"
                     /note="hexamer: AATAAA"
     polyA_site      600
                     /gene="Mrpl23"
                     /gene_synonym="L23mrp; Rpl23; Rpl23l"
                     /note="major polyA site"
ORIGIN      
        1 ccttcctgac caggaggtgc ggctgccatg gcgcggaatg tgttgtgagt aaagtcgtga
       61 cccgcggaac gggctaagca gcccaggtcg ggtaccccct ttaccaactg ggtggccccc
      121 agctccgtgt atttcgaact aacttcttca ttcagctggt gcggcctggt actgcacagc
      181 ctgaagatac cgtgcagttc cggatcccca tggagatgac cagggtggac cttcggaatt
      241 accttgagca gatttacaat gttcccgtgg ctgccgtgcg cacacgggtg cagcatggct
      301 ccaacaggag gagggatcac aagaatgtga ggatcaagaa accagactac aaagtggcct
      361 acgtgcagct ggcccatggg cagaccttca ctttcccaga tctttttcca gagaaggacc
      421 cccgttctcc agaacctctg gaagaggagc taccccagca gaggcaaagc agcgacctga
      481 ggtgccctgg tatcccttcc tggtttggcc tatgacctat gacagcagga tttggaccac
      541 agaccctagt gagcacagtg gttctgacaa gcccaaataa aaattctttg tggagaaaga
//
