LOCUS       NM_001347420             836 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus mitochondrial ribosomal protein L21 (Mrpl21),
            transcript variant 2, mRNA.
ACCESSION   NM_001347420 XM_006531777
VERSION     NM_001347420.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 836)
  AUTHORS   Cheong,A., Lingutla,R. and Mager,J.
  TITLE     Expression analysis of mammalian mitochondrial ribosomal protein
            genes
  JOURNAL   Gene Expr Patterns 38, 119147 (2020)
   PUBMED   32987154
REFERENCE   2  (bases 1 to 836)
  AUTHORS   Greber,B.J. and Ban,N.
  TITLE     Structure and Function of the Mitochondrial Ribosome
  JOURNAL   Annu Rev Biochem 85, 103-132 (2016)
   PUBMED   27023846
  REMARK    Review article
REFERENCE   3  (bases 1 to 836)
  AUTHORS   Brown,A., Amunts,A., Bai,X.C., Sugimoto,Y., Edwards,P.C.,
            Murshudov,G., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Structure of the large ribosomal subunit from human mitochondria
  JOURNAL   Science 346 (6210), 718-722 (2014)
   PUBMED   25278503
REFERENCE   4  (bases 1 to 836)
  AUTHORS   Easterday,M.C., Dougherty,J.D., Jackson,R.L., Ou,J., Nakano,I.,
            Paucar,A.A., Roobini,B., Dianati,M., Irvin,D.K., Weissman,I.L.,
            Terskikh,A.V., Geschwind,D.H. and Kornblum,H.I.
  TITLE     Neural progenitor genes. Germinal zone expression and analysis of
            genetic overlap in stem cell populations
  JOURNAL   Dev Biol 264 (2), 309-322 (2003)
   PUBMED   14651920
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL626765.22, BC028768.1 and AW050299.1.
            
            On Mar 13, 2018 this sequence version replaced NM_001347420.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB195624.1, BC028768.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-30                AL626765.22        65835-65864
            31-816              BC028768.1         1-786
            817-836             AW050299.1         1-20                c
FEATURES             Location/Qualifiers
     source          1..836
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 3.05 cM"
     gene            1..836
                     /gene="Mrpl21"
                     /gene_synonym="L21mt; MRP-L21"
                     /note="mitochondrial ribosomal protein L21"
                     /db_xref="GeneID:353242"
                     /db_xref="MGI:MGI:2660674"
     exon            1..130
                     /gene="Mrpl21"
                     /gene_synonym="L21mt; MRP-L21"
                     /inference="alignment:Splign:2.1.0"
     CDS             31..660
                     /gene="Mrpl21"
                     /gene_synonym="L21mt; MRP-L21"
                     /note="isoform 2 is encoded by transcript variant 2; 39S
                     ribosomal protein L21, mitochondrial; large ribosomal
                     subunit protein bL21m"
                     /codon_start=1
                     /product="large ribosomal subunit protein bL21m isoform 2"
                     /protein_id="NP_001334349.1"
                     /db_xref="CCDS:CCDS84406.1"
                     /db_xref="GeneID:353242"
                     /db_xref="MGI:MGI:2660674"
                     /translation="MAAAIAASALPGAFGRLVSVCSRSILASQGSGSASLWSASRRFN
                     SQSASYPQGYVPKTSLSSPPWQEVVLPDPVEETRHHAEVVKRVNELIATGQYGRLFAV
                     VHFASHQWKVTAEDLILIENELDIKCGERIRLEKVLLVGADNFTLLGKPLLRKELVRV
                     EATVIEKTESWPKINMKFRKRKNFRKKKIIVNPQTILRINTIEIAPRLL"
     exon            131..188
                     /gene="Mrpl21"
                     /gene_synonym="L21mt; MRP-L21"
                     /inference="alignment:Splign:2.1.0"
     exon            189..274
                     /gene="Mrpl21"
                     /gene_synonym="L21mt; MRP-L21"
                     /inference="alignment:Splign:2.1.0"
     exon            275..438
                     /gene="Mrpl21"
                     /gene_synonym="L21mt; MRP-L21"
                     /inference="alignment:Splign:2.1.0"
     exon            439..491
                     /gene="Mrpl21"
                     /gene_synonym="L21mt; MRP-L21"
                     /inference="alignment:Splign:2.1.0"
     exon            492..595
                     /gene="Mrpl21"
                     /gene_synonym="L21mt; MRP-L21"
                     /inference="alignment:Splign:2.1.0"
     exon            596..820
                     /gene="Mrpl21"
                     /gene_synonym="L21mt; MRP-L21"
                     /inference="alignment:Splign:2.1.0"
     regulatory      796..801
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl21"
                     /gene_synonym="L21mt; MRP-L21"
                     /note="hexamer: AATAAA"
     polyA_site      814
                     /gene="Mrpl21"
                     /gene_synonym="L21mt; MRP-L21"
                     /note="major polyA site"
ORIGIN      
        1 gcttccgctt ccggttggga ctgtggaaac atggctgctg ccatagcggc ctcggcattg
       61 ccgggcgcct tcgggcggct ggtgtctgtg tgtagccgta gcatcttggc atcccaggga
      121 tccggatcag cctccctctg gtctgcttct cgaaggttca attcacagag cgcttcatat
      181 ccacaaggat atgttcctaa gacctccctg agctcaccac cctggcaaga agtggttctg
      241 ccggaccctg ttgaagagac gagacaccat gcggaggttg tgaagagggt gaatgagctg
      301 atcgccacgg gccagtatgg ccggctcttt gctgtcgtgc actttgccag ccaccaatgg
      361 aaggtgaccg cagaggacct gattctaatt gaaaatgagt tggatatcaa gtgtggagag
      421 aggattcggc tggagaaggt cctgctggtt ggggcagaca acttcacact cctgggcaag
      481 ccactcctcc gaaaggagct tgtacgagtt gaagccacag tcattgaaaa gacagaatca
      541 tggcccaaaa tcaacatgaa atttaggaaa aggaaaaact tcaggaagaa aaaaatcatt
      601 gtgaaccctc agaccatcct ccgcattaac accattgaga ttgcacctcg tttgctgtga
      661 ctgcagagcc gatgtctaag aagttctgaa atgtctaata aattcacgtc tgtactcagg
      721 aagctgaggc aggaggatca caagttccag gctaggttgg gctacaaagc aagaccttgt
      781 ctgacaatga aaacaaataa agtatttttt aggagactga aaaaaaaaaa aaaaaa
//
