LOCUS       NM_025570               1151 bp    mRNA    linear   ROD 06-JUN-2024
DEFINITION  Mus musculus mitochondrial ribosomal protein L20 (Mrpl20), mRNA.
ACCESSION   NM_025570 XM_006539104
VERSION     NM_025570.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1151)
  AUTHORS   Cheong,A., Lingutla,R. and Mager,J.
  TITLE     Expression analysis of mammalian mitochondrial ribosomal protein
            genes
  JOURNAL   Gene Expr Patterns 38, 119147 (2020)
   PUBMED   32987154
REFERENCE   2  (bases 1 to 1151)
  AUTHORS   Greber,B.J. and Ban,N.
  TITLE     Structure and Function of the Mitochondrial Ribosome
  JOURNAL   Annu Rev Biochem 85, 103-132 (2016)
   PUBMED   27023846
  REMARK    Review article
REFERENCE   3  (bases 1 to 1151)
  AUTHORS   Brown,A., Amunts,A., Bai,X.C., Sugimoto,Y., Edwards,P.C.,
            Murshudov,G., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Structure of the large ribosomal subunit from human mitochondria
  JOURNAL   Science 346 (6210), 718-722 (2014)
   PUBMED   25278503
REFERENCE   4  (bases 1 to 1151)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   5  (bases 1 to 1151)
  AUTHORS   Berke,J.D., Sgambato,V., Zhu,P.P., Lavoie,B., Vincent,M., Krause,M.
            and Hyman,S.E.
  TITLE     Dopamine and glutamate induce distinct striatal splice forms of
            Ania-6, an RNA polymerase II-associated cyclin
  JOURNAL   Neuron 32 (2), 277-287 (2001)
   PUBMED   11683997
REFERENCE   6  (bases 1 to 1151)
  AUTHORS   Suzuki,T., Terasaki,M., Takemoto-Hori,C., Hanada,T., Ueda,T.,
            Wada,A. and Watanabe,K.
  TITLE     Structural compensation for the deficit of rRNA with proteins in
            the mammalian mitochondrial ribosome. Systematic analysis of
            protein components of the large ribosomal subunit from mammalian
            mitochondria
  JOURNAL   J Biol Chem 276 (24), 21724-21736 (2001)
   PUBMED   11279069
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL670236.9, CJ082585.1, AK011341.1 and BC039985.1.
            
            On or before Sep 19, 2017 this sequence version replaced
            XM_006539104.2, NM_025570.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.1531468.1,
                                           ERR2680377.995429.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-218               AL670236.9         109468-109685
            219-522             CJ082585.1         56-359
            523-1128            AK011341.1         61-666
            1129-1151           BC039985.1         636-658
FEATURES             Location/Qualifiers
     source          1..1151
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 87.44 cM"
     gene            1..1151
                     /gene="Mrpl20"
                     /gene_synonym="2610008D01Rik; 4930425I20Rik"
                     /note="mitochondrial ribosomal protein L20"
                     /db_xref="GeneID:66448"
                     /db_xref="MGI:MGI:2137221"
     exon            1..218
                     /gene="Mrpl20"
                     /gene_synonym="2610008D01Rik; 4930425I20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            219..588
                     /gene="Mrpl20"
                     /gene_synonym="2610008D01Rik; 4930425I20Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             502..951
                     /gene="Mrpl20"
                     /gene_synonym="2610008D01Rik; 4930425I20Rik"
                     /note="39S ribosomal protein L20, mitochondrial; L20mt;
                     MRP-L20; large ribosomal subunit protein bL20m"
                     /codon_start=1
                     /product="large ribosomal subunit protein bL20m precursor"
                     /protein_id="NP_079846.1"
                     /db_xref="CCDS:CCDS19041.1"
                     /db_xref="GeneID:66448"
                     /db_xref="MGI:MGI:2137221"
                     /translation="MVFLTTRLWLRNRLTDRYWRVQEVLKHAQHFRGRKNRCYRLAVR
                     AVTRAFVKCTKARRLKKRNLRTLWINRITAASQEHGLKYPAFIVNLIKCQVELNRKVL
                     VDLAIYEPKTFKSLAALAKRRQQEGFAAALGDGKEPEGIFSRVVQYH"
     exon            589..699
                     /gene="Mrpl20"
                     /gene_synonym="2610008D01Rik; 4930425I20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            700..777
                     /gene="Mrpl20"
                     /gene_synonym="2610008D01Rik; 4930425I20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            778..1130
                     /gene="Mrpl20"
                     /gene_synonym="2610008D01Rik; 4930425I20Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1108..1113
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl20"
                     /gene_synonym="2610008D01Rik; 4930425I20Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1130
                     /gene="Mrpl20"
                     /gene_synonym="2610008D01Rik; 4930425I20Rik"
                     /note="major polyA site"
ORIGIN      
        1 ctgtcagtgc tcttaaccct ctctccagcc ccaattctgc tgagttgact gcgagtccca
       61 ctccgactgt cagcttcgcc ttcatctcgg tagagcttgt atctcccaca gctccaggag
      121 ctcagccctc caccccccga aacttggcct ctgtacctgc gggaggttgg gctccatccc
      181 caggatacat cttcaggaca gtagatacct ttgttcatgg tcaactgatg cccacagaag
      241 agcggaccac cgagtgttcc ttggcggttt ctgtagatct gatttccgtc cgggactgct
      301 cgccatcccc gcccgcgggg cttcctccag tttatgctct aaccattctc ccgcgtgcgg
      361 acggtctggc acaacggaac tgagggagcg agtctagagg cgccccggaa gacagtgctc
      421 gcacacatcc ggcagggctg gcctgtctga ccgttgaccc ggaagcgctt ctggcagccg
      481 gtcgggcttc gggagcccat catggtcttc ctcacgacgc ggctctggct gcggaaccgc
      541 ctcaccgatc gctattggcg ggttcaggag gtgctgaaac acgctcagca ttttcgggga
      601 aggaagaatc gctgctaccg cctggccgtc agggcggtga ccagagcctt cgttaagtgt
      661 acgaaggccc gcagacttaa gaagcggaac ctgaggaccc tctggattaa tcgaattaca
      721 gctgcctccc aggaacatgg cttaaagtac ccagcattca ttgtcaactt aattaagtgc
      781 caggtggagc tcaacaggaa agttcttgtg gacctggcca tctatgaacc aaagacgttt
      841 aaatctttgg ctgcattggc taagcggagg cagcaggagg gatttgctgc agctttgggg
      901 gatggaaagg agcctgaagg tatcttttcc agagtggtgc agtaccactg aaggctgcag
      961 tgctatagac tgttataaac aagataggac caaaaggact gtcaccagta agtctgattt
     1021 gtatttattt acattttagc aacaggcctg agacgacagg tctttattca gtgacacggc
     1081 cccaaactgt cctgtaaaga ttgtataaat aaagcctttg cagtgttgaa aaaaaaaaaa
     1141 aaaaaaaaaa a
//
