LOCUS       NM_026490               5016 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus mitochondrial ribosomal protein L19 (Mrpl19), mRNA.
ACCESSION   NM_026490
VERSION     NM_026490.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5016)
  AUTHORS   Cheong,A., Lingutla,R. and Mager,J.
  TITLE     Expression analysis of mammalian mitochondrial ribosomal protein
            genes
  JOURNAL   Gene Expr Patterns 38, 119147 (2020)
   PUBMED   32987154
REFERENCE   2  (bases 1 to 5016)
  AUTHORS   Greber,B.J. and Ban,N.
  TITLE     Structure and Function of the Mitochondrial Ribosome
  JOURNAL   Annu Rev Biochem 85, 103-132 (2016)
   PUBMED   27023846
  REMARK    Review article
REFERENCE   3  (bases 1 to 5016)
  AUTHORS   Brown,A., Amunts,A., Bai,X.C., Sugimoto,Y., Edwards,P.C.,
            Murshudov,G., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Structure of the large ribosomal subunit from human mitochondria
  JOURNAL   Science 346 (6210), 718-722 (2014)
   PUBMED   25278503
REFERENCE   4  (bases 1 to 5016)
  AUTHORS   Graack,H.R., Bryant,M.L. and O'Brien,T.W.
  TITLE     Identification of mammalian mitochondrial ribosomal proteins (MRPs)
            by N-terminal sequencing of purified bovine MRPs and comparison to
            data bank sequences: the large subribosomal particle
  JOURNAL   Biochemistry 38 (50), 16569-16577 (1999)
   PUBMED   10600119
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK018508.1 and AC129024.4.
            
            On Jul 8, 2005 this sequence version replaced NM_026490.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC061064.1, AK050637.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1132              AK018508.1         2-1133
            1133-5016           AC129024.4         48639-52522
FEATURES             Location/Qualifiers
     source          1..5016
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 35.81 cM"
     gene            1..5016
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
                     /note="mitochondrial ribosomal protein L19"
                     /db_xref="GeneID:56284"
                     /db_xref="MGI:MGI:1926274"
     exon            1..243
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
                     /inference="alignment:Splign:2.1.0"
     CDS             23..901
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
                     /note="39S ribosomal protein L19, mitochondrial; L19mt;
                     MRP-L19; ribosomal protein, mitochondrial, L15"
                     /codon_start=1
                     /product="large ribosomal subunit protein bL19m"
                     /protein_id="NP_080766.1"
                     /db_xref="CCDS:CCDS39523.1"
                     /db_xref="GeneID:56284"
                     /db_xref="MGI:MGI:1926274"
                     /translation="MAASMAESCRASLYLARSVRMARPRLAAFASDACRVCTGPSRFQ
                     STGPSEPGGFKPPPKPVIVDRRRVPEDERRFLSPEFIPPRGRTNPLKFKIERKDMLDR
                     RKVLPIPEFYVGSILRVTTADPYASGKTSQFLGICIKRSGNGLGATFTLRNTIEGQGV
                     EICFELYNPRIQEIQVVKLEKRLDDNLLYLRDALPEYSTFDVNMKPVPQEACQEVPVN
                     KLKVKMKPKPWSKRWERPNFNIKGIRFDLALTEEQMKEAQKWNKPWIEFDMMREYDTS
                     KIEAALWEEIEASKKS"
     exon            244..362
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
                     /inference="alignment:Splign:2.1.0"
     exon            363..497
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
                     /inference="alignment:Splign:2.1.0"
     exon            498..679
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
                     /inference="alignment:Splign:2.1.0"
     exon            680..5016
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1355..1360
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
                     /note="hexamer: ATTAAA"
     polyA_site      1387
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
                     /note="major polyA site"
     regulatory      3183..3188
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
                     /note="hexamer: AATAAA"
     polyA_site      3211
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
     regulatory      3776..3781
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
                     /note="hexamer: AATAAA"
     polyA_site      3804
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
     regulatory      3868..3873
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
                     /note="hexamer: AATAAA"
     regulatory      3872..3877
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
                     /note="hexamer: AATACA"
     polyA_site      3890
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
     regulatory      3902..3907
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
                     /note="hexamer: AATATA"
     polyA_site      3903
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
     regulatory      3920..3925
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
                     /note="hexamer: AATACA"
     polyA_site      3929
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
     polyA_site      3940
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
     regulatory      4278..4283
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
                     /note="hexamer: AATAAA"
     polyA_site      4300
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
     regulatory      4612..4617
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
                     /note="hexamer: AGTAAA"
     polyA_site      4632
                     /gene="Mrpl19"
                     /gene_synonym="9030416F12Rik; 9130412E02Rik; D6Ertd157e;
                     MRP-L15; RLX1; Rpml15"
ORIGIN      
        1 gtccttcatt gagggtgtag acatggcggc ctccatggca gaaagttgta gggcgtccct
       61 gtacctggcc cggagcgtcc gaatggccag gccacggctt gctgccttcg catctgatgc
      121 ctgccgtgtc tgcacgggcc caagccgatt tcagagcacc gggccttcag agcccggtgg
      181 gttcaagcca ccgccgaaac ctgtcatcgt ggaccggcgc cgagtcccgg aagacgagag
      241 aaggttcctg agtcctgaat tcatccctcc cagggggaga acaaaccctc tgaaatttaa
      301 gatagaaaga aaagatatgc tagacaggag aaaggtgctt ccgattccag agttctatgt
      361 tggaagcata cttcgagtca ccacagccga cccctatgcc agtggaaaaa ccagccagtt
      421 cctggggatt tgcatcaagc gatcagggaa tgggctcggg gctactttca ccctcaggaa
      481 cacgattgaa ggacaaggtg tggagatttg ctttgaactg tataatcctc gaatccagga
      541 gatccaggtg gtgaagttgg agaagcggct ggatgacaac ctgctgtact tacgggacgc
      601 ccttcccgag tacagcacct ttgacgtgaa catgaagccg gtcccacagg aggcctgcca
      661 ggaagtgcct gttaacaagc tgaaagttaa aatgaagcca aagccgtggt ccaaacgctg
      721 ggaacgtcca aacttcaaca ttaagggaat cagatttgac cttgctttaa ctgaagagca
      781 aatgaaggaa gcccagaagt ggaacaagcc atggattgag tttgatatga tgagagaata
      841 tgacacttca aaaattgaag ctgcattgtg ggaagaaata gaagcatcga agaagtcttg
      901 atcctgggac tagtgaatgg ctcaacaggt aaacatgcct gttggctcag gcctgatgcc
      961 ctgaacttga ctctggaacc cagggcggaa ggcgagtaac aactcctaaa agttgccctt
     1021 tggcttctac tgcacatcct tgcgtatgtg tactgcaatt acacacacac ttaaaagtat
     1081 ctttctgccg ggtgtggtgg cgcatgcctt taatcccagc actcgggagg cagaggcagg
     1141 cggatttctg agttcgaggc cagcctggtc tacaaagtga ggtccaggac agccagggct
     1201 atacagagaa accctgtctt gacaaaccaa aaaaaaaaaa aaaaaaaaaa aaaaaagtat
     1261 ctttctttta agcccttgtt ctgagaatgc ctttggttaa tgtattagct ctttggtttg
     1321 aaagccatta agtttgcttt gtaaggacat agtgattaaa tgagcattcc tcacttttcg
     1381 gtacctagca taaagtctgc atgtcagttt attgctctca aaagagcaat cacctgacag
     1441 tcattccctt tctatagcca gtgaagttag catcaccaga ataagatgaa ctgggatctg
     1501 agcaagagga gtagggaaaa aaccataaac acacaacagt gtgcaagtta aaatgtaaga
     1561 ataggagctg tagaggtggc tcagtagttc agagcacttg ctactcttgc agaggcccta
     1621 cgtttagttc ctagcaccca ggcctgtatg tgtgtacatg gttccagaga ccaggaagta
     1681 tcagactgcc tggaactgga gttacagctg cttatgacac aggtggtagt ttgaatatgc
     1741 ttggcccata tggagtggta ctgttaggaa gtgtggccgt gttggatgaa gtatgtcacg
     1801 gtgggggtgg gctttgcggt ctcatgttca agtgtggtca gcgtcagact ctcctagctg
     1861 tagttggatc aagatgcaga actctcagcc gtgtgtctgc ctggacactt ccatgatgtt
     1921 aatggactga agctctgata ctgttaagcc agccctaatt caatgttgtc ccttatgaga
     1981 gttgccttag tcgtggtgtc tcgtcacagc aatgaaaccc cagctaacac aacccacctg
     2041 ataatctctc cattgttaaa tgtctagttt tgacaggctc attagctggt agaaaagggt
     2101 cctgttttgc tacatggcag ttttaagaag aatgtgggaa tctgagttgt tgtattctgg
     2161 cttcatttcc cccaagttta caaaagccac ttgtgaggaa ttccatgggt agaattccaa
     2221 gtgaagtctg ctaagcagac ctcagggtac ctggcagagc ctgtgtgaac tgggtgtgaa
     2281 tgtccagcag gaagatggtc agagagtgtt atcttcccta tgaatcaagc ttcagctttt
     2341 gggggtcagc actccctcta gtggggcaga gtgcagctga acatgggctg ggaagctggg
     2401 atgcctcaca gagtaaaggc taacccattt gtaacatcac agtgccagcc tggatctcag
     2461 gactattttt ctggtgagct gctctgcatt ccgtgtcatt ttcctggctg ctaactcctt
     2521 aattattcta gtttccagag atgtgcatgt gtgtggaccg ccatgggcat acatatacct
     2581 catgatcagg ctcaggagtc ctttcagtca cgttggccac gttttactct tgagagagac
     2641 tgtactatct ggcctgtact ctctctcttc tctgaggtct ccatgctaca gagtctactt
     2701 gaatagtttt agtgctgcat tgagaaaccc agcgtcgtcc gggtttctgc tccttgggca
     2761 tgactggaca gcagagaacg tgtgctgtgc ttggtgcacg ggcaggtaca tttatctacc
     2821 tagtttaggg ctgtgggtaa gcctctcagt gctgactcga gttctgggag acttggctct
     2881 tgctgctgag tttctctcct ctgcttctgt cttcctggaa ccattatttg gagtttagat
     2941 gctgagtacc tcttttctat ttaagtgcat gcttgtgtga ctgcatcaga cccccgggag
     3001 ctggagttac aggtggttgt gagccacctg gtgtgggtgc tgggaaggga atgccactga
     3061 gtctgtccag tctctgagac acacacaggt ctcccgatag acctgtctgt gtgggtgggt
     3121 agaaagggcc ctaggctgtt ctcctgtatg cttcattttc ctgaacctgt ttcagtgttg
     3181 acaataaatt catgagtcag ttgaaggaga ataagacttt acctaaaatt agttttctaa
     3241 ctcacgaaca cggtgtctct gcagttaggc cttttaagtt cccctctcca ggtgtggtaa
     3301 tccaaaggct tgggaggcag aggcaggagg gttccaagat cagtgtcacg tacacttcag
     3361 aatgagaccc agtctccaca aaagaaacca tcagagatgg acagtgaaag tttgttgttt
     3421 ctggttctta agtttttgtc gtggtctcat gaagccccag ctggcccgca gctcactggg
     3481 tctgtgagac gaatcaccag gtgagtgtgt gcacctgttg tgtcagcgcc ttcatttcac
     3541 aggaccagga ggaacgagta agaactctaa aagggcagta gagttagcat cacaatatgt
     3601 tttaaagacg cttggaagct cacatgccag gcgtaatgga atttaaaggc gatagcttac
     3661 tactctgcat cccatgaaga agagagatga tgaccgagag cacagccatc cacacgtcca
     3721 tctcgaagaa gccaaggcca gagaacagtt tccaaaagtg ccctttaaca gcaaaaataa
     3781 agtctctgcc atttatatac aaaactttct gcacacatat acacatgctt ttgtaacgag
     3841 caaatgtcta aagtgacaac acggaaaaat aaatacagga tcatcattga gttgcttaac
     3901 aaatatactt aagaacatta atacagtcat tttgagaaaa gttcataatt tcttaatcac
     3961 cttgcctcag actaccttaa ttagagaaat actttacatt tctgtattta aaagagcaat
     4021 ggccttttta gtcctaccat gagttacaca aaacatagca aaaaagcctc acttaaggac
     4081 ttacagatga ctcagaccac agcttcattc ttcacaggga gggtgaagat ctcttctgag
     4141 gacctgggtt tggttccaag cacattagat ggcccacaac ctcctggatt ccagttccag
     4201 gggacctgat gccctctggc ccctacatgg aggtagtgct aaacccaccc aggtacatac
     4261 atgaccacac atataaaaat aaatcttttt tcaaagtttt ttttttttta acaaattgac
     4321 aatgaatcaa aatctggaga tcactggcac tctcttgcac tgatttcaca cagtaagtca
     4381 gtacagattt tgaaaggaca gtttgtataa aaatgtgtta gctatttaat aagtaattcc
     4441 ttacacttca gaatgagacc gagtccccac caaagaataa gataaaagaa accatccaga
     4501 gatagagctt cctcattagc tgatctgcaa acattggagt ttgctgaaga tggttttgat
     4561 tcaggcatgc ttctgtgtgt cagattgctt catttccttc cggattgaga gagtaaaaga
     4621 gcagcacact gagctcggct gctgctgtgc attacttccc tcagctacga agcatcagga
     4681 ggcctggcca caccccaagt gggcacccag caaaggcggc atcggctgtg acacggtcat
     4741 cttgactctg ggcactccca cacggcgcac tcaaacacct gtactctggg ctgggagggg
     4801 ctccagggga cgctcttctc tgagggattc ggcttgagtc agagctttta ccttcaccag
     4861 gataagaatt atttcactga cttcattcct gaaaaacaac caaaaagcac ttactctccc
     4921 cttagcagcc aagcgagagg cgcaggagtg gtaaagcctt tagcaggcag tgggccctaa
     4981 atttgatcct tagcaaaaaa aaaaaaaaaa aaaaaa
//
