LOCUS       NM_205810               4185 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus MAS-related GPR, member B1 (Mrgprb1), mRNA.
ACCESSION   NM_205810 XM_133492
VERSION     NM_205810.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4185)
  AUTHORS   Zylka,M.J., Dong,X., Southwell,A.L. and Anderson,D.J.
  TITLE     Atypical expansion in mice of the sensory neuron-specific Mrg G
            protein-coupled receptor family
  JOURNAL   Proc Natl Acad Sci U S A 100 (17), 10043-10048 (2003)
   PUBMED   12909716
REFERENCE   2  (bases 1 to 4185)
  AUTHORS   Han,S.K., Dong,X., Hwang,J.I., Zylka,M.J., Anderson,D.J. and
            Simon,M.I.
  TITLE     Orphan G protein-coupled receptors MrgA1 and MrgC11 are
            distinctively activated by RF-amide-related peptides through the
            Galpha q/11 pathway
  JOURNAL   Proc Natl Acad Sci U S A 99 (23), 14740-14745 (2002)
   PUBMED   12397184
REFERENCE   3  (bases 1 to 4185)
  AUTHORS   Dong,X., Han,S., Zylka,M.J., Simon,M.I. and Anderson,D.J.
  TITLE     A diverse family of GPCRs expressed in specific subsets of
            nociceptive sensory neurons
  JOURNAL   Cell 106 (5), 619-632 (2001)
   PUBMED   11551509
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK148114.1 and AK148279.1.
            
            On Jul 31, 2007 this sequence version replaced NM_205810.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK148279.1, AK148074.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1680              AK148114.1         2-1681
            1681-4185           AK148279.1         1636-4140
FEATURES             Location/Qualifiers
     source          1..4185
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 31.11 cM"
     gene            1..4185
                     /gene="Mrgprb1"
                     /gene_synonym="MrgB1"
                     /note="MAS-related GPR, member B1"
                     /db_xref="GeneID:233231"
                     /db_xref="MGI:MGI:3033115"
     exon            1..146
                     /gene="Mrgprb1"
                     /gene_synonym="MrgB1"
                     /inference="alignment:Splign:2.1.0"
     CDS             136..1188
                     /gene="Mrgprb1"
                     /gene_synonym="MrgB1"
                     /note="MrgB1 G protein-coupled receptor"
                     /codon_start=1
                     /product="mas-related G-protein coupled receptor member
                     B1"
                     /protein_id="NP_991379.3"
                     /db_xref="CCDS:CCDS52257.1"
                     /db_xref="GeneID:233231"
                     /db_xref="MGI:MGI:3033115"
                     /translation="MEQRTEIAPLLKMDLVIQDWTINITALKESNDNGISFCEVVSRT
                     MTFLSLIIALVGLVGNATVLWFLGFQMSRNAFSVYILNLAGADFVFMCFQIVHCFYII
                     LDIYFIPTNFFSSYTMVLNIAYLSGLSILTVISTERFLSVMWPIWYRCQRPRHTSAVI
                     CTVLWVLSLVLSLLEGKECGFLYYTSGPGLCKTFDLITTAWLIVLFVVLLGSSLALVL
                     TIFCGLHKVPVTRLYVTIVFTVLVFLIFGLPYGIYWFLLEWIREFHDNKPCGFRNVTI
                     FLSCINSCANPIIYFLVGSIRHHRFQRKTLKLLLQRAMQDSPEEEECGEMGSSRRPRE
                     IKTVWKGLRAALIRHK"
     exon            147..4185
                     /gene="Mrgprb1"
                     /gene_synonym="MrgB1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3585..3590
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mrgprb1"
                     /gene_synonym="MrgB1"
                     /note="hexamer: AATAAA"
     polyA_site      3612
                     /gene="Mrgprb1"
                     /gene_synonym="MrgB1"
                     /note="major polyA site"
ORIGIN      
        1 ctgacattct gattagcctt catcaggcac cagtcacatt gttatccatg cgctgcagac
       61 gtgtttcata ttgacagctg gttccagtaa ctcttcactt tgacacagag caaattacca
      121 tcttctataa gaaaaatgga gcaaagaact gagattgcac cactcctgaa aatggactta
      181 gtcatccaag actggaccat taatattaca gcactgaaag aaagcaatga caatggaata
      241 tcattttgtg aagttgtgtc tcgtaccatg acttttcttt ccctcatcat tgccttagtt
      301 gggctggttg gaaatgccac agtgttatgg tttctgggct tccagatgag caggaatgcc
      361 ttctctgtct acatcctcaa ccttgctggt gctgactttg tcttcatgtg ctttcaaatt
      421 gtacattgtt tttatattat cttagacatc tacttcatcc ccactaattt tttttcatct
      481 tacactatgg tgttaaacat tgcttacctt agtggtctga gcatcctcac tgtcattagc
      541 actgaacgct tcctatctgt catgtggccc atctggtacc gctgccaacg cccaaggcac
      601 acatcagctg tcatatgtac tgtgctttgg gtcttgtccc tggtgttgag cctcctggaa
      661 ggaaaggaat gtggcttcct atattacact agtggccctg gtttgtgtaa gacatttgat
      721 ttaatcacta ctgcatggtt aattgtttta tttgtggttc tcttgggatc cagtctggcc
      781 ttggtgctta ccatcttctg tggcttacac aaggttcctg tgaccaggtt gtatgtgacc
      841 attgtgttta cagtgcttgt cttcctgatc tttggtctgc cctatgggat ctactggttc
      901 ctcttagagt ggattaggga atttcatgat aataaacctt gtggttttcg taacgtgaca
      961 atatttctgt cctgtattaa cagctgtgcc aaccccatca tttacttcct tgttggctcc
     1021 attaggcacc atcggtttca acggaagact ctcaagcttc ttctgcagag agccatgcaa
     1081 gactctcctg aggaggaaga atgtggagag atgggttcct caagaagacc tagagaaata
     1141 aaaactgtct ggaagggact gagagctgct ttgatcaggc ataaatagct ttgaagagaa
     1201 ctatgttttt atcactttgt ggcattttca taatgttgtt tagttgatga cccaaggtta
     1261 actcagttgg ggaagtagtc aatgttgtag aagttgattg atattgaact tgttataaat
     1321 actgagtaca gtatttttgc agctatcttg ctcagagctt taccaactcc atttgatggg
     1381 actccttata agctctatgg ggtccaggag aggtgttgac cacaattgac aaatccctct
     1441 tcagaagaaa actcaagaaa gtgcaatgaa aagttatatt tctttgctca cttaatttga
     1501 tagtggttaa atccttgtta tactttgcaa aaaaaattct gttttaaaac aaactttttc
     1561 caataatgaa gggctaaata gataagtaat aatcacagaa cttactaatt tctgtaggtt
     1621 ttaataaatg tatgatcatc tttcttatat aaatttctta gtaaagatgt aaacattctc
     1681 aagagaagtc tgttaaatca ctattctccc agtggattcc tcaccttcaa gttcactatc
     1741 tattccattt tcagcattgg aagagtgtgc tcagtctaat aatgtgatcc atcaatatcc
     1801 atgctcatga aaaggttgag agtgtctgtc ctcttttctt cctttcacag tgtcctactt
     1861 agcttcccat ggttgagtgt tgactttgtc atgattctcc ttctctctga ctctttcctc
     1921 atgatatttt tccaatcagg tcctctataa caggttccct tgatatcaaa cttgttttaa
     1981 atttatacca tttcacgagc gagtagcatc taaaaactta attatgtaat gttaagtaaa
     2041 gttttctata aaacagtatt tcaattttaa agctgcagtg tgtgataaat tcaattaaga
     2101 ggatagaata tcaacagatt aatgtaaaaa aaatcaggat tttaagttaa tataggtata
     2161 aaacctaatc aagacacaaa acactctctt atatttctta atttttattt ctcctccagt
     2221 caaaattttt tgtcagaggt aaatatgctg tccatatttt tgttgcaaac taaaatttac
     2281 agtgcaaatt aaagattgta gcatgatgtt tgatatacat gtagctaaat ggttgttata
     2341 gttgaacaaa ctaacatata cagcaggtta tgtaaatatt cattttctcc ttttgcttgg
     2401 cccagtattt cctcaccatg tctccattcc tcttttggaa tggatggtaa tgtacgatct
     2461 gtgcctgtgt atgtgggaaa caagtactgt gcttttttta tttgacaagg agttacaatt
     2521 aagagattgc cttgagtatc ataagagact tttgactttt aaactgtgtt tgtactgtga
     2581 aagactatga gaacttttca agttggattt agtgtgtttt ctactgtgat atagctacaa
     2641 atttacatgg tccaagaact ggaatgtggt ggtgtacctg aaaaatttcc tctacagtct
     2701 cattttggaa ttcttggccc cagattggtg gaactgtttg ggatggatta aaatgtgtgt
     2761 cctttttgga atatatctca gtaggggtaa tctttgaggt ttcaaaagcc agtactattc
     2821 cacatcagcc ctttatctgc ctcaagcttg agagtcagat ataagcttct ggcaactgct
     2881 ccattgccat gccaacctgt ctgcctcttc tcaggcttct ggctatgagg gtcatgtatt
     2941 ccaccccatg agaattatga catatcttat gaaatatttt gtatgagtag actttgttat
     3001 cacagcaaca gaaaaataat tatgaaactt tcttttactt aatattttaa ttcctttttt
     3061 cgtttttcga gacagagttt ctctgtatag ccctgactgt cctggaactc actttttaga
     3121 ccaggctggc ctcgaactca gagatccacc tgcctctgca tcccgagtgc tgggattaaa
     3181 ggtgtgcacc accatgcctg gctgttaatg tttttaaaac tatgtttttc accttctaag
     3241 aaagatttga taagaagtgc attatttcct tatatatagt catatatagt cattatatag
     3301 atactaacac tttaaagtac attctacttc caaatgaaat gatgtcatat atttctcttt
     3361 acatttgctt ccataatgca gcatgacata tattaaattt tcaacatgta ataaataacc
     3421 tgatacccgg gttcttaaca gtagagtaat catgttctgt ttgtgactcc cgcagtttca
     3481 caattgattc cttcattgtt ccttatctga cttgttcctc tagcttgaat attgtgaagc
     3541 aaatataaag acataacaat gttgctacta gatgcctatt tttaaataaa gccatgccag
     3601 attaaaatga aatgatggac aaagatatgt tactaggata catgctctcc cttattttct
     3661 ggtcttctac agtctttctg ctttcctact cctcaatgtt ttctgaatat caggtgtggg
     3721 agtcatttat acatgtattc cttttaactg ggctccatac atctacattt ttttctgatt
     3781 ttccttagtt ttcgttgtct ttgttacaaa gagaactttt cacaatgaga ggtgaggact
     3841 acacttagat gtgggtataa ggacaaatat atagaatgaa cttaggaatt atgttaatga
     3901 atacagcaat ggttgtagat ttccctccaa aaattcataa cttcaccagc cctgaataaa
     3961 tagctaggct tcccatgtca catatgattt ccccttttga ttacatgtta agtctaattg
     4021 gagatctgtt gattactaca gagttatgtg aggtatctgt gcagccttag gattattatg
     4081 ccttgatagc atttgatgat atttgtaggc atcataactg tacatgacta ctaatcactt
     4141 ccttccttta gaagcttgca tggtatgttc tggtacatga atggg
//
