LOCUS       NM_183170                955 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus MPV17 mitochondrial membrane protein-like 2 (Mpv17l2),
            mRNA.
ACCESSION   NM_183170
VERSION     NM_183170.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 955)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 955)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            CAAA01070179.1.
            
            On Nov 17, 2006 this sequence version replaced NM_183170.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY013699.1, BC051227.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-202               CAAA01070179.1     7933-8134
            203-373             CAAA01070179.1     8316-8486
            374-450             CAAA01070179.1     9387-9463
            451-579             CAAA01070179.1     9617-9745
            580-955             CAAA01070179.1     9830-10205
FEATURES             Location/Qualifiers
     source          1..955
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 34.15 cM"
     gene            1..955
                     /gene="Mpv17l2"
                     /gene_synonym="Fksg24"
                     /note="MPV17 mitochondrial membrane protein-like 2"
                     /db_xref="GeneID:234384"
                     /db_xref="MGI:MGI:2681846"
     exon            1..202
                     /gene="Mpv17l2"
                     /gene_synonym="Fksg24"
                     /inference="alignment:Splign:2.1.0"
     CDS             16..618
                     /gene="Mpv17l2"
                     /gene_synonym="Fksg24"
                     /codon_start=1
                     /product="mpv17-like protein 2"
                     /protein_id="NP_898993.1"
                     /db_xref="CCDS:CCDS22380.1"
                     /db_xref="GeneID:234384"
                     /db_xref="MGI:MGI:2681846"
                     /translation="MALGGWRWARKALAAGRPLFQGRALLLTNTLGCGVLMAAGDGAR
                     QVWEVRARPGQRFSARRSASMFAVGCSMGPFLHFWYLWLDRLLPASGLRSLPSVMKKV
                     LVDQTVASPILGVWYFLGLGSLEGQTLEESCQELRAKFWDFYKADWCVWPAAQLVNFL
                     FIPSHFRVTYINGLTLGWDTYLSYLKYWVPEPLQTPGCAD"
     exon            203..373
                     /gene="Mpv17l2"
                     /gene_synonym="Fksg24"
                     /inference="alignment:Splign:2.1.0"
     exon            374..450
                     /gene="Mpv17l2"
                     /gene_synonym="Fksg24"
                     /inference="alignment:Splign:2.1.0"
     exon            451..579
                     /gene="Mpv17l2"
                     /gene_synonym="Fksg24"
                     /inference="alignment:Splign:2.1.0"
     exon            580..955
                     /gene="Mpv17l2"
                     /gene_synonym="Fksg24"
                     /inference="alignment:Splign:2.1.0"
     regulatory      934..939
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mpv17l2"
                     /gene_synonym="Fksg24"
                     /note="hexamer: ATTAAA"
     polyA_site      955
                     /gene="Mpv17l2"
                     /gene_synonym="Fksg24"
                     /note="major polyA site"
ORIGIN      
        1 gtgtctgtag cggcgatggc tctgggaggc tggcgctggg ctcgcaaggc gttggctgcg
       61 gggcgcccgc tgttccaggg ccgcgcgctg ctcctcacca acacactggg ctgcggcgtg
      121 ctcatggccg cgggcgatgg cgcgcgacag gtctgggaag tgcgcgcgcg gcctggacag
      181 agattcagcg cgcggcgctc agccagcatg ttcgccgtgg gctgcagcat gggccccttc
      241 ctacacttct ggtatctgtg gttggaccgc ctcctccccg cgtcgggcct acgaagcctc
      301 ccgagtgtga tgaagaaggt gctagtggat caaacggtgg catctcccat tctgggcgtc
      361 tggtacttcc tgggccttgg cagcctggag ggtcagacac tagaggagag ctgccaggag
      421 ctgcgggcca aattctggga cttctacaag gccgactggt gtgtgtggcc agctgcccag
      481 ctagtgaact tcctcttcat cccttctcat ttccgagtca cctatatcaa tgggctgaca
      541 ctgggctggg acacatacct gtcctatctg aagtactggg tccctgaacc ccttcagact
      601 ccgggctgtg cagactgaaa ctgaagcctg gcagatgagt tggccgatgg atacactccc
      661 acaggagatt accgaagctg gtcaaaaagc tctgggccat gtccaaaacc caggctgact
      721 gcccctggac cagcagtccc ttgagtccac cagagactgt tcccatgtag aacagacgcc
      781 agcacaggct gtccgccctc cccccaaccc ctcccggttt tccagtggga ccatgaagcc
      841 ctctgtctgc ctggacaccc tccacagcct tgaagtgggg tctggtttgg cctcagaaaa
      901 cttgatgcaa ggctgggcag ggtgcggaaa ttcattaaat tctctttaat gtcaa
//
