LOCUS       NM_001205011             694 bp    mRNA    linear   ROD 22-JAN-2024
DEFINITION  Mus musculus mucosal pentraxin 2 (Mptx2), mRNA.
ACCESSION   NM_001205011 XM_003084463 XM_003086171
VERSION     NM_001205011.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 694)
  AUTHORS   Yan,W., Chen,S., Wang,Y., You,Y., Lu,Y., Wang,W., Wu,B., Du,J.,
            Peng,S., Cai,W. and Xiao,Y.
  TITLE     Loss of Mptx2 alters bacteria composition and intestinal
            homeostasis potentially by impairing autophagy
  JOURNAL   Commun Biol 7 (1), 94 (2024)
   PUBMED   38218976
  REMARK    GeneRIF: Loss of Mptx2 alters bacteria composition and intestinal
            homeostasis potentially by impairing autophagy.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 694)
  AUTHORS   Balasubramanian,I., Bandyopadhyay,S., Flores,J., Bianchi-Smak,J.,
            Lin,X., Liu,H., Sun,S., Golovchenko,N.B., Liu,Y., Wang,D.,
            Patel,R., Joseph,I., Suntornsaratoon,P., Vargas,J., Green,P.H.,
            Bhagat,G., Lagana,S.M., Ying,W., Zhang,Y., Wang,Z., Li,W.V.,
            Singh,S., Zhou,Z., Kollias,G., Farr,L.A., Moonah,S.N., Yu,S.,
            Wei,Z., Bonder,E.M., Zhang,L., Kiela,P.R., Edelblum,K.L.,
            Ferraris,R., Liu,T.C. and Gao,N.
  TITLE     Infection and inflammation stimulate expansion of a CD74+ Paneth
            cell subset to regulate disease progression
  JOURNAL   EMBO J 42 (21), e113975 (2023)
   PUBMED   37718683
REFERENCE   3  (bases 1 to 694)
  AUTHORS   Zhu,J., Wang,Y., Wang,W., Wu,B., Lu,Y., Du,J., Cai,W. and Xiao,Y.
  TITLE     Mptx2 defends against peritoneal infection by methicillin-resistant
            staphylococcus aureus
  JOURNAL   Int Immunopharmacol 108, 108856 (2022)
   PUBMED   35609377
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC087781.17.
            
            On Oct 25, 2011 this sequence version replaced NM_001205011.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189685.299992.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-98                AC087781.17        73982-74079
            99-694              AC087781.17        76682-77277
FEATURES             Location/Qualifiers
     source          1..694
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 80.33 cM"
     gene            1..694
                     /gene="Mptx2"
                     /gene_synonym="Gm11062"
                     /note="mucosal pentraxin 2"
                     /db_xref="GeneID:100504232"
                     /db_xref="MGI:MGI:3779286"
     exon            1..98
                     /gene="Mptx2"
                     /gene_synonym="Gm11062"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..694
                     /gene="Mptx2"
                     /gene_synonym="Gm11062"
                     /codon_start=1
                     /product="Mucosal pentraxin precursor"
                     /protein_id="NP_001191940.1"
                     /db_xref="CCDS:CCDS56658.1"
                     /db_xref="GeneID:100504232"
                     /db_xref="MGI:MGI:3779286"
                     /translation="MEKLIVGILFLSVLSGSVAQTDMKGKAFIFPQESSTAYVSLIPK
                     VRKSLQNFTLCIKAFTDLTRPYSIFSYSTRTKDNEILLFVEKRGEYMLYVGNSGVSFK
                     APTNLPDPVRICVNWESGSGIAEFWLNGKAFGRKGLKKGYVVGGDAKIILGQEQDSFG
                     GKFDVKQSFVGEIWDVSLWNYVVPIKEVHDSCNNGNIINWQALIHEDRGYVVTKPKLW
                     T"
     exon            99..694
                     /gene="Mptx2"
                     /gene_synonym="Gm11062"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctcccacta ctggaattgt ccaagaagag cacaatggag aagcttattg tgggcatcct
       61 gtttctctct gttctttcag gaagtgtagc acaaacagac atgaagggaa aggcatttat
      121 tttccctcaa gaatcatcca ctgcctatgt gtccctgata ccgaaggtga ggaagtcact
      181 gcagaacttc actctgtgta taaaggcctt cacagacctg actcgccctt atagcatctt
      241 ctcctacagc acaagaacta aggacaatga gattcttctc tttgtggaaa agagaggaga
      301 atatatgctc tatgttggga attcgggagt cagtttcaaa gcacccacaa atcttcctga
      361 tccagtccgt atctgtgtga actgggagtc tggctctggg attgcagaat tctggctgaa
      421 tggaaaggca tttgggagaa aaggcttgaa gaagggatac gtggtggggg gtgatgcaaa
      481 gatcattcta ggacaagaac aggattcctt tgggggaaaa tttgatgtaa aacaatcctt
      541 tgttggggaa atatgggatg tttccttgtg gaactatgtg gtccccataa aagaggtgca
      601 tgacagctgt aacaatggca atattataaa ctggcaagct cttattcatg aagacagggg
      661 ctatgtggtg actaagccca aactgtggac ttaa
//
