LOCUS       NM_001357518            2503 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus metallophosphoesterase 1 (Mppe1), transcript variant
            2, mRNA.
ACCESSION   NM_001357518 XM_006525890
VERSION     NM_001357518.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2503)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC140336.2 and BM898884.1.
            
            On Nov 4, 2017 this sequence version replaced XM_006525890.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC086456.1, ERR2680377.51348.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164143 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-449               AC140336.2         2552-3000
            450-533             AC140336.2         4335-4418
            534-916             AC140336.2         10650-11032
            917-1025            AC140336.2         14673-14781
            1026-1129           AC140336.2         18604-18707
            1130-1204           AC140336.2         19378-19452
            1205-1313           AC140336.2         20261-20369
            1314-1385           AC140336.2         20507-20578
            1386-1508           AC140336.2         20663-20785
            1509-1649           AC140336.2         21459-21599
            1650-2473           AC140336.2         22498-23321
            2474-2503           BM898884.1         1-30                c
FEATURES             Location/Qualifiers
     source          1..2503
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 39.9 cM"
     gene            1..2503
                     /gene="Mppe1"
                     /gene_synonym="Pgap5"
                     /note="metallophosphoesterase 1"
                     /db_xref="GeneID:225651"
                     /db_xref="MGI:MGI:2661311"
     exon            1..449
                     /gene="Mppe1"
                     /gene_synonym="Pgap5"
                     /inference="alignment:Splign:2.1.0"
     exon            450..533
                     /gene="Mppe1"
                     /gene_synonym="Pgap5"
                     /inference="alignment:Splign:2.1.0"
     exon            534..916
                     /gene="Mppe1"
                     /gene_synonym="Pgap5"
                     /inference="alignment:Splign:2.1.0"
     CDS             642..1832
                     /gene="Mppe1"
                     /gene_synonym="Pgap5"
                     /EC_number="3.1.-.-"
                     /note="isoform 2 is encoded by transcript variant 2;
                     post-GPI attachment to proteins factor 5"
                     /codon_start=1
                     /product="metallophosphoesterase 1 isoform 2"
                     /protein_id="NP_001344447.1"
                     /db_xref="GeneID:225651"
                     /db_xref="MGI:MGI:2661311"
                     /translation="MALVRWGLKRQNFHPLRRRRRALLLKLTVVIISVLLFCEYFIYY
                     LVLFRCHWPEVKTLAHGGRQEPVLKAMFLADTHLLGEIRGHWLDKLRREWQMERAFQT
                     ALWLLQPEVVFILGDIFDEGKWSSDQAWADDVQRFQRMFRHDSHVQLKVVIGNHDVGF
                     HYQMSKYRIKRFEKVFGSERLLSLKGVNFVMVNSVAMEGDGCIICSEEEAELREISRK
                     LNCSQEVPGSSQCDREPEPRLPLSAPVLLQHYPLYRASDANCSGEDAAPPEERNVPFE
                     EKYDVLSREASQKLLWWLRPRLVLSGHTHSACEVLHPGGAPEVSVPSFSWRNRNNPSF
                     IMGSLTSRDYALSKCYLPFEDTVLTMYGAAAGFLMILILVHFEHLPSPFLCGWKLCRL
                     HMRR"
     exon            917..1025
                     /gene="Mppe1"
                     /gene_synonym="Pgap5"
                     /inference="alignment:Splign:2.1.0"
     exon            1026..1129
                     /gene="Mppe1"
                     /gene_synonym="Pgap5"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..1204
                     /gene="Mppe1"
                     /gene_synonym="Pgap5"
                     /inference="alignment:Splign:2.1.0"
     exon            1205..1313
                     /gene="Mppe1"
                     /gene_synonym="Pgap5"
                     /inference="alignment:Splign:2.1.0"
     exon            1314..1385
                     /gene="Mppe1"
                     /gene_synonym="Pgap5"
                     /inference="alignment:Splign:2.1.0"
     exon            1386..1508
                     /gene="Mppe1"
                     /gene_synonym="Pgap5"
                     /inference="alignment:Splign:2.1.0"
     exon            1509..1649
                     /gene="Mppe1"
                     /gene_synonym="Pgap5"
                     /inference="alignment:Splign:2.1.0"
     exon            1650..2486
                     /gene="Mppe1"
                     /gene_synonym="Pgap5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2451..2456
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mppe1"
                     /gene_synonym="Pgap5"
                     /note="hexamer: AATAAT"
     polyA_site      2486
                     /gene="Mppe1"
                     /gene_synonym="Pgap5"
                     /note="major polyA site"
ORIGIN      
        1 ccccacaata agcctctgac cggctcattg acacaagacg ccttccttga gtatttttcc
       61 aaaacgacac cttgccaggt tcgggagatg acaaaagaca taaaacgcag cagtggcccg
      121 tggttgccgg ccggaaggac tctcgcggct tcctgagctg attcccgaga agctgccacg
      181 gcggctgaga ctttggccgc agggcgcggg gcggcgggag ccacagtggc ggctgtgcag
      241 cgcgcaggtc ccgcggtccc caggcgcgcg gttcggtccc caacgagccg gtcctctatt
      301 cgagcatcac ccaccgactc ctggcggctc cttcctgcca ccgctcggtg tagctgcgac
      361 ttcctggagg cgccgccgtc ccaggcccgg ggaagggcgc aggcggtccc cggaggatgg
      421 ccccggcgaa ccggccgccg cagccctgca taactgtggt ctgattttgg aatgcagata
      481 ccaacctgga gtctgggcac ccaactcagc ctaggagtag cattctttaa aaggtacagc
      541 tcgggactgg gccccgtctc cactcctacc ttcctcaggc ttccatggtg ggttcttgat
      601 ggacttggtt ctcttctgct ggcaactcct gggcaggaga catggctctg gtcagatggg
      661 ggctgaaaag acagaacttc catccgttga ggaggaggag gagagcgttg ctgttgaaac
      721 tcacagttgt cattatctct gtgcttctgt tttgtgaata tttcatctat tacctggtcc
      781 tctttcggtg ccattggcct gaggtgaaga ctttagccca tggaggcagg caggagcctg
      841 tactgaaagc catgtttctg gctgacactc acttacttgg ggagataaga ggccattggc
      901 tggacaaatt acgaagggag tggcaaatgg agagagcttt tcagacagct ctgtggttgc
      961 tgcaaccgga agtcgtcttc attttgggag acatctttga tgaagggaag tggagctccg
     1021 atcaggcctg ggcagacgat gtgcagagat ttcagaggat gttcagacat gacagccatg
     1081 tgcagctgaa ggtggtcatt ggcaatcatg acgttggctt ccactatcag atgagtaaat
     1141 acagaataaa gcgatttgag aaagtgttcg gctctgaaag actgctctct ctgaaaggag
     1201 ttaattttgt catggtcaac agcgttgcaa tggaagggga tggttgtatc atatgctctg
     1261 aagaggaagc tgaactcaga gagatctctc gtaaactgaa ttgctcccaa gaggtgccgg
     1321 gatccagtca gtgtgaccgt gagcccgagc cgaggctccc cttgtccgct ccagtgttgc
     1381 tgcagcacta cccgctctac cgggccagcg atgctaactg ttcaggtgaa gatgcggctc
     1441 ccccagagga aaggaacgtc ccctttgagg agaaatatga tgttctttct cgggaggcct
     1501 cacaaaagct gttgtggtgg ctccggcctc gcctggttct gagtggccac acacacagtg
     1561 cctgtgaggt gctccaccca ggaggagccc ctgaggtgag cgtcccatct ttcagttgga
     1621 ggaaccgaaa caacccaagt ttcatcatgg gcagcctgac atccagagat tacgctctgt
     1681 ccaagtgcta cctcccgttt gaggacacgg tgctgaccat gtacggtgca gcggctggct
     1741 tcctcatgat cctcatctta gttcactttg agcatctgcc ctcgcctttt ctgtgtggct
     1801 ggaaactgtg caggttgcac atgaggagat gaagagccgg tgactgttgt gtatggtgat
     1861 acgaatcaaa gccaaagacc tataggactt ccagcgaggg tcctgcaagt cccggaggag
     1921 agcaaatgct ggttgttcct atgtacatgg tggggattct gaatcttcaa cgtgactacg
     1981 gaataaatgg ttgactgtac tgttctcatg ctataaaaat ggaacatgtt ctctgcaaca
     2041 aattcatctt ttcatttaat gaaacgtatg tataatcaaa ggttccatag gtatggaatg
     2101 taaatgtcat ggacactacc actcgcatgc atgacacaca gtcctttctt ccacaggaag
     2161 gacccagcag ctttggtgca cactcgaggc tatgtgtgct cctaaacatt ggggcttctc
     2221 tgtacttctg tgaagtggct ctcagtttct tgcagattat gaagctatat gctcaaaagt
     2281 acagattcaa tgagtaggac taaaggcttt tgtgtttctg tgctaatgca attggatttt
     2341 taggtacgtg taattttctt tccgggagac catgttatcg catctgaact caatgtctgc
     2401 tcatgactaa aacttcaaca tggatggttg aatttaagaa caaatgatgt aataattctg
     2461 tcagataaag catattcttt ttcttaaaaa aaaaaaaaaa aaa
//
