LOCUS       NM_023773               2954 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus M-phase phosphoprotein 8 (Mphosph8), transcript
            variant 1, mRNA.
ACCESSION   NM_023773
VERSION     NM_023773.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2954)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2954)
  AUTHORS   Zhang,H., Yang,T., Wu,H., Yi,W., Dai,C., Chen,X., Zhang,W. and
            Ye,Y.
  TITLE     MPP8 Governs the Activity of the LIF/STAT3 Pathway and Plays a
            Crucial Role in the Differentiation of Mouse Embryonic Stem Cells
  JOURNAL   Cells 12 (16), 2023 (2023)
   PUBMED   37626833
  REMARK    GeneRIF: MPP8 Governs the Activity of the LIF/STAT3 Pathway and
            Plays a Crucial Role in the Differentiation of Mouse Embryonic Stem
            Cells.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2954)
  AUTHORS   Hagelkruys,A., Horrer,M., Taubenschmid-Stowers,J., Kavirayani,A.,
            Novatchkova,M., Orthofer,M., Pai,T.P., Cikes,D., Zhuk,S.,
            Balmana,M., Esk,C., Koglgruber,R., Moeseneder,P., Lazovic,J.,
            Zopf,L.M., Cronin,S.J.F., Elling,U., Knoblich,J.A. and
            Penninger,J.M.
  TITLE     The HUSH complex controls brain architecture and protocadherin
            fidelity
  JOURNAL   Sci Adv 8 (44), eabo7247 (2022)
   PUBMED   36332029
REFERENCE   4  (bases 1 to 2954)
  AUTHORS   Gresakova,V., Novosadova,V., Prochazkova,M., Prochazka,J. and
            Sedlacek,R.
  TITLE     Dual role of Fam208a during zygotic cleavage and early embryonic
            development
  JOURNAL   Exp Cell Res 406 (2), 112723 (2021)
   PUBMED   34216590
REFERENCE   5  (bases 1 to 2954)
  AUTHORS   Gu,Z., Liu,Y., Zhang,Y., Cao,H., Lyu,J., Wang,X., Wylie,A.,
            Newkirk,S.J., Jones,A.E., Lee,M. Jr., Botten,G.A., Deng,M.,
            Dickerson,K.E., Zhang,C.C., An,W., Abrams,J.M. and Xu,J.
  TITLE     Silencing of LINE-1 retrotransposons is a selective dependency of
            myeloid leukemia
  JOURNAL   Nat Genet 53 (5), 672-682 (2021)
   PUBMED   33833453
REFERENCE   6  (bases 1 to 2954)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   7  (bases 1 to 2954)
  AUTHORS   Yoshikawa,T., Piao,Y., Zhong,J., Matoba,R., Carter,M.G., Wang,Y.,
            Goldberg,I. and Ko,M.S.
  TITLE     High-throughput screen for genes predominantly expressed in the ICM
            of mouse blastocysts by whole mount in situ hybridization
  JOURNAL   Gene Expr Patterns 6 (2), 213-224 (2006)
   PUBMED   16325481
REFERENCE   8  (bases 1 to 2954)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY111264.1, AK158773.1 and BU757804.1.
            
            On Mar 21, 2009 this sequence version replaced NM_023773.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB041598.2, AK158773.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-23                BY111264.1         2-24
            24-2907             AK158773.1         2-2885
            2908-2954           BU757804.1         1-47                c
FEATURES             Location/Qualifiers
     source          1..2954
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 28.37 cM"
     gene            1..2954
                     /gene="Mphosph8"
                     /gene_synonym="1500035L22Rik; 4930548G07Rik"
                     /note="M-phase phosphoprotein 8"
                     /db_xref="GeneID:75339"
                     /db_xref="MGI:MGI:1922589"
     exon            1..317
                     /gene="Mphosph8"
                     /gene_synonym="1500035L22Rik; 4930548G07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            318..473
                     /gene="Mphosph8"
                     /gene_synonym="1500035L22Rik; 4930548G07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            474..1322
                     /gene="Mphosph8"
                     /gene_synonym="1500035L22Rik; 4930548G07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1323..1419
                     /gene="Mphosph8"
                     /gene_synonym="1500035L22Rik; 4930548G07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1420..1674
                     /gene="Mphosph8"
                     /gene_synonym="1500035L22Rik; 4930548G07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1675..1800
                     /gene="Mphosph8"
                     /gene_synonym="1500035L22Rik; 4930548G07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1801..1889
                     /gene="Mphosph8"
                     /gene_synonym="1500035L22Rik; 4930548G07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1890..2030
                     /gene="Mphosph8"
                     /gene_synonym="1500035L22Rik; 4930548G07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2031..2117
                     /gene="Mphosph8"
                     /gene_synonym="1500035L22Rik; 4930548G07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2118..2272
                     /gene="Mphosph8"
                     /gene_synonym="1500035L22Rik; 4930548G07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2273..2427
                     /gene="Mphosph8"
                     /gene_synonym="1500035L22Rik; 4930548G07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2428..2555
                     /gene="Mphosph8"
                     /gene_synonym="1500035L22Rik; 4930548G07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2556..2639
                     /gene="Mphosph8"
                     /gene_synonym="1500035L22Rik; 4930548G07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2640..2939
                     /gene="Mphosph8"
                     /gene_synonym="1500035L22Rik; 4930548G07Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2917..2922
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mphosph8"
                     /gene_synonym="1500035L22Rik; 4930548G07Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2939
                     /gene="Mphosph8"
                     /gene_synonym="1500035L22Rik; 4930548G07Rik"
                     /note="major polyA site"
ORIGIN      
        1 gagtcacgcc gctggagcgg attagggcgg agcggcaggc gcgcggtgct gtcccgctgt
       61 gggtcgccgg cggtttttcg cgttggtttt gcactgcgtc tgtgatggcg gcggcggctg
      121 aggagggcat gagtgcggcc gctctagtta tgtcagttcc cgacagcatt ggccgttctc
      181 ccgagtccga aggagttgga gcaggggacg aagagaagga cgcagccacc aaaggaacgg
      241 tggccgttgg ggacagcgag gaggatgggg aggacgtttt cgaggtggag aggatcctgg
      301 acatgaagtg cgagggaggt aagaatcttt ataaagttcg atggaaagga tatacatctg
      361 aagatgatac ctgggagcct gaggttcatc tggaggactg taaggaagtt cttcttgaat
      421 tcaggaagaa acttgctgag aacaaagcta aagcagtcag gaaagatatt cagagactat
      481 ctttaaacaa tgacatattt gaggcagaca gtgatagcga ccagcaaagt gacacaaaag
      541 aagatatttc accaaggaag aaaaagaaaa aaataaagtg caaagaagag acaagtccag
      601 aagatctgag gaaaaaaagg acaaaaatgg gaaaactaaa agacaagttc aagacagagc
      661 tggagagcac ctctgaaata atcggtttcg atgtaaagac gaagaaaaga atttgggaag
      721 tcaaggaaga attaaaggac tccaaaaagc ccaaaaagga tgaaataaag gaaaccaagg
      781 aattaaagaa agctaataaa agggctgaag taagagattt aaagattaaa ataagagaag
      841 atgtcaaaga gaaccgaaaa acaaaaaaag agagatatat agaatctccg ctggagtctg
      901 aatcgcctaa tgattccctc attctagagg atgacagtga agactttatt tctgacaaca
      961 gagaagagaa tcagaatgtg agaagtgtaa gagataagac agcacaggag acagtgcaag
     1021 agggtatttt tgagaaacat ctggatgacc ttataagtat tgaagaggat gctggtaccc
     1081 gagttagaag gaagaagacg aagccaagaa agtttgagga accaaaagag atcaagaagc
     1141 ttgaaagcac gaatgccttt ttagaaagga gagcaatacc caaaaagcaa agaaaccaag
     1201 acaagggcat aagtaaccta gagttaaata agctaccatc acctgtgttt gcccaaaccc
     1261 tgaaaagttc cagactgagt ggggaagaga agagcctaaa gtcccctgac ttggcagaag
     1321 aggagaaaga gaaaaaaaat gaacccaaag gaaaatacca gaaaaggtat gatttggaca
     1381 aagaagaaaa agccagaaaa gagccaaagg tattaaaatc atttaaggaa atcagaaatg
     1441 catttgattt atttaaaaaa acaacagaag aaaaaaatga tgttcttgag aataattcaa
     1501 aaagagaaga aatatcactg gattctaaaa ttatgaatga taacaaaacc aaggacaagt
     1561 gttcacttaa agaaaaaaga aatactcgag atgagactga cacttgggca tacattgctg
     1621 cagaagggga tcaggaagtt tcagacagtg tatgccaaac agatgagacg tctgatggca
     1681 ggcaaccagt tttgagtttg ggtatggacc tgcagctgga gtggatgaaa ttagaagatt
     1741 ttcagaagca tctggatggg gaagatgagc cctttatcac aacaaacagg attccaaata
     1801 atttgttgag ggatgctgtg aaaaatggag attatattgc tgtgaaggtt gcactgaact
     1861 caaatgaaga atacaacttg gatcaagagg attctactgg gatgaccctg gtgatgttgg
     1921 ctgcagcagg cggtcaggac gacctcctca gactccttat caccaaaggt gcaaaagtga
     1981 atgggcgcca gaaaaacggg actacagccc tcattcatgc cgctgagaag aactttttaa
     2041 caactgtagc tattcttttg gaagctggag cttttgtgaa tgttcagcaa agcaatggtg
     2101 agactgcgct catgaaagca tgcaaaagag gaaattcgga cattgtccgc cttgtgattg
     2161 aatgtggagc tgactgcaac attttgtcaa agcaccaaaa tagtgcattg tactttgcaa
     2221 agcagtgtaa taatgtgctt gtatatgaac tgctgaagag ccacttggag acactttcca
     2281 gagttgcaga agaaacaatc agggattact ttgaatctcg ccttgctcta ctggaacctg
     2341 ttttcccaat agcatgccat cggctctgtg aggggccgga tttctcaaca gatttcaatt
     2401 acatgccccc tcagaacatg cctgaaggct ctggtgtcct cctctttatt ttccatgcaa
     2461 actttttggg caaagacgtt attgctcggc tttgtggacc atgcagtgta caagctgtgg
     2521 ttttaaatga taaatttcaa cttcctgttt ttctggacag tcactttgtt tattcattca
     2581 gtcctgttgc tggccccaat aagttgttta taaggttgac ggaagcaccc tttgccaagg
     2641 ttaagttgct aataggtgca tacagagtac agctgcagtg accacaaagg atggagaacc
     2701 ggcctctttt cagctggatt ccaaggacca tccctgtagc agtttggaat tctggtgcag
     2761 ctcaaatgtt cctacctagt tgtaaactta aaatttaagc ctgctgcctg ttcaggtttg
     2821 tctacatata tttgtgccat tggtcgaaaa cgttcaatgt tctgcttagt ttatttccac
     2881 aatgtggaac agtacgtgta agaaatattt aaggaaatta aaaacctttt gaattgaaaa
     2941 aaaaaaaaaa aaaa
//
