LOCUS       NM_021509               3083 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus monooxygenase, DBH-like 1 (Moxd1), mRNA.
ACCESSION   NM_021509
VERSION     NM_021509.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3083)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3083)
  AUTHORS   Wan,Y., Rogers,M.B. and Szabo-Rogers,H.L.
  TITLE     A six-gene expression toolbox for the glands, epithelium and
            chondrocytes in the mouse nasal cavity
  JOURNAL   Gene Expr Patterns 27, 46-55 (2018)
   PUBMED   29122676
REFERENCE   3  (bases 1 to 3083)
  AUTHORS   Rutledge,E.A., Benazet,J.D. and McMahon,A.P.
  TITLE     Cellular heterogeneity in the ureteric progenitor niche and
            distinct profiles of branching morphogenesis in organ development
  JOURNAL   Development 144 (17), 3177-3188 (2017)
   PUBMED   28705898
REFERENCE   4  (bases 1 to 3083)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   5  (bases 1 to 3083)
  AUTHORS   Narayanan,R., Pirouz,M., Kerimoglu,C., Pham,L., Wagener,R.J.,
            Kiszka,K.A., Rosenbusch,J., Seong,R.H., Kessel,M., Fischer,A.,
            Stoykova,A., Staiger,J.F. and Tuoc,T.
  TITLE     Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and
            Chromatin State Changes in Forebrain Development
  JOURNAL   Cell Rep 13 (9), 1842-1854 (2015)
   PUBMED   26655900
REFERENCE   6  (bases 1 to 3083)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   7  (bases 1 to 3083)
  AUTHORS   Miller,J.A., Nathanson,J., Franjic,D., Shim,S., Dalley,R.A.,
            Shapouri,S., Smith,K.A., Sunkin,S.M., Bernard,A., Bennett,J.L.,
            Lee,C.K., Hawrylycz,M.J., Jones,A.R., Amaral,D.G., Sestan,N.,
            Gage,F.H. and Lein,E.S.
  TITLE     Conserved molecular signatures of neurogenesis in the hippocampal
            subgranular zone of rodents and primates
  JOURNAL   Development 140 (22), 4633-4644 (2013)
   PUBMED   24154525
REFERENCE   8  (bases 1 to 3083)
  AUTHORS   Tamplin,O.J., Cox,B.J. and Rossant,J.
  TITLE     Integrated microarray and ChIP analysis identifies multiple Foxa2
            dependent target genes in the notochord
  JOURNAL   Dev Biol 360 (2), 415-425 (2011)
   PUBMED   22008794
REFERENCE   9  (bases 1 to 3083)
  AUTHORS   Hoerder-Suabedissen,A., Wang,W.Z., Lee,S., Davies,K.E.,
            Goffinet,A.M., Rakic,S., Parnavelas,J., Reim,K., Nicolic,M.,
            Paulsen,O. and Molnar,Z.
  TITLE     Novel markers reveal subpopulations of subplate neurons in the
            murine cerebral cortex
  JOURNAL   Cereb Cortex 19 (8), 1738-1750 (2009)
   PUBMED   19008461
REFERENCE   10 (bases 1 to 3083)
  AUTHORS   Xin,X., Mains,R.E. and Eipper,B.A.
  TITLE     Monooxygenase X, a member of the copper-dependent monooxygenase
            family localized to the endoplasmic reticulum
  JOURNAL   J Biol Chem 279 (46), 48159-48167 (2004)
   PUBMED   15337741
  REMARK    GeneRIF: Based on its sequence and localization, MOX (monooxygenase
            X) is predicted to hydroxylate a hydrophobic substrate in the
            endoplasmic reticulum.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC125010.6.
            
            On Apr 29, 2007 this sequence version replaced NM_021509.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK014340.1, BC057652.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-351               AC125010.6         85127-85477         c
            352-498             AC125010.6         64608-64754         c
            499-666             AC125010.6         56364-56531         c
            667-750             AC125010.6         55979-56062         c
            751-930             AC125010.6         29449-29628         c
            931-1033            AC125010.6         29049-29151         c
            1034-1200           AC125010.6         27410-27576         c
            1201-1392           AC125010.6         26240-26431         c
            1393-1452           AC125010.6         24179-24238         c
            1453-1595           AC125010.6         21845-21987         c
            1596-1764           AC125010.6         8670-8838           c
            1765-3083           AC125010.6         6211-7529           c
FEATURES             Location/Qualifiers
     source          1..3083
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 11.48 cM"
     gene            1..3083
                     /gene="Moxd1"
                     /gene_synonym="3230402N08Rik; MNCb-5203"
                     /note="monooxygenase, DBH-like 1"
                     /db_xref="GeneID:59012"
                     /db_xref="MGI:MGI:1921582"
     exon            1..351
                     /gene="Moxd1"
                     /gene_synonym="3230402N08Rik; MNCb-5203"
                     /inference="alignment:Splign:2.1.0"
     CDS             88..1929
                     /gene="Moxd1"
                     /gene_synonym="3230402N08Rik; MNCb-5203"
                     /note="DBH-like monooxygenase protein 1; monooxygenase X;
                     DBH-related protein"
                     /codon_start=1
                     /product="DBH-like monooxygenase protein 1 precursor"
                     /protein_id="NP_067484.2"
                     /db_xref="CCDS:CCDS23750.1"
                     /db_xref="GeneID:59012"
                     /db_xref="MGI:MGI:1921582"
                     /translation="MCGWPLLVLWALLPATAAGSPGRSYPHRVVLDPEGKYWLHWGRQ
                     GERLAFRLEVRTNGYVGFGFSPTGSMAAADIVVGGVAHGRPYLQDYFTNADRELEKDA
                     QQDYHLDYAMENSTHTVIEFSRELHTCDVNDKSLTDSTVRVIWAYHHDDPGESGPKYH
                     DLNRGTRSLRLLNPEKANVVSTVLPYFDLVNQNVPIPNKGTTYWCQMFKIPTFQEKHH
                     VIKVEPIIERGHENLVHHILVYQCSSNFNDSVLDFGHECYHPNMPDAFLTCETVILAW
                     GIGGEGFTYPPHVGLSLGMPLDPRYVLLEVHYDNPARRKGLIDSSGLRVFHTTDIRRY
                     DAGVIEAGLWVSLFHTIPPGMPEFHSEGHCTLECLEEALGAEKPSGIHVFAVLLHAHL
                     AGKGIRLRHFRKGEEMKLLAYDDDYDFNFQEFQYLREEQTILPGDNLITECRYNTKDR
                     AVMTWGGLSTRNEMCLSYLLYYPRVNLTRCSSIPDIMEQLQFIGVKEIYRPVTTWPFI
                     IKSPKQYRNLSFMDAMNKFKWTKKEGLSFNKLVLSLPVNVRCSKTDNAEWSIQGMTAI
                     PPDIKRPYEAEPLVCEKAASPPLHGIFSLRLLTCALLLGSMLSSQGL"
     exon            352..498
                     /gene="Moxd1"
                     /gene_synonym="3230402N08Rik; MNCb-5203"
                     /inference="alignment:Splign:2.1.0"
     exon            499..666
                     /gene="Moxd1"
                     /gene_synonym="3230402N08Rik; MNCb-5203"
                     /inference="alignment:Splign:2.1.0"
     exon            667..750
                     /gene="Moxd1"
                     /gene_synonym="3230402N08Rik; MNCb-5203"
                     /inference="alignment:Splign:2.1.0"
     exon            751..930
                     /gene="Moxd1"
                     /gene_synonym="3230402N08Rik; MNCb-5203"
                     /inference="alignment:Splign:2.1.0"
     exon            931..1033
                     /gene="Moxd1"
                     /gene_synonym="3230402N08Rik; MNCb-5203"
                     /inference="alignment:Splign:2.1.0"
     exon            1034..1200
                     /gene="Moxd1"
                     /gene_synonym="3230402N08Rik; MNCb-5203"
                     /inference="alignment:Splign:2.1.0"
     exon            1201..1392
                     /gene="Moxd1"
                     /gene_synonym="3230402N08Rik; MNCb-5203"
                     /inference="alignment:Splign:2.1.0"
     exon            1393..1452
                     /gene="Moxd1"
                     /gene_synonym="3230402N08Rik; MNCb-5203"
                     /inference="alignment:Splign:2.1.0"
     exon            1453..1595
                     /gene="Moxd1"
                     /gene_synonym="3230402N08Rik; MNCb-5203"
                     /inference="alignment:Splign:2.1.0"
     exon            1596..1764
                     /gene="Moxd1"
                     /gene_synonym="3230402N08Rik; MNCb-5203"
                     /inference="alignment:Splign:2.1.0"
     exon            1765..3083
                     /gene="Moxd1"
                     /gene_synonym="3230402N08Rik; MNCb-5203"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2980..2985
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Moxd1"
                     /gene_synonym="3230402N08Rik; MNCb-5203"
                     /note="hexamer: AATAAA"
     polyA_site      3003
                     /gene="Moxd1"
                     /gene_synonym="3230402N08Rik; MNCb-5203"
ORIGIN      
        1 gcggccagcc ccggggcggt cccaagttgg gctccctggt cttcgccccc cagtggctgc
       61 agcccaggtg cggcgcggga caggaggatg tgcggctggc cactgcttgt gctgtgggcg
      121 ctgctccccg cgacggctgc gggaagcccg ggccgctcgt acccgcaccg cgtggtcctc
      181 gatcccgaag gcaagtactg gctgcactgg ggccggcagg gcgagaggct ggccttccgt
      241 ctggaggtac gcacgaacgg ctacgtgggc ttcggcttct cgcccaccgg gagcatggcc
      301 gcggcagaca tcgtggtagg cggagtggcc cacgggcggc cctacctcca ggactatttc
      361 acaaacgcag acagagagtt ggaaaaagat gcccagcaag attaccacct agattacgcc
      421 atggagaaca gcacacacac agtgatcgag tttagcaggg agctgcacac gtgcgatgtc
      481 aatgacaaga gtctcacgga tagcaccgtg agagttatct gggcctacca ccatgacgat
      541 cccggagaat ctggtcccaa gtaccatgac ttaaataggg gcacaaggag tctacggtta
      601 ctgaatcctg agaaagccaa tgtggtgtct acagtcttac cgtactttga tctggtaaat
      661 caaaacgttc ccattccaaa caaaggcaca acatactggt gccaaatgtt taagattcct
      721 acattccaag aaaaacatca tgtgataaag gtggagccaa taatagagag aggccatgag
      781 aacctggtcc atcacatcct ggtctatcaa tgcagcagca actttaatga cagcgttctg
      841 gactttggcc atgagtgcta tcacccgaac atgcccgatg ccttcctcac ctgcgaaact
      901 gtgattctcg cctggggcat tggtggggag ggctttacct atccacctca cgttggctta
      961 tccctcggca tgccactgga tcctcgttat gtgcttttag aggtccacta cgataatccc
     1021 gcacggagga aaggcttaat agacagttcg gggctgaggg ttttccatac tacagatata
     1081 aggagatatg acgcaggggt gattgaggct ggcctctggg tgagcctctt ccacacaatt
     1141 cccccaggga tgcccgagtt ccattctgag ggtcactgca ctctggagtg cctagaggag
     1201 gccctgggag ctgagaaacc aagtggaatc cacgtgtttg cggtccttct ccatgctcac
     1261 ctggcaggca aaggcatcag gctgcgtcat tttcgaaaag gagaggaaat gaagttgctg
     1321 gcttatgatg acgattatga ctttaatttc caggagtttc agtatctgag ggaagaacaa
     1381 acaatcttac caggtgataa cctgatcact gaatgccggt ataacaccaa ggaccgagct
     1441 gtgatgactt ggggaggact aagcaccagg aatgaaatgt gtctctcata ccttctttat
     1501 tatccaagag ttaacctgac ccggtgctcc agcatcccag acatcatgga acagctgcag
     1561 ttcatcggcg tgaaggagat ctacagacct gtcacgacat ggcctttcat tatcaaaagc
     1621 cctaagcagt acagaaacct ttctttcatg gatgcaatga acaagttcaa atggacaaaa
     1681 aaggaagggc tgtccttcaa caagctcgtt cttagcctgc ctgtgaatgt gagatgttct
     1741 aagacagaca acgcagagtg gtcgattcaa ggcatgacag caatacctcc tgatatcaaa
     1801 aggccttatg aagcagaacc tctggtgtgc gagaaagcag cttccccacc tctacacggc
     1861 attttctccc tccgcttgct cacgtgcgct ctgcttcttg gaagtatgct gagcagccag
     1921 ggcttgtgac ttctgtcata ctcgagtctg gaatatgtga ctgtccctta aagtcaggtt
     1981 aaagaccatg tttatgtgag gcctggagag atgggtgggt acgaagagcc tggacactta
     2041 aatttctgca cacacaagtt ctttctgttt tccttcccag gctacctaag ccatgtcact
     2101 gtggttctct gggtttctcg accaaagttg atgttccgtg tatatgatta gtagaataaa
     2161 aatggacctg gtttatccac ttagcaagcc agcacatcaa gtggaaagca aagagtcttt
     2221 aatttttcag aattccatgt gatttcaaca tgacactcaa catccttctc acaaacatgc
     2281 tgaccttaat aacactagtg gacttactct ccgatcccat ttgctcttca tcctttctgg
     2341 gtgtaactcg ccagggtgag catagccctc tcttcgacag gtcccagtcc ctgtggtttc
     2401 tctgatttta ctcatggtcc tctgacctca gtgtttatct ctgcatcttt ggcttcctcc
     2461 atccaccaag tctgttgata cccaagccca catcaaagta tttcccagtc tttctagcac
     2521 tgtccagccg aatgtgtttc ttactctaca actctcttaa agaagagaga tgtgagtaag
     2581 tgtggggatg atgggggctg attgttaact ggggaagaaa atggagagca gtgaagggtt
     2641 ctagatgggg tgagatcccc aagacaggag gcagggccac agggtctgta aggttcctca
     2701 ccactcagtg ctaccctctg ggtcgatctg agtcccatgt cctataacag attcattttt
     2761 atattagtta ataaactgac ttccaataca aaactgccac caactgaagg tcttattctt
     2821 ttggttctct ttgtattatc tgcctaaatc ttgttttatg tcctatcttc atccattaag
     2881 ctgaatgtct ggatcaaatt cacaagctta aaggaataaa ggttttatat ggtgtcttat
     2941 gtgattcatg agagaatcaa gttgttgtgt actgatgtca ataaaatcag ccgagaaact
     3001 gtatttttcc actttaagcc ctttctgtct tacaaatatc atctatattg tcatttaaat
     3061 aaatattctg ctttagagtc ttc
//
