LOCUS       NM_001163440            3571 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus Mov10 RISC complex RNA helicase (Mov10), transcript
            variant 1, mRNA.
ACCESSION   NM_001163440
VERSION     NM_001163440.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3571)
  AUTHORS   Guan,Y., Gao,H., Leu,N.A., Vourekas,A., Alexiou,P., Maragkakis,M.,
            Kang,Z., Mourelatos,Z., Liang,G. and Wang,P.J.
  TITLE     The MOV10 RNA helicase is a dosage-dependent host restriction
            factor for LINE1 retrotransposition in mice
  JOURNAL   PLoS Genet 19 (5), e1010566 (2023)
   PUBMED   37126510
  REMARK    GeneRIF: The MOV10 RNA helicase is a dosage-dependent host
            restriction factor for LINE1 retrotransposition in mice.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3571)
  AUTHORS   Qian,B., Li,Y., Yan,R., Han,S., Bu,Z., Gong,J., Zheng,B., Yuan,Z.,
            Ren,S., He,Q., Zhang,J., Xu,C., Wang,R., Sun,Z., Lin,M., Zhou,J.
            and Ye,L.
  TITLE     RNA binding protein RBM46 regulates mitotic-to-meiotic transition
            in spermatogenesis
  JOURNAL   Sci Adv 8 (34), eabq2945 (2022)
   PUBMED   36001654
REFERENCE   3  (bases 1 to 3571)
  AUTHORS   Nawaz,A., Shilikbay,T., Skariah,G. and Ceman,S.
  TITLE     Unwinding the roles of RNA helicase MOV10
  JOURNAL   Wiley Interdiscip Rev RNA 13 (2), e1682 (2022)
   PUBMED   34327836
  REMARK    GeneRIF: Unwinding the roles of RNA helicase MOV10.
            Review article
REFERENCE   4  (bases 1 to 3571)
  AUTHORS   Yang,X., Xiang,Z., Sun,Z., Ji,F., Ren,K. and Pan,D.
  TITLE     Host MOV10 is induced to restrict herpes simplex virus 1 lytic
            infection by promoting type I interferon response
  JOURNAL   PLoS Pathog 18 (2), e1010301 (2022)
   PUBMED   35157734
  REMARK    GeneRIF: Host MOV10 is induced to restrict herpes simplex virus 1
            lytic infection by promoting type I interferon response.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3571)
  AUTHORS   Lannom,M.C., Nielsen,J., Nawaz,A., Shilikbay,T. and Ceman,S.
  TITLE     FMRP and MOV10 regulate Dicer1 expression and dendrite development
  JOURNAL   PLoS One 16 (11), e0260005 (2021)
   PUBMED   34847178
  REMARK    GeneRIF: FMRP and MOV10 regulate Dicer1 expression and dendrite
            development.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3571)
  AUTHORS   Mooslehner,K., Muller,U., Karls,U., Hamann,L. and Harbers,K.
  TITLE     Structure and expression of a gene encoding a putative GTP-binding
            protein identified by provirus integration in a transgenic mouse
            strain
  JOURNAL   Mol Cell Biol 11 (2), 886-893 (1991)
   PUBMED   1899287
REFERENCE   7  (bases 1 to 3571)
  AUTHORS   Munke,M., Harbers,K., Jaenisch,R. and Francke,U.
  TITLE     Chromosomal mapping of four different integration sites of Moloney
            murine leukemia virus including the locus for alpha 1(I) collagen
            in mouse
  JOURNAL   Cytogenet Cell Genet 43 (3-4), 140-149 (1986)
   PUBMED   3467899
REFERENCE   8  (bases 1 to 3571)
  AUTHORS   Jahner,D. and Jaenisch,R.
  TITLE     Chromosomal position and specific demethylation in enhancer
            sequences of germ line-transmitted retroviral genomes during mouse
            development
  JOURNAL   Mol Cell Biol 5 (9), 2212-2220 (1985)
   PUBMED   3837187
REFERENCE   9  (bases 1 to 3571)
  AUTHORS   Schnieke,A., Stuhlmann,H., Harbers,K., Chumakov,I. and Jaenisch,R.
  TITLE     Endogenous Moloney leukemia virus in nonviremic Mov substrains of
            mice carries defects in the proviral genome
  JOURNAL   J Virol 45 (2), 505-513 (1983)
   PUBMED   6834466
REFERENCE   10 (bases 1 to 3571)
  AUTHORS   Harbers,K., Schnieke,A., Stuhlmann,H. and Jaenisch,R.
  TITLE     Infectivity and structure of molecular clones obtained from two
            genetically transmitted Moloney leukemia proviral genomes
  JOURNAL   Nucleic Acids Res 10 (8), 2521-2537 (1982)
   PUBMED   6281733
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC171110.2.
            
            On Aug 8, 2022 this sequence version replaced NM_001163440.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13422600.1741429.1, AK159295.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-190               AC171110.2         76883-77072
            191-376             AC171110.2         77308-77493
            377-580             AC171110.2         90322-90525
            581-816             AC171110.2         90716-90951
            817-1078            AC171110.2         91037-91298
            1079-1213           AC171110.2         92502-92636
            1214-1382           AC171110.2         92835-93003
            1383-1537           AC171110.2         93877-94031
            1538-1714           AC171110.2         94296-94472
            1715-1862           AC171110.2         94595-94742
            1863-2021           AC171110.2         94996-95154
            2022-2125           AC171110.2         95380-95483
            2126-2223           AC171110.2         95634-95731
            2224-2440           AC171110.2         95821-96037
            2441-2558           AC171110.2         98037-98154
            2559-2750           AC171110.2         98268-98459
            2751-2825           AC171110.2         98588-98662
            2826-2951           AC171110.2         99444-99569
            2952-3040           AC171110.2         99647-99735
            3041-3162           AC171110.2         99983-100104
            3163-3571           AC171110.2         100189-100597
FEATURES             Location/Qualifiers
     source          1..3571
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 45.87 cM"
     gene            1..3571
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /note="Mov10 RISC complex RNA helicase"
                     /db_xref="GeneID:17454"
                     /db_xref="MGI:MGI:97054"
     exon            1..190
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /inference="alignment:Splign:2.1.0"
     exon            191..376
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /inference="alignment:Splign:2.1.0"
     exon            377..580
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /inference="alignment:Splign:2.1.0"
     exon            581..816
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /inference="alignment:Splign:2.1.0"
     exon            817..1078
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /inference="alignment:Splign:2.1.0"
     exon            1079..1213
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /inference="alignment:Splign:2.1.0"
     exon            1214..1382
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /inference="alignment:Splign:2.1.0"
     exon            1383..1537
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /inference="alignment:Splign:2.1.0"
     exon            1538..1714
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /inference="alignment:Splign:2.1.0"
     exon            1715..1862
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /inference="alignment:Splign:2.1.0"
     exon            1863..2021
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /inference="alignment:Splign:2.1.0"
     exon            2022..2125
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /inference="alignment:Splign:2.1.0"
     exon            2126..2223
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /inference="alignment:Splign:2.1.0"
     exon            2224..2440
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /inference="alignment:Splign:2.1.0"
     exon            2441..2558
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /inference="alignment:Splign:2.1.0"
     exon            2559..2750
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /inference="alignment:Splign:2.1.0"
     exon            2751..2825
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /inference="alignment:Splign:2.1.0"
     exon            2826..2951
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /inference="alignment:Splign:2.1.0"
     exon            2952..3040
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /inference="alignment:Splign:2.1.0"
     exon            3041..3162
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /inference="alignment:Splign:2.1.0"
     exon            3163..3571
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3548..3553
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /note="hexamer: AACAAA"
     polyA_site      3571
                     /gene="Mov10"
                     /gene_synonym="Mov-10"
                     /note="major polyA site"
ORIGIN      
        1 agtccagctg cagccgaccc atgtccgggg ctctgccctt tgctctgcag cttttctatg
       61 tcccgaggct ctggagagtg ggcgtgggag tagccctagc tgaggctcca aggtcctccg
      121 ggctgtttag ggggccccag gcgatatcca cgttcggatc ctggctcgct gccaggggag
      181 ggagctcggg tttcatttcc gcggaccctc ctgcctgggc cgcagccgcc gccgccgcga
      241 tgcctagcaa gttcagctgc cgaaagctcc gggagaccgg ccagaggttc gagagttttc
      301 tggccgaacg tggactggac ctggagacag atcgtgagcg gctgcggacg atttacaacc
      361 acgacttcaa gcccagctat gggacccctg cccctggctt ctcctccatg ctgtatggaa
      421 tgaagatcgc aaatctggcc ttcgtcacca agactcgggt caggttcttc aaactagacc
      481 gctgggctga tgtgcagtta ccagaaaaga ggcgaataaa gccagggtcg aacatcagca
      541 aacaacacag atcactgttg gccaggatct ttcacgacag ggctgagtac cttcatggga
      601 agcatggggt agacgtggag gtccaggggc cccatgaagc ccgagacggg caactcctta
      661 tccacctgga tttgaaccgc aaggaggtac taaccctacg gcttcggaac ggcggaagca
      721 aacctgtcac cctcactcac ctattcccac tgtgctggac gccccagttt gtcttctacc
      781 atggagaaca ggacctgccc tgcccactgg gccccggtga aagctatgaa ctccacatct
      841 actgtaagac cagcattgtg ggttacttcc cagccactgt cctctgggaa ctcctgggac
      901 ccggggagtc gggagcagaa ggagcagaaa ctttctacat tgcccgattc ctggcggctg
      961 tcgcccacag tcccctggct gcccagttga aacccacaac tcccttcaaa cgcccccctc
     1021 ggctcaccag aaactctgtg ttgaccaacc ggatcgagga aggagagagg cccgaccgag
     1081 ccaagggcta tgaactagag ctaagtttgg ccctggggac ctattaccca cccatcctcc
     1141 tccgacaact gctccctacc cttcttcagg gaccaagtat cttcactgcc ccaaaggagg
     1201 ttgctgagat caaggcccag ctggagacaa ccctgaaatc caggaactat gaggtgaaac
     1261 tccggctgct gctgcacctg gaagagctgc agatggagca tgacatccgg cactatgacc
     1321 tggactcggt acccatgacc tgggaccctg tggaccagaa tcccaggctg ctcaccctgg
     1381 aggttcctgg tgtcgcagag agccgtccct cagtgctacg aggtgaccac ctttttgccc
     1441 ttttgtcctc tgagacccaa caggacgacc ctgtcaccta caagggtttc gtgcacaagg
     1501 tggaactgga ccgtgtcaag ctgagctttt ctacaagcct cctgagccga tttgtggatg
     1561 ggctgacctt caaggtgaac tttaccttca accgccagcc ccttcgggtc cagcaccggg
     1621 ccctagagtt gacggggcgc tgggtgctat ggcccatgct ttttcctgtg gcctcccgtg
     1681 gggtctcgtt gctgccctca gatgtgaagt tcaagctgta cgatcggagt ctggagtcaa
     1741 accctgagca actgcaggcc atgaagcaca ttgtgagggg taccacccgg cctgccccct
     1801 acatcatctt tgggcctcca ggtaccggca agactgtcac attagtggag gccatcaaac
     1861 aggtagtgaa gcatttgccc aaagcccaca tcctggcctg tgctccatcc aactcagggg
     1921 ctgacctcct ctgtcagcgg ctccgggtcc acctgcccag ctccatctac cgtctcctgg
     1981 cccccagcag ggacatccga atggtgcctg aggacattaa gacctgctgt aactgggatg
     2041 ctaagaaggg agaatatgtg tatcctgcta agaagcacct gcagcaatat cgggtcttaa
     2101 ttaccaccct catcactgcc agcaggttgg tgtcagccca gtttcccatc gatcacttca
     2161 cacacatctt catcgatgag gctggccact gcatggagcc tgagagtctg gtggccatag
     2221 caggactgat ggatgtcaag gaaacgggca atcccggagg gcagctggta ctggcaggag
     2281 accctcggca gctggggcct gtgctgcgct cgccactagc cctgaagcat ggacttggct
     2341 actctctgct agagcgcctg ctcgcctaca actccttgta taagaagggc cccaatggct
     2401 atgaccccca gttcatcacc aaactgctcc gcaactacag gtctcacccc accatcctgg
     2461 acatccctaa ccagctgtac tacgacggag agctgcaggc ctgcgcagat gtggtggatc
     2521 gagaacggtt ctgccgctgg gaggggctgc ctcagcaggg cttccccatc attttccatg
     2581 gtgtaatggg caaagatgag agagaaggca atagcccatc cttcttcaac cctgaagagg
     2641 ctgctacagt gacgtcatac ctgaaacaac tcctggcccc ttcctccaag aagggtaaag
     2701 cccgcctgag cccccgaaat gtgggcgtca tctccccgta ccggaagcag gtagaaaaaa
     2761 tccgttactg catcacaaaa cttgaccgag aacttcgcgg actggatgac atcaaagatt
     2821 tgaaggtggg ctctgtggaa gagttccaag gccaagaacg cagcgtcatc ctcatctcca
     2881 ccgtccgaag cagccagagc tttgtacagc tggatctaga ctttaacctc ggtttcctta
     2941 agaaccccaa gaggttcaat gttgctgtga cccgagccaa ggctttgctc atcgtagtgg
     3001 gcaaccccct cctcctaggc cacgacccag actggaaaac gttcctggag ttctgtaaag
     3061 aaaacggggg atataccggg tgcccctttc ctgccaaact ggacctgcag cagggacagg
     3121 acttgctcca aggtctgagc aaactcagcc cctctacctc agggccccgc cgtcaccaga
     3181 atctccccca ggagcgggag ggtgaagggg gcctgccctt acaagtggag ccagagtgga
     3241 gaaatgagct ctgaggccac agccgcccgc cttctcacac cagccaagcc ttattgctgc
     3301 ctatccctga cccagaaccc agctctcctg tccctgcaag agatgggaag gccgggaagt
     3361 ttacagccca gaccattccg ccccttcctc tgctagggaa gacaacccaa gctgctaaaa
     3421 ctcggaggaa gggggaggaa gaaagctttt tttttttttt aaaccctctc ctttgcagtg
     3481 ctggggatcg aacccagagc ctcaaatatg ctaggcaagc actctgcccc tgagctgctt
     3541 taagaaaaac aaaatgctgt tctatgcaaa a
//
