LOCUS       NM_001254762            1331 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus motile sperm domain containing 3 (Mospd3), transcript
            variant 2, mRNA.
ACCESSION   NM_001254762
VERSION     NM_001254762.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1331)
  AUTHORS   Huang,X., Liu,X. and Lin,J.
  TITLE     Methylation of lncSHGL promotes adipocyte differentiation by
            regulating miR-149/Mospd3 axis
  JOURNAL   Cell Cycle 22 (21-22), 2361-2380 (2023)
   PUBMED   38057958
  REMARK    GeneRIF: Methylation of lncSHGL promotes adipocyte differentiation
            by regulating miR-149/Mospd3 axis.
REFERENCE   2  (bases 1 to 1331)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1331)
  AUTHORS   O'Leary,J. and Osborne,L.R.
  TITLE     Global analysis of gene expression in the developing brain of
            Gtf2ird1 knockout mice
  JOURNAL   PLoS One 6 (8), e23868 (2011)
   PUBMED   21909369
REFERENCE   4  (bases 1 to 1331)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   5  (bases 1 to 1331)
  AUTHORS   Pall,G.S., Wallis,J., Axton,R., Brownstein,D.G., Gautier,P.,
            Buerger,K., Mulford,C., Mullins,J.J. and Forrester,L.M.
  TITLE     A novel transmembrane MSP-containing protein that plays a role in
            right ventricle development
  JOURNAL   Genomics 84 (6), 1051-1059 (2004)
   PUBMED   15533722
REFERENCE   6  (bases 1 to 1331)
  AUTHORS   Yamaguchi,T., Kubota,T., Kanematsu,T., Nakayama,K., Hirata,M. and
            Yamamoto,T.
  TITLE     Hypersensitivity to pentylenetetrazol-induced convulsion in mice
            lacking the PLC-related inactive protein-1
  JOURNAL   Brain Res 1025 (1-2), 237-240 (2004)
   PUBMED   15464766
REFERENCE   7  (bases 1 to 1331)
  AUTHORS   Suzuki,H., Fukunishi,Y., Kagawa,I., Saito,R., Oda,H., Endo,T.,
            Kondo,S., Bono,H., Okazaki,Y. and Hayashizaki,Y.
  TITLE     Protein-protein interaction panel using mouse full-length cDNAs
  JOURNAL   Genome Res 11 (10), 1758-1765 (2001)
   PUBMED   11591653
REFERENCE   8  (bases 1 to 1331)
  AUTHORS   McClive,P., Pall,G., Newton,K., Lee,M., Mullins,J. and Forrester,L.
  TITLE     Gene trap integrations expressed in the developing heart: insertion
            site affects splicing of the PT1-ATG vector
  JOURNAL   Dev Dyn 212 (2), 267-276 (1998)
   PUBMED   9626501
REFERENCE   9  (bases 1 to 1331)
  AUTHORS   Forrester,L.M., Nagy,A., Sam,M., Watt,A., Stevenson,L.,
            Bernstein,A., Joyner,A.L. and Wurst,W.
  TITLE     An induction gene trap screen in embryonic stem cells:
            Identification of genes that respond to retinoic acid in vitro
  JOURNAL   Proc Natl Acad Sci U S A 93 (4), 1677-1682 (1996)
   PUBMED   8643689
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC148018.3, CK617131.1, BQ445267.1 and AW050147.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR,
            compared to variant 1. Variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC003880.1, AK088731.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849383, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-49                AC148018.3         232742-232790       c
            50-439              CK617131.1         1-390
            440-1027            BQ445267.1         6-593
            1028-1331           AW050147.1         1-304               c
FEATURES             Location/Qualifiers
     source          1..1331
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 76.59 cM"
     gene            1..1331
                     /gene="Mospd3"
                     /gene_synonym="1190005J19Rik; 5133401H10Rik; Gtig2; R124"
                     /note="motile sperm domain containing 3"
                     /db_xref="GeneID:68929"
                     /db_xref="MGI:MGI:1916179"
     exon            1..438
                     /gene="Mospd3"
                     /gene_synonym="1190005J19Rik; 5133401H10Rik; Gtig2; R124"
                     /inference="alignment:Splign:2.1.0"
     CDS             234..941
                     /gene="Mospd3"
                     /gene_synonym="1190005J19Rik; 5133401H10Rik; Gtig2; R124"
                     /note="gene trap integration gene 2"
                     /codon_start=1
                     /product="motile sperm domain-containing protein 3"
                     /protein_id="NP_001241691.1"
                     /db_xref="CCDS:CCDS19771.1"
                     /db_xref="GeneID:68929"
                     /db_xref="MGI:MGI:1916179"
                     /translation="MRRGAPQDQELVGPGAPGRGSRGSPPSSGPVVPVLVFPPDLVFR
                     ADQRSGPRQLLTLYNPTGTALRFRVLCTAPAKYTVFDAEGYVKPQSCIDIVIRHVAPV
                     PSHYDVQDRFRIELSEEGTEGRVVGRKDITSVLRAPAYPLELQGHSEPTPNPGPPVWT
                     GLTPARHLQENAPQQLATSSFLLFLLAGVISVAFLLLPLQDELGSQLPQVLHVSLGQK
                     LVAAYVLGLLTMVLLRT"
     exon            439..514
                     /gene="Mospd3"
                     /gene_synonym="1190005J19Rik; 5133401H10Rik; Gtig2; R124"
                     /inference="alignment:Splign:2.1.0"
     exon            515..744
                     /gene="Mospd3"
                     /gene_synonym="1190005J19Rik; 5133401H10Rik; Gtig2; R124"
                     /inference="alignment:Splign:2.1.0"
     exon            745..909
                     /gene="Mospd3"
                     /gene_synonym="1190005J19Rik; 5133401H10Rik; Gtig2; R124"
                     /inference="alignment:Splign:2.1.0"
     exon            910..1318
                     /gene="Mospd3"
                     /gene_synonym="1190005J19Rik; 5133401H10Rik; Gtig2; R124"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1298..1303
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mospd3"
                     /gene_synonym="1190005J19Rik; 5133401H10Rik; Gtig2; R124"
                     /note="hexamer: AATACA"
     polyA_site      1318
                     /gene="Mospd3"
                     /gene_synonym="1190005J19Rik; 5133401H10Rik; Gtig2; R124"
                     /note="major polyA site"
ORIGIN      
        1 ggggcctata ggaacctggg gcccagctgg caggagagga ggtttgggaa ccggggcccg
       61 gggctgcagg atccacatct agcggggttc caaggcagtg gtgacatcag gcctcgctct
      121 gctcatgatc tccccctgtc ctcttttcat ccatcgcgtc actagcccta aactctaaga
      181 ccctcttgtc ctcctgagct ctgccctcgg atgtccgacc gcccagagcc tgcatgcgcc
      241 gtggggcgcc ccaggaccag gagctggtgg gtccgggggc ccctgggcgg gggtcccggg
      301 gctcccctcc ttcctcagga cccgttgtcc cggtgctggt ctttcccccg gatctagtat
      361 tcagggcgga ccagagaagt ggaccccggc agctgctgac cctctacaac cccacgggaa
      421 ctgcgcttcg cttccgagtt ctgtgcacag cacctgccaa atacacggta ttcgatgcag
      481 agggatatgt gaagcctcag tcctgcattg acattgtgat acggcacgtg gcccccgtcc
      541 ccagccacta tgacgtccag gacagattcc gcattgagct gtctgaggag gggactgagg
      601 gacgagtggt tggaagaaaa gacatcacct ctgttcttcg agccccagcg taccccctgg
      661 agcttcaggg acattctgag ccaacgccca acccagggcc tcctgtgtgg acaggactga
      721 ccccagccag acatcttcag gagaatgccc cccagcagct ggccaccagc tccttcctgc
      781 tcttcttgct ggcaggcgtc atctctgtgg ccttcctgct cctaccactg caggatgagc
      841 ttggcagcca gctgcctcaa gtcctgcacg tgtccctggg acagaagctg gttgcggcct
      901 acgtcttagg cctcctcacc atggtgctcc tccggacctg aactctcagc tgaacccacc
      961 tcacccaccc tctccttcgc aggcagggac ctaaggcagc cactgtgatg tttgcacctt
     1021 gctcctcctc cctcgcttcc gcccatccgt tgctcctcct ccctcgcttc cgcccatccg
     1081 ttgctcctcc tccctcgctt ccgcccatcc gttgctcctc ctccctcgct tccgcccatc
     1141 cgttgctcct cctccctcgt ttccgcccat ccgttgctcc tcctccctcg cttccgccca
     1201 tccgttgctc ctcctccctc gcttccgccc atccgttgat tgtcagcctc cccacagcaa
     1261 gcacctggga tttgtactca ttttccaagt tgattaaaat acattttaaa aatcaaaaaa
     1321 aaaaaaaaaa a
//
