LOCUS       NM_029730               4095 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus motile sperm domain containing 2 (Mospd2), transcript
            variant 1, mRNA.
ACCESSION   NM_029730 XM_136156 XM_891689 XM_899674 XM_899680 XM_899687
            XM_899692 XM_899707 XM_910453 XM_921622 XM_921629 XM_921633
            XM_921640 XM_921646 XM_921656 XM_982908 XM_982943 XM_982977
            XM_983014 XM_983049 XM_983093 XM_983132
VERSION     NM_029730.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4095)
  AUTHORS   Yacov,N., Kafri,P., Salem,Y., Propheta-Meiran,O., Feldman,B.,
            Breitbart,E. and Mendel,I.
  TITLE     MOSPD2 is a therapeutic target for the treatment of CNS
            inflammation
  JOURNAL   Clin Exp Immunol 201 (2), 105-120 (2020)
   PUBMED   32353176
  REMARK    GeneRIF: MOSPD2 is a therapeutic target for the treatment of CNS
            inflammation.
REFERENCE   2  (bases 1 to 4095)
  AUTHORS   Hughes,D.S., Keynes,R.J. and Tannahill,D.
  TITLE     Extensive molecular differences between anterior- and
            posterior-half-sclerotomes underlie somite polarity and spinal
            nerve segmentation
  JOURNAL   BMC Dev Biol 9, 30 (2009)
   PUBMED   19463158
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL732426.6, AK035985.1, AK031405.1 and AL669950.11.
            
            On Mar 14, 2014 this sequence version replaced NM_029730.3.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219382.79381.1, AK035985.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164137
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-40                AL732426.6         40730-40769         c
            41-990              AK035985.1         1-950
            991-1124            AK031405.1         916-1049
            1125-2055           AK035985.1         1084-2014
            2056-4095           AL669950.11        201819-203858       c
FEATURES             Location/Qualifiers
     source          1..4095
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 76.75 cM"
     gene            1..4095
                     /gene="Mospd2"
                     /gene_synonym="2410013I23Rik"
                     /note="motile sperm domain containing 2"
                     /db_xref="GeneID:76763"
                     /db_xref="MGI:MGI:1924013"
     exon            1..161
                     /gene="Mospd2"
                     /gene_synonym="2410013I23Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             153..1709
                     /gene="Mospd2"
                     /gene_synonym="2410013I23Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     motile sperm domain-containing protein 2"
                     /codon_start=1
                     /product="motile sperm domain-containing protein 2 isoform
                     1"
                     /protein_id="NP_084006.2"
                     /db_xref="CCDS:CCDS53241.1"
                     /db_xref="GeneID:76763"
                     /db_xref="MGI:MGI:1924013"
                     /translation="MAENNAQNKAKLISETRRRFEAEYVTEKSEKYDSRDVERLQQDD
                     NWVESYLYWRHNVVDETLKMLDESFQWRKEFSVNDLSESSIPRWLLELGGIYLHGYDK
                     EGNKLFWIRVKYHIKDQKTIMDKKKLIAFWLERYAKRENGKPITVMFDMSETGLNSID
                     MDFVRFIINCFKVYYPKYLSKIVIFDMPWIMNAAFKIVKSWLGPEAVSLLKFTSKNEI
                     QEYVSVEYLPPHMGGTDPFKYSYPPLVDDDFQTPLCENGPIASEDETSSKEDIEGDGK
                     ETLETISNEEPPALSEKSNPTESVSKKDENEKVDSKTKTFKKPLSVFKGPLLHISPAE
                     ELYFGSIESGEKKTLIVLTNVTKNIVAFKVRTTAPEKYRVKPSNSSCDPGASIDIIVS
                     PHGGLTVSAQDRFLIMAAEMEQSSGTGPAELSQFWKEVPRNKVMEHRLRCHTVESSKP
                     NSLMLKDSISTMSDKTSEDLYLQLNRLLESNRKLEDQLQRSIWFQQLLLALTMVLLAF
                     VVSFFYSLYN"
     exon            162..231
                     /gene="Mospd2"
                     /gene_synonym="2410013I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            232..387
                     /gene="Mospd2"
                     /gene_synonym="2410013I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            388..474
                     /gene="Mospd2"
                     /gene_synonym="2410013I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            475..629
                     /gene="Mospd2"
                     /gene_synonym="2410013I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            630..690
                     /gene="Mospd2"
                     /gene_synonym="2410013I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            691..729
                     /gene="Mospd2"
                     /gene_synonym="2410013I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            730..854
                     /gene="Mospd2"
                     /gene_synonym="2410013I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            855..1031
                     /gene="Mospd2"
                     /gene_synonym="2410013I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1032..1144
                     /gene="Mospd2"
                     /gene_synonym="2410013I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1145..1241
                     /gene="Mospd2"
                     /gene_synonym="2410013I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1242..1338
                     /gene="Mospd2"
                     /gene_synonym="2410013I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1339..1468
                     /gene="Mospd2"
                     /gene_synonym="2410013I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1469..1571
                     /gene="Mospd2"
                     /gene_synonym="2410013I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1572..4095
                     /gene="Mospd2"
                     /gene_synonym="2410013I23Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4073..4078
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mospd2"
                     /gene_synonym="2410013I23Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4095
                     /gene="Mospd2"
                     /gene_synonym="2410013I23Rik"
                     /note="major polyA site"
ORIGIN      
        1 ttccttctac gttccggtgt cacgcgaccc cctccccccc tccctccctt cttgatctac
       61 ctttgggctg ggctggctgg tgatgagaca cttggctgca ggctgtggaa ggagcgacgg
      121 gtacaaccac aataggttcc gcgactgtga ccatggccga gaataacgct cagaataaag
      181 ccaagctaat ctcagagacc cggcggagat tcgaagctga gtatgtgaca gaaaagtcag
      241 aaaaatatga ttcacgtgat gttgaaaggc ttcagcaaga tgataactgg gttgaaagtt
      301 acttatactg gagacataac gttgtggatg aaaccctgaa gatgcttgac gagagttttc
      361 agtggaggaa agagttctct gtcaatgacc ttagtgaatc ctctattcca agatggttat
      421 tagaacttgg tggtatttat ctccatggtt atgacaaaga aggtaacaaa ttattctgga
      481 tcagagtgaa gtatcacata aaagatcaga aaaccataat ggacaagaag aagctcatag
      541 cattctggtt ggaacgatat gccaagagag aaaacgggaa acctatcaca gtgatgtttg
      601 acatgtccga aactggactc aatagcatag acatggactt tgtacgattt atcatcaact
      661 gctttaaggt gtattacccc aaatacctct caaaaatagt gatctttgat atgccttgga
      721 taatgaatgc tgctttcaaa attgtgaaaa gctggcttgg ccccgaagca gtaagcttgt
      781 tgaagtttac aagtaagaat gaaatccagg agtatgtcag tgtggaatac ctgcctcccc
      841 acatgggtgg gacagatcca ttcaagtata gctacccacc actggtagat gatgacttcc
      901 agacaccact ttgtgaaaat gggccaattg ccagtgagga tgaaacctca agtaaggaag
      961 atatagaagg tgatggtaag gaaaccttgg aaacgatttc taatgaggag ccaccagctc
     1021 tgtctgaaaa gagtaaccca actgagtctg tttccaaaaa agatgaaaat gaaaaagttg
     1081 attcaaagac gaaaactttt aaaaagccat tgagtgtttt taaaggaccc ttattacaca
     1141 tcagcccagc agaggaatta tattttggaa gcattgaatc tggagagaag aaaactctga
     1201 tagtgttgac aaatgtcaca aaaaatattg tggcctttaa ggtgagaacc acagctccag
     1261 aaaaatacag ggtcaagcct agcaacagca gctgcgatcc cggagcttcc attgatatca
     1321 tcgtttctcc acacggaggt ttaaccgtct cagctcaaga ccggttcctg atcatggctg
     1381 ccgaaatgga gcagtcatct ggcactgggc ctgcagaact gagtcagttc tggaaagagg
     1441 ttccaagaaa caaggtgatg gagcacaggc taagatgtca caccgttgag agcagcaaac
     1501 cgaacagtct catgctgaag gacagcattt ccaccatgtc agataaaacc agtgaagatc
     1561 tgtacctgca actcaatcgt ttactagaaa gcaataggaa actggaagac caactacagc
     1621 gctctatctg gttccaacag ctactgcttg ccttaacaat ggtcttgctt gcttttgttg
     1681 tttctttctt ttattcatta tacaattaaa agtggcacct ggtcaaaacc ataaaactcc
     1741 ttcaggcatt atctggagaa ggtatacaga tcccacccaa acctttccac acatctgggc
     1801 ttcctacaag gaaataaagc agcacatgga agggtgccta tcttggaaat gagttgtttg
     1861 gctagagaga cgtttgaggc attgattatt agagactata gctagttagg aaactaagta
     1921 aacgtatgtg cattgtacaa attaatagca taaacgtaat ttatttttct ttttgatttg
     1981 aacgctttca aagcaaattt ttatcatgta aatacactag ctgaactgaa aagactaata
     2041 tgctttgttg tagccaaaaa aaaaatgtag tctgcttttt taaaaattac agaattacta
     2101 gccaagctga cttattagtt tttctatact atgtatgtaa aatatgtata ttaaaaaagg
     2161 aagcatactt aaataattta tgtgatcatg actttgtaac ttggagaact acttccagat
     2221 gatagtcgat atgcttttgg aatgtaaagc tatttaatgc caaacctcct tagcctttgt
     2281 ttctcagtgt cactgagcag cctgcctctt attaaatccg ggctctttaa tgaatactct
     2341 gttttcgata caatatgaaa agctacatgt ggttgggttt tctttgattt ctcttattag
     2401 tgcccagaag gaacgtctct gaaagagccc ccctttctag tcaattctat gcagtttccc
     2461 tatgtttgga cactgaactt tttgcctggg tttattataa ggccctactt ttccattgtg
     2521 ccatcttcat cttcattcca gggcaaagga atctcctctg tggaccacaa atgatgccac
     2581 cttcaccctc gcttttaaat gaaaggcatt attatataac attgtttgaa agtctagttg
     2641 tccattacta taaataaccg tgggttccaa atggttcttg tgaaaattgt tgatgagaag
     2701 gaaactttaa aagtattcat gtgtgcaaat ataaaagcaa agcagaaagg cttagagaat
     2761 gggaagaatt atcacttccc gtggcttctc tggcccactg actgctctgc cttccgtata
     2821 cttagactca ttcatatggc tcctaaattc ctatagagat acaccttgca gaagcagagg
     2881 ctaatgaaat agctttgtgt aatcattaac atgaccagtt tctgtcactt tcgattcaaa
     2941 tccatatctg cctttttaag gaagaaagtc ctctgcctag caaatgaata ttccgccatg
     3001 tttggagagt tgttcttctc aggagtagag ttgggggctc tcatcttgaa gccgttgatt
     3061 cccagaccga gtttggagga gtgatgtaat ggagctcctt aagaagtcgg ccgaggaaag
     3121 aaaaccttaa agggacacta gtgtgatgct ttgtcttaat gtgggttttt ctgtttcagt
     3181 ttgccacctc cagatgtgaa acagactgca gtccacacta agtactatgt ccctgtatgt
     3241 tcacagtgac ttcccaagtg gtagagttgg gggccttaat ataatgtcat cccaaagtat
     3301 ctgtctatgc ttttcattcc tcatcagata aacaggcaat taattagcca agatgaggaa
     3361 tataattgtc ctaacagtgt ccctttaatg tttcataagg aaatcatgtt gatacactaa
     3421 acacccttct ttgcttgttg tctggtcagt tgaatttagt aacatcttgt tagcatttct
     3481 gtgtggtgaa tgtgactaaa aaggactttg ggaaattaac ataatgtcaa cagtaactgg
     3541 actcttctgc taatcttgat taatctatag agttacattt gattttgtcc tgtctttatt
     3601 tggtttaatc taatcatatg tgcatgatta tttttagtat tctgatcaat aattttctct
     3661 ttaatcatgt cattgctttt tcatgatcaa attaccagag attttcattt tgatttttat
     3721 tttcactcgg gaatggaaat taatacattt tccatgaaaa cattaataaa agatcattag
     3781 cttgatctgc aagtagccta aaatacaaat gctggttaac ctagtctcaa atttcataaa
     3841 accataactt ttatatcttg ccactaattt tgactggatt taatagcact ttattgtaca
     3901 attataaaaa atatattcct ggaattgttg ccagtgtaat ttctctaacg ttctggtgct
     3961 tttcatatat tttcagtatt tttattacta tattggtatt ttctttgtat aaattgatca
     4021 aaagaacatg ttttctattt taatatgttt tagaaaataa ttacatttat gaaataaata
     4081 tcatcaggaa aaaaa
//
