LOCUS       NM_194269                631 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus MORN repeat containing 2 (Morn2), transcript variant
            1, mRNA.
ACCESSION   NM_194269
VERSION     NM_194269.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 631)
  AUTHORS   Liu,Y., Li,T., Shi,M., Wan,Y., Li,H., Zhang,M., Wang,Z., Wang,S.,
            Lv,Y., Lu,G., Liu,H., Zhang,H. and Huang,T.
  TITLE     MORN2 regulates the morphology and energy metabolism of
            mitochondria and is required for male fertility in mice
  JOURNAL   J Transl Med 22 (1), 240 (2024)
   PUBMED   38443933
  REMARK    GeneRIF: MORN2 regulates the morphology and energy metabolism of
            mitochondria and is required for male fertility in mice.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 631)
  AUTHORS   Morita,M., Kajiye,M., Sakurai,C., Kubo,S., Takahashi,M.,
            Kinoshita,D., Hori,N. and Hatsuzawa,K.
  TITLE     Characterization of MORN2 stability and regulatory function in
            LC3-associated phagocytosis in macrophages
  JOURNAL   Biol Open 9 (6) (2020)
   PUBMED   32414768
  REMARK    GeneRIF: Characterization of MORN2 stability and regulatory
            function in LC3-associated phagocytosis in macrophages.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 631)
  AUTHORS   Choi,Y.J., Hwang,K.C., Park,J.Y., Park,K.K., Kim,J.H., Park,S.B.,
            Hwang,S., Park,H., Park,C. and Kim,J.H.
  TITLE     Identification and characterization of a novel mouse and human MOPT
            gene containing MORN-motif protein in testis
  JOURNAL   Theriogenology 73 (3), 273-281 (2010)
   PUBMED   19913896
  REMARK    GeneRIF: MOPT is associated with dynamic regulation of acrosome
            biogenesis during late spermiogenesis.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC132910.8.
            
            On Nov 8, 2022 this sequence version replaced NM_194269.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Both variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB273496.1, CJ044220.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849379
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-110               AC132910.8         48449-48558         c
            111-164             AC132910.8         46408-46461         c
            165-271             AC132910.8         44210-44316         c
            272-408             AC132910.8         43137-43273         c
            409-631             AC132910.8         41310-41532         c
FEATURES             Location/Qualifiers
     source          1..631
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 50.63 cM"
     gene            1..631
                     /gene="Morn2"
                     /gene_synonym="Mopt"
                     /note="MORN repeat containing 2"
                     /db_xref="GeneID:378462"
                     /db_xref="MGI:MGI:2674071"
     exon            1..110
                     /gene="Morn2"
                     /gene_synonym="Mopt"
                     /inference="alignment:Splign:2.1.0"
     exon            111..164
                     /gene="Morn2"
                     /gene_synonym="Mopt"
                     /inference="alignment:Splign:2.1.0"
     exon            165..271
                     /gene="Morn2"
                     /gene_synonym="Mopt"
                     /inference="alignment:Splign:2.1.0"
     CDS             272..511
                     /gene="Morn2"
                     /gene_synonym="Mopt"
                     /note="protein containing single MORN motif in testis;
                     MORN motif protein in testis"
                     /codon_start=1
                     /product="MORN repeat-containing protein 2"
                     /protein_id="NP_919245.1"
                     /db_xref="CCDS:CCDS37703.1"
                     /db_xref="GeneID:378462"
                     /db_xref="MGI:MGI:2674071"
                     /translation="MNGFGRLEHFSGAVYEGQFKDNMFHGLGTYTFPTGAKYTGNFNE
                     NRVEGEGEYTDTQGLQWCGNFHFTAAPGLKLKLYM"
     exon            272..408
                     /gene="Morn2"
                     /gene_synonym="Mopt"
                     /inference="alignment:Splign:2.1.0"
     exon            409..631
                     /gene="Morn2"
                     /gene_synonym="Mopt"
                     /inference="alignment:Splign:2.1.0"
     regulatory      609..614
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Morn2"
                     /gene_synonym="Mopt"
                     /note="hexamer: AATAAA"
     polyA_site      631
                     /gene="Morn2"
                     /gene_synonym="Mopt"
                     /note="major polyA site"
ORIGIN      
        1 agcaaccgag gcccgctctg tcctagagcc cagctccctc cagcctgccg agctggcgag
       61 cctaggggaa tcgcagagtc gcgaaagcct gtccttcacg tctccatcaa cttcgtcaga
      121 agtatataag atcaaattta tatttccaaa tggagacaca tacgatggcg actgcacaag
      181 aactacctct gggatctgtg agagaaacgg gacaggcacg cacaccacgc cgaacgggat
      241 tgtctacaca ggaagctgga aagatgacaa gatgaatggc tttggaagac ttgaacattt
      301 ttcgggcgct gtgtatgaag gacagtttaa ggacaacatg tttcatggac tggggactta
      361 cacattccca actggggcaa agtacactgg aaatttcaat gaaaataggg tagaaggtga
      421 gggagaatac actgacaccc aaggcctgca gtggtgtggt aacttccact tcacagctgc
      481 ccccggcctg aaactaaagc tctacatgta gacctgctgc cttaacgctg agatgtggcc
      541 tctgcaaccc cccttaggca aagcaactga accttctgct aaagtgacct gccctcttcc
      601 gtaagtccaa taaagttgtc atgcacccac a
//
