LOCUS       NM_001168226            1880 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus mortality factor 4 like 2 (Morf4l2), transcript
            variant 3, mRNA.
ACCESSION   NM_001168226
VERSION     NM_001168226.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1880)
  AUTHORS   Brandsma,I., Sato,K., van Rossum-Fikkert,S.E., van Vliet,N.,
            Sleddens,E., Reuter,M., Odijk,H., van den Tempel,N.,
            Dekkers,D.H.W., Bezstarosti,K., Demmers,J.A.A., Maas,A.,
            Lebbink,J., Wyman,C., Essers,J., van Gent,D.C., Baarends,W.M.,
            Knipscheer,P., Kanaar,R. and Zelensky,A.N.
  TITLE     HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required
            for Mouse Spermatogenesis
  JOURNAL   Cell Rep 27 (13), 3790-3798 (2019)
   PUBMED   31242413
REFERENCE   2  (bases 1 to 1880)
  AUTHORS   Jacquet,K., Fradet-Turcotte,A., Avvakumov,N., Lambert,J.P.,
            Roques,C., Pandita,R.K., Paquet,E., Herst,P., Gingras,A.C.,
            Pandita,T.K., Legube,G., Doyon,Y., Durocher,D. and Cote,J.
  TITLE     The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1
            through Direct H4K20me Binding and H2AK15 Acetylation
  JOURNAL   Mol Cell 62 (3), 409-421 (2016)
   PUBMED   27153538
REFERENCE   3  (bases 1 to 1880)
  AUTHORS   Lumayag,S., Haldin,C.E., Corbett,N.J., Wahlin,K.J., Cowan,C.,
            Turturro,S., Larsen,P.E., Kovacs,B., Witmer,P.D., Valle,D.,
            Zack,D.J., Nicholson,D.A. and Xu,S.
  TITLE     Inactivation of the microRNA-183/96/182 cluster results in
            syndromic retinal degeneration
  JOURNAL   Proc Natl Acad Sci U S A 110 (6), E507-E516 (2013)
   PUBMED   23341629
REFERENCE   4  (bases 1 to 1880)
  AUTHORS   Tominaga,K., Matzuk,M.M. and Pereira-Smith,O.M.
  TITLE     MrgX is not essential for cell growth and development in the mouse
  JOURNAL   Mol Cell Biol 25 (12), 4873-4880 (2005)
   PUBMED   15923606
  REMARK    GeneRIF: Data show that MRGX is ubiquitously expressed in all
            tissues of adult mice and also during embryogenesis, and overlaps
            with its homolog Mrg15.
REFERENCE   5  (bases 1 to 1880)
  AUTHORS   Doyon,Y., Selleck,W., Lane,W.S., Tan,S. and Cote,J.
  TITLE     Structural and functional conservation of the NuA4 histone
            acetyltransferase complex from yeast to humans
  JOURNAL   Mol Cell Biol 24 (5), 1884-1896 (2004)
   PUBMED   14966270
REFERENCE   6  (bases 1 to 1880)
  AUTHORS   Bertram,M.J. and Pereira-Smith,O.M.
  TITLE     Conservation of the MORF4 related gene family: identification of a
            new chromo domain subfamily and novel protein motif
  JOURNAL   Gene 266 (1-2), 111-121 (2001)
   PUBMED   11290425
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL671887.18, BY141735.1, AK160012.1 and BC075653.1.
            
            Transcript Variant: This variant (3) differs in the 5' UTR compared
            to variant 1. Variants 1 through 7 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK160012.1, AK129038.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164141
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-24                AL671887.18        96138-96161         c
            25-74               BY141735.1         1-50
            75-1859             AK160012.1         2-1786
            1860-1880           BC075653.1         1934-1954
FEATURES             Location/Qualifiers
     source          1..1880
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 59.1 cM"
     gene            1..1880
                     /gene="Morf4l2"
                     /gene_synonym="2410017O14Rik; mKIAA0026; Mrgx; Sid393p"
                     /note="mortality factor 4 like 2"
                     /db_xref="GeneID:56397"
                     /db_xref="MGI:MGI:1927167"
     exon            1..143
                     /gene="Morf4l2"
                     /gene_synonym="2410017O14Rik; mKIAA0026; Mrgx; Sid393p"
                     /inference="alignment:Splign:2.1.0"
     exon            144..233
                     /gene="Morf4l2"
                     /gene_synonym="2410017O14Rik; mKIAA0026; Mrgx; Sid393p"
                     /inference="alignment:Splign:2.1.0"
     exon            234..310
                     /gene="Morf4l2"
                     /gene_synonym="2410017O14Rik; mKIAA0026; Mrgx; Sid393p"
                     /inference="alignment:Splign:2.1.0"
     exon            311..1870
                     /gene="Morf4l2"
                     /gene_synonym="2410017O14Rik; mKIAA0026; Mrgx; Sid393p"
                     /inference="alignment:Splign:2.1.0"
     CDS             335..1201
                     /gene="Morf4l2"
                     /gene_synonym="2410017O14Rik; mKIAA0026; Mrgx; Sid393p"
                     /note="transcription factor-like protein Mrgx; sid 393;
                     MORF-related gene X protein"
                     /codon_start=1
                     /product="mortality factor 4-like protein 2"
                     /protein_id="NP_001161698.1"
                     /db_xref="CCDS:CCDS30422.1"
                     /db_xref="GeneID:56397"
                     /db_xref="MGI:MGI:1927167"
                     /translation="MSSRKQASQTRGQQSAEEDNFKKPTRSNMQRSKMRGAASGKKSA
                     GSQPKNLDPALPGRWGGRSAENPPSGSVRKTRKNKQKAPGNGDGGSTSEVPQPPRKKR
                     ARADPTVESEEAFKSRMEVKVKIPEELKPWLVEDWDLVTRQKQLFQLPAKKNVDAILE
                     EYANCKKSQGNVDNKEYAVNEVVGGIKEYFNVMLGTQLLYKFERPQYAEILLAHPDAP
                     MSQIYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDY
                     KVASADYHRKAL"
     polyA_site      1414
                     /gene="Morf4l2"
                     /gene_synonym="2410017O14Rik; mKIAA0026; Mrgx; Sid393p"
                     /note="major polyA site"
     polyA_site      1718
                     /gene="Morf4l2"
                     /gene_synonym="2410017O14Rik; mKIAA0026; Mrgx; Sid393p"
ORIGIN      
        1 ggctgatggg ctaagcccgc ctccagggtg acgtgtctgc ctatggatat cagttgccag
       61 agaaacctgg ctttactatg gcggttggag gagcagcagt gatcacacgt cggctgctgg
      121 agagagctgg attctcgttt caggtcatca tcagaaaagc taagtttgct atacagtaag
      181 gatcaggaga tctgaccctg gttgcagaac cattcctggt tgcagaatac agggttgtat
      241 tcccacttca tctttccaga ccatcctagg aaatactagg aatccttgga agggaaagaa
      301 ggaacattgt tggttggaat aaaaacaggg ttgaatgagt tccagaaagc aggcttctca
      361 aactcgtgga caacaatctg ctgaagaaga caactttaag aaaccaactc gaagcaatat
      421 gcagagaagt aagatgagag gagctgcctc gggaaagaag tcagctggtt cgcagccaaa
      481 gaatctcgat ccagccctgc ccggaagatg gggaggtcgc tctgctgaga accccccttc
      541 cggttctgtg cggaagacca ggaagaacaa gcagaaggct cctggcaacg gagacggagg
      601 cagtaccagt gaagtccccc agccccctcg gaagaaaagg gcacgggctg accccactgt
      661 ggagagcgag gaggcattca agagtaggat ggaggtgaag gtgaagatcc ctgaagaatt
      721 aaaaccgtgg ctggtggagg actgggactt ggttacgagg cagaagcagt tgttccagct
      781 ccctgctaaa aagaatgtcg atgccattct tgaggagtat gccaattgta agaagtcgca
      841 gggaaatgtt gataataagg agtacgcagt taatgaagtt gtaggaggga taaaagagta
      901 tttcaatgtg atgctgggca ctcagctgct gtacaagttt gaaaggcctc agtatgctga
      961 gattctgctg gctcaccctg atgcgccgat gtcgcagatc tatggggcgc cacacctcct
     1021 gagattattc gtgagaattg gggcaatgtt ggcctatacg ccccttgatg agaaaagcct
     1081 ggcattattg ctgggctatc tgcatgattt ccttaagtat ctggcaaaga attctgcctc
     1141 tctgtttact gccagtgatt acaaagtggc ttctgctgac tatcatcgca aagccctgtg
     1201 aaggtctact gaccgctcac tattgtctgg tatctgtaaa cacttctgtt tagtcctttc
     1261 atggtataat tgatgttctt taaaactgtc agtgtaaaac agggcttatg tttcagtttg
     1321 ttttcctgtt ctgttgtaga cagaaaataa aaggagtgcc cagctccttt cctcatttca
     1381 aagttgctac cagtgtatgc agtaattaga caaagaagaa attcagtaga ccattttatt
     1441 gcctagttga caacattgct tgaatgctgg tggttctatc cctttgacac tacacagttt
     1501 tctaatatgt gttaatgcta cgtgatgaga tgccctggtt cctagtgcca aaggttcaac
     1561 ttaatgtata tacctggaaa cccatgcatt tgtgcttttt ttttttttat ggtgcttgac
     1621 gtctgtaaac agcccatcct ctgcaagtcc atctttgttg ttccttaggc attcattcta
     1681 tctttgctca aattgttgaa ggatggtgat ttgtttcctg gtttttgtat ttgagtctaa
     1741 tgcacgttct aacatgatag aggcaatgca ttattgtgta gccacagttt tctgaaaagt
     1801 tgatatttta ggaattgtat ttcagatctt aaataaaact tgtttctaaa tttcaaagca
     1861 aaaaaaaaaa aaaaaaaaaa
//
