LOCUS       NM_177719               3710 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus microrchidia 2B (Morc2b), transcript variant 2, mRNA.
ACCESSION   NM_177719
VERSION     NM_177719.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3710)
  AUTHORS   Shi,B., Xue,J., Zhou,J., Kasowitz,S.D., Zhang,Y., Liang,G.,
            Guan,Y., Shi,Q., Liu,M., Sha,J., Huang,X. and Wang,P.J.
  TITLE     MORC2B is essential for meiotic progression and fertility
  JOURNAL   PLoS Genet 14 (1), e1007175 (2018)
   PUBMED   29329290
  REMARK    GeneRIF: Morc2b, a relatively recent gene, has evolved an essential
            role in meiosis and fertility.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3710)
  AUTHORS   Hayashi,K., Yoshida,K. and Matsui,Y.
  TITLE     A histone H3 methyltransferase controls epigenetic events required
            for meiotic prophase
  JOURNAL   Nature 438 (7066), 374-378 (2005)
   PUBMED   16292313
REFERENCE   3  (bases 1 to 3710)
  AUTHORS   Abe,K., Yuzuriha,M., Sugimoto,M., Ko,M.S., Brathwaite,M., Waeltz,P.
            and Nagaraja,R.
  TITLE     Gene content of the 750-kb critical region for mouse embryonic
            ectoderm lethal tcl-w5
  JOURNAL   Mamm Genome 15 (4), 265-276 (2004)
   PUBMED   15112104
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK077016.1 and CT033756.22.
            
            On Aug 1, 2009 this sequence version replaced NM_177719.3.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Both variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK077016.1, BB616357.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN00849390
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-727               AK077016.1         2-728
            728-728             CT033756.22        66526-66526         c
            729-2693            AK077016.1         730-2694
            2694-2694           CT033756.22        64560-64560         c
            2695-3330           AK077016.1         2696-3331
            3331-3331           CT033756.22        63923-63923         c
            3332-3708           AK077016.1         3333-3709
            3709-3710           CT033756.22        63544-63545         c
FEATURES             Location/Qualifiers
     source          1..3710
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 17.98 cM"
     gene            1..3710
                     /gene="Morc2b"
                     /gene_synonym="4932411A10Rik; Tce6"
                     /note="microrchidia 2B"
                     /db_xref="GeneID:240069"
                     /db_xref="MGI:MGI:3045293"
     exon            1..477
                     /gene="Morc2b"
                     /gene_synonym="4932411A10Rik; Tce6"
                     /inference="alignment:Splign:2.1.0"
     exon            478..3710
                     /gene="Morc2b"
                     /gene_synonym="4932411A10Rik; Tce6"
                     /inference="alignment:Splign:2.1.0"
     CDS             504..3572
                     /gene="Morc2b"
                     /gene_synonym="4932411A10Rik; Tce6"
                     /EC_number="3.6.1.3"
                     /note="MORC family CW-type zinc finger protein 2B;
                     Morc-like protein"
                     /codon_start=1
                     /product="ATPase MORC2B"
                     /protein_id="NP_808387.2"
                     /db_xref="CCDS:CCDS37561.1"
                     /db_xref="GeneID:240069"
                     /db_xref="MGI:MGI:3045293"
                     /translation="MAFTNYSTLNRAQLTFDYLHTNSTTHAFLFGALAELIDNARDAD
                     ATRIDIYAEKREDLQGGFMLCFLDNGVGMDPNDVINVIQFGKSAKRTPESTQIGRYGN
                     GLKSGSMRIGKDFILFTKKENTMSCLFLSRTFHEEEGIDEVIVPLPTWNSQTREPVTD
                     NMEKFAIETELIYKYSPFHTEEEVMTQFTKISGTSGTLVVIFNLKLTDNGEPELDVTS
                     NPKDIRMAEISQEGVKPERHSFCAYAAVLYIDPRMRIFIHGHKVQTKKLCCCLYKPRK
                     YTFTSHRFKTRAEQEVKKADQVAQLAEEKAREAESKARTLEIHMGGDITRDSRVMLRQ
                     VQNTAITLRREADVKKRIRDAKQQALKEPKELTFVFGVNIEHRDHDGMFIYNCSRLIK
                     MYEKVGPQLEKGMVCGGVVGVIDVPYLVLEPTHNKQDFADAKEYRHLLRAMGEHLAQY
                     WKDIEIAQHGIIKFWDEFGYLSANWNRPPSDELHFKRKRAMQVPTTIQCDLCLKWRTL
                     PFQLSAVEEGYPINWVCSMNPDPEQDQCEAFELKQKIPLGILKKAPKTQEERQKQLTE
                     KIQQEQRKLKALKKIKPIHSQSDLKKLPLEVTSRPFSKYPAHIFQGPQSSFHVVKTNA
                     RRRPQSRHAPFRQLQRSSIICTNPKPPFLVDKTEAVLLQPPETPQKSVSLLVKTIPQP
                     PPLVQSLSPSVVPKSNNPWKVETPQIMNTPVAEMPYVPVNPSLVICDHKRSPEVSDEI
                     EDEDRRKRMCKRGRFTVKKEKIQASELSDSSGEENPVDLKTAQKDKGLYVEVRMMGEC
                     YKGHVTAVEVGDNVVWWKVKFEDMPKDSTPRDCWVEKGSENVWLVKPSPEYQSTDEQQ
                     EDRKGEEDTVVQQALALQQTSTSECFCTEPDTTASTANHKTIDLLVQILWNCLHYFMP
                     LSFPISKKELGAMNSEELLSLPLKECFKQYEVGLQNLCRSYQRCADSQAKVSEESLRI
                     SQKKLQETEEKLQKLRTNIQTLLQMAQQGINIRADDELDAYIEDLVSSDD"
ORIGIN      
        1 attctaaaca gagggacaag ggcttctggg agttgtggcc agtggccggc cagtgcgcac
       61 aagctggtta gtggtgcggt tgcaactgtc ctacaccttg ggtctcagcc ttgcaagctg
      121 agactcactc ctcccggaga gggggaagta gctgcaggat cccaagtcgg acagggaatg
      181 gtgtaggacc atagccagcc acgtaagatt tgggtgggtc tgttatgagg agtttctgtt
      241 gactactgtg aggtcatttc acagagcacc ctgtggtgat tgtggcataa cattaaactg
      301 ggtttgaatt tgaaagactg gtaaggaatc acaaagacct tttttcagtt gccaaatggg
      361 ataccggatg tacaactatc tacgctgtga aaggaccttc tagtactaca gctattaaag
      421 aatagtgaag atgtagatga aagttaagtt tcctggtaga cgtcgatttc cacactggta
      481 agactggagg cttcatttga gtcatggcgt ttaccaatta cagcactctc aaccgggctc
      541 aactaacctt tgactatcta cacacaaatt caactaccca tgcatttttg tttggtgctc
      601 ttgctgaact gattgataat gcgagggatg ctgatgccac ccggatagat atttacgctg
      661 aaaagcgaga ggaccttcaa ggaggattca tgctttgttt tctggataat ggagtcggaa
      721 tggatccaaa cgatgtcatc aatgtgatcc agtttgggaa atcagccaaa cgaacaccag
      781 agtccacaca gattgggcgg tacgggaatg gactaaaatc aggctcaatg cgtattggga
      841 aggattttat cctcttcact aagaaagaaa acaccatgag ttgcctcttc ctgtctcgaa
      901 cctttcatga ggaagaaggc attgatgagg tgatagtccc tttgcctact tggaatagtc
      961 agacacgaga acctgtcaca gataacatgg agaagtttgc cattgagaca gagctcatct
     1021 acaagtattc tcccttccac actgaggaag aagtgatgac ccagtttaca aagatttctg
     1081 ggactagtgg aaccctggtc gtcattttca atctcaaact cacggacaac ggagaacccg
     1141 aactagacgt aacctcaaat ccaaaagata tccggatggc agagatctcc caagaaggcg
     1201 tgaagccaga gcggcactcc ttctgtgcct acgctgctgt gctgtatatc gatcctcgga
     1261 tgaggatttt tattcacggg cacaaggtgc agaccaaaaa gctctgctgc tgcctgtata
     1321 aacccaggaa gtacaccttc acgtcacacc gttttaagac cagggcagaa caagaggtga
     1381 agaaggcaga ccaggtagca cagctcgcgg aagagaaggc ccgggaagca gagagcaaag
     1441 cccgtacatt agaaatacac atgggtggag acatcacccg ggactccagg gtgatgttgc
     1501 gtcaggtcca gaatacagcc atcactctcc gaagagaagc tgatgtcaag aaaaggatca
     1561 gagacgccaa gcagcaagca ctcaaagaac ctaaggagct gacttttgtt tttggtgtca
     1621 acattgaaca ccgtgaccat gatggcatgt ttatctacaa ctgtagccgc ctgatcaaaa
     1681 tgtatgagaa agtgggccca cagctggaaa agggcatggt atgtggtggg gttgttggag
     1741 tcattgatgt gccctacttg gtcctggaac ctacacataa caagcaagac tttgctgatg
     1801 ccaaggagta ccgccacctt ctgcgggcaa tgggggagca cctggcacag tactggaagg
     1861 acatagaaat tgcccagcat ggaattatta agttctggga tgagtttggc tacctttcag
     1921 ctaactggaa cagaccccca tctgatgagt tgcatttcaa acgcaagagg gctatgcaag
     1981 tcccaaccac tatacagtgt gatttatgtc taaagtggag gaccctcccc ttccagttaa
     2041 gtgctgtaga agaaggttac cccatcaact gggtttgttc catgaaccct gatcctgaac
     2101 aggaccagtg tgaggctttt gaactgaagc agaagattcc tctggggata ttaaaaaagg
     2161 ccccgaagac acaggaagaa agacagaagc agctgacaga gaaaattcaa caggagcaga
     2221 ggaagcttaa ggccctcaag aaaatcaagc ctatccattc acaaagcgac ctaaaaaaat
     2281 tacccttgga agtgacttcc agacctttct ccaaatatcc tgctcatata tttcagggtc
     2341 ctcagtcgtc tttccatgta gtaaaaacga atgcccgacg aagacctcag tccaggcatg
     2401 ctccattcag acagctccaa aggtcttcta tcatctgcac caatccaaaa cctccttttc
     2461 tggtagacaa aacagaggct gtgctgctcc agccacccga gacaccccaa aagtcagtga
     2521 gcctcctggt caaaactata ccccaacccc cacctctggt acaatccctg tcaccatctg
     2581 tagtccccaa gtccaacaac ccttggaagg tcgaaactcc ccaaatcatg aacactccag
     2641 tggccgagat gccatatgta cctgttaatc cttcactggt gatttgtgat cataagcgga
     2701 gtcctgaggt ctctgatgaa atagaagatg aagacaggag gaagaggatg tgcaagcggg
     2761 gcaggtttac tgtgaaaaaa gaaaagattc aagcaagtga gctctcagac agctctgggg
     2821 aagagaatcc agttgacctc aagacagctc agaaagataa agggctgtat gtggaggtac
     2881 gtatgatggg agagtgctac aagggccatg tcacagctgt ggaggtgggt gataatgtgg
     2941 tatggtggaa ggtcaagttt gaggatatgc ccaaggatag cacaccaaga gactgctggg
     3001 tggaaaaggg cagtgaaaat gtatggctag tgaagccatc tccagagtac cagagcactg
     3061 atgaacagca agaggataga aagggggagg aggacactgt ggtccagcag gctttggcac
     3121 tgcagcagac ctccacctct gaatgcttct gcactgaacc cgacactact gcctcaacag
     3181 ccaaccacaa gaccattgac ctcttggtcc aaattctctg gaactgccta cattatttca
     3241 tgcctctgag ttttcccata tccaagaagg agctaggtgc catgaattca gaagaattac
     3301 tgtctctccc tctgaaagag tgcttcaagc aatatgaagt cggactccag aatctctgcc
     3361 gctcctacca aagatgtgct gactcacaag ccaaggtctc tgaggaaagc ctgcgcatct
     3421 cccagaaaaa actccaggaa acagaggaga aactccagaa gctgaggacc aacattcaga
     3481 cgctcctgca aatggctcag cagggcataa acatcagggc agatgatgag ctagatgcct
     3541 acattgagga tcttgtcagc agtgatgact gagggacatc aaaagagatc agctctcctc
     3601 ctcaaaactt ccacagtctc tgtggaggga agtttcattc atgtgttttg ggagggggac
     3661 tctggtcctt tgaatcttcc tccctgaatt tataaatatt tttaaagatt
//
